#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y243	uniprotkb:Q96N67	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-2433703|uniprotkb:Q00M63|uniprotkb:Q2PPY7|uniprotkb:Q45RE8|uniprotkb:Q45RE9|uniprotkb:Q5T1B9|uniprotkb:Q5T1C0|uniprotkb:Q6ZV32|uniprotkb:Q8TB82|uniprotkb:Q96NG6|uniprotkb:Q9C092|intact:EBI-7303260|intact:MINT-1683616|uniprotkb:Q96NI0|intact:EBI-28980506|ensembl:ENSP00000489124	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:dock7_human(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:XP_011540628.1|refseq:NP_001258931.1|refseq:NP_212132.2|ensembl:ENST00000251157|ensembl:ENSP00000251157|ensembl:ENST00000340370|ensembl:ENSP00000340742|ensembl:ENST00000404627|ensembl:ENSP00000384446|ensembl:ENST00000454575|ensembl:ENSP00000413583|ensembl:ENST00000634264|ensembl:ENSP00000489284|ensembl:ENST00000635123|ensembl:ENSP00000489499|ensembl:ENSP00000489124|refseq:NP_001258928.1|refseq:NP_001258929.1|refseq:NP_001258930.1|refseq:NP_001317543.1|ensembl:ENSG00000116641(gene)|ensembl:ENST00000635253(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0045178"(basal part of cell)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|mint:Q96N67|rcsb pdb:6AJ4|rcsb pdb:6AJL|reactome:R-HSA-8875555|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:PHjIS0j8JJ6Il3knhzjCzMNkxKk9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:Q8N556	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-3893163|uniprotkb:A8K442|uniprotkb:Q59EY5|uniprotkb:Q9HBY1|uniprotkb:B4DMU2|uniprotkb:E9PDT7|ensembl:ENSP00000351245|ensembl:ENSP00000353402	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:afap1_human(display_long)|uniprotkb:AFAP1(gene name)|psi-mi:AFAP1(display_short)|uniprotkb:AFAP(gene name synonym)|uniprotkb:110 kDa actin filament-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:XP_011511846.1|refseq:NP_001128119.1|refseq:NP_940997.1|ensembl:ENSG00000196526(gene)|ensembl:ENST00000358461(transcript)|ensembl:ENST00000360265(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029907|interpro:IPR030113	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:RhPsp6U+J4FoLPSuXCw0KChvMOg9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:Q7RTP6	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-2555582|uniprotkb:E9PEF0|uniprotkb:Q5U4P4|uniprotkb:Q6ICK4|uniprotkb:Q9P2I3|intact:EBI-2558651|uniprotkb:O94909|uniprotkb:Q96DF2|ensembl:ENSP00000416015|uniprotkb:B2RXJ5	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:mica3_human(display_long)|uniprotkb:KIAA0819(gene name synonym)|uniprotkb:KIAA1364(gene name synonym)|uniprotkb:MICAL3(gene name)|psi-mi:MICAL3(display_short)|uniprotkb:Molecule interacting with CasL protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_001116203.1|refseq:NP_056056.2|go:"GO:0007049"(cell cycle)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042995"(cell projection)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071949"(FAD binding)|go:"GO:0090543"(Flemming body)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR029941|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2D88|rcsb pdb:5SZG|rcsb pdb:6ICI|go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000243156(gene)|ensembl:ENST00000441493(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|refseq:NP_001129476.1|refseq:XP_005261319.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:Ve1WEQHry/REv1IzmmnyGGYd5No9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:Q14254	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-348613|ensembl:ENSP00000378368	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_004466.2|ensembl:ENSG00000132589(gene)|go:"GO:0008544"(epidermis development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|ensembl:ENST00000394908(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:Q05682	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P98082	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-1171238|uniprotkb:Q13598|uniprotkb:Q9BTY0|uniprotkb:Q9UK04|uniprotkb:A6NES5|intact:EBI-28967074|ensembl:ENSP00000313391	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:dab2_human(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	ensembl:ENSP00000313391|ensembl:ENST00000339788|ensembl:ENSP00000345508|ensembl:ENST00000509337|ensembl:ENSP00000426245|ensembl:ENST00000545653|ensembl:ENSP00000439919|refseq:NP_001334.2|refseq:NP_001231800.1|ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2LSW|rcsb pdb:6O5O|rcsb pdb:6OVF|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-45617N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P63010	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-432924|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-28970775|ensembl:ENSP00000482315|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_001025177.1|refseq:NP_001273.1|ensembl:ENST00000610402|ensembl:ENSP00000483185|ensembl:ENST00000618940|ensembl:ENSP00000482835|ensembl:ENSP00000482315|go:"GO:0005048"(signal sequence binding)|go:"GO:0005829"(cytosol)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000621914(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|refseq:XP_011522757.1|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035904"(aorta development)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0005886"(plasma membrane)|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_016879773.1|refseq:XP_016879775.1|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV8|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|dip:DIP-33098N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P61513	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:0kwO2cVd99FGF2+5FyWo94C83049606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P53621	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P47756	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P24844	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-716193|uniprotkb:Q9BQL9|uniprotkb:Q9BUF9|uniprotkb:Q9H136|uniprotkb:E1P5T6|ensembl:ENSP00000279022	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:myl9_human(display_long)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC1(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2C(gene name synonym)|uniprotkb:20 kDa myosin light chain(gene name synonym)|uniprotkb:MYL9(gene name)|psi-mi:MYL9(display_short)|uniprotkb:MRLC1(gene name synonym)|uniprotkb:MYRL2(gene name synonym)|uniprotkb:MLC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_006088.2|refseq:NP_852667.1|ensembl:ENSG00000101335(gene)|ensembl:ENST00000279022(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0070527"(platelet aggregation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P24844|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-8936459|dip:DIP-60525N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:FeJb0ac0n3hkVmRDnxeGSlL2/A89606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P21333	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P16070	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-490245|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370|ensembl:ENSP00000398632	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|ensembl:ENSG00000026508(gene)|ensembl:ENST00000428726(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051216"(cartilage development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|dip:DIP-1121N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:P06396	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:O75128	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-3446582|uniprotkb:A4D257|uniprotkb:B7ZLW9|uniprotkb:B9EGF8|uniprotkb:Q8TCM1|uniprotkb:Q8N304|uniprotkb:A7E2B0|uniprotkb:Q86XA7|uniprotkb:Q504Y4|uniprotkb:Q2T9J3|intact:EBI-28974386|ensembl:ENSP00000265136	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:cobl_human(display_long)|uniprotkb:COBL(gene name)|psi-mi:COBL(display_short)|uniprotkb:KIAA0633(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	ensembl:ENSP00000265136|ensembl:ENST00000395540|ensembl:ENSP00000378910|ensembl:ENST00000395542|ensembl:ENSP00000378912|ensembl:ENST00000441453|ensembl:ENSP00000399500|refseq:XP_011513537.1|refseq:NP_056013.2|refseq:NP_001274365.1|refseq:NP_001274367.1|refseq:NP_001333370.1|refseq:NP_001333371.1|refseq:NP_001333372.1|refseq:NP_001333373.1|ensembl:ENSG00000106078(gene)|ensembl:ENST00000265136(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001726"(ruffle)|go:"GO:0001757"(somite specification)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016020"(membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030903"(notochord development)|go:"GO:0033504"(floor plate development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048565"(digestive tract development)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0051639"(actin filament network formation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990357"(terminal web)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|mint:O75128|rcsb pdb:4PL8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:mkEX2B5sVoK8CD6RWVVCp912otg9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:O75083	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:O43795	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-351119|uniprotkb:O43794|uniprotkb:Q7Z6L5|ensembl:ENSP00000306382|ensembl:ENSP00000376132	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:myo1b_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MYH-1c(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	refseq:NP_001123630.1|refseq:NP_001155291.1|refseq:NP_036355.2|ensembl:ENSG00000128641(gene)|ensembl:ENST00000304164(transcript)|ensembl:ENST00000392318(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O43795|go:"GO:0016459"(myosin complex)|refseq:XP_005246629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:FYYccaCMhkmUdTdtq4M8zdpFpV89606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:K7ENT6	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-21257974|ensembl:ENSP00000467087	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:k7ent6_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	ensembl:ENSG00000167460(gene)|ensembl:ENST00000586833(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:XP_011526533.1|refseq:XP_016882678.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:jIv0VHn6SEMHjGl4RfAAdcgdIN89606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:F5H7S3	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-21257963|ensembl:ENSP00000322577	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:f5h7s3_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	ensembl:ENSG00000140416(gene)|ensembl:ENST00000317516(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR000533(Tropomyosin)|refseq:NP_001317280.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:Xck0zh7JpqM6KjZcOaUvFulRo4U9606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y243	uniprotkb:A1L390	intact:EBI-296115|uniprotkb:Q0VAA6|uniprotkb:Q5VTI1|uniprotkb:Q5VTI2|uniprotkb:Q96QV3|uniprotkb:Q9UFP5|ensembl:ENSP00000263826|ensembl:ENSP00000479081|ensembl:ENSP00000500582|ensembl:ENSP00000505276	intact:EBI-4401429|ensembl:ENSP00000247226|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790	psi-mi:akt3_human(display_long)|uniprotkb:AKT3(gene name)|psi-mi:AKT3(display_short)|uniprotkb:PKBG(gene name synonym)|uniprotkb:RAC-PK-gamma(gene name synonym)|uniprotkb:Protein kinase Akt-3(gene name synonym)|uniprotkb:Protein kinase B gamma(gene name synonym)|uniprotkb:STK-2(gene name synonym)	psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21257982|imex:IM-26691-141	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193658.1|refseq:NP_005456.1|refseq:NP_859029.1|refseq:XP_005273051.1|refseq:XP_005273052.1|dip:DIP-32584N|ensembl:ENSG00000117020(gene)|ensembl:ENSG00000275199(gene)|ensembl:ENST00000263826(transcript)|ensembl:ENST00000621586(transcript)|ensembl:ENST00000673466(transcript)|ensembl:ENST00000680118(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-211163|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034675|interpro:IPR039026|interpro:IPR039029|mint:Q9Y243|rcsb pdb:2X18|reactome:R-HSA-111447|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418	ensembl:ENSG00000126822(gene)|ensembl:ENST00000247226(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|ensembl:ENSP00000247226|ensembl:ENST00000394691|ensembl:ENSP00000378183|refseq:XP_016876646.1|refseq:NP_001295076.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:pwxyw/nuFIUqnuBVKH3HNoNW7309606	rogid:+obep09w4klmkB8i13aA5FQW2609606	rigid:m9Wb7DMxKLS+X9dLJWVuVSFj84M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q8N5N7	intact:EBI-347640|uniprotkb:O43672	intact:EBI-7825175|uniprotkb:B7Z358|ensembl:ENSP00000363999|uniprotkb:Q9NX15|intact:UNK-5522445|uniprotkb:Q5T7E0	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm50_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL50(gene name synonym)|uniprotkb:MRPL50(gene name)|psi-mi:MRPL50(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000136897(gene)|ensembl:ENST00000374865(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR018305|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0|refseq:NP_061924.1	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:Qo0MGo2Bv7DnWEFNu0IPOnGXoWE9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q4U2R6	intact:EBI-347640|uniprotkb:O43672	intact:EBI-7825372|ensembl:ENSP00000229238|uniprotkb:Q9P0N7|uniprotkb:Q9BQ36|uniprotkb:Q96Q57|intact:MINT-6775055	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm51_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL51(gene name synonym)|uniprotkb:MRPL51(gene name)|psi-mi:MRPL51(display_short)|uniprotkb:MRP64(gene name synonym)|uniprotkb:bMRP-64(gene name synonym)|uniprotkb:CDA09(orf name)|uniprotkb:HSPC241(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000111639(gene)|ensembl:ENST00000229238(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019373|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057581.2	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:Jmv8XkomwgJeeYC7B5An8nd12AE9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:V9GYJ9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258097|ensembl:ENSP00000476840	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:v9gyj9_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000132676(gene)|ensembl:ENST00000497826(transcript)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:50eG8EdAwI2qgx55nzBr77AZ4mg9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y676	intact:EBI-347640|uniprotkb:O43672	intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873|ensembl:ENSP00000383438|ensembl:ENSP00000397790|ensembl:ENSP00000398494|ensembl:ENSP00000402718|ensembl:ENSP00000414972|ensembl:ENSP00000415703	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS40(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_054765.1|dip:DIP-29894N|ensembl:ENSG00000203624(gene)|ensembl:ENSG00000204568(gene)|ensembl:ENSG00000223775(gene)|ensembl:ENSG00000226111(gene)|ensembl:ENSG00000227420(gene)|ensembl:ENSG00000229861(gene)|ensembl:ENSG00000233813(gene)|ensembl:ENST00000259873(transcript)|ensembl:ENST00000327800(transcript)|ensembl:ENST00000412451(transcript)|ensembl:ENST00000426945(transcript)|ensembl:ENST00000430402(transcript)|ensembl:ENST00000451032(transcript)|ensembl:ENST00000454427(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0030054"(cell junction)|go:"GO:0032543"(mitochondrial translation)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|interpro:IPR001648(Ribosomal protein S18)|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|interpro:IPR036870|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|interpro:IPR040054|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|mint:Q9Y676	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y3D9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1054270|uniprotkb:Q96Q24|uniprotkb:Q9BWH8|uniprotkb:Q9P053|uniprotkb:B2R6V3|ensembl:ENSP00000320184	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt23_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS23(gene name synonym)|uniprotkb:CGI-138(orf name)|uniprotkb:HSPC329(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_057154.2|ensembl:ENSG00000181610(gene)|ensembl:ENST00000313608(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0031965"(nuclear membrane)|interpro:IPR019520|interpro:IPR023611|mint:Q9Y3D9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:6Iyu6KkT1Y0+n0LKWy5Gf0DkhHw9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y3D5	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5453854|ensembl:ENSP00000295491	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt18c_human(display_long)|uniprotkb:MRPS18C(gene name)|psi-mi:MRPS18C(display_short)|uniprotkb:28S ribosomal protein S18-1, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18c(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18m(gene name synonym)|uniprotkb:CGI-134(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001284698.1|refseq:NP_001284699.1|refseq:NP_057151.1|ensembl:ENSG00000163319(gene)|ensembl:ENST00000295491(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001648(Ribosomal protein S18)|interpro:IPR018275|interpro:IPR036870|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:WFVJqLIjMUdsPmYVjn7uvIxy+c49606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y3D3	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1049319|uniprotkb:Q96Q60|ensembl:ENSP00000362036|uniprotkb:B4E032	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt16_human(display_long)|uniprotkb:MRPS16(gene name)|psi-mi:MRPS16(display_short)|uniprotkb:RPMS16(gene name synonym)|uniprotkb:CGI-132(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS16m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_057149.1|ensembl:ENSG00000182180(gene)|ensembl:ENST00000372945(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|mint:Q9Y3D3|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|rcsb pdb:7A5F|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5G	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:jejigKZMzvzmWuhMXnBB3lNsShU9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y3B7	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5453723|ensembl:ENSP00000308897|uniprotkb:A8K219|uniprotkb:Q32P46|uniprotkb:Q96Q73|uniprotkb:A6NLT0	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm11_human(display_long)|uniprotkb:MRPL11(gene name)|psi-mi:MRPL11(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL11m(gene name synonym)|uniprotkb:CGI-113(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000174547(gene)|ensembl:ENST00000310999(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020784|interpro:IPR036769|interpro:IPR036796|mint:Q9Y3B7|refseq:NP_057134.1|refseq:NP_733934.1|refseq:NP_733935.1|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:eTr4vzze0vg1fxw97n9C/lXYssU9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y399	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y2W1	intact:EBI-347640|uniprotkb:O43672	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634|ensembl:ENSP00000433825	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_005110.2|ensembl:ENSG00000054118(gene)|ensembl:ENST00000354618(transcript)|ensembl:ENST00000469141(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026667|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|refseq:NP_001308400.1|refseq:NP_001308402.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9Y2R9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9P0M9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5325236|ensembl:ENSP00000225969|uniprotkb:B2RE14	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm27_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein bL27m(gene name synonym)|uniprotkb:HSPC250(orf name)|uniprotkb:MRPL27(gene name)|psi-mi:MRPL27(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	mint:Q9P0M9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|ensembl:ENSG00000108826(gene)|ensembl:ENST00000225969(transcript)|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|interpro:IPR001684(Ribosomal protein L27)|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057588.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:Tb7r8GeSkNdNN6aY2mvmTR4MFmc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9NZB2	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9H0U6	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2560240|uniprotkb:Q5TAP9|uniprotkb:Q9NZW8|ensembl:ENSP00000356001	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm18_human(display_long)|uniprotkb:MRPL18(gene name)|psi-mi:MRPL18(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL18m(gene name synonym)|uniprotkb:HSPC071(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_054880.2|ensembl:ENSG00000112110(gene)|ensembl:ENST00000367034(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0035928"(rRNA import into mitochondrion)|interpro:IPR005484(Ribosomal protein L18/L5)|interpro:IPR036967|mint:Q9H0U6|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001305746.1|dip:DIP-56844N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:MtxdrTVdqAfWZqnuxD+PGs218/A9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9BYN8	intact:EBI-347640|uniprotkb:O43672	intact:EBI-721378|uniprotkb:Q96Q58|ensembl:ENSP00000369682	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt26_human(display_long)|uniprotkb:28S ribosomal protein S13, mitochondrial(gene name synonym)|uniprotkb:MRPS26(gene name)|psi-mi:MRPS26(display_short)|uniprotkb:RPMS13(gene name synonym)|uniprotkb:C20orf193(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS26(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_110438.1|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125901(gene)|ensembl:ENST00000380325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR026140|mint:Q9BYN8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:ZygMazfhjHbx+aFhRkeG87c4L6E9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9BYD6	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5325394|ensembl:ENSP00000315017|uniprotkb:A6NG03|uniprotkb:Q4W5B8|uniprotkb:Q6IAG4|uniprotkb:Q96BW3|uniprotkb:Q9H793|uniprotkb:Q9NRL5	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm01_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:BM-022(orf name)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000169288(gene)|ensembl:ENST00000315567(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:Q9BYD6|rcsb pdb:7A5K|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011530500.1|refseq:XP_011530501.1|refseq:NP_064621.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:S5t4UAM2nDToXMl6lV3gh6Ecef09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9BYD2	intact:EBI-347640|uniprotkb:O43672	intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9BY77	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1776152|uniprotkb:Q5H972|uniprotkb:Q6PGN6|uniprotkb:Q7Z6Z0|uniprotkb:Q9NSP5|uniprotkb:Q9NSP6|uniprotkb:A8K6F8|uniprotkb:A8K6V9|uniprotkb:Q009A7|ensembl:ENSP00000252115	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:pdip3_human(display_long)|uniprotkb:POLDIP3(gene name)|psi-mi:POLDIP3(display_short)|uniprotkb:KIAA1649(gene name synonym)|uniprotkb:PDIP46(gene name synonym)|uniprotkb:46 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:S6K1 Aly/REF-like target(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_115687.2|refseq:NP_835237.1|ensembl:ENSG00000100227(gene)|ensembl:ENST00000252115(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034784|interpro:IPR035979|mint:Q9BY77|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:64+Bf4QpCDdKkZMMH/7afOnOKH09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q9BRJ2	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2514313|ensembl:ENSP00000483030|uniprotkb:Q6ZMJ5|uniprotkb:A1L436	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm45_human(display_long)|uniprotkb:MRPL45(gene name)|psi-mi:MRPL45(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL45(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000277936(gene)|ensembl:ENST00000621878(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR032710|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|dip:DIP-53786N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:9NtO1r7W7U9BW3vB9RTRbwehBZ49606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q99873	intact:EBI-347640|uniprotkb:O43672	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q96FV9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1765605|uniprotkb:Q15219|uniprotkb:B2RBP6|uniprotkb:Q64I72|uniprotkb:Q64I73|intact:EBI-28984554|ensembl:ENSP00000261600	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:thoc1_human(display_long)|uniprotkb:hTREX84(gene name synonym)|uniprotkb:THOC1(gene name)|psi-mi:THOC1(display_short)|uniprotkb:HPR1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_005122.2|ensembl:ENSP00000261600|ensembl:ENSG00000079134(gene)|ensembl:ENST00000261600(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q96FV9|rcsb pdb:1WXP|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:D+lk5iFzcmd1bQRa2cx/nUyq4sI9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q96EY7	intact:EBI-347640|uniprotkb:O43672	intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q92665	intact:EBI-347640|uniprotkb:O43672	intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q92552	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q8TCC3	intact:EBI-347640|uniprotkb:O43672	intact:EBI-11038252|uniprotkb:Q9P0N0|uniprotkb:A6NIC6|uniprotkb:D3DVI0|uniprotkb:Q0D2Q7|uniprotkb:Q6ZTP4|uniprotkb:Q96Q69|uniprotkb:D3DVI3|ensembl:ENSP00000338057|ensembl:ENSP00000386752	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm30_human(display_long)|uniprotkb:MRPL30(gene name)|psi-mi:MRPL30(display_short)|uniprotkb:39S ribosomal protein L28, mitochondrial(gene name synonym)|uniprotkb:MRPL28(gene name synonym)|uniprotkb:RPML28(gene name synonym)|uniprotkb:HSPC249(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL30m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_660213.1|interpro:IPR036919|mint:Q8TCC3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|interpro:IPR016082(Ribosomal protein L30, C-terminal)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000185414(gene)|ensembl:ENST00000338148(transcript)|ensembl:ENST00000409841(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR005996(Ribosomal protein L30, bacterial-type)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:B9fWF4LjIKSO3Cg2+oLuH2KQjfE9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q8NI27	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1755078|intact:EBI-2802903|uniprotkb:A6NM50|uniprotkb:Q9H8I6|uniprotkb:Q5JZ12|uniprotkb:Q6IN92|ensembl:ENSP00000245838|ensembl:ENSP00000347959	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:thoc2_human(display_long)|uniprotkb:hTREX120(gene name synonym)|uniprotkb:THOC2(gene name)|psi-mi:THOC2(display_short)|uniprotkb:CXorf3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001075019.1|ensembl:ENSG00000125676(gene)|ensembl:ENST00000245838(transcript)|ensembl:ENST00000355725(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048666"(neuron development)|go:"GO:0048699"(generation of neurons)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|mint:Q8NI27|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:GJCI/aEu/upu9s/gMVJvt56PXP89606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q8N983	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1043145|ensembl:ENSP00000315364|uniprotkb:Q5JW06|uniprotkb:Q7Z719|uniprotkb:Q7Z7H6|uniprotkb:Q86XN1|uniprotkb:Q9BYC7|uniprotkb:B1AL09|uniprotkb:B1AL07|uniprotkb:B1AL10|intact:EBI-1047104|uniprotkb:D3DR71|uniprotkb:B1AL06|uniprotkb:C9J5Q3	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm43_human(display_long)|uniprotkb:Mitochondrial ribosomal protein bMRP36a(gene name synonym)|uniprotkb:MRPL43(gene name)|psi-mi:MRPL43(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|ensembl:ENSG00000055950(gene)|ensembl:ENST00000318325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR039927|mint:Q8N983|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:7A5I|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|refseq:NP_789764.1|refseq:XP_006718098.1|refseq:NP_115488.2|refseq:NP_789762.1|refseq:NP_789763.1|refseq:NP_001295325.1|ensembl:ENST00000299179|ensembl:ENSP00000299179|ensembl:ENSP00000315364|ensembl:ENST00000318364|ensembl:ENSP00000315948|ensembl:ENST00000342071|ensembl:ENSP00000339844|ensembl:ENST00000370234|ensembl:ENSP00000359254|ensembl:ENST00000370236|ensembl:ENSP00000359256|ensembl:ENST00000370242|ensembl:ENSP00000359262|refseq:XP_005270288.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:p3wPkljBAhx4IwvXsvfXDaEvpag9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q86TS9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-10977303|ensembl:ENSP00000347277|uniprotkb:A8MYI6|uniprotkb:Q6NVH8|uniprotkb:G3XCN9|uniprotkb:A6NMQ8|uniprotkb:A8MXK5	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm52_human(display_long)|uniprotkb:MRPL52(gene name)|psi-mi:MRPL52(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL52(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_848026.1|refseq:NP_851313.1|refseq:NP_851821.1|refseq:NP_851822.1|refseq:NP_851823.1|refseq:NP_851824.1|refseq:XP_005267385.1|ensembl:ENSG00000172590(gene)|ensembl:ENST00000355151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR034596|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:43Zs1d7+FuTPn1GioGHjL/kbZUE9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q7Z2W4	intact:EBI-347640|uniprotkb:O43672	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q6I9Y2	intact:EBI-347640|uniprotkb:O43672	intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:15M7nouxNuzlKZPawajrahz0LAY9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q5W012	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258084|ensembl:ENSP00000395448	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:q5w012_human(display_long)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000134453(gene)|ensembl:ENST00000437845(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR040052	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:61YxKA3gAuN6QCpAFyBysWjmYX89606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q14980	intact:EBI-347640|uniprotkb:O43672	intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q14244	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2211064|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3|ensembl:ENSP00000346581	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:XP_016866960.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|ensembl:ENSP00000346581|ensembl:ENST00000432797|ensembl:ENSP00000414879|ensembl:ENST00000438100|ensembl:ENSP00000400790|ensembl:ENST00000454590|ensembl:ENSP00000414712|ensembl:ENST00000544465|ensembl:ENSP00000445737|ensembl:ENST00000611373|ensembl:ENSP00000482998|ensembl:ENST00000616617|ensembl:ENSP00000483511|ensembl:ENST00000618822|ensembl:ENSP00000482356|ensembl:ENSG00000135525(gene)|ensembl:ENST00000354570(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR030707|mint:Q14244	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q13405	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5325200|ensembl:ENSP00000279242|ensembl:ENSP00000434190|uniprotkb:B2R4G6	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm49_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL49(gene name synonym)|uniprotkb:MRPL49(gene name)|psi-mi:MRPL49(display_short)|uniprotkb:C11orf4(gene name synonym)|uniprotkb:NOF1(gene name synonym)|uniprotkb:Neighbor of FAU(gene name synonym)|uniprotkb:Protein NOF1(gene name synonym)|uniprotkb:OK/SW-cl.67(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	interpro:IPR007740(Ribosomal protein L49/IMG2)|mint:Q13405|rcsb pdb:3J7Y|ensembl:ENSG00000149792(gene)|ensembl:ENST00000279242(transcript)|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|ensembl:ENST00000526319(transcript)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6I9R|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|go:"GO:0005762"(mitochondrial large ribosomal subunit)|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|rcsb pdb:7OF6|reactome:R-HSA-5419276|refseq:NP_004918.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:rSs3oQ/ABEywPjx7fwVEuT6fsdQ9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q13084	intact:EBI-347640|uniprotkb:O43672	intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:Q07021	intact:EBI-347640|uniprotkb:O43672	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P84090	intact:EBI-347640|uniprotkb:O43672	intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82933	intact:EBI-347640|uniprotkb:O43672	intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82932	intact:EBI-347640|uniprotkb:O43672	intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82930	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82914	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82675	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82673	intact:EBI-347640|uniprotkb:O43672	intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82663	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P82650	intact:EBI-347640|uniprotkb:O43672	intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P62316	intact:EBI-347640|uniprotkb:O43672	intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P35580	intact:EBI-347640|uniprotkb:O43672	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P14866	intact:EBI-347640|uniprotkb:O43672	intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P09497	intact:EBI-347640|uniprotkb:O43672	intact:EBI-726598|uniprotkb:Q6FHW1|uniprotkb:Q53Y37|ensembl:ENSP00000309415	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:clcb_human(display_long)|uniprotkb:CLTB(gene name)|psi-mi:CLTB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	refseq:NP_001825.1|refseq:NP_009028.1|ensembl:ENSG00000175416(gene)|ensembl:ENST00000310418(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060170"(ciliary membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:xiV7woFwZVVWs+Ter10SElj68V09606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:P09001	intact:EBI-347640|uniprotkb:O43672	intact:EBI-5325418|ensembl:ENSP00000264995|uniprotkb:Q6IBT2	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:rm03_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL3m(gene name synonym)|uniprotkb:MRPL3(gene name)|psi-mi:MRPL3(display_short)|uniprotkb:MRL3(gene name synonym)|uniprotkb:RPML3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000114686(gene)|ensembl:ENST00000264995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P09001|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|interpro:IPR019927|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_009139.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:JsDyyXQz9ZMCkRtp5TuL0PGYCjw9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:O75616	intact:EBI-347640|uniprotkb:O43672	intact:EBI-6393536|ensembl:ENSP00000254928|uniprotkb:B3KN21|uniprotkb:C9JEC6|uniprotkb:O75617|uniprotkb:Q8WUY4|uniprotkb:Q96LE2|uniprotkb:Q96TC0	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:eral1_human(display_long)|uniprotkb:ERAL1(gene name)|psi-mi:ERAL1(display_short)|uniprotkb:HERA(gene name synonym)|uniprotkb:Conserved ERA-like GTPase(gene name synonym)|uniprotkb:ERA-W(gene name synonym)|uniprotkb:ERA-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000132591(gene)|ensembl:ENST00000254928(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005662(GTP-binding protein Era)|interpro:IPR006073(GTP1/OBG)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR027417|interpro:IPR030388|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_005693.1|refseq:NP_001304914.1|refseq:NP_001304915.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:2usCrRc4/GbXG5Ft8GY61w+rGds9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:L0R6D6	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258076	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:l0r6d6_human(display_long)|uniprotkb:C17orf85(gene name)|psi-mi:C17orf85(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003729"(mRNA binding)|interpro:IPR019416|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:i8uF4DYKqk8WpS7tDQuTaqjcT1I9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:H7C5V3	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258068|ensembl:ENSP00000427846	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:h7c5v3_human(display_long)|uniprotkb:MRPS28(gene name)|psi-mi:MRPS28(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000147586(gene)|ensembl:ENST00000518271(transcript)|interpro:IPR019375	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:jRYC0frv/r/EaUP1pUPXbcbjX4w9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:E5RIZ4	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258055|ensembl:ENSP00000429252	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:e5riz4_human(display_long)|uniprotkb:MRPL15(gene name)|psi-mi:MRPL15(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000137547(gene)|ensembl:ENST00000522521(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|interpro:IPR005749(Ribosomal protein L15, bacterial-type)|interpro:IPR021131|interpro:IPR036227	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:WAE5pF74oMXlZ6G59beMJHHwIJc9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:B4DLN1	intact:EBI-347640|uniprotkb:O43672	intact:EBI-11028706|ensembl:ENSP00000461324	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:b4dln1_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	ensembl:ENSG00000262660(gene)|ensembl:ENST00000571730(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR018108|interpro:IPR023395|interpro:IPR036235	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:ONQ1ByBu5w5LjNK6o/VoUQ6HsN89606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:A8K3Q9	intact:EBI-347640|uniprotkb:O43672	intact:EBI-10174314	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:a8k3q9_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	interpro:IPR041985|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:j616/CNgbYEAH+NvWkfjXpZWqo89606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86V81	uniprotkb:A5Y5A3	intact:EBI-347640|uniprotkb:O43672	intact:EBI-21258050	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:a5y5a3_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258109|imex:IM-26691-101	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	interpro:IPR019375|interpro:IPR007327(Tumor protein D52)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rogid:E1eAJfa6apGwWt2MJ5pmGYaXZow9606	rigid:B5PdWE50UtvuZuly+0tv+0PJq18	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:Q9UIV1	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:Q9C0C2	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:Q96LI5	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:2Y605zw41TOo2ATkUM/7ToUb6449606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:Q92600	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-357079|uniprotkb:Q96IX4|uniprotkb:B2RPI0|uniprotkb:B7Z1E5|uniprotkb:B5MDQ4|ensembl:ENSP00000273064|ensembl:ENSP00000443687	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot9_human(display_long)|uniprotkb:Cell differentiation protein RQCD1 homolog(gene name synonym)|uniprotkb:RCD1(gene name synonym)|uniprotkb:RQCD1(gene name synonym)|uniprotkb:CNOT9(gene name)|psi-mi:CNOT9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	dip:DIP-46840N|refseq:NP_005435.1|refseq:NP_001258564.1|refseq:NP_001258563.1|ensembl:ENSG00000144580(gene)|ensembl:ENST00000273064(transcript)|ensembl:ENST00000542068(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:2FV2|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:5LSW|rcsb pdb:5ONA|rcsb pdb:5ONB|rcsb pdb:6HOM|rcsb pdb:6HON|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:/oDjYD0axKIkLMKxmji2q+sg+K49606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:O75175	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3ZCQ2	uniprotkb:A5YKK6	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258299|imex:IM-26691-81	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rigid:3EO/Bnvo9saJ4zTV8V7vrWZtYTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P78540	uniprotkb:Q9UL15	intact:EBI-9056613|uniprotkb:B2R690|uniprotkb:Q6FHY8|ensembl:ENSP00000261783	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:argi2_human(display_long)|uniprotkb:ARG2(gene name)|psi-mi:ARG2(display_short)|uniprotkb:Kidney-type arginase(gene name synonym)|uniprotkb:Non-hepatic arginase(gene name synonym)|uniprotkb:Type II arginase(gene name synonym)|uniprotkb:Arginase II(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258323|imex:IM-26691-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163.1|ensembl:ENSG00000081181(gene)|ensembl:ENST00000261783(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0045087"(innate immune response)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:0071644"("negative regulation of chemokine (C-C motif) ligand 4 production")|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:1903426"(regulation of reactive oxygen species biosynthetic process)|go:"GO:1905403"(negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|interpro:IPR020855|interpro:IPR023696|rcsb pdb:1PQ3|rcsb pdb:4HZE|rcsb pdb:4I06|rcsb pdb:4IE2|rcsb pdb:4IE3|rcsb pdb:4IXU|rcsb pdb:4IXV|rcsb pdb:6Q37|rcsb pdb:6Q39|rcsb pdb:6SS2|rcsb pdb:6SS4|rcsb pdb:6SS6|reactome:R-HSA-70635	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:AVVSVOCI1bPFUPMjojG4QSwFjIA9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:v4cR/vT6mh4/Mz4AOp63yDjne+8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:Q9BR76	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:Q05682	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P67936	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P52907	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P47755	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P24534	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P17544	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-765623|uniprotkb:Q13814|uniprotkb:Q9UD83|uniprotkb:B4DQL4|uniprotkb:A5D6Y4|uniprotkb:Q8IVR8|uniprotkb:B2RMP1|ensembl:ENSP00000387406|ensembl:ENSP00000399465	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf7_human(display_long)|uniprotkb:Activating transcription factor 7(gene name synonym)|uniprotkb:Transcription factor ATF-A(gene name synonym)|uniprotkb:ATF7(gene name)|psi-mi:ATF7(display_short)|uniprotkb:ATFA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001123532.1|refseq:NP_006847.1|refseq:NP_001193611.1|refseq:NP_001193612.1|refseq:XP_005268644.1|refseq:XP_016874211.1|mint:P17544|ensembl:ENSG00000170653(gene)|ensembl:ENST00000420353(transcript)|ensembl:ENST00000456903(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019899"(enzyme binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:s5AntXnCnlzs9IgBN8cvvNQQd089606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P17535	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:npmTGULvlKr4hC8HfmK19GUopf49606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P17275	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P18847	uniprotkb:P14649	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258332|imex:IM-26691-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:S0/S5hUxfyyve1JDMojIggOSBb89606	rigid:mzjA2Iwgp1CE0uoKCBkTTcZ+4LU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P20719	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719	-	-	comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9Y5R8	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6160554|uniprotkb:D3DTR0|ensembl:ENSP00000441130|ensembl:ENSP00000302783	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tppc1_human(display_long)|uniprotkb:TRAPPC1(gene name)|psi-mi:TRAPPC1(display_short)|uniprotkb:BET5(gene name synonym)|uniprotkb:MUM2(gene name synonym)|uniprotkb:BET5 homolog(gene name synonym)|uniprotkb:Multiple myeloma protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001160093.1|refseq:NP_067033.1|dip:DIP-48285N|ensembl:ENSG00000170043(gene)|ensembl:ENST00000303731(transcript)|ensembl:ENST00000540486(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-6798695|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:GBffndm51mtFULiV5SWwmxv+Bp89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9Y2L1	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9Y296	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-722888|uniprotkb:B4DME1|uniprotkb:A8K3A5|intact:EBI-28967645|ensembl:ENSP00000436005|ensembl:ENSP00000487467	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tppc4_human(display_long)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym)|uniprotkb:Hematopoietic stem/progenitor cell protein 172(gene name synonym)|uniprotkb:TRAPPC4(gene name)|psi-mi:TRAPPC4(display_short)|uniprotkb:SBDN(gene name synonym)|uniprotkb:CGI-104(orf name)|uniprotkb:HSPC172(orf name)|uniprotkb:PTD009(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSP00000487467|ensembl:ENST00000629713|ensembl:ENSP00000486496|refseq:NP_057230.1|ensembl:ENST00000434101|ensembl:ENSP00000405033|ensembl:ENSP00000436005|refseq:NP_001305415.1|refseq:NP_001305417.1|refseq:NP_001305418.1|refseq:NP_001305419.1|refseq:NP_001305421.1|refseq:NP_001305423.1|dip:DIP-37871N|ensembl:ENSG00000196655(gene)|ensembl:ENSG00000280495(gene)|ensembl:ENST00000533632(transcript)|ensembl:ENST00000629243(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016358"(dendrite development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|rcsb pdb:2JSN|rcsb pdb:2ZMV|reactome:R-HSA-204005|reactome:R-HSA-3000170|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:9Dqiz8Vo+JYaAoNESIFFuhf2yc09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9UBS4	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9UBF2	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9P2R7	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9P032	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9NVI1	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9NSE4	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9NR50	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9HCN8	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2339921|uniprotkb:Q9BRI5|uniprotkb:A2RUD3|ensembl:ENSP00000248958	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:sdf2l_human(display_long)|uniprotkb:SDF2L1(gene name)|psi-mi:SDF2L1(display_short)|uniprotkb:PWP1-interacting protein 8(gene name synonym)|uniprotkb:UNQ1941/PRO4424(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_071327.2|ensembl:ENSG00000128228(gene)|ensembl:ENST00000248958(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|mint:Q9HCN8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:0vAPKCqCGpCARkmy7ZsTccxScgk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9BXW7	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-4399500|uniprotkb:B2RCK5|uniprotkb:Q9BXW8|uniprotkb:Q9NWA8|uniprotkb:Q9NX41|ensembl:ENSP00000337358	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:hdhd5_human(display_long)|uniprotkb:HDHD5(gene name)|psi-mi:HDHD5(display_short)|uniprotkb:CECR5(gene name synonym)|uniprotkb:Cat eye syndrome critical region protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_060299.4|refseq:NP_149061.1|ensembl:ENSG00000069998(gene)|ensembl:ENST00000336737(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|interpro:IPR006353(HAD-superfamily hydrolase, subfamily IIA, CECR5)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR029621|interpro:IPR036412|mint:Q9BXW7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:INkCPE3PGW5PVO8j4245B1F99HU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9BSJ2	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9BRK5	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1389808|uniprotkb:Q8NBQ3|uniprotkb:Q9NZP7|uniprotkb:B1AME5|uniprotkb:B2RDF1|uniprotkb:B4DSM1|uniprotkb:Q53G52|uniprotkb:Q53HQ9|uniprotkb:Q96AA1|uniprotkb:Q9UN53|intact:EBI-2511482|uniprotkb:B1AME6	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:cab45_human(display_long)|uniprotkb:Stromal cell-derived factor 4(gene name synonym)|uniprotkb:SDF4(gene name)|psi-mi:SDF4(display_short)|uniprotkb:CAB45(gene name synonym)|uniprotkb:PSEC0034(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_057631.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_011539858.1|interpro:IPR027240|mint:Q9BRK5|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0021549"(cerebellum development)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070625"(zymogen granule exocytosis)|go:"GO:0099558"(maintenance of synapse structure)|refseq:NP_057260.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:wQ0Ov1MDf6p0BmUCZRAS+Na/ERc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q9BQE3	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q99714	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96Q15	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:u7doCYezlcCUKq//xhk0TZ2TD009606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96Q05	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6160596|uniprotkb:Q4VTT3|uniprotkb:Q658K7|uniprotkb:Q6P149|uniprotkb:Q6ZQT3|uniprotkb:Q7L5C4|uniprotkb:Q86Y21|uniprotkb:Q96SL2|uniprotkb:Q9BQA2|ensembl:ENSP00000405060|ensembl:ENSP00000498020	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tppc9_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)|uniprotkb:KIAA1882(gene name synonym)|uniprotkb:NIBP(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym)|uniprotkb:Tularik gene 1 protein(gene name synonym)|uniprotkb:T1(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001308575.1|refseq:NP_001153844.1|refseq:NP_113654.4|ensembl:ENSG00000167632(gene)|ensembl:ENST00000438773(transcript)|ensembl:ENST00000648948(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR013935(Transport protein Trs120)|mint:Q96Q05|reactome:R-HSA-204005|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:LmmBavWplLRKY/Q932T4UijaHRs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96N67	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2433703|uniprotkb:Q00M63|uniprotkb:Q2PPY7|uniprotkb:Q45RE8|uniprotkb:Q45RE9|uniprotkb:Q5T1B9|uniprotkb:Q5T1C0|uniprotkb:Q6ZV32|uniprotkb:Q8TB82|uniprotkb:Q96NG6|uniprotkb:Q9C092|intact:EBI-7303260|intact:MINT-1683616|uniprotkb:Q96NI0|intact:EBI-28980506|ensembl:ENSP00000489124	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:dock7_human(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:XP_011540628.1|refseq:NP_001258931.1|refseq:NP_212132.2|ensembl:ENST00000251157|ensembl:ENSP00000251157|ensembl:ENST00000340370|ensembl:ENSP00000340742|ensembl:ENST00000404627|ensembl:ENSP00000384446|ensembl:ENST00000454575|ensembl:ENSP00000413583|ensembl:ENST00000634264|ensembl:ENSP00000489284|ensembl:ENST00000635123|ensembl:ENSP00000489499|ensembl:ENSP00000489124|refseq:NP_001258928.1|refseq:NP_001258929.1|refseq:NP_001258930.1|refseq:NP_001317543.1|ensembl:ENSG00000116641(gene)|ensembl:ENST00000635253(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0045178"(basal part of cell)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|mint:Q96N67|rcsb pdb:6AJ4|rcsb pdb:6AJL|reactome:R-HSA-8875555|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:PHjIS0j8JJ6Il3knhzjCzMNkxKk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96I99	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2511878|ensembl:ENSP00000307432|uniprotkb:Q8WUQ1|uniprotkb:Q86VX8|uniprotkb:O95195|uniprotkb:Q6NUH7|uniprotkb:C9JVT2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:sucb2_human(display_long)|uniprotkb:SUCLG2(gene name)|psi-mi:SUCLG2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000172340(gene)|ensembl:ENST00000307227(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q96I99|rcsb pdb:6WCV|reactome:R-HSA-71403|refseq:NP_001171070.1|refseq:NP_003839.2|dip:DIP-53563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:jxrFGuu3hFn2QAYfrPxTKhScM249606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96D53	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q96C36	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q969Z0	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q93009	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q92947	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q92900	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q92769	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8WWC4	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8WVR3	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-719893|uniprotkb:Q9BQJ1|uniprotkb:Q9BUB6|uniprotkb:Q9NV47|ensembl:ENSP00000324741|uniprotkb:A4D2A9|uniprotkb:D6W5U4	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tpc14_human(display_long)|uniprotkb:TRAPPC14(gene name)|psi-mi:TRAPPC14(display_short)|uniprotkb:C7orf43(gene name synonym)|uniprotkb:MAP11(gene name synonym)|uniprotkb:Microtubule-associated protein 11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000146826(gene)|ensembl:ENST00000316937(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR031626|refseq:NP_060745.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:PyW56/px1eOOdPlMQMz28SahCWg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8TEX9	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8TB37	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-12852610|ensembl:ENSP00000281081|uniprotkb:B4DHZ1|uniprotkb:Q86TZ4|uniprotkb:Q9H9M2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:nubpl_human(display_long)|uniprotkb:NUBPL(gene name)|psi-mi:NUBPL(display_short)|uniprotkb:C14orf127(gene name synonym)|uniprotkb:IND1 homolog(gene name synonym)|uniprotkb:Nucleotide-binding protein-like(gene name synonym)|uniprotkb:huInd1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000151413(gene)|ensembl:ENST00000281081(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR033756|interpro:IPR044304|reactome:R-HSA-6799198|refseq:NP_001188502.1|refseq:NP_079428.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:e9UiCfG76k75Df7cMDdOmi/LI7I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8NI60	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8NBS9	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:bz5VVWMPFLTRKwph60UFASjsFN49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q8IUR0	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-3246160|ensembl:ENSP00000316990|ensembl:ENSP00000399025|ensembl:ENSP00000470262|uniprotkb:A8K7I6	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tppc5_human(display_long)|uniprotkb:TRAPPC5(gene name)|psi-mi:TRAPPC5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000181029(gene)|ensembl:ENST00000317378(transcript)|ensembl:ENST00000596148(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016696(TRAPP I complex, Trs31)|interpro:IPR024096|reactome:R-HSA-204005|reactome:R-HSA-8876198|ensembl:ENST00000426877(transcript)|refseq:NP_001035926.1|refseq:NP_001035927.1|refseq:NP_777554.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:mojNHWAAx2Vj20UWUjm0UJsHxnQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q86SZ2	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6160531|uniprotkb:B3KPS2|uniprotkb:Q5JPD6|uniprotkb:Q86U35|uniprotkb:Q86X35|ensembl:ENSP00000330289	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tpc6b_human(display_long)|uniprotkb:TRAPPC6B(gene name)|psi-mi:TRAPPC6B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001073005.1|refseq:NP_803235.1|dip:DIP-47626N|ensembl:ENSG00000182400(gene)|ensembl:ENST00000330149(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007399"(nervous system development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|interpro:IPR037992|mint:Q86SZ2|rcsb pdb:2BJN|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:uKQpJ/uSsQpZpbdQ3diIH1XjFXM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q7L8L6	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-747570|uniprotkb:Q96JN3|uniprotkb:Q9H5D1|uniprotkb:Q9H8Y3|ensembl:ENSP00000369618	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:fakd5_human(display_long)|uniprotkb:FASTKD5(gene name)|psi-mi:FASTKD5(display_short)|uniprotkb:KIAA1792(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_068598.1|ensembl:ENSG00000215251(gene)|ensembl:ENST00000380266(transcript)|go:"GO:0000963"(mitochondrial RNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:i48wNX7cmBCPpWXkXfnZhGnrse89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q7L7V1	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2807297|uniprotkb:Q9NV74|uniprotkb:Q96NY1|uniprotkb:Q9NVJ7|uniprotkb:Q9NSL5|uniprotkb:Q9H769|uniprotkb:Q5T3L5|uniprotkb:Q9BUN0|uniprotkb:Q5T3L0|uniprotkb:A8MSV2|uniprotkb:Q49AG5|uniprotkb:D3DRF9|ensembl:ENSP00000284690	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:dhx32_human(display_long)|uniprotkb:DHX32(gene name)|psi-mi:DHX32(display_short)|uniprotkb:DDX32(gene name synonym)|uniprotkb:DEAD/H box 32(gene name synonym)|uniprotkb:DEAD/H helicase-like protein 1(gene name synonym)|uniprotkb:DEAH box protein 32(gene name synonym)|uniprotkb:HuDDX32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_060650.2|refseq:XP_016871893.1|refseq:XP_016871894.1|ensembl:ENSG00000089876(gene)|ensembl:ENST00000284690(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:IQFcD75pd5R0uajIotdMRpGXVeI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q6PGP7	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6083436|uniprotkb:O15077|uniprotkb:Q6PJI3|ensembl:ENSP00000351596|ensembl:ENSP00000497948	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ttc37_human(display_long)|uniprotkb:Tricho-hepatic-enteric syndrome protein(gene name synonym)|uniprotkb:SKI3 homolog(gene name synonym)|uniprotkb:TTC37(gene name)|psi-mi:TTC37(display_short)|uniprotkb:KIAA0372(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_055454.1|ensembl:ENSG00000198677(gene)|ensembl:ENST00000358746(transcript)|ensembl:ENST00000649566(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0035327"|go:"GO:0055087"(Ski complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|mint:Q6PGP7|reactome:R-HSA-429958	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:1vbt+NR8Vmwq7a+9fisoF2WxDbc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q5T160	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1050546|uniprotkb:Q96FU5|uniprotkb:Q9H8K8|uniprotkb:B2RDT7|ensembl:ENSP00000358549	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:syrm_human(display_long)|uniprotkb:RARS2(gene name)|psi-mi:RARS2(display_short)|uniprotkb:RARSL(gene name synonym)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_064716.2|ensembl:ENSG00000146282(gene)|ensembl:ENST00000369536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q5T160|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:jslLCkjYCriiVlR94nHAhNIYVeY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q5JTZ9	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q5HYI8	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000144840(gene)|ensembl:ENST00000273375(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:1903059"(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|go:"GO:0050821"(protein stabilization)|refseq:NP_776186.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q16822	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780|ensembl:ENSP00000494919|uniprotkb:B4DW73	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_001018083.2|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0042594"(response to starvation)|go:"GO:0046327"(glycerol biosynthetic process from pyruvate)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|go:"GO:0030145"(manganese ion binding)|ensembl:ENSG00000100889(gene)|ensembl:ENSG00000285241(gene)|ensembl:ENST00000216780(transcript)|ensembl:ENST00000645217(transcript)|go:"GO:0004611"(phosphoenolpyruvate carboxykinase activity)|go:"GO:0004613"("phosphoenolpyruvate carboxykinase (GTP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019543"(propionate catabolic process)|refseq:NP_004554.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q16576	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q14318	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q13885	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	intact:EBI-20649665	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	-	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tuba3c_tuba3d_human(display_short)|psi-mi:EBI-20649665(display_long)|intact:TUBA3C/TUBA3D(author assigned name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	uniprotkb:P0DPH7(set member)|uniprotkb:P0DPH8(set member)|uniprotkb:Q13748(see-also)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q13576	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q13015	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6269719|ensembl:ENSP00000357917	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q09028	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q08J23	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q08380	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:Q01813	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P78527	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P67775	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P63151	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P61981	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P55809	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2687150|uniprotkb:B7Z528|uniprotkb:B2R5V2|ensembl:ENSP00000196371	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:scot1_human(display_long)|uniprotkb:OXCT(gene name synonym)|uniprotkb:SCOT(gene name synonym)|uniprotkb:OXCT1(gene name)|psi-mi:OXCT1(display_short)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_000427.1|ensembl:ENSG00000083720(gene)|ensembl:ENST00000196371(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|rcsb pdb:3DLX|reactome:R-HSA-77108	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:9kyVQbY3sPBRAfJkkF5HhHZg31c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P55786	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P54886	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P53618	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P53597	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P51617	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P51570	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P49411	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P48553	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P46821	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P45974	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-741277|ensembl:ENSP00000229268|uniprotkb:Q96J22|uniprotkb:D3DUS7|uniprotkb:D3DUS8	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ubp5_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme 5(gene name synonym)|uniprotkb:Isopeptidase T(gene name synonym)|uniprotkb:USP5(gene name)|psi-mi:USP5(display_short)|uniprotkb:ISOT(gene name synonym)|uniprotkb:Ubiquitin thioesterase 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000111667(gene)|ensembl:ENST00000229268(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|interpro:IPR041812|mint:P45974|rcsb pdb:2DAG|rcsb pdb:2DAK|rcsb pdb:2G43|rcsb pdb:2G45|rcsb pdb:3IHP|rcsb pdb:6DXH|rcsb pdb:6DXT|rcsb pdb:6NFT|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|rcsb pdb:6P9G|rcsb pdb:7MS5|rcsb pdb:7MS6|rcsb pdb:7MS7|reactome:R-HSA-5689880|reactome:R-HSA-8866652|refseq:NP_001092006.1|refseq:NP_003472.2|dip:DIP-34459N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:9wmOnaEu1N5ZY3E4UiHp2D9f9j89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P42765	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P42695	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P34897	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P33993	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P32322	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P30153	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P30042	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P27708	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P23258	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-302589|ensembl:ENSP00000251413|uniprotkb:Q9BW59|uniprotkb:Q53X79	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|interpro:IPR017975|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000131462(gene)|ensembl:ENST00000251413(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|go:"GO:0005814"(centriole)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|refseq:NP_001061.2|dip:DIP-29890N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P21912	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P17931	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P17858	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P17812	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P14324	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	intact:EBI-20591397	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	-	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:trappc2_trappc2b_human(display_short)|psi-mi:EBI-20591397(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	-	-	-	comment:P0DI81,P0DI82	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P08243	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P08237	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-514788|uniprotkb:Q16814|uniprotkb:Q16815|uniprotkb:J3KNX3|uniprotkb:Q6ZTT1|ensembl:ENSP00000309438|ensembl:ENSP00000352842|ensembl:ENSP00000446945|ensembl:ENSP00000448253|ensembl:ENSP00000449426|ensembl:ENSP00000450369	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:pfkam_human(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:PFKM(gene name)|psi-mi:PFKM(display_short)|uniprotkb:6-phosphofructokinase type A(gene name synonym)|uniprotkb:PFKX(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_000280.1|refseq:NP_001160158.1|refseq:NP_001160159.1|refseq:NP_001160160.1|refseq:XP_016874957.1|refseq:XP_005269034.1|refseq:XP_005269035.1|refseq:XP_005269036.1|refseq:XP_011536790.1|ensembl:ENSG00000152556(gene)|ensembl:ENST00000312352(transcript)|ensembl:ENST00000359794(transcript)|ensembl:ENST00000547587(transcript)|ensembl:ENST00000550345(transcript)|ensembl:ENST00000550924(transcript)|ensembl:ENST00000551339(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P08237|rcsb pdb:4OMT|reactome:R-HSA-70171	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:tB7V3jdmnyITZLPqyAYjrTWo/UE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:P06493	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O95831	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O95163	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O94826	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O94822	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O94776	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O76003	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O75306	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O75155	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O60762	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O43852	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O43837	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O43617	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O14744	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O14579	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:O00425	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:H3BUK6	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258457|ensembl:ENSP00000457684	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:h3buk6_human(display_long)|uniprotkb:TRAPPC2L(gene name)|psi-mi:TRAPPC2L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENST00000567895(transcript)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|interpro:IPR044760|ensembl:ENSG00000167515(gene)|refseq:NP_001305459.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Q4FqIrCePm+/nvYdyDjHAWS74h89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:H0YBR0	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258449|ensembl:ENSP00000430116	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:h0ybr0_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000167632(gene)|ensembl:ENST00000520857(transcript)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR013935(Transport protein Trs120)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:DZZ9H+4yRuKsklB44H7aWvCrwR09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:E9PHT6	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258434|ensembl:ENSP00000421433|ensembl:ENSP00000486414|uniprotkb:A0A0G2JR38	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:e9pht6_human(display_long)|uniprotkb:PANK4(gene name)|psi-mi:PANK4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000157881(gene)|ensembl:ENSG00000273494(gene)|ensembl:ENST00000435556(transcript)|ensembl:ENST00000630982(transcript)|go:"GO:0004594"(pantothenate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002791(Protein of unknown function DUF89)|interpro:IPR004567(Eukaryotic pantothenate kinase)|interpro:IPR015844(Pantothenate kinase, acetyl-CoA regulated, two-domain type)|interpro:IPR035073|interpro:IPR036075|interpro:IPR043129	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:+/kJ1VQEJL3GZ5vmhaEGIsV3cO49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:E1NZA1	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258417	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:C9J4M6	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:C9J3G2	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258380|ensembl:ENSP00000411906	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:c9j3g2_human(display_long)|uniprotkb:CBWD2(gene name)|psi-mi:CBWD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000136682(gene)|ensembl:ENST00000416503(transcript)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR011629("Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal")|interpro:IPR027417|refseq:NP_001317265.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:9f5T8EGHV6enn32Ama7MzQFNxGo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:B2RWN5	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-21258368	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:A8MXV4	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-11350801|ensembl:ENSP00000380251	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:nud19_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 19(gene name synonym)|uniprotkb:NUDT19(gene name)|psi-mi:NUDT19(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	refseq:NP_001099040.1|ensembl:ENSG00000213965(gene)|ensembl:ENST00000397061(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0010945"(CoA pyrophosphatase activity)|go:"GO:0015938"(coenzyme A catabolic process)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0044580"(butyryl-CoA catabolic process)|go:"GO:1901289"(succinyl-CoA catabolic process)|go:"GO:1902858"(propionyl-CoA metabolic process)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR039121|reactome:R-HSA-390918|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:nSyCFhGmUMc1wbmmLp6RZvUojaM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:A3KMH1	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BZR8	uniprotkb:A0A087WZT3	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-12006120|ensembl:ENSP00000306752|ensembl:ENSP00000482868	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:a0a087wzt3_human(display_long)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258469|imex:IM-26691-161	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000305321(transcript)|ensembl:ENST00000380596(transcript)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:XP_016855107.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/07/08	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:rW/b1xR3prAOe+MsPM8GgNgqqg49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20749	uniprotkb:Q92598	intact:EBI-958997|ensembl:ENSP00000164227	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:bcl3_human(display_long)|uniprotkb:BCL3(gene name)|psi-mi:BCL3(display_short)|uniprotkb:BCL4(gene name synonym)|uniprotkb:D19S37(gene name synonym)|uniprotkb:Proto-oncogene BCL3(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258808|imex:IM-26691-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005169.2|ensembl:ENSG00000069399(gene)|ensembl:ENST00000164227(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P20749|rcsb pdb:1K1A|rcsb pdb:1K1B	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:VqvziEG5TBZUct1eoVx6AoHRjhQ9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:TBhYFPpGM/UQlNrJXsiZIPSezbI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20749	uniprotkb:Q00653	intact:EBI-958997|ensembl:ENSP00000164227	intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9	psi-mi:bcl3_human(display_long)|uniprotkb:BCL3(gene name)|psi-mi:BCL3(display_short)|uniprotkb:BCL4(gene name synonym)|uniprotkb:D19S37(gene name synonym)|uniprotkb:Proto-oncogene BCL3(gene name synonym)	psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258808|imex:IM-26691-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005169.2|ensembl:ENSG00000069399(gene)|ensembl:ENST00000164227(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P20749|rcsb pdb:1K1A|rcsb pdb:1K1B	refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:VqvziEG5TBZUct1eoVx6AoHRjhQ9606	rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606	rigid:TBhYFPpGM/UQlNrJXsiZIPSezbI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20749	uniprotkb:P19838	intact:EBI-958997|ensembl:ENSP00000164227	intact:EBI-300010|ensembl:ENSP00000378297|ensembl:ENSP00000424790|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:bcl3_human(display_long)|uniprotkb:BCL3(gene name)|psi-mi:BCL3(display_short)|uniprotkb:BCL4(gene name synonym)|uniprotkb:D19S37(gene name synonym)|uniprotkb:Proto-oncogene BCL3(gene name synonym)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258808|imex:IM-26691-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005169.2|ensembl:ENSG00000069399(gene)|ensembl:ENST00000164227(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P20749|rcsb pdb:1K1A|rcsb pdb:1K1B	reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-448706|ensembl:ENSG00000109320(gene)|ensembl:ENST00000394820(transcript)|ensembl:ENST00000505458(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|refseq:NP_001158884.1|refseq:NP_003989.2|refseq:NP_001306155.1|dip:DIP-106N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:VqvziEG5TBZUct1eoVx6AoHRjhQ9606	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rigid:TBhYFPpGM/UQlNrJXsiZIPSezbI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20749	uniprotkb:P17066	intact:EBI-958997|ensembl:ENSP00000164227	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:bcl3_human(display_long)|uniprotkb:BCL3(gene name)|psi-mi:BCL3(display_short)|uniprotkb:BCL4(gene name synonym)|uniprotkb:D19S37(gene name synonym)|uniprotkb:Proto-oncogene BCL3(gene name synonym)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258808|imex:IM-26691-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005169.2|ensembl:ENSG00000069399(gene)|ensembl:ENST00000164227(transcript)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002467"(germinal center formation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010225"(response to UV-C)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030496"(midbody)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032996"(Bcl3-Bcl10 complex)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P20749|rcsb pdb:1K1A|rcsb pdb:1K1B	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:VqvziEG5TBZUct1eoVx6AoHRjhQ9606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	rigid:TBhYFPpGM/UQlNrJXsiZIPSezbI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q10589	uniprotkb:Q92643	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258826|imex:IM-26691-163	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:8qPc3JttkKuGusBr6eYRS0XBJr8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q10589	uniprotkb:Q969N2	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258826|imex:IM-26691-163	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:8qPc3JttkKuGusBr6eYRS0XBJr8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q10589	uniprotkb:O75348	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	intact:EBI-711802|intact:EBI-749668|uniprotkb:Q6IB33|ensembl:ENSP00000363162	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:vatg1_human(display_long)|uniprotkb:Vacuolar proton pump subunit G 1(gene name synonym)|uniprotkb:V-ATPase 13 kDa subunit 1(gene name synonym)|uniprotkb:Vacuolar proton pump subunit M16(gene name synonym)|uniprotkb:ATP6V1G1(gene name)|psi-mi:ATP6V1G1(display_short)|uniprotkb:ATP6G(gene name synonym)|uniprotkb:ATP6G1(gene name synonym)|uniprotkb:ATP6J(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258826|imex:IM-26691-163	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	refseq:NP_004879.1|ensembl:ENSG00000136888(gene)|ensembl:ENST00000374050(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|mint:O75348|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rogid:zsDN5vJcHlTb50mmly17mGztBAM9606	rigid:8qPc3JttkKuGusBr6eYRS0XBJr8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q10589	uniprotkb:O60762	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258826|imex:IM-26691-163	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	rigid:8qPc3JttkKuGusBr6eYRS0XBJr8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13363	uniprotkb:P55210	intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921	intact:EBI-523958|uniprotkb:B5BU45|uniprotkb:Q5SVL3|uniprotkb:Q13364|uniprotkb:Q96BA0|uniprotkb:Q5SVL0|uniprotkb:Q53YD5|ensembl:ENSP00000298701|ensembl:ENSP00000358321|ensembl:ENSP00000358324|ensembl:ENSP00000480584|uniprotkb:D3DRB8|uniprotkb:B4DQU7	psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym)	psi-mi:casp7_human(display_long)|uniprotkb:ICE-like apoptotic protease 3(gene name synonym)|uniprotkb:Apoptotic protease Mch-3(gene name synonym)|uniprotkb:CMH-1(gene name synonym)|uniprotkb:CASP7(gene name)|psi-mi:CASP7(display_short)|uniprotkb:MCH3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258844|imex:IM-26691-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700	refseq:NP_001218.1|refseq:NP_203124.1|refseq:NP_203125.1|refseq:NP_203126.1|ensembl:ENSG00000165806(gene)|ensembl:ENST00000345633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|ensembl:ENST00000369315(transcript)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009411"(response to UV)|go:"GO:0016485"(protein processing)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015471(Caspase-7)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P55210|rcsb pdb:1F1J|ensembl:ENST00000369318(transcript)|rcsb pdb:1GQF|ensembl:ENST00000621345(transcript)|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1K86|rcsb pdb:1K88|rcsb pdb:1KMC|rcsb pdb:1MIA|rcsb pdb:1SHJ|go:"GO:0004190"(aspartic-type endopeptidase activity)|rcsb pdb:1SHL|rcsb pdb:2QL5|go:"GO:0004197"(cysteine-type endopeptidase activity)|rcsb pdb:2QL7|go:"GO:0005634"(nucleus)|rcsb pdb:2QL9|rcsb pdb:2QLB|rcsb pdb:2QLF|rcsb pdb:2QLJ|rcsb pdb:3EDR|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3H1P|rcsb pdb:3IBC|rcsb pdb:3IBF|rcsb pdb:3R5K|rcsb pdb:4FDL|rcsb pdb:4FEA|rcsb pdb:4HQ0|rcsb pdb:4HQR|rcsb pdb:4JB8|reactome:R-HSA-111464|reactome:R-HSA-111465|reactome:R-HSA-111469|reactome:R-HSA-264870|rcsb pdb:4JJ8|rcsb pdb:4JR1|rcsb pdb:4JR2|rcsb pdb:4LSZ|rcsb pdb:4ZVO|rcsb pdb:4ZVP|rcsb pdb:4ZVQ|rcsb pdb:4ZVR|rcsb pdb:4ZVS|rcsb pdb:4ZVT|rcsb pdb:4ZVU|rcsb pdb:5IC6|rcsb pdb:5K20|rcsb pdb:5V6U|rcsb pdb:5V6Z|reactome:R-HSA-111459|reactome:R-HSA-111463|refseq:NP_001253986.1|refseq:NP_001253987.1|refseq:NP_001253985.1|refseq:NP_001307840.1|dip:DIP-29973N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606	rogid:XcSWtfWWnuOKIbAR+TXpkCq5fig9606	rigid:vLc8Eb5CdDGoIeldZloWMFihaXE	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q8IXI1	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q7Z6Z7	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9Y678	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9Y520	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055987.2|refseq:XP_006711301.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|ensembl:ENST00000338920|ensembl:ENSP00000343629|ensembl:ENSG00000117523|ensembl:ENST00000426496|ensembl:ENSP00000410219|ensembl:ENST00000647382|ensembl:ENSP00000495867|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9Y262	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UPN7	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UI10	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UDY2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1042602|uniprotkb:Q15883|uniprotkb:Q5VXL0|uniprotkb:Q8N756|uniprotkb:Q8NI14|uniprotkb:Q99839|uniprotkb:Q9UDY0|uniprotkb:Q9UDY1|uniprotkb:A2A3H9|uniprotkb:Q5VXL1|intact:EBI-10989219|ensembl:ENSP00000366453|uniprotkb:B7Z2R8|uniprotkb:B7Z7T6|uniprotkb:F5H301|uniprotkb:F5H886	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:zo2_human(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:ZO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001163886.1|refseq:NP_001163887.1|refseq:NP_004808.2|refseq:XP_011517508.1|refseq:XP_011517509.1|refseq:XP_011517510.1|refseq:XP_011517511.1|ensembl:ENSG00000119139(gene)|ensembl:ENST00000377245(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035598|interpro:IPR036028|interpro:IPR036034|mint:Q9UDY2|rcsb pdb:2OSG|rcsb pdb:3E17|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:iN/EF8QWKtekoj5eON764eKAdpg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UBS4	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UBQ5	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9UBF2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9NXW2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9NR50	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9H446	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-748952|uniprotkb:Q9Y313|uniprotkb:Q9Y6B3|uniprotkb:A8K3W2|uniprotkb:A8MT24|ensembl:ENSP00000420357	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rwdd1_human(display_long)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:RWDD1(gene name)|psi-mi:RWDD1(display_short)|uniprotkb:CGI-24(orf name)|uniprotkb:PTD013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_057036.2|refseq:NP_001007465.1|refseq:NP_057188.2|ensembl:ENST00000466444(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005844"(polysome)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|ensembl:ENSG00000111832(gene)|interpro:IPR040213|rcsb pdb:2EBM|interpro:IPR032378|dip:DIP-34520N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:OvfJFwoLwchgGBS56iOdvVs0TDg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q9BQE3	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q99613	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q96CP6	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1384139|uniprotkb:A6NKY7|uniprotkb:Q8NC77|uniprotkb:Q9P1Z5|ensembl:ENSP00000441032	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:astra_human(display_long)|uniprotkb:GRAMD1A(gene name)|psi-mi:GRAMD1A(display_short)|uniprotkb:KIAA1533(gene name synonym)|uniprotkb:GRAM domain-containing protein 1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001306964.1|refseq:NP_001129671.1|refseq:NP_065946.2|refseq:NP_001306963.1|refseq:NP_001306965.1|ensembl:ENSG00000089351(gene)|ensembl:ENST00000317991(transcript)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|mint:Q96CP6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:S7fzTVbf+LB0tpV7JvPZzpcs8709606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q969Z0	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q93008	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q8N9N2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-10268317|uniprotkb:Q9Y307|uniprotkb:Q5SW06|uniprotkb:Q5SW07|uniprotkb:Q96EI8|ensembl:ENSP00000339404|ensembl:ENSP00000378373	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ascc1_human(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001185727.1|refseq:NP_001185728.1|refseq:NP_001185729.1|ensembl:ENSG00000138303(gene)|ensembl:ENST00000342444(transcript)|ensembl:ENST00000394915(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR004088(K Homology, type 1)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR009210(Predicted eukaryotic LigT)|interpro:IPR019510|interpro:IPR036612|reactome:R-HSA-112126|refseq:XP_006717936.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:WfbfIpzdDj8dd1Ez1PbcIy2tnSA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q8N3C0	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q8IY21	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q5T4S7	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q5JSZ5	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q5H9R7	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q53EL6	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-935824|uniprotkb:O15501|uniprotkb:Q5VZS6|uniprotkb:Q6PJI5|uniprotkb:Q8TAR5|uniprotkb:Q99834|intact:EBI-2514227|uniprotkb:B2RCV4|uniprotkb:B5ME91|ensembl:ENSP00000280154	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pdcd4_human(display_long)|uniprotkb:PDCD4(gene name)|psi-mi:PDCD4(display_short)|uniprotkb:H731(gene name synonym)|uniprotkb:Nuclear antigen H731-like(gene name synonym)|uniprotkb:Neoplastic transformation inhibitor protein(gene name synonym)|uniprotkb:Protein 197/15a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055271.2|refseq:NP_663314.1|dip:DIP-29756N|ensembl:ENSG00000150593(gene)|ensembl:ENST00000280154(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|rcsb pdb:2GGF|rcsb pdb:2KZT|rcsb pdb:2RG8|rcsb pdb:2ZU6|rcsb pdb:3EIJ|reactome:R-HSA-8950505	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:kkqDk2CCFvHpSCKNDzV4wqSm1HE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q15386	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q15293	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q15021	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q15008	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q14974	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q14697	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-348004|ensembl:ENSP00000349053|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000089597(gene)|ensembl:ENST00000356638(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q14697|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9694548|reactome:R-HSA-9683686|refseq:NP_938148.1|refseq:NP_938149.2|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q14318	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q14152	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	intact:EBI-20649665	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	-	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:tuba3c_tuba3d_human(display_short)|psi-mi:EBI-20649665(display_long)|intact:TUBA3C/TUBA3D(author assigned name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	uniprotkb:P0DPH7(set member)|uniprotkb:P0DPH8(set member)|uniprotkb:Q13748(see-also)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q13576	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q13442	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q13347	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:fogC6nSNmIynV2ziHZboT9laA3M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q13144	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q13112	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q12789	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-357956|uniprotkb:B2RP21|uniprotkb:Q12838|uniprotkb:Q6DKN9|uniprotkb:Q9Y4W9|ensembl:ENSP00000348510	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:tf3c1_human(display_long)|uniprotkb:GTF3C1(gene name)|psi-mi:GTF3C1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001511.2|refseq:NP_001273171.1|dip:DIP-38212N|ensembl:ENSG00000077235(gene)|ensembl:ENST00000356183(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009304"(tRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q12789|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:1celgxr5g9oKbPr0x1SvI6S7hNE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:Q04637	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P78347	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P78344	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P63104	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P62304	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P62258	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P60842	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P60228	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P57678	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P55884	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P55084	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P53621	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P53618	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P52429	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P49458	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P48634	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSP00000372956|ensembl:ENSP00000387477|ensembl:ENSP00000387910|ensembl:ENSP00000396812|ensembl:ENSP00000400540|ensembl:ENSP00000404619|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000413977|ensembl:ENSP00000415182|ensembl:ENSP00000415363	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSP00000372956|ensembl:ENSP00000404619|ensembl:ENSP00000415182|ensembl:ENSP00000415363|ensembl:ENSP00000387910|ensembl:ENSP00000413977|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000400540|ensembl:ENSP00000387477|ensembl:ENSP00000396812|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSG00000204469(gene)|ensembl:ENSG00000206427(gene)|ensembl:ENSG00000225164(gene)|ensembl:ENSG00000225748(gene)|ensembl:ENSG00000226618(gene)|ensembl:ENSG00000231370(gene)|ensembl:ENSG00000231825(gene)|ensembl:ENST00000376007(transcript)|ensembl:ENST00000376033(transcript)|ensembl:ENST00000383455(transcript)|ensembl:ENST00000383464(transcript)|ensembl:ENST00000414956(transcript)|ensembl:ENST00000416335(transcript)|ensembl:ENST00000422962(transcript)|ensembl:ENST00000428775(transcript)|ensembl:ENST00000430737(transcript)|ensembl:ENST00000432252(transcript)|ensembl:ENST00000435971(transcript)|ensembl:ENST00000439762(transcript)|ensembl:ENST00000454306(transcript)|ensembl:ENST00000458561(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P48444	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P46821	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P42695	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P42345	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P41091	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001406.1|ensembl:ENSG00000130741(gene)|ensembl:ENST00000253039(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR044127|interpro:IPR044128|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P40939	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P35998	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P35606	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P31946	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P29144	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1044672|uniprotkb:Q5VZU8|ensembl:ENSP00000365233	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:tpp2_human(display_long)|uniprotkb:Tripeptidyl-peptidase II(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:TPP2(gene name)|psi-mi:TPP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003282.2|ensembl:ENSG00000134900(gene)|ensembl:ENST00000376065(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022229|interpro:IPR022398|interpro:IPR023828|interpro:IPR034051|interpro:IPR036852|mint:P29144|reactome:R-HSA-983168|refseq:NP_001317517.1|dip:DIP-50761N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:I+B6XApXumvX26aR5AdMhkhZVc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P27824	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P27348	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P19388	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P12004	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P08243	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P05198	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:P04440	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2802503|uniprotkb:Q9GIM2|uniprotkb:Q5EP47|uniprotkb:Q29682|uniprotkb:Q29879|uniprotkb:B8ZX68|uniprotkb:Q5EP52|uniprotkb:Q29698|uniprotkb:Q29827|uniprotkb:Q5EP46|uniprotkb:Q9XS11|uniprotkb:Q14279|uniprotkb:Q5YLA6|uniprotkb:O19700|uniprotkb:P01916|uniprotkb:B9W5S8|uniprotkb:O98219|uniprotkb:Q29778|uniprotkb:B9W6F9|uniprotkb:O19749|uniprotkb:Q30033|uniprotkb:Q5EP53|uniprotkb:Q9TQE2|uniprotkb:Q9GJ41|uniprotkb:Q29684|uniprotkb:O00259|uniprotkb:Q5I4H9|uniprotkb:A8YPB3|uniprotkb:P04232|uniprotkb:Q5ENE1|uniprotkb:C0MPP5|uniprotkb:Q30174|uniprotkb:Q29880|uniprotkb:Q8HWT5|uniprotkb:Q30052|uniprotkb:Q9TNT7|uniprotkb:Q5SQ73|uniprotkb:Q9BD13|uniprotkb:Q5EP51|uniprotkb:Q4JHD8|uniprotkb:Q860Z7|uniprotkb:Q5ENW3|uniprotkb:A0PFJ7|uniprotkb:Q6LBX3|uniprotkb:Q6LBX7|uniprotkb:B7VF87|uniprotkb:C0MPQ7|uniprotkb:Q30032|uniprotkb:Q9MY67|uniprotkb:Q5ISH4|uniprotkb:Q9XS12|uniprotkb:Q29977|uniprotkb:Q6PWX6|uniprotkb:Q30053|uniprotkb:Q0ZFN3|uniprotkb:Q5EP56|uniprotkb:Q27S71|uniprotkb:Q30050|uniprotkb:P79493|uniprotkb:P79608|uniprotkb:Q6LBX6|uniprotkb:Q0P0L4|uniprotkb:Q6IVX1|uniprotkb:Q30051|uniprotkb:O98216|uniprotkb:A5I886|uniprotkb:Q95IT7|uniprotkb:O98217|uniprotkb:Q29714|uniprotkb:O19698|uniprotkb:B5U8B4|uniprotkb:C5IZL1|uniprotkb:Q4GY31|uniprotkb:Q29775|uniprotkb:Q30054|uniprotkb:B7VF80|uniprotkb:O98215|uniprotkb:B8ZYT0|uniprotkb:Q30055|uniprotkb:Q29776|uniprotkb:C0MPQ5|uniprotkb:Q5STP2|uniprotkb:Q95IT8|uniprotkb:C0MPQ3|uniprotkb:Q6LBX2|uniprotkb:O98223|uniprotkb:C0MPQ6|uniprotkb:Q30034|uniprotkb:O46884|uniprotkb:Q29779|uniprotkb:Q6LBX4|uniprotkb:Q5ISH5|uniprotkb:C0MPQ2|uniprotkb:O19702|uniprotkb:Q8HWL7|uniprotkb:Q9GIX6|uniprotkb:Q29898|uniprotkb:Q2MGW3|uniprotkb:Q6TAS4|uniprotkb:O98218|uniprotkb:Q8SNC4|uniprotkb:Q29828|uniprotkb:Q9GIM4|uniprotkb:O77952|uniprotkb:Q7YQ10|uniprotkb:Q5EP49|uniprotkb:Q714U1|uniprotkb:Q6LBX5|uniprotkb:Q5I4H8|uniprotkb:B9W6F7|uniprotkb:Q95HC1|uniprotkb:P13763|uniprotkb:C4R9J5|uniprotkb:Q5ENE0|uniprotkb:Q30015|uniprotkb:Q30031|uniprotkb:Q29781|uniprotkb:O98222|uniprotkb:Q714U2|ensembl:ENSP00000382422|ensembl:ENSP00000389288|ensembl:ENSP00000396095|ensembl:ENSP00000407674|ensembl:ENSP00000408146|ensembl:ENSP00000414196	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:dpb1_human(display_long)|uniprotkb:HLA-DP1B(gene name synonym)|uniprotkb:"HLA class II histocompatibility antigen, DP(W4) beta chain"(gene name synonym)|uniprotkb:MHC class II antigen DPB1(gene name synonym)|uniprotkb:HLA-DPB1(gene name)|psi-mi:HLA-DPB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_002112.3|ensembl:ENSG00000215048(gene)|ensembl:ENSG00000223865(gene)|ensembl:ENSG00000226826(gene)|ensembl:ENSG00000230763(gene)|ensembl:ENSG00000236693(gene)|ensembl:ENSG00000237710(gene)|ensembl:ENST00000399500(transcript)|ensembl:ENST00000411749(transcript)|ensembl:ENST00000418931(transcript)|ensembl:ENST00000425130(transcript)|ensembl:ENST00000433800(transcript)|ensembl:ENST00000454006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:3LQZ|rcsb pdb:4P4K|rcsb pdb:4P4R|rcsb pdb:4P57|rcsb pdb:4P5K|rcsb pdb:4P5M|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:gy8rTenPR8u64fM9Kzl7ocoX3CM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O95470	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O95071	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O94829	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O94822	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O75822	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O60739	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000114784(gene)|ensembl:ENST00000232905(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|refseq:NP_005866.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O43823	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1237481|ensembl:ENSP00000269701	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O43242	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O15372	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-709735|ensembl:ENSP00000429931	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O15371	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O15173	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O15084	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O14802	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O14617	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003929.4|refseq:NP_001248755.1|ensembl:ENSG00000065000(gene)|ensembl:ENST00000345016(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|dip:DIP-46793N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O14602	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-286439|uniprotkb:Q9BS77|ensembl:ENSP00000354722	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:if1ay_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:EIF1AY(gene name)|psi-mi:EIF1AY(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_004672.2|refseq:NP_001265541.1|ensembl:ENSG00000198692(gene)|ensembl:ENST00000361365(transcript)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:8nbys9cgdyGlFgYev/Ws9Q0cu6s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O14579	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O00743	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O00303	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:O00264	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:M0QYT0	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-12502729|ensembl:ENSP00000470059	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:m0qyt0_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000268083(gene)|ensembl:ENST00000594769(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001753(Crotonase, core)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029045|interpro:IPR034816|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:5AdJb7A6Ayo1STGOHBl+RTKwZ6c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:K7EL20	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258967|ensembl:ENSP00000465882	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:k7el20_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000130811(gene)|ensembl:ENST00000588709(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:uZXb01pYRdoP+H8dfr/QBc2/Txo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:I3L4P8	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:H6VRG2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258937	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:h6vrg2_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:Keratin, type II cytoskeletal 1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	go:"GO:0005886"(plasma membrane)|go:"GO:0045095"(keratin filament)|interpro:IPR018039|interpro:IPR039008|interpro:IPR032449|interpro:IPR032444|interpro:IPR003054(Type II keratin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:PLuY4SY5eKZ1V/E2+/aEfMHIF9s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:H0YCQ8	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258927|ensembl:ENSP00000432139	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:h0ycq8_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000149100(gene)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040750|ensembl:ENST00000526267(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:YKZM4oKZZ19CTTf2uGNjPgZ3eUQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:F8VUA7	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:F8VRU2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258900|ensembl:ENSP00000448398	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:f8vru2_human(display_long)|uniprotkb:POLR3B(gene name)|psi-mi:POLR3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000013503(gene)|ensembl:ENST00000549569(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:esKzrXTxcJPX5mzssaY7LrcLJUk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:C9JW96	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258889|ensembl:ENSP00000393320	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:c9jw96_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000167085(gene)|ensembl:ENST00000419140(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:m+QS9IeeD5UlWLw8/X1LBNGUqMQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:C9JI87	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258875|ensembl:ENSP00000390129	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:c9ji87_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000213585(gene)|ensembl:ENST00000425992(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:XQBT9gfVRbapMMX65dSqFGkk7p09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:C9J470	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258863|ensembl:ENSP00000405237	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:c9j470_human(display_long)|uniprotkb:NCAPH(gene name)|psi-mi:NCAPH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000121152(gene)|ensembl:ENST00000435975(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|interpro:IPR022816	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:lQwu9inrN64YhVd4Bvtoc9WEAOw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:B4DUJ2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-21258853	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:b4duj2_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	go:"GO:0016021"(integral component of membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0070206"(protein trimerization)|interpro:IPR022339|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR036613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Td0lKVcRDym9kBgN9wSzB6h3G0Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P04233	uniprotkb:A3KMH1	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21258980|imex:IM-26691-63	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P21926	uniprotkb:Q969P0	intact:EBI-4280101|uniprotkb:D3DUQ9|uniprotkb:Q5J7W6|uniprotkb:Q96ES4|ensembl:ENSP00000009180|ensembl:ENSP00000371958|ensembl:ENSP00000496639	intact:EBI-8293590|uniprotkb:Q96DP4|uniprotkb:Q9BTG9|intact:MINT-4536413|uniprotkb:Q8NG09|ensembl:ENSP00000316664|ensembl:ENSP00000357065|ensembl:ENSP00000477565	psi-mi:cd9_human(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:MIC3(gene name synonym)|uniprotkb:TSPAN29(gene name synonym)|uniprotkb:5H9 antigen(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 2 protein(gene name synonym)|uniprotkb:Leukocyte antigen MIC3(gene name synonym)|uniprotkb:Motility-related protein(gene name synonym)|uniprotkb:Tetraspanin-29(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:GIG2(orf name)	psi-mi:igsf8_human(display_long)|uniprotkb:IGSF8(gene name)|psi-mi:IGSF8(display_short)|uniprotkb:CD81P3(gene name synonym)|uniprotkb:EWI2(gene name synonym)|uniprotkb:KCT4(gene name synonym)|uniprotkb:Prostaglandin regulatory-like protein(gene name synonym)|uniprotkb:CD81 partner 3(gene name synonym)|uniprotkb:Glu-Trp-Ile EWI motif-containing protein 2(gene name synonym)|uniprotkb:Keratinocytes-associated transmembrane protein 4(gene name synonym)|uniprotkb:LIR-D1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259300|imex:IM-26691-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001760.1|ensembl:ENSG00000010278(gene)|ensembl:ENST00000009180(transcript)|ensembl:ENST00000382518(transcript)|ensembl:ENST00000538834(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|rcsb pdb:6K4J|rcsb pdb:6RLO|rcsb pdb:6RLR|rcsb pdb:6Z1V|rcsb pdb:6Z20|reactome:R-HSA-114608|reactome:R-HSA-1300645|reactome:R-HSA-5336415|refseq:NP_001317241.1|dip:DIP-1122N	refseq:XP_016858324.1|refseq:XP_016858325.1|refseq:XP_016858326.1|refseq:NP_001193594.1|refseq:NP_443100.1|refseq:NP_001307176.1|ensembl:ENSG00000162729(gene)|ensembl:ENST00000314485(transcript)|ensembl:ENST00000368086(transcript)|ensembl:ENST00000614243(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007338"(single fertilization)|go:"GO:0007399"(nervous system development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179	-	-	comment:mint|comment:homomint|function:"May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain"	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:3IurQcWENxQVeRwGfqL0Os8m81E9606	rogid:zLzcbQrgEvLHEXGb5FYlV8C3TFA9606	rigid:PtaYYnFUbueHzRsSV+VHIGaqoy8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P21926	uniprotkb:Q9P2B2	intact:EBI-4280101|uniprotkb:D3DUQ9|uniprotkb:Q5J7W6|uniprotkb:Q96ES4|ensembl:ENSP00000009180|ensembl:ENSP00000371958|ensembl:ENSP00000496639	intact:EBI-4290465|uniprotkb:Q5VVU9|uniprotkb:Q8N2K6|ensembl:ENSP00000376899	psi-mi:cd9_human(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:MIC3(gene name synonym)|uniprotkb:TSPAN29(gene name synonym)|uniprotkb:5H9 antigen(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 2 protein(gene name synonym)|uniprotkb:Leukocyte antigen MIC3(gene name synonym)|uniprotkb:Motility-related protein(gene name synonym)|uniprotkb:Tetraspanin-29(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:GIG2(orf name)	psi-mi:fprp_human(display_long)|uniprotkb:PTGFRN(gene name)|psi-mi:PTGFRN(display_short)|uniprotkb:CD9P1(gene name synonym)|uniprotkb:EWIF(gene name synonym)|uniprotkb:FPRP(gene name synonym)|uniprotkb:KIAA1436(gene name synonym)|uniprotkb:CD9 partner 1(gene name synonym)|uniprotkb:Glu-Trp-Ile EWI motif-containing protein F(gene name synonym)|uniprotkb:Prostaglandin F2-alpha receptor regulatory protein(gene name synonym)|uniprotkb:Prostaglandin F2-alpha receptor-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259300|imex:IM-26691-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001760.1|ensembl:ENSG00000010278(gene)|ensembl:ENST00000009180(transcript)|ensembl:ENST00000382518(transcript)|ensembl:ENST00000538834(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|rcsb pdb:6K4J|rcsb pdb:6RLO|rcsb pdb:6RLR|rcsb pdb:6Z1V|rcsb pdb:6Z20|reactome:R-HSA-114608|reactome:R-HSA-1300645|reactome:R-HSA-5336415|refseq:NP_001317241.1|dip:DIP-1122N	ensembl:ENSG00000134247(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009986"(cell surface)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034389"(lipid droplet organization)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|ensembl:ENST00000393203(transcript)|refseq:NP_065173.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:3IurQcWENxQVeRwGfqL0Os8m81E9606	rogid:gb/QBCtFB6j/doesFGl/7+QX4Kc9606	rigid:PtaYYnFUbueHzRsSV+VHIGaqoy8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P21926	uniprotkb:Q9NPA3	intact:EBI-4280101|uniprotkb:D3DUQ9|uniprotkb:Q5J7W6|uniprotkb:Q96ES4|ensembl:ENSP00000009180|ensembl:ENSP00000371958|ensembl:ENSP00000496639	intact:EBI-750096|uniprotkb:D3DWB2|ensembl:ENSP00000338706|ensembl:ENSP00000367735|ensembl:ENSP00000416670|ensembl:ENSP00000483547	psi-mi:cd9_human(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:MIC3(gene name synonym)|uniprotkb:TSPAN29(gene name synonym)|uniprotkb:5H9 antigen(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 2 protein(gene name synonym)|uniprotkb:Leukocyte antigen MIC3(gene name synonym)|uniprotkb:Motility-related protein(gene name synonym)|uniprotkb:Tetraspanin-29(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:GIG2(orf name)	psi-mi:m1ip1_human(display_long)|uniprotkb:Gastrulation-specific G12-like protein(gene name synonym)|uniprotkb:Mid1-interacting G12-like protein(gene name synonym)|uniprotkb:Protein STRAIT11499(gene name synonym)|uniprotkb:MID1IP1(gene name)|psi-mi:MID1IP1(display_short)|uniprotkb:MIG12(gene name synonym)|uniprotkb:Spot 14-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259300|imex:IM-26691-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001760.1|ensembl:ENSG00000010278(gene)|ensembl:ENST00000009180(transcript)|ensembl:ENST00000382518(transcript)|ensembl:ENST00000538834(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|rcsb pdb:6K4J|rcsb pdb:6RLO|rcsb pdb:6RLR|rcsb pdb:6Z1V|rcsb pdb:6Z20|reactome:R-HSA-114608|reactome:R-HSA-1300645|reactome:R-HSA-5336415|refseq:NP_001317241.1|dip:DIP-1122N	refseq:NP_001092260.1|refseq:NP_001092261.1|refseq:NP_067065.1|ensembl:ENSG00000165175(gene)|ensembl:ENST00000336949(transcript)|ensembl:ENST00000378474(transcript)|ensembl:ENST00000457894(transcript)|ensembl:ENST00000614558(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0051258"(protein polymerization)|go:"GO:0051351"(positive regulation of ligase activity)|interpro:IPR009786(Thyroid hormone-inducible hepatic Spot 14)|mint:Q9NPA3|reactome:R-HSA-200425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:3IurQcWENxQVeRwGfqL0Os8m81E9606	rogid:kB3vPijNxsKIH/K5NXkj4BIzneA9606	rigid:PtaYYnFUbueHzRsSV+VHIGaqoy8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P21926	uniprotkb:Q96CP2	intact:EBI-4280101|uniprotkb:D3DUQ9|uniprotkb:Q5J7W6|uniprotkb:Q96ES4|ensembl:ENSP00000009180|ensembl:ENSP00000371958|ensembl:ENSP00000496639	intact:EBI-9394506|ensembl:ENSP00000293981|ensembl:ENSP00000380159	psi-mi:cd9_human(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:MIC3(gene name synonym)|uniprotkb:TSPAN29(gene name synonym)|uniprotkb:5H9 antigen(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 2 protein(gene name synonym)|uniprotkb:Leukocyte antigen MIC3(gene name synonym)|uniprotkb:Motility-related protein(gene name synonym)|uniprotkb:Tetraspanin-29(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:GIG2(orf name)	psi-mi:fwch2_human(display_long)|uniprotkb:FLYWCH2(gene name)|psi-mi:FLYWCH2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259300|imex:IM-26691-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001760.1|ensembl:ENSG00000010278(gene)|ensembl:ENST00000009180(transcript)|ensembl:ENST00000382518(transcript)|ensembl:ENST00000538834(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|rcsb pdb:6K4J|rcsb pdb:6RLO|rcsb pdb:6RLR|rcsb pdb:6Z1V|rcsb pdb:6Z20|reactome:R-HSA-114608|reactome:R-HSA-1300645|reactome:R-HSA-5336415|refseq:NP_001317241.1|dip:DIP-1122N	refseq:NP_001135971.1|refseq:NP_001135972.1|refseq:NP_612448.1|refseq:XP_005255135.1|ensembl:ENSG00000162076(gene)|ensembl:ENST00000293981(transcript)|ensembl:ENST00000396958(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR029279|interpro:IPR040312	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:3IurQcWENxQVeRwGfqL0Os8m81E9606	rogid:hFUp5nK4z8ENLRQK2GSYIqTFljg9606	rigid:PtaYYnFUbueHzRsSV+VHIGaqoy8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P14635	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q9UP83	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-389502|uniprotkb:A4D0R6|uniprotkb:A4D0R7|uniprotkb:Q6NUL5|uniprotkb:O14555|uniprotkb:O95008|ensembl:ENSP00000297135|ensembl:ENSP00000334703|ensembl:ENSP00000377228	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cog5_human(display_long)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001154992.1|refseq:NP_006339.3|refseq:NP_859422.2|ensembl:ENSG00000164597(gene)|ensembl:ENST00000297135(transcript)|ensembl:ENST00000347053(transcript)|ensembl:ENST00000393603(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR019465|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:Jytff1Ttr5vNSps1MeFz2ZoP1Kg9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q9UBI6	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-358636|uniprotkb:Q9BRV5|ensembl:ENSP00000360021|uniprotkb:Q69YP5	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:gbg12_human(display_long)|uniprotkb:GNG12(gene name)|psi-mi:GNG12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_061329.3|ensembl:ENSG00000172380(gene)|ensembl:ENST00000370982(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|refseq:XP_016857298.1|refseq:XP_016857299.1|refseq:XP_016857300.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:rCPylE+1WWtdSzfdOd61jXbvM9M9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q9H2D6	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q9BSJ8	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q6NYC8	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q15004	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-10971436|ensembl:ENSP00000300035|uniprotkb:A8K3Y3|uniprotkb:G9G694|uniprotkb:G9G696|uniprotkb:A6NNU5	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:paf15_human(display_long)|uniprotkb:PCLAF(gene name)|psi-mi:PCLAF(display_short)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 9(gene name synonym)|uniprotkb:KIAA0101(gene name synonym)|uniprotkb:NS5ATP9(gene name synonym)|uniprotkb:Overexpressed in anaplastic thyroid carcinoma 1(gene name synonym)|uniprotkb:PAF(gene name synonym)|uniprotkb:PCNA-associated factor of 15 kDa(gene name synonym)|uniprotkb:PCNA-clamp-associated factor(gene name synonym)|uniprotkb:L5(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001025160.1|refseq:NP_055551.1|ensembl:ENSG00000166803(gene)|ensembl:ENST00000300035(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007098"(centrosome cycle)|go:"GO:0009411"(response to UV)|go:"GO:0019985"(translesion synthesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR031444|interpro:IPR040444|rcsb pdb:4D2G|rcsb pdb:6EHT|rcsb pdb:6GWS|rcsb pdb:6IIW|reactome:R-HSA-5656169|go:"GO:0006260"(DNA replication)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:PuYmSApcLCyxazgAwPBJRzzJp7o9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q13309	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-456291|uniprotkb:Q8TDZ0|uniprotkb:Q8TDZ1|uniprotkb:Q9BV69|ensembl:ENSP00000274255|uniprotkb:A8K5E0|uniprotkb:B4DJT4	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:skp2_human(display_long)|uniprotkb:F-box protein Skp2(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p45(gene name synonym)|uniprotkb:p45skp2(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 1(gene name synonym)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)|uniprotkb:FBXL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	ensembl:ENSG00000145604(gene)|ensembl:ENST00000274255(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|rcsb pdb:2ASS|rcsb pdb:2AST|interpro:IPR032675|rcsb pdb:7B5L|interpro:IPR036047|mint:Q13309|rcsb pdb:1FQV|rcsb pdb:7B5M|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|refseq:NP_005974.2|refseq:NP_116026.1|refseq:NP_001230049.1|dip:DIP-17011N|rcsb pdb:7B5R|reactome:R-HSA-174178|reactome:R-HSA-187577|reactome:R-HSA-5689880|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9687136|reactome:R-HSA-9708530|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:VABxcX3qu0Yr6eRNYINqvAPhPMc9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q12834	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:Q00535	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-1041567|uniprotkb:A1XKG3|ensembl:ENSP00000419782	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cdk5_human(display_long)|uniprotkb:CDK5(gene name)|psi-mi:CDK5(display_short)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:CDKN5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001157882.1|refseq:NP_004926.1|ensembl:ENSG00000164885(gene)|ensembl:ENST00000485972(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048156"(tau protein binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q00535|rcsb pdb:1H4L|rcsb pdb:1LFR|rcsb pdb:1UNG|rcsb pdb:1UNH|rcsb pdb:1UNL|rcsb pdb:3O0G|rcsb pdb:4AU8|reactome:R-HSA-180024|reactome:R-HSA-399956|reactome:R-HSA-6804756|reactome:R-HSA-8862803|reactome:R-HSA-9031628|reactome:R-HSA-9032845|reactome:R-HSA-983231|dip:DIP-24221N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:NddS77Gpf0Gt5O3MPylAUfJ7QOE9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P61024	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-456371|uniprotkb:P33551|ensembl:ENSP00000311083	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cks1_human(display_long)|uniprotkb:PNAS-16(orf name)|uniprotkb:PNAS-143(orf name)|uniprotkb:CKS1B(gene name)|psi-mi:CKS1B(display_short)|uniprotkb:CKS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001817.1|dip:DIP-102N|rcsb pdb:4YC6|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-69231|ensembl:ENSG00000173207(gene)|ensembl:ENST00000308987(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|mint:P61024|rcsb pdb:1BUH|rcsb pdb:1DKS|rcsb pdb:1DKT|rcsb pdb:2ASS|rcsb pdb:2AST	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:ANoFqi0sBqFKOAyhcMhTWA9kghY9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P30281	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-375013|uniprotkb:Q5T8J0|uniprotkb:Q96F49|uniprotkb:B2RD63|uniprotkb:Q6FG62|ensembl:ENSP00000362082|uniprotkb:B3KQ22|uniprotkb:E9PAS4|uniprotkb:E9PB36|intact:EBI-10979075|intact:EBI-11132276	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ccnd3_human(display_long)|uniprotkb:CCND3(gene name)|psi-mi:CCND3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001129489.1|refseq:NP_001129597.1|refseq:NP_001129598.1|refseq:NP_001751.1|reactome:R-HSA-9661069|ensembl:ENSG00000112576(gene)|ensembl:ENST00000372991(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P30281|rcsb pdb:3G33|reactome:R-HSA-381340|reactome:R-HSA-5687128|reactome:R-HSA-69231|reactome:R-HSA-8934593|refseq:NP_001274356.1|refseq:NP_001274363.1|dip:DIP-31734N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:y9i4nI+f/p5JWQAOnSbKr/As7gQ9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P24941	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-375096|ensembl:ENSP00000266970|uniprotkb:A8K7C6|uniprotkb:O75100	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cdk2_human(display_long)|uniprotkb:CDK2(gene name)|psi-mi:CDK2(display_short)|uniprotkb:p33 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 2(gene name synonym)|uniprotkb:CDKN2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	ensembl:ENSG00000123374(gene)|ensembl:ENST00000266970(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090398"(cellular senescence)|go:"GO:0097123"(cyclin A1-CDK2 complex)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:0097135"(cyclin E2-CDK2 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P24941|rcsb pdb:1AQ1|rcsb pdb:1B39|rcsb pdb:1B38|rcsb pdb:1BUH|rcsb pdb:1CKP|rcsb pdb:1DI8|rcsb pdb:1DM2|rcsb pdb:1E1V|rcsb pdb:1E1X|rcsb pdb:1E9H|rcsb pdb:1F5Q|rcsb pdb:1FIN|rcsb pdb:1FQ1|rcsb pdb:1FVT|rcsb pdb:1FVV|rcsb pdb:1G5S|rcsb pdb:1GIH|rcsb pdb:1GII|rcsb pdb:1GIJ|rcsb pdb:1GY3|rcsb pdb:3R6X|rcsb pdb:3R71|rcsb pdb:3R73|rcsb pdb:3R7E|rcsb pdb:3R7I|rcsb pdb:3R7U|rcsb pdb:3R7V|rcsb pdb:3R7Y|rcsb pdb:3R83|rcsb pdb:3R8L|rcsb pdb:3R8M|rcsb pdb:3R8P|rcsb pdb:3R8U|rcsb pdb:3R8V|rcsb pdb:3R8Z|rcsb pdb:3R9D|rcsb pdb:3R9H|rcsb pdb:3R9N|rcsb pdb:3R9O|rcsb pdb:3RAH|rcsb pdb:3RAI|rcsb pdb:3RAK|rcsb pdb:3RAL|rcsb pdb:3RJC|refseq:NP_001789.2|refseq:NP_439892.2|rcsb pdb:1URC|rcsb pdb:1URW|rcsb pdb:1V1K|rcsb pdb:1VYW|rcsb pdb:1VYZ|rcsb pdb:1W0X|rcsb pdb:1W8C|rcsb pdb:1GZ8|rcsb pdb:1H00|rcsb pdb:1H01|rcsb pdb:1H07|rcsb pdb:1H08|rcsb pdb:1H0V|rcsb pdb:1H0W|rcsb pdb:1H1P|rcsb pdb:1H1Q|rcsb pdb:1H1R|rcsb pdb:1H1S|rcsb pdb:1H24|rcsb pdb:1H25|rcsb pdb:1H26|rcsb pdb:1H27|rcsb pdb:1H28|rcsb pdb:1HCK|rcsb pdb:1HCL|rcsb pdb:1JST|rcsb pdb:1JSU|rcsb pdb:1JSV|rcsb pdb:1JVP|rcsb pdb:1KE5|rcsb pdb:1KE6|rcsb pdb:1KE7|rcsb pdb:1KE8|rcsb pdb:1KE9|rcsb pdb:1OGU|rcsb pdb:1OI9|rcsb pdb:1OIQ|rcsb pdb:1OIR|rcsb pdb:1OIT|rcsb pdb:1OIU|rcsb pdb:1OIY|rcsb pdb:1OKV|rcsb pdb:1OKW|rcsb pdb:1OL1|rcsb pdb:1OL2|rcsb pdb:1P2A|rcsb pdb:1P5E|rcsb pdb:1PF8|rcsb pdb:1PKD|rcsb pdb:1PW2|rcsb pdb:1PXI|rcsb pdb:1PXJ|rcsb pdb:1PXK|rcsb pdb:1PXL|rcsb pdb:1PXM|rcsb pdb:1PXN|rcsb pdb:1PXO|rcsb pdb:1PXP|rcsb pdb:1PYE|rcsb pdb:1QMZ|rcsb pdb:1R78|rcsb pdb:1W98|rcsb pdb:1WCC|rcsb pdb:1Y8Y|rcsb pdb:1Y91|rcsb pdb:1YKR|rcsb pdb:2A0C|rcsb pdb:2A4L|rcsb pdb:2B52|rcsb pdb:2B53|rcsb pdb:2B54|rcsb pdb:2B55|rcsb pdb:2BHE|rcsb pdb:2BHH|rcsb pdb:2BKZ|rcsb pdb:2BPM|rcsb pdb:2BTR|rcsb pdb:2BTS|rcsb pdb:2C4G|rcsb pdb:2C5N|rcsb pdb:2C5O|rcsb pdb:2C5V|rcsb pdb:2C5X|rcsb pdb:2C5Y|rcsb pdb:2C68|rcsb pdb:2C69|rcsb pdb:2C6I|rcsb pdb:2C6K|rcsb pdb:2C6L|rcsb pdb:2C6M|rcsb pdb:2C6O|rcsb pdb:2C6T|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:3BHT|rcsb pdb:2CJM|rcsb pdb:2CLX|rcsb pdb:2DS1|rcsb pdb:2DUV|rcsb pdb:2EXM|rcsb pdb:2FVD|rcsb pdb:2G9X|rcsb pdb:2HIC|rcsb pdb:2I40|rcsb pdb:2IW6|rcsb pdb:2IW8|rcsb pdb:2IW9|rcsb pdb:2J9M|rcsb pdb:2JGZ|rcsb pdb:2R3F|rcsb pdb:2R3G|rcsb pdb:2R3H|rcsb pdb:2R3I|rcsb pdb:2R3J|rcsb pdb:2R3K|rcsb pdb:2R3L|rcsb pdb:2R3M|rcsb pdb:2R3N|rcsb pdb:2R3O|rcsb pdb:2R3P|rcsb pdb:2R3Q|rcsb pdb:2R3R|rcsb pdb:2R64|rcsb pdb:2UUE|rcsb pdb:2UZB|rcsb pdb:2UZD|rcsb pdb:2UZE|rcsb pdb:2UZL|rcsb pdb:2UZN|rcsb pdb:2UZO|rcsb pdb:2V0D|rcsb pdb:2V22|rcsb pdb:2VTA|rcsb pdb:2VTH|rcsb pdb:2VTI|rcsb pdb:2VTJ|rcsb pdb:2VTL|rcsb pdb:2VTM|rcsb pdb:2VTN|rcsb pdb:2VTO|rcsb pdb:2VTP|rcsb pdb:2VTQ|rcsb pdb:2VTR|rcsb pdb:2VTS|rcsb pdb:2VTT|rcsb pdb:2VU3|rcsb pdb:2VV9|rcsb pdb:2W05|rcsb pdb:2W06|rcsb pdb:2W17|rcsb pdb:2W1H|rcsb pdb:2WEV|rcsb pdb:2WFY|rcsb pdb:2WHB|rcsb pdb:2WIH|rcsb pdb:2WIP|rcsb pdb:2WMA|rcsb pdb:2WMB|rcsb pdb:2WPA|rcsb pdb:2WXV|rcsb pdb:2X1N|rcsb pdb:2XMY|rcsb pdb:2XNB|rcsb pdb:3BHU|rcsb pdb:3BHV|rcsb pdb:3DDP|rcsb pdb:3DDQ|rcsb pdb:3DOG|rcsb pdb:3EID|rcsb pdb:3EJ1|rcsb pdb:3EOC|rcsb pdb:3EZR|rcsb pdb:3EZV|rcsb pdb:3F5X|rcsb pdb:3FZ1|rcsb pdb:3IG7|rcsb pdb:3IGG|rcsb pdb:3LE6|rcsb pdb:3LFN|rcsb pdb:3LFQ|rcsb pdb:3LFS|rcsb pdb:3MY5|rcsb pdb:3NS9|rcsb pdb:3PJ8|rcsb pdb:3PXF|rcsb pdb:3PXQ|rcsb pdb:3PXR|rcsb pdb:3PXY|rcsb pdb:3PXZ|rcsb pdb:3PY0|rcsb pdb:3PY1|rcsb pdb:3QHR|rcsb pdb:3QHW|rcsb pdb:3QL8|rcsb pdb:3QQF|rcsb pdb:3QQG|rcsb pdb:3QQH|rcsb pdb:3QQJ|rcsb pdb:3QQK|rcsb pdb:3QQL|rcsb pdb:3QRT|rcsb pdb:3QRU|rcsb pdb:3QTQ|rcsb pdb:3QTR|rcsb pdb:3QTS|rcsb pdb:3QTU|rcsb pdb:3QTW|rcsb pdb:3QTX|rcsb pdb:3QTZ|rcsb pdb:3QU0|rcsb pdb:3QWJ|rcsb pdb:3QWK|rcsb pdb:3QX2|rcsb pdb:3QX4|rcsb pdb:3QXO|rcsb pdb:3QXP|rcsb pdb:3QZF|rcsb pdb:3QZG|rcsb pdb:3QZH|rcsb pdb:3QZI|rcsb pdb:3R1Q|rcsb pdb:3R1S|rcsb pdb:3R1Y|rcsb pdb:3R28|refseq:NP_001277159.1|rcsb pdb:3RK5|rcsb pdb:3RK7|rcsb pdb:3RK9|rcsb pdb:3RKB|rcsb pdb:3RM6|rcsb pdb:3RM7|rcsb pdb:3RMF|rcsb pdb:3RNI|rcsb pdb:3ROY|rcsb pdb:3RPO|rcsb pdb:3RPR|rcsb pdb:3RPV|rcsb pdb:3RPY|rcsb pdb:3RZB|rcsb pdb:3S00|rcsb pdb:3S0O|rcsb pdb:3S1H|rcsb pdb:3S2P|rcsb pdb:3SQQ|rcsb pdb:3SW4|rcsb pdb:3SW7|rcsb pdb:3TI1|rcsb pdb:3TIY|rcsb pdb:3TIZ|rcsb pdb:3TNW|rcsb pdb:3ULI|rcsb pdb:3UNJ|rcsb pdb:3UNK|rcsb pdb:3WBL|rcsb pdb:4ACM|rcsb pdb:4BCK|rcsb pdb:4BCM|rcsb pdb:4BCN|rcsb pdb:4BCO|rcsb pdb:4BCP|rcsb pdb:4BCQ|rcsb pdb:4BGH|rcsb pdb:4BZD|rcsb pdb:4CFM|rcsb pdb:4CFN|rcsb pdb:4CFU|rcsb pdb:4CFV|rcsb pdb:4CFW|rcsb pdb:4CFX|rcsb pdb:4D1X|rcsb pdb:4D1Z|rcsb pdb:4EK3|rcsb pdb:4EK4|rcsb pdb:4EK5|rcsb pdb:4EK6|rcsb pdb:4EK8|rcsb pdb:4EOI|rcsb pdb:4EOJ|rcsb pdb:4EOK|rcsb pdb:4EOL|rcsb pdb:4EOM|rcsb pdb:4EON|rcsb pdb:4EOO|rcsb pdb:4EOP|rcsb pdb:4EOQ|rcsb pdb:4EOR|rcsb pdb:4EOS|rcsb pdb:4ERW|rcsb pdb:4EZ3|rcsb pdb:4EZ7|rcsb pdb:4FKG|rcsb pdb:4FKI|rcsb pdb:4FKJ|rcsb pdb:4FKL|rcsb pdb:4FKO|rcsb pdb:4FKP|rcsb pdb:4FKQ|rcsb pdb:4FKR|rcsb pdb:4FKS|rcsb pdb:4FKT|rcsb pdb:4FKU|rcsb pdb:4FKV|rcsb pdb:4FKW|rcsb pdb:4FX3|rcsb pdb:4GCJ|rcsb pdb:4I3Z|rcsb pdb:4II5|rcsb pdb:4KD1|rcsb pdb:4LYN|rcsb pdb:5IEV|rcsb pdb:5IEX|rcsb pdb:5IEY|rcsb pdb:5IF1|rcsb pdb:5JQ5|rcsb pdb:5JQ8|rcsb pdb:5K4J|rcsb pdb:5L2W|rcsb pdb:5LMK|rcsb pdb:5MHQ|rcsb pdb:5NEV|rcsb pdb:5OO0|rcsb pdb:5OO1|rcsb pdb:5OO3|rcsb pdb:5OSJ|rcsb pdb:5OSM|rcsb pdb:5UQ1|rcsb pdb:5UQ2|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6GUB|rcsb pdb:6GUC|rcsb pdb:6GUE|rcsb pdb:6GUF|rcsb pdb:6GUH|rcsb pdb:6GUK|rcsb pdb:6GVA|rcsb pdb:6INL|rcsb pdb:6JGM|rcsb pdb:4NJ3|rcsb pdb:4RJ3|rcsb pdb:5A14|rcsb pdb:5AND|rcsb pdb:5ANE|rcsb pdb:5ANG|rcsb pdb:5ANI|rcsb pdb:5ANJ|rcsb pdb:5ANK|rcsb pdb:5ANO|rcsb pdb:5CYI|rcsb pdb:5D1J|rcsb pdb:5FP5|rcsb pdb:5FP6|rcsb pdb:6OQI|rcsb pdb:6P3W|rcsb pdb:6Q3B|rcsb pdb:6Q3C|rcsb pdb:6Q3F|rcsb pdb:6Q48|rcsb pdb:6Q49|rcsb pdb:6Q4A|rcsb pdb:6Q4B|rcsb pdb:6Q4C|rcsb pdb:6Q4D|rcsb pdb:6Q4E|rcsb pdb:6Q4F|rcsb pdb:6Q4G|rcsb pdb:6Q4H|rcsb pdb:6Q4I|rcsb pdb:6Q4J|rcsb pdb:6Q4K|rcsb pdb:6RIJ|rcsb pdb:6SG4|rcsb pdb:6YL1|rcsb pdb:6YL6|rcsb pdb:6YLK|rcsb pdb:7ACK|rcsb pdb:7B5L|rcsb pdb:7B5R|rcsb pdb:7E34|rcsb pdb:7KJS|rcsb pdb:7NVQ|reactome:R-HSA-1538133|reactome:R-HSA-171319|reactome:R-HSA-176187|reactome:R-HSA-176408|reactome:R-HSA-187577|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5693607|reactome:R-HSA-6804116|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-68911|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69017|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9661069|reactome:R-HSA-983231|dip:DIP-161N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:ysjMzOZyhhtpss+M7hJCqtLahFQ9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P24534	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P24385	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-375001|uniprotkb:Q6LEF0|ensembl:ENSP00000227507	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ccnd1_human(display_long)|uniprotkb:CCND1(gene name)|psi-mi:CCND1(display_short)|uniprotkb:BCL1(gene name synonym)|uniprotkb:PRAD1(gene name synonym)|uniprotkb:PRAD1 oncogene(gene name synonym)|uniprotkb:BCL-1 oncogene(gene name synonym)|uniprotkb:B-cell lymphoma 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_444284.1|ensembl:ENSG00000110092(gene)|ensembl:ENST00000227507(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010039"(response to iron ion)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070141"(response to UV-A)|go:"GO:0097421"(liver regeneration)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P24385|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:5VZU|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-1912408|reactome:R-HSA-3214858|reactome:R-HSA-6785807|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8853884|reactome:R-HSA-8878166|reactome:R-HSA-8934593|reactome:R-HSA-8951430|reactome:R-HSA-8951936|go:"GO:0044321"(response to leptin)|reactome:R-HSA-9018519|reactome:R-HSA-9634638|reactome:R-HSA-9661069|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-123N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:XIMa4dI7+QiodOusigAjalaEIJk9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P20248	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-457097|ensembl:ENSP00000274026|uniprotkb:Q2M3U6|uniprotkb:Q4W5P4|uniprotkb:Q6LER8|uniprotkb:A8K7B6	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ccna2_human(display_long)|uniprotkb:Cyclin A(gene name synonym)|uniprotkb:CCNA2(gene name)|psi-mi:CCNA2(display_short)|uniprotkb:CCN1(gene name synonym)|uniprotkb:CCNA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	ensembl:ENSG00000145386(gene)|ensembl:ENST00000274026(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033762"(response to glucagon)|refseq:NP_001228.1|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071373"(cellular response to luteinizing hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090102"(cochlea development)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR032447|interpro:IPR036915|interpro:IPR039361|mint:P20248|rcsb pdb:1E9H|rcsb pdb:1FIN|rcsb pdb:1H1P|rcsb pdb:1FVV|rcsb pdb:1GY3|rcsb pdb:1H1Q|rcsb pdb:1H1R|rcsb pdb:1H1S|rcsb pdb:1H24|rcsb pdb:1H25|rcsb pdb:1H26|rcsb pdb:1H27|rcsb pdb:1H28|rcsb pdb:1JST|rcsb pdb:1JSU|rcsb pdb:1OGU|rcsb pdb:1OI9|rcsb pdb:1OIU|rcsb pdb:1OIY|rcsb pdb:1OKV|rcsb pdb:1OKW|rcsb pdb:1OL1|rcsb pdb:1OL2|rcsb pdb:1P5E|rcsb pdb:1PKD|rcsb pdb:1QMZ|rcsb pdb:1URC|rcsb pdb:1VYW|rcsb pdb:2BKZ|rcsb pdb:2BPM|rcsb pdb:2C4G|rcsb pdb:6SG4|rcsb pdb:7ACK|rcsb pdb:7B5L|rcsb pdb:7B5R|rcsb pdb:7LUO|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-170145|reactome:R-HSA-171319|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-187577|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5689880|reactome:R-HSA-5693607|reactome:R-HSA-6804116|reactome:R-HSA-6804756|reactome:R-HSA-6804757|rcsb pdb:2C5N|rcsb pdb:2C5O|rcsb pdb:2C5V|rcsb pdb:2C5X|rcsb pdb:2C6T|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:2CJM|rcsb pdb:2WIH|rcsb pdb:2I40|rcsb pdb:2IW6|rcsb pdb:2IW8|rcsb pdb:2IW9|rcsb pdb:2UUE|rcsb pdb:2WIP|rcsb pdb:2WMA|rcsb pdb:2WMB|rcsb pdb:2WPA|rcsb pdb:2WXV|rcsb pdb:2X1N|rcsb pdb:3EID|rcsb pdb:3EJ1|rcsb pdb:3EOC|rcsb pdb:3F5X|rcsb pdb:4BCK|rcsb pdb:2UZB|rcsb pdb:2UZD|rcsb pdb:2UZE|rcsb pdb:2UZL|rcsb pdb:2V22|rcsb pdb:2WEV|rcsb pdb:2WFY|rcsb pdb:2WHB|rcsb pdb:4BCM|rcsb pdb:4BCN|rcsb pdb:4BCP|rcsb pdb:4CFM|rcsb pdb:4CFN|rcsb pdb:4CFU|rcsb pdb:4CFV|rcsb pdb:4CFW|rcsb pdb:4CFX|rcsb pdb:4EOI|rcsb pdb:4EOJ|rcsb pdb:4EOK|rcsb pdb:4EOL|rcsb pdb:4EOM|rcsb pdb:4EON|rcsb pdb:4EOO|rcsb pdb:4EOP|rcsb pdb:6Q6H|rcsb pdb:4EOQ|rcsb pdb:4EOR|rcsb pdb:4EOS|rcsb pdb:4FX3|rcsb pdb:5CYI|rcsb pdb:5IF1|rcsb pdb:5LMK|rcsb pdb:5NEV|rcsb pdb:6ATH|rcsb pdb:6RIJ|rcsb pdb:6GVA|rcsb pdb:6P3W|rcsb pdb:6Q6G|reactome:R-HSA-68911|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69273|reactome:R-HSA-69563|reactome:R-HSA-69656|dip:DIP-638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:eAkF93loT7w//7jrIC/Nlpy5iVc9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P12004	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P11802	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:P06493	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:O96020	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-375033|uniprotkb:O95439|ensembl:ENSP00000309181|ensembl:ENSP00000429089	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:ccne2_human(display_long)|uniprotkb:CCNE2(gene name)|psi-mi:CCNE2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	refseq:NP_477097.1|ensembl:ENST00000308108(transcript)|ensembl:ENST00000520509(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:0097135"(cyclin E2-CDK2 complex)|go:"GO:1903827"|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028858|interpro:IPR036915|interpro:IPR039361|reactome:R-HSA-1538133|reactome:R-HSA-187577|reactome:R-HSA-2559586|reactome:R-HSA-390471|reactome:R-HSA-6804116|reactome:R-HSA-69017|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-9661069|ensembl:ENSG00000175305(gene)|refseq:XP_016869446.1|refseq:XP_016869447.1|refseq:XP_016869448.1|dip:DIP-31733N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:urbnnQYqigb2gS6jMHWruQpct+s9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P38936	uniprotkb:C9J2U0	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	intact:EBI-21259318|ensembl:ENSP00000350625|uniprotkb:V5W643	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:c9j2u0_human(display_long)|uniprotkb:CCNE1(gene name)|psi-mi:CCNE1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259335|imex:IM-26691-103	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	interpro:IPR028858|ensembl:ENSG00000105173(gene)|ensembl:ENST00000357943(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	rogid:s17pjHZ0lN4UHaei5+jJoknwxsk9606	rigid:GzdjOAenPKaqmHYgWmiAUdWbNNI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q9NZM1	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-1994363|uniprotkb:Q5VWW2|uniprotkb:Q5VWW3|uniprotkb:Q5VWW4|uniprotkb:Q5VWW5|uniprotkb:Q7Z642|uniprotkb:Q8IWH0|uniprotkb:Q9HBU3|uniprotkb:Q9NZM0|uniprotkb:Q9ULL3|uniprotkb:Q9Y4U4|uniprotkb:B3KQN5|ensembl:ENSP00000352208	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:myof_human(display_long)|uniprotkb:MYOF(gene name)|psi-mi:MYOF(display_short)|uniprotkb:KIAA1207(gene name synonym)|uniprotkb:FER1L3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_038479.1|refseq:NP_579899.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029999|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q9NZM1|rcsb pdb:2DMH|rcsb pdb:2K2O|rcsb pdb:6EEL|ensembl:ENSG00000138119(gene)|ensembl:ENST00000359263(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006936"(muscle contraction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008015"(blood circulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061025"(membrane fusion)	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:YbWzqcootZO0/w6OLRqxZEEAu9U9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q9H932	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-21259418	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:q9h932_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	interpro:IPR031248|go:"GO:0004842"(ubiquitin-protein transferase activity)	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:0mNCLIEdl9i59B3dI4PljvgqNpA9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q6UB35	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-1046835|intact:EBI-28986171|ensembl:ENSP00000356290|uniprotkb:Q2TBF3|uniprotkb:Q8WVW0|uniprotkb:Q96HG8|uniprotkb:Q9H789|uniprotkb:Q9UFU8	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:c1tm_human(display_long)|uniprotkb:MTHFD1L(gene name)|psi-mi:MTHFD1L(display_short)|uniprotkb:FTHFSDC1(gene name synonym)|uniprotkb:Formyltetrahydrofolate synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	ensembl:ENSG00000120254(gene)|ensembl:ENST00000367321(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006760"(folic acid-containing compound metabolic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0015942"(formate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR027417|interpro:IPR036291|reactome:R-HSA-196757|refseq:NP_001229696.1|refseq:NP_001229697.1|refseq:NP_001229698.1|refseq:NP_056255.2|ensembl:ENST00000367307|ensembl:ENSP00000356276|ensembl:ENSP00000356290	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:lJRND1kcMEF99+fT1b+X8hfuLHM9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q16543	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q15834	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_006839.2|ensembl:ENSG00000175602(gene)|ensembl:ENST00000312579(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005912"(adherens junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR019359	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:Q14978	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:P80723	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:P48735	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:P24534	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:P08590	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-3909140|uniprotkb:Q9NRS8|uniprotkb:B2R534|ensembl:ENSP00000292327|ensembl:ENSP00000379210|ensembl:ENSP00000499406|ensembl:ENSP00000499577|ensembl:ENSP00000499624	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:myl3_human(display_long)|uniprotkb:MYL3(gene name)|psi-mi:MYL3(display_short)|uniprotkb:Cardiac myosin light chain 1(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Ventricular/slow twitch myosin alkali light chain(gene name synonym)|uniprotkb:Ventricular myosin alkali light chain(gene name synonym)|uniprotkb:Ventricular myosin light chain 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_000249.1|ensembl:ENSG00000160808(gene)|ensembl:ENST00000292327(transcript)|ensembl:ENST00000395869(transcript)|ensembl:ENST00000653454(transcript)|ensembl:ENST00000654597(transcript)|ensembl:ENST00000662933(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030017"(sarcomere)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P08590|rcsb pdb:5TBY|reactome:R-HSA-390522	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:c6a6WDyl6ICfx4FvSdh2sh8zAaU9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:O00161	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49716	uniprotkb:E9PQ49	intact:EBI-7962058|intact:MINT-6609320|uniprotkb:Q2M2X9|uniprotkb:Q14937|ensembl:ENSP00000386165	intact:EBI-21259404|ensembl:ENSP00000434448|ensembl:ENSP00000487710	psi-mi:cebpd_human(display_long)|uniprotkb:CEBPD(gene name)|psi-mi:CEBPD(display_short)|uniprotkb:Nuclear factor NF-IL6-beta(gene name synonym)	psi-mi:e9pq49_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259421|imex:IM-26691-65	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005186.2|dip:DIP-146N|ensembl:ENSG00000221869(gene)|ensembl:ENST00000408965(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|reactome:R-HSA-381340|reactome:R-HSA-6785807|reactome:R-HSA-9610379	ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000632115(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR018940	-	function:"C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages"|comment:mint	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:YFcSMGzxG3TgSYEpseQbB6vG/CE9606	rogid:vUGfRutmqRytvkHqhugRcy4jl9U9606	rigid:cOb9ds3bm2IhoZ4NEC8JsvPmm+Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q9Y6G5	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550310|uniprotkb:Q9P077|uniprotkb:D3DT07|ensembl:ENSP00000274458	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comda_human(display_long)|uniprotkb:COMMD10(gene name)|psi-mi:COMMD10(display_short)|uniprotkb:HSPC305(orf name)|uniprotkb:PTD002(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_057228.1|refseq:NP_001295009.1|ensembl:ENSG00000145781(gene)|ensembl:ENST00000274458(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037361|mint:Q9Y6G5|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:yRozKabxLJMAEbM9QfLGOQCzRxE9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q9Y281	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q9P000	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550510|uniprotkb:Q9H0R0|uniprotkb:Q96FI2|uniprotkb:E9PAN2|ensembl:ENSP00000263401	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd9_human(display_long)|uniprotkb:COMMD9(gene name)|psi-mi:COMMD9(display_short)|uniprotkb:HSPC166(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_054905.2|refseq:NP_001294866.1|ensembl:ENSG00000110442(gene)|ensembl:ENST00000263401(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006814"(sodium ion transport)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR017920|interpro:IPR037360|rcsb pdb:4NKN|rcsb pdb:4OE9|rcsb pdb:6BP6|reactome:R-HSA-6798695|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:2MhNQZU+OGXGZ2nuSi1AS8+bpz09606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q9NX08	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_060315.1|ensembl:ENSG00000169019(gene)|ensembl:ENST00000381571(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9NX08|reactome:R-HSA-8951664|refseq:NP_001316597.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q9H0A8	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550064|uniprotkb:Q7L637|uniprotkb:Q9NX43|uniprotkb:B2RBN4|uniprotkb:H3BUL2|ensembl:ENSP00000267935|ensembl:ENSP00000433662	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd4_human(display_long)|uniprotkb:COMMD4(gene name)|psi-mi:COMMD4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001271306.1|refseq:NP_060298.2|refseq:NP_001271307.1|ensembl:ENSG00000140365(gene)|ensembl:ENST00000267935(transcript)|ensembl:ENST00000480484(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR017920|interpro:IPR037356|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:v1pkDNc18f7sZM/89Gv0bho9GN89606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q96D71	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q92598	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q92499	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q8TCE6	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-725416|uniprotkb:Q9NXW4|uniprotkb:B1AMV6|uniprotkb:B4DDC3|uniprotkb:D3DRC8|ensembl:ENSP00000354688	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:den10_human(display_long)|uniprotkb:DENND10(gene name)|psi-mi:DENND10(display_short)|uniprotkb:FAM45A(gene name synonym)|uniprotkb:Protein FAM45A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_996892.1|refseq:NP_001290040.1|refseq:NP_001290041.1|refseq:NP_001290042.1|ensembl:ENSG00000119979(gene)|ensembl:ENST00000361432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR037516|interpro:IPR042431|mint:Q8TCE6|refseq:XP_016871750.1|refseq:XP_016871751.1|refseq:XP_016871752.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:y2TwrFW/ss6WtsUMVIVRCG8lEKk9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q8NDX6	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-2602428|uniprotkb:A8K9M9|ensembl:ENSP00000409463	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:zn740_human(display_long)|uniprotkb:ZNF740(gene name)|psi-mi:ZNF740(display_short)|uniprotkb:TB7(gene name synonym)|uniprotkb:OriLyt TD-element-binding protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001004304.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000139651(gene)|ensembl:ENST00000416904(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:2i7f+rUftAUiFntFARDjwFBLfrs9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q8N668	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q86X83	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550220|uniprotkb:Q9H3L5|uniprotkb:Q9Y5V1|uniprotkb:Q561V4|ensembl:ENSP00000419475	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd2_human(display_long)|uniprotkb:COMMD2(gene name)|psi-mi:COMMD2(display_short)|uniprotkb:HSPC042(orf name)|uniprotkb:My004(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_057178.2|ensembl:ENSG00000114744(gene)|ensembl:ENST00000473414(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037354|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:407iXgoqRlBDNBmFvM9pGqZ4esI9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q86VX2	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1550280|uniprotkb:A2BHJ2|uniprotkb:Q5JYB0|uniprotkb:Q96SI7|uniprotkb:Q9BW53|uniprotkb:B3KTZ2|ensembl:ENSP00000278980	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:comd7_human(display_long)|uniprotkb:COMMD7(gene name)|psi-mi:COMMD7(display_short)|uniprotkb:C20orf92(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001092809.1|refseq:NP_444269.2|ensembl:ENSG00000149600(gene)|ensembl:ENST00000278980(transcript)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|interpro:IPR037358|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:9mVwUwXsqGS+xFwRa4KbMylvaps9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q7Z3J2	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q567U6	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q13283	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:Q09666	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:u1oecAyIihgxzfTz0jholE8wksA9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:P62841	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:O75531	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:O60826	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:B1AKQ8	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-6190833|ensembl:ENSP00000416651	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:b1akq8_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	ensembl:ENSG00000078369(gene)|ensembl:ENST00000437146(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR036322	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:BUB/7mf+WlDyk4rDXHXUrW9rKWE9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBI1	uniprotkb:A8MTY9	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	intact:EBI-11080083|ensembl:ENSP00000381964	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:a8mty9_human(display_long)|uniprotkb:VPS26C(gene name)|psi-mi:VPS26C(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259462|imex:IM-26691-105	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	ensembl:ENSG00000157538(gene)|ensembl:ENST00000398998(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006886"(intracellular protein transport)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|refseq:NP_001317950.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rogid:8FKLoHbp4OgzajKvzIYK///ccPQ9606	rigid:rNhXXR9Ld08Olw6o6l/FIK5iPGQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00264	uniprotkb:Q16678	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	intact:EBI-1055133|uniprotkb:Q93089|uniprotkb:Q9H316|uniprotkb:Q5TZW8|ensembl:ENSP00000478561|ensembl:ENSP00000483678	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:cp1b1_human(display_long)|uniprotkb:CYPIB1(gene name synonym)|uniprotkb:CYP1B1(gene name)|psi-mi:CYP1B1(display_short)|uniprotkb:Hydroperoxy icosatetraenoate dehydratase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259534|imex:IM-26691-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	refseq:NP_000095.2|ensembl:ENSG00000138061(gene)|ensembl:ENST00000610745(transcript)|ensembl:ENST00000614273(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0020037"(heme binding)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046466"(membrane lipid catabolic process)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0061304"(retinal blood vessel morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070330"(aromatase activity)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0097267"(omega-hydroxylase P450 pathway)|go:"GO:0101020"(estrogen 16-alpha-hydroxylase activity)|go:"GO:0106256"(hydroperoxy icosatetraenoate dehydratase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR032971|interpro:IPR036396|rcsb pdb:3PM0|rcsb pdb:6IQ5|reactome:R-HSA-211976|reactome:R-HSA-2142670|reactome:R-HSA-2142816|reactome:R-HSA-5579000|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rogid:2VJK4lLtHFWOsLQPBDXweKplk+09606	rigid:y83dOr1nD0GBnEjfPZc3ljuS6bE	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9UQ80	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9Y5V3	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9Y520	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055987.2|refseq:XP_006711301.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|ensembl:ENST00000338920|ensembl:ENSP00000343629|ensembl:ENSG00000117523|ensembl:ENST00000426496|ensembl:ENSP00000410219|ensembl:ENST00000647382|ensembl:ENSP00000495867|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9Y2Z0	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9Y262	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9UNX4	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-727436|ensembl:ENSP00000308179	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_006775.1|ensembl:ENSG00000065183(gene)|ensembl:ENST00000349139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q9UNX4|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9ULX6	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9UL15	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9UBQ5	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9H307	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9H1I8	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9H0S4	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-2515241|ensembl:ENSP00000350698|uniprotkb:Q96NV8|uniprotkb:B3KXP4|uniprotkb:Q96GM0|uniprotkb:G5E955|uniprotkb:Q9UI98	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ddx47_human(display_long)|uniprotkb:DDX47(gene name)|psi-mi:DDX47(display_short)|uniprotkb:DEAD box protein 47(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000213782(gene)|ensembl:ENST00000358007(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044765|mint:Q9H0S4|rcsb pdb:3BER|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_057439.2|refseq:NP_957518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:AhH5kg/8cw6L5385wUw4PR243rY9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9BV38	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q9BPX3	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:G45XQBcnTeSunRz57s6lJErxvjo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q99613	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q969Q0	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:+jT5oFy79StEavkvHz6j/36g/qg9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q93008	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q92769	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q8WVZ9	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-473695|uniprotkb:Q5T6Y7|uniprotkb:Q8NB99|uniprotkb:B5TZ86|uniprotkb:Q9H0I6|ensembl:ENSP00000368797	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:kbtb7_human(display_long)|uniprotkb:KBTBD7(gene name)|psi-mi:KBTBD7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000120696(gene)|ensembl:ENST00000379483(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q8WVZ9|reactome:R-HSA-5658442|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_115514.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:HgDy3oyjsoNXtT6vFydN4KZGsfw9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q8NFH3	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q8N3C0	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q5JSZ5	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q5H9R7	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q53EL6	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-935824|uniprotkb:O15501|uniprotkb:Q5VZS6|uniprotkb:Q6PJI5|uniprotkb:Q8TAR5|uniprotkb:Q99834|intact:EBI-2514227|uniprotkb:B2RCV4|uniprotkb:B5ME91|ensembl:ENSP00000280154	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:pdcd4_human(display_long)|uniprotkb:PDCD4(gene name)|psi-mi:PDCD4(display_short)|uniprotkb:H731(gene name synonym)|uniprotkb:Nuclear antigen H731-like(gene name synonym)|uniprotkb:Neoplastic transformation inhibitor protein(gene name synonym)|uniprotkb:Protein 197/15a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055271.2|refseq:NP_663314.1|dip:DIP-29756N|ensembl:ENSG00000150593(gene)|ensembl:ENST00000280154(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|rcsb pdb:2GGF|rcsb pdb:2KZT|rcsb pdb:2RG8|rcsb pdb:2ZU6|rcsb pdb:3EIJ|reactome:R-HSA-8950505	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:kkqDk2CCFvHpSCKNDzV4wqSm1HE9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q15386	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q15021	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q14978	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q14257	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q14152	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q13442	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q13347	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:fogC6nSNmIynV2ziHZboT9laA3M9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:Q04637	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P84090	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P78344	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P60228	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P55884	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P55084	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P48634	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSP00000372956|ensembl:ENSP00000387477|ensembl:ENSP00000387910|ensembl:ENSP00000396812|ensembl:ENSP00000400540|ensembl:ENSP00000404619|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000413977|ensembl:ENSP00000415182|ensembl:ENSP00000415363	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSP00000372956|ensembl:ENSP00000404619|ensembl:ENSP00000415182|ensembl:ENSP00000415363|ensembl:ENSP00000387910|ensembl:ENSP00000413977|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000400540|ensembl:ENSP00000387477|ensembl:ENSP00000396812|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSG00000204469(gene)|ensembl:ENSG00000206427(gene)|ensembl:ENSG00000225164(gene)|ensembl:ENSG00000225748(gene)|ensembl:ENSG00000226618(gene)|ensembl:ENSG00000231370(gene)|ensembl:ENSG00000231825(gene)|ensembl:ENST00000376007(transcript)|ensembl:ENST00000376033(transcript)|ensembl:ENST00000383455(transcript)|ensembl:ENST00000383464(transcript)|ensembl:ENST00000414956(transcript)|ensembl:ENST00000416335(transcript)|ensembl:ENST00000422962(transcript)|ensembl:ENST00000428775(transcript)|ensembl:ENST00000430737(transcript)|ensembl:ENST00000432252(transcript)|ensembl:ENST00000435971(transcript)|ensembl:ENST00000439762(transcript)|ensembl:ENST00000454306(transcript)|ensembl:ENST00000458561(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P41091	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001406.1|ensembl:ENSG00000130741(gene)|ensembl:ENST00000253039(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR044127|interpro:IPR044128|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P31948	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P28370	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P25685	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P20042	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-711977|ensembl:ENSP00000364119|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000125977(gene)|ensembl:ENST00000374980(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_003899.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P17858	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P07900	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P07305	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:P05198	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O95831	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O95816	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O95071	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O75822	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O75694	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O60841	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-928530|uniprotkb:O95805|uniprotkb:Q9UF81|uniprotkb:Q9UMN7|uniprotkb:Q53RV7|uniprotkb:Q53SI8|ensembl:ENSP00000289371	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if2p_human(display_long)|uniprotkb:EIF5B(gene name)|psi-mi:EIF5B(display_short)|uniprotkb:IF2(gene name synonym)|uniprotkb:KIAA0741(gene name synonym)|uniprotkb:Translation initiation factor IF-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_056988.3|ensembl:ENSG00000158417(gene)|ensembl:ENST00000289371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|mint:O60841|reactome:R-HSA-72706	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:5rLXO0ZcDcwLGOM4ZGA4fvQJ33U9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O60739	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000114784(gene)|ensembl:ENST00000232905(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|refseq:NP_005866.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O60287	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-1762349|uniprotkb:D3DSE5|uniprotkb:Q96NX1|uniprotkb:Q9NYQ1|ensembl:ENSP00000372199	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:npa1p_human(display_long)|uniprotkb:URB1(gene name)|psi-mi:URB1(display_short)|uniprotkb:C21orf108(gene name synonym)|uniprotkb:KIAA0539(gene name synonym)|uniprotkb:NPA1(gene name synonym)|uniprotkb:URB1 ribosome biogenesis 1 homolog(gene name synonym)|uniprotkb:NOP254(gene name synonym)|uniprotkb:Nucleolar protein 254 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_055640.2|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844|ensembl:ENSG00000142207(gene)|ensembl:ENST00000382751(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:tolq2rVG0N5qy3qGiIkPj8xtVis9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O43776	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-373505|uniprotkb:Q53GU6|uniprotkb:B4DG16|ensembl:ENSP00000256854	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:sync_human(display_long)|uniprotkb:NARS1(gene name)|psi-mi:NARS1(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:Asparaginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:NARS(gene name synonym)|uniprotkb:NRS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004530.1|ensembl:ENSG00000134440(gene)|ensembl:ENST00000256854(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|go:"GO:0016477"(cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031728"(CCR3 chemokine receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:4ZYA|rcsb pdb:5XIX|reactome:R-HSA-379716	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:yCKLNQEoXyLaJC0PpYOoefQawss9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O15372	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-709735|ensembl:ENSP00000429931	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O15371	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O14602	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-286439|uniprotkb:Q9BS77|ensembl:ENSP00000354722	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:if1ay_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:EIF1AY(gene name)|psi-mi:EIF1AY(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_004672.2|refseq:NP_001265541.1|ensembl:ENSG00000198692(gene)|ensembl:ENST00000361365(transcript)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:8nbys9cgdyGlFgYev/Ws9Q0cu6s9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O00743	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:O00303	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:K7EL20	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21258967|ensembl:ENSP00000465882	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:k7el20_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000130811(gene)|ensembl:ENST00000588709(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:uZXb01pYRdoP+H8dfr/QBc2/Txo9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:K7EIH8	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21259594|ensembl:ENSP00000464756	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:k7eih8_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000168259(gene)|ensembl:ENST00000590348(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:/fSmMnrnj/XjslVdpKlrM2w3nqA9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:H3BS86	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21259582|ensembl:ENSP00000456591	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:h3bs86_human(display_long)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000103266(gene)|ensembl:ENST00000567173(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041312	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:kIb5YkvjJXhsREYdDvtNbuGPOdE9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:H0YIB4	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21259571|ensembl:ENSP00000449030	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:h0yib4_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000111786(gene)|ensembl:ENST00000550458(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:9BMC6MJa/41h6TqzB+1Bcm/MLvI9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:H0YCQ8	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21258927|ensembl:ENSP00000432139	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:h0ycq8_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000149100(gene)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040750|ensembl:ENST00000526267(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:YKZM4oKZZ19CTTf2uGNjPgZ3eUQ9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:F5H1C8	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21259559|ensembl:ENSP00000445773	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IY21	uniprotkb:E7EUI8	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-21259543|ensembl:ENSP00000395599	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:e7eui8_human(display_long)|uniprotkb:G6PD(gene name)|psi-mi:G6PD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259607|imex:IM-26691-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000160211(gene)|ensembl:ENST00000439227(transcript)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0034451"(centriolar satellite)|go:"GO:0050661"(NADP binding)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:wt5X5nACy6+bKSp2CgfaLoWwu+U9606	rigid:jpHnEYK3pa//aCGxQ6Ip4ejnqbA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:Q9NZN4	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-3910174|uniprotkb:B4DNU6|uniprotkb:Q96CB6|uniprotkb:B2RDH9|ensembl:ENSP00000263277	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:ehd2_human(display_long)|uniprotkb:EHD2(gene name)|psi-mi:EHD2(display_short)|uniprotkb:PAST2(gene name synonym)|uniprotkb:PAST homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	refseq:NP_055416.2|ensembl:ENSG00000024422(gene)|ensembl:ENST00000263277(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9NZN4|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:cbY+YP5JhaapDbuPjW06Ji3VvzU9606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:Q9NRW7	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-1782543|uniprotkb:Q15715|uniprotkb:Q9Y4Z6|uniprotkb:Q5T4P6|uniprotkb:F5H8K1|uniprotkb:Q53FR8|uniprotkb:D3DUZ9|ensembl:ENSP00000495563	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:vps45_human(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:VPS45A(gene name synonym)|uniprotkb:VPS45B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	dip:DIP-46823N|refseq:NP_009190.2|refseq:NP_001266282.1|refseq:NP_001266283.1|ensembl:ENSG00000136631(gene)|ensembl:ENST00000644510(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-HSA-6811438|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:EO8eXkh8EW/0AN2p5OqHL4yvXV09606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:Q9H4M9	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-490691|uniprotkb:O14611|uniprotkb:Q2M3Q4|uniprotkb:Q9UNR3|ensembl:ENSP00000320516|ensembl:ENSP00000352354	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:ehd1_human(display_long)|uniprotkb:Testilin(gene name synonym)|uniprotkb:CDABP0131(orf name)|uniprotkb:EHD1(gene name)|psi-mi:EHD1(display_short)|uniprotkb:PAST(gene name synonym)|uniprotkb:PAST1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_006786.2|refseq:XP_011543041.1|refseq:NP_001269373.1|refseq:NP_001269374.1|ensembl:ENSG00000110047(gene)|ensembl:ENST00000320631(transcript)|ensembl:ENST00000359393(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H4M9|rcsb pdb:2JQ6|rcsb pdb:2KFF|rcsb pdb:2KFG|rcsb pdb:2KFH|rcsb pdb:2KSP|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:txUfRMtv6SbBqKKJ1DVM6K/pj2Y9606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:Q96JJ7	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:O95816	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:O76031	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:O60884	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H223	uniprotkb:H0YL12	intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325	intact:EBI-21259817|ensembl:ENSP00000453017	psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym)	psi-mi:h0yl12_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259829|imex:IM-26691-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223	go:"GO:0005759"(mitochondrial matrix)|ensembl:ENSG00000140374(gene)|ensembl:ENST00000560345(transcript)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR029035|interpro:IPR033947	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606	rogid:Cw4dRHI2p2B3Ge4EJBFj2UT9b2Q9606	rigid:uLNRnP91sOfcMhGAGulu2U4l96A	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q9Y4L1	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q9UNS2	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q96HE7	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-2564539|uniprotkb:A8K9X4|uniprotkb:A8MYW1|uniprotkb:Q7LD45|uniprotkb:Q9P1Q9|uniprotkb:Q9UKV6|ensembl:ENSP00000379042	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:ero1a_human(display_long)|uniprotkb:ERO1A(gene name)|psi-mi:ERO1A(display_short)|uniprotkb:ERO1L(gene name synonym)|uniprotkb:Endoplasmic oxidoreductin-1-like protein(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase alpha(gene name synonym)|uniprotkb:Oxidoreductin-1-L-alpha(gene name synonym)|uniprotkb:UNQ434/PRO865(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_055399.1|ensembl:ENSG00000197930(gene)|ensembl:ENST00000395686(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0010260"(animal organ senescence)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030425"(dendrite)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071949"(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q96HE7|rcsb pdb:3AHQ|rcsb pdb:3AHR|reactome:R-HSA-264876|reactome:R-HSA-3299685	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:7IOP99IQt+7MBAQ0LKqPo5mFylo9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q969V3	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1056979|uniprotkb:O75252|uniprotkb:Q6FI60|uniprotkb:Q6ZMB7|uniprotkb:Q8TAT7|uniprotkb:Q96H48|uniprotkb:Q96IS7|uniprotkb:Q9BQH9|uniprotkb:Q9BTX4|uniprotkb:Q9NPP2|uniprotkb:D6W613|ensembl:ENSP00000246117	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:ncln_human(display_long)|uniprotkb:NCLN(gene name)|psi-mi:NCLN(display_short)|uniprotkb:Nicastrin-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_064555.2|refseq:NP_001308392.1|ensembl:ENSG00000125912(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR007484(Peptidase M28)|interpro:IPR016574(Nicalin)|mint:Q969V3|rcsb pdb:6W6L|ensembl:ENST00000246117(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:h2Md0pyypG6ZFLWOxHxQvJKFg/k9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q92626	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-3942679|uniprotkb:Q4KMG2|uniprotkb:A8QM65|uniprotkb:D6W4Y0|ensembl:ENSP00000252804	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:pxdn_human(display_long)|uniprotkb:PXDN(gene name)|psi-mi:PXDN(display_short)|uniprotkb:KIAA0230(gene name synonym)|uniprotkb:MG50(gene name synonym)|uniprotkb:PRG2(gene name synonym)|uniprotkb:VPO(gene name synonym)|uniprotkb:VPO1(gene name synonym)|uniprotkb:Melanoma-associated antigen MG50(gene name synonym)|uniprotkb:Vascular peroxidase 1(gene name synonym)|uniprotkb:p53-responsive gene 2 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_036425.1|ensembl:ENSG00000130508(gene)|ensembl:ENST00000252804(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005152"(interleukin-1 receptor antagonist activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0019806"(bromide peroxidase activity)|go:"GO:0020037"(heme binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010255(Haem peroxidase)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR019791|interpro:IPR032675|interpro:IPR034824|interpro:IPR034828|interpro:IPR036179|interpro:IPR037120|reactome:R-HSA-2243919	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:/rKYEUb2yy8NEm9zbIrXyhQ94o09606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q8TEM1	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q8NBJ5	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1057068|uniprotkb:Q8NC64|ensembl:ENSP00000252599	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:gt251_human(display_long)|uniprotkb:COLGALT1(gene name)|psi-mi:COLGALT1(display_short)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 1"(gene name synonym)|uniprotkb:GLT25D1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym)|uniprotkb:PSEC0241(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_078932.2|ensembl:ENSG00000130309(gene)|ensembl:ENST00000252599(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:1904028"(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|mint:Q8NBJ5|reactome:R-HSA-1650814	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:nB7wFmsUKfA2+PrPaqw08fQpJRs9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q15155	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q13616	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q08380	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:Q02809	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-357174|ensembl:ENSP00000196061|uniprotkb:Q96AV9|uniprotkb:Q9H132|uniprotkb:B4DR87|intact:EBI-21357524	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:plod1_human(display_long)|uniprotkb:PLOD(gene name synonym)|uniprotkb:PLOD1(gene name)|psi-mi:PLOD1(display_short)|uniprotkb:LLH(gene name synonym)|uniprotkb:Lysyl hydroxylase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000083444(gene)|ensembl:ENST00000196061(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:Q02809|reactome:R-HSA-1650814|refseq:NP_000293.2|refseq:NP_001303249.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:q0eJHb8L3qTbN1PnjQ8L0PcpOLw9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P63208	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P61201	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1050386|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q6FGP4|uniprotkb:Q9BY54|uniprotkb:Q9R249|uniprotkb:Q9UNI2|uniprotkb:Q9UNQ5|ensembl:ENSP00000373553	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:csn2_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:COPS2(gene name)|psi-mi:COPS2(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:TRIP15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_001137359.1|refseq:NP_004227.1|ensembl:ENSG00000166200(gene)|ensembl:ENST00000388901(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|mint:P61201|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6A73|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|dip:DIP-42076N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P50454	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P17931	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P11047	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P10909	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P10619	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-989654|uniprotkb:Q9BW68|uniprotkb:Q561W6|uniprotkb:Q5JZH1|uniprotkb:Q96KJ2|uniprotkb:Q9BR08|ensembl:ENSP00000361537|ensembl:ENSP00000475524|ensembl:ENSP00000493613|ensembl:ENSP00000191018|uniprotkb:B2R798	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:ppgb_human(display_long)|uniprotkb:Cathepsin A(gene name synonym)|uniprotkb:Carboxypeptidase C(gene name synonym)|uniprotkb:Protective protein for beta-galactosidase(gene name synonym)|uniprotkb:CTSA(gene name)|psi-mi:CTSA(display_short)|uniprotkb:PPGB(gene name synonym)|uniprotkb:Carboxypeptidase L(gene name synonym)|uniprotkb:Protective protein cathepsin A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000064601(gene)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|rcsb pdb:1IVY|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BXN|rcsb pdb:4AZ0|rcsb pdb:4AZ3|rcsb pdb:4CI9|rcsb pdb:4CIA|rcsb pdb:4CIB|rcsb pdb:4MWS|rcsb pdb:4MWT|rcsb pdb:6WIA|reactome:R-HSA-1660662|reactome:R-HSA-2132295|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695|ensembl:ENST00000191018(transcript)|ensembl:ENST00000372459(transcript)|ensembl:ENST00000607482(transcript)|ensembl:ENST00000646241(transcript)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|refseq:NP_000299.2|refseq:NP_001161066.1|refseq:NP_001121167.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:l/CZaKjZTuZu1ROoJJZVsxobYrQ9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P08236	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-2906879|uniprotkb:Q549U0|uniprotkb:Q96CL9|uniprotkb:B4E1F6|uniprotkb:E9PCV0|ensembl:ENSP00000302728	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:bglr_human(display_long)|uniprotkb:GUSB(gene name)|psi-mi:GUSB(display_short)|uniprotkb:Beta-G1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_000172.2|refseq:NP_001280033.1|refseq:NP_001280034.1|refseq:XP_005250354.1|refseq:NP_001271219.1|dip:DIP-29724N|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR023230|interpro:IPR023232|interpro:IPR036156|mint:P08236|rcsb pdb:1BHG|rcsb pdb:3HN3|reactome:R-HSA-2024096|reactome:R-HSA-2160916|reactome:R-HSA-2206292|reactome:R-HSA-6798695|ensembl:ENSG00000169919(gene)|ensembl:ENST00000304895(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019391"(glucuronoside catabolic process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030246"(carbohydrate binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:xF7O30YloSCIuXadCwiBoRBjSjA9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P07942	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P05556	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:P01137	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-779636|uniprotkb:Q9UCG4|uniprotkb:A8K792	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:tgfb1_human(display_long)|uniprotkb:TGFB1(gene name)|psi-mi:TGFB1(display_short)|uniprotkb:TGFB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_000651.3|mint:P01137|dip:DIP-5934N|go:"GO:0000165"(MAPK cascade)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003823"(antigen binding)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0014008"(positive regulation of microglia differentiation)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021915"(neural tube development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0034714"(type III transforming growth factor beta receptor binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043932"(ossification involved in bone remodeling)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045918"(negative regulation of cytolysis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048535"(lymph node development)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051098"(regulation of binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072562"(blood microparticle)|go:"GO:0085029"(extracellular matrix assembly)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|go:"GO:1905313"(transforming growth factor beta receptor signaling pathway involved in heart development)|go:"GO:1990402"(embryonic liver development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR003939(Transforming growth factor, beta 1)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR016319(Transforming growth factor-beta)|interpro:IPR017948|interpro:IPR029034|rcsb pdb:1KLA|rcsb pdb:1KLC|rcsb pdb:1KLD|rcsb pdb:3KFD|rcsb pdb:4KV5|rcsb pdb:5FFO|rcsb pdb:5VQP|rcsb pdb:6OM2|rcsb pdb:6P7J|reactome:R-HSA-114608|reactome:R-HSA-168277|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-3304356|reactome:R-HSA-3642279|reactome:R-HSA-3645790|reactome:R-HSA-3656532|reactome:R-HSA-3656535|reactome:R-HSA-381340|reactome:R-HSA-5689603|reactome:R-HSA-6785807|reactome:R-HSA-8941855|reactome:R-HSA-8941858|reactome:R-HSA-8951936	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:WjHm8ysG9Ab1pFfdtG9QbJeCdCw9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:O60568	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:O00469	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NRD1	uniprotkb:F5H4C6	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-21259859|ensembl:ENSP00000445055	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:f5h4c6_human(display_long)|uniprotkb:GNS(gene name)|psi-mi:GNS(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259874|imex:IM-26691-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000135677(gene)|ensembl:ENST00000545273(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0008449"(N-acetylglucosamine-6-sulfatase activity)|go:"GO:0030203"(glycosaminoglycan metabolic process)|interpro:IPR000917(Sulphatase)|interpro:IPR015981(N-acetylglucosamine-6-sulphatase, eukaryotic)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR024607	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:BmKvXev5KJ5RJ73F8tGleYDYlmk9606	rigid:cMHHcJcGmo8X7sOzJULtH/SXIwg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q9Y5X1	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q9NWU2	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q9NPA3	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-750096|uniprotkb:D3DWB2|ensembl:ENSP00000338706|ensembl:ENSP00000367735|ensembl:ENSP00000416670|ensembl:ENSP00000483547	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:m1ip1_human(display_long)|uniprotkb:Gastrulation-specific G12-like protein(gene name synonym)|uniprotkb:Mid1-interacting G12-like protein(gene name synonym)|uniprotkb:Protein STRAIT11499(gene name synonym)|uniprotkb:MID1IP1(gene name)|psi-mi:MID1IP1(display_short)|uniprotkb:MIG12(gene name synonym)|uniprotkb:Spot 14-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_001092260.1|refseq:NP_001092261.1|refseq:NP_067065.1|ensembl:ENSG00000165175(gene)|ensembl:ENST00000336949(transcript)|ensembl:ENST00000378474(transcript)|ensembl:ENST00000457894(transcript)|ensembl:ENST00000614558(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0051258"(protein polymerization)|go:"GO:0051351"(positive regulation of ligase activity)|interpro:IPR009786(Thyroid hormone-inducible hepatic Spot 14)|mint:Q9NPA3|reactome:R-HSA-200425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:kB3vPijNxsKIH/K5NXkj4BIzneA9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q9H871	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-2797992|uniprotkb:Q6NTF0|uniprotkb:Q9H9H2|uniprotkb:Q9H6W5|uniprotkb:D6W5M6|ensembl:ENSP00000283632	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:rmd5a_human(display_long)|uniprotkb:RMND5A(gene name)|psi-mi:RMND5A(display_short)|uniprotkb:P44CTLH(gene name synonym)|uniprotkb:Protein RMD5 homolog A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_073617.1|ensembl:ENSG00000153561(gene)|ensembl:ENST00000283632(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR037680|interpro:IPR044063|mint:Q9H871	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:+wLGFpC1YJ1y6PVi15799YxByKI9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q9H7D7	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-1046864|uniprotkb:A0MNN3|uniprotkb:Q4G100|uniprotkb:Q59EC4|uniprotkb:Q5GLZ9|uniprotkb:Q86UY4|uniprotkb:Q9H3C2|ensembl:ENSP00000504428|intact:EBI-1642504	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:wdr26_human(display_long)|uniprotkb:CUL4- and DDB1-associated WDR protein 2(gene name synonym)|uniprotkb:Myocardial ischemic preconditioning up-regulated protein 2(gene name synonym)|uniprotkb:WDR26(gene name)|psi-mi:WDR26(display_short)|uniprotkb:CDW2(gene name synonym)|uniprotkb:MIP2(gene name synonym)|uniprotkb:PRO0852(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9H7D7|ensembl:ENSG00000162923(gene)|ensembl:ENST00000678917(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|refseq:NP_001108585.2|refseq:NP_079436.4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:HRA6f68aldUqB1rVa7uM9srSyR49606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q96S59	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q93009	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q93008	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q8IUR7	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-1049469|uniprotkb:Q6PIL2|uniprotkb:Q96D19|uniprotkb:Q96HZ5|uniprotkb:Q9NV02|uniprotkb:Q9NV94|uniprotkb:Q9Y4R9|uniprotkb:A8K0L2|uniprotkb:D3DNE6|uniprotkb:B7Z441|uniprotkb:B7Z453|uniprotkb:F5GWK4|ensembl:ENSP00000419413	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:armc8_human(display_long)|uniprotkb:ARMC8(gene name)|psi-mi:ARMC8(display_short)|uniprotkb:S863-2(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_054873.2|refseq:NP_056211.2|refseq:NP_998819.1|refseq:XP_011510934.1|refseq:XP_011510935.1|refseq:NP_001253970.1|refseq:NP_001253971.1|refseq:NP_001269271.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034657"(GID complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038739|mint:Q8IUR7|rcsb pdb:7NSC|reactome:R-HSA-6798695|ensembl:ENSG00000114098(gene)|ensembl:ENST00000469044(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|refseq:XP_006713627.1|refseq:XP_006713628.1|refseq:XP_006713629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:9QXdCIwU8zeZ94oQ7JJNDVD2NDk9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q7L5Y9	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-10984762|ensembl:ENSP00000302830|uniprotkb:O95285|uniprotkb:Q5JB54|uniprotkb:Q6ZRD6|uniprotkb:Q9NW84|uniprotkb:Q9H9Z4|uniprotkb:Q9BQ11|uniprotkb:Q9H9V6	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:maea_human(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:Cell proliferation-inducing gene 5 protein(gene name synonym)|uniprotkb:EMP(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 10 protein(gene name synonym)|uniprotkb:Macrophage erythroblast attacher(gene name synonym)|uniprotkb:P44EMLP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_001017405.1|refseq:NP_001284360.1|refseq:NP_005873.2|ensembl:ENSG00000090316(gene)|ensembl:ENST00000303400(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063|mint:Q7L5Y9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q6VN20	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-310569|intact:EBI-1056526|uniprotkb:A4FTY2|uniprotkb:Q9P264|intact:EBI-10984753|ensembl:ENSP00000316589|uniprotkb:B4DID0|uniprotkb:B4DQH9|uniprotkb:E7EW27	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:rbp10_human(display_long)|uniprotkb:RANBP10(gene name)|psi-mi:RANBP10(display_short)|uniprotkb:KIAA1464(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_065901.1|refseq:NP_001307167.1|refseq:NP_001307168.1|refseq:NP_001307169.1|ensembl:ENSG00000141084(gene)|ensembl:ENST00000317506(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q6VN20|reactome:R-HSA-8851805	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:DaNPLQf0T/+lsKrL+uhGtWXG0pI9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q15370	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q13501	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:Q04637	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:P23921	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:O00469	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:K7ENE2	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-21259967|ensembl:ENSP00000466908	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:k7ene2_human(display_long)|uniprotkb:GID4(gene name)|psi-mi:GID4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENSG00000141034(gene)|ensembl:ENST00000481836(transcript)|interpro:IPR018618	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:PObPghdJRRvU+eV0m69Sar6uFP09606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P30793	uniprotkb:J3KSN0	intact:EBI-958183|uniprotkb:Q9Y4I8|ensembl:ENSP00000378890|ensembl:ENSP00000419045|uniprotkb:Q6FHY7	intact:EBI-21259955|ensembl:ENSP00000462563	psi-mi:gch1_human(display_long)|uniprotkb:GCH1(gene name)|psi-mi:GCH1(display_short)|uniprotkb:DYT5(gene name synonym)|uniprotkb:GCH(gene name synonym)|uniprotkb:GTP cyclohydrolase I(gene name synonym)	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21259975|imex:IM-26691-181	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131979(gene)|ensembl:ENST00000395514(transcript)|ensembl:ENST00000491895(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042559"(pteridine-containing compound biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048265"(response to pain)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|rcsb pdb:1FB1|rcsb pdb:6Z80|rcsb pdb:6Z85|rcsb pdb:6Z86|rcsb pdb:6Z87|rcsb pdb:6Z88|rcsb pdb:6Z89|reactome:R-HSA-1474151|refseq:NP_000152.1|refseq:NP_001019195.1|refseq:NP_001019241.1|refseq:NP_001019242.1	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/21	rogid:9z/ipW7g2/eM/he2GvH8TndDK9I9606	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rigid:M0GYuj0MvEPjgulgazU8WkH8uSA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:Q9H444	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:Q5TCU3	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-21260047|ensembl:ENSP00000367541	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:q5tcu3_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|ensembl:ENSG00000198467(gene)|ensembl:ENST00000329305(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|refseq:NP_001288155.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:kX9YiC30bV5utZmy/Goq1V6H6SU9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P63104	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P63000	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P62258	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P62195	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P61981	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P53814	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-1199956|intact:EBI-1199983|uniprotkb:Q8N4H8|uniprotkb:Q8WWW1|uniprotkb:Q8WWW2|uniprotkb:O00569|uniprotkb:O95769|uniprotkb:O95937|uniprotkb:Q9P1S8|uniprotkb:Q9UIT1|uniprotkb:Q9UIT2|ensembl:ENSP00000328635	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:smtn_human(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	ensembl:ENSG00000183963(gene)|ensembl:ENST00000347557(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:P53814|rcsb pdb:2D87|refseq:NP_001193946.1|refseq:NP_001193947.1|refseq:NP_008863.3|refseq:NP_599031.1|refseq:NP_599032.2|ensembl:ENST00000333137|ensembl:ENSP00000329532|ensembl:ENSP00000328635|ensembl:ENST00000358743|ensembl:ENSP00000351593	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:na+f9ZixP42TZZ0uD5P5tzaroFA9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P51570	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P31946	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P27348	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P25205	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P15170	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:P09493	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P55040	uniprotkb:H3BQF1	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	intact:EBI-21260035|ensembl:ENSP00000455749	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:h3bqf1_human(display_long)|uniprotkb:APRT(gene name)|psi-mi:APRT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260056|imex:IM-26691-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	ensembl:ENSG00000198931(gene)|ensembl:ENST00000567713(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009116"(nucleoside metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	rogid:tXqCpp0mjPAZWDXjjhGcUE8Qns89606	rigid:sy+S+w3C8OIxErwSjoSUHhSwl5o	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:Q9UL15	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:Q9UH99	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:Q92598	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:Q58FF8	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-2961708	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P54652	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P49720	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P34932	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P31948	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P31689	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:P25685	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:O95816	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:O60884	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:O00299	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:K7EIH8	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-21259594|ensembl:ENSP00000464756	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:k7eih8_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	ensembl:ENSG00000168259(gene)|ensembl:ENST00000590348(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:/fSmMnrnj/XjslVdpKlrM2w3nqA9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:H3BS86	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-21259582|ensembl:ENSP00000456591	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:h3bs86_human(display_long)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	ensembl:ENSG00000103266(gene)|ensembl:ENST00000567173(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041312	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:kIb5YkvjJXhsREYdDvtNbuGPOdE9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y251	uniprotkb:A4D110	intact:EBI-5453868|uniprotkb:C7F7I4|uniprotkb:Q53GE5|uniprotkb:Q9UL39|uniprotkb:A9JIG7|uniprotkb:C7F7I3|uniprotkb:E9PCA9|uniprotkb:E9PGR1|ensembl:ENSP00000308107|ensembl:ENSP00000384262	intact:EBI-9978194	psi-mi:hpse_human(display_long)|uniprotkb:HPSE(gene name)|psi-mi:HPSE(display_short)|uniprotkb:HEP(gene name synonym)|uniprotkb:HPA(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:HPR1(gene name synonym)|uniprotkb:HPSE1(gene name synonym)|uniprotkb:HSE1(gene name synonym)|uniprotkb:Endo-glucoronidase(gene name synonym)|uniprotkb:Heparanase-1(gene name synonym)	psi-mi:a4d110_human(display_long)|uniprotkb:LOC401309(gene name)|psi-mi:LOC401309(display_short)|uniprotkb:tcag7.949(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260107|imex:IM-26691-147	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092010.1|refseq:NP_001159970.1|refseq:NP_006656.2|refseq:NP_001186759.1|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0030305"(heparanase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045545"(syndecan binding)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0061042"(vascular wound healing)|go:"GO:1904974"(heparanase complex)|interpro:IPR005199(Glycoside hydrolase family 79, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:5E8M|rcsb pdb:5E97|rcsb pdb:5E98|rcsb pdb:5E9B|rcsb pdb:5E9C|rcsb pdb:5L9Y|rcsb pdb:5L9Z|rcsb pdb:5LA4|rcsb pdb:5LA7|rcsb pdb:6ZDM|reactome:R-HSA-2024096|reactome:R-HSA-6798695|ensembl:ENSG00000173083(gene)|ensembl:ENST00000311412(transcript)|ensembl:ENST00000405413(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007160"(cell-matrix adhesion)	interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:MSsqqK+WK2Xy01TEFQbcraZlVXk9606	rogid:RKxCH9JtTeX5LqThR82X/1ohRjM9606	rigid:XDqk4CA/bwGvvpM4LUIBmbUhaYA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95478	uniprotkb:Q96JZ2	intact:EBI-2852366|ensembl:ENSP00000483484	intact:EBI-3919324|intact:EBI-28973686|ensembl:ENSP00000482604|ensembl:ENSP00000483354|uniprotkb:B5ME72|uniprotkb:Q6ZNG7	psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name)	psi-mi:hsh2d_human(display_long)|uniprotkb:HSH2D(gene name)|psi-mi:HSH2D(display_short)|uniprotkb:ALX(gene name synonym)|uniprotkb:Adaptor in lymphocytes of unknown function X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260161|imex:IM-26691-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478	ensembl:ENSP00000483354|ensembl:ENSP00000482604|ensembl:ENSG00000196684(gene)|ensembl:ENST00000613986(transcript)|ensembl:ENST00000616645(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007165"(signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR035047|interpro:IPR036860|rcsb pdb:2CS0|go:"GO:0005737"(cytoplasm)|refseq:NP_116244.1|refseq:NP_001278203.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606	rogid:Y01YjkfU/oOtbz2TdQcnm+lBWhs9606	rigid:IODxLoSGGBSfKi8NSlI1/A5cKAc	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96C10	uniprotkb:Q16666	intact:EBI-744193|uniprotkb:Q9HAM6|ensembl:ENSP00000251642	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809	psi-mi:dhx58_human(display_long)|uniprotkb:Probable ATP-dependent helicase LGP2(gene name synonym)|uniprotkb:Protein D11Lgp2 homolog(gene name synonym)|uniprotkb:DHX58(gene name)|psi-mi:DHX58(display_short)|uniprotkb:D11LGP2E(gene name synonym)|uniprotkb:LGP2(gene name synonym)|uniprotkb:RIG-I-like receptor LGP2(gene name synonym)|uniprotkb:RIG-I-like receptor 3(gene name synonym)	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260170|imex:IM-26691-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077024.2|ensembl:ENSG00000108771(gene)|ensembl:ENST00000251642(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQA|rcsb pdb:2W4R|rcsb pdb:3EQT|reactome:R-HSA-168928|go:"GO:0045824"(negative regulation of innate immune response)|refseq:XP_016880548.1|refseq:XP_016880549.1|dip:DIP-60792N	refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENST00000295809(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042149"(cellular response to glucose starvation)|ensembl:ENSG00000163565(gene)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|reactome:R-HSA-1834941|reactome:R-HSA-3270619	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:CSy2ThXaTTCmqGNqf8LrJvUXIBA9606	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	rigid:MZtN6iPDM3/la/prIWgS8b/hFNM	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:Q9UL15	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:Q9NZT1	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:Q15042	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-1053078|uniprotkb:Q659F5|uniprotkb:Q8TBB4|uniprotkb:C9J837|ensembl:ENSP00000264158|uniprotkb:A6H8Z3	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:rb3gp_human(display_long)|uniprotkb:RAB3 GTPase-activating protein 130 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p130(gene name synonym)|uniprotkb:RAB3GAP1(gene name)|psi-mi:RAB3GAP1(display_short)|uniprotkb:KIAA0066(gene name synonym)|uniprotkb:RAB3GAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	refseq:NP_036365.1|ensembl:ENSG00000115839(gene)|ensembl:ENST00000264158(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060325"(face morphogenesis)|go:"GO:0061646"(positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098794"(postsynapse)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR026147|reactome:R-HSA-6811436|reactome:R-HSA-8876198|refseq:NP_001165906.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:JCtnJX01timbIenQexwG84yBu2I9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:P61626	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-355360|ensembl:ENSP00000261267|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	ensembl:ENSG00000090382(gene)|refseq:NP_000230.1|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:5LVK|rcsb pdb:6LFH|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|ensembl:ENST00000261267(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008152"(metabolic process)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:jydNN9yuU9EYvnth+kv115svRxw9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:P61604	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:P40925	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-709625|uniprotkb:B7Z3I7|uniprotkb:Q6I9V0|uniprotkb:B2R5V5|uniprotkb:B4DUN2|uniprotkb:F5H098|ensembl:ENSP00000233114|ensembl:ENSP00000446395	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:mdhc_human(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:MDH1(gene name)|psi-mi:MDH1(display_short)|uniprotkb:MDHA(gene name synonym)|uniprotkb:Diiodophenylpyruvate reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	refseq:NP_001186040.1|refseq:NP_001186041.1|refseq:NP_005908.1|refseq:NP_001303303.1|ensembl:ENSG00000014641(gene)|ensembl:ENST00000233114(transcript)|ensembl:ENST00000544381(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0047860"(diiodophenylpyruvate reductase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40925|reactome:R-HSA-70263	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:SbY7B81CiCRe8tXpVpSdT1sKGOU9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:P25786	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:H7C0H1	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-21260200|ensembl:ENSP00000394978	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:h7c0h1_human(display_long)|uniprotkb:LHX2(gene name)|psi-mi:LHX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	ensembl:ENSG00000106689(gene)|ensembl:ENST00000446480(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:MgM62/yz2WSLsuEzx9vfaBHyjx09606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:F5GXY2	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-21260188|ensembl:ENSP00000440161	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:f5gxy2_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	ensembl:ENSG00000134333(gene)|ensembl:ENST00000543445(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR036291	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:ySULLS0WS3xCYPBAt4TgsK+OBkM9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H7C1K6	uniprotkb:Q6P5S8	intact:EBI-21260179|ensembl:ENSP00000400784	intact:EBI-6677662	psi-mi:h7c1k6_human(display_long)|uniprotkb:IFI44L(gene name)|psi-mi:IFI44L(display_short)	psi-mi:q6p5s8_human(display_long)|uniprotkb:IGK@(gene name)|psi-mi:IGK@(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260215|imex:IM-26691-83	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137959(gene)|ensembl:ENST00000450498(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR006571(TLDc)|interpro:IPR024644|interpro:IPR027417	rcsb pdb:2NXZ|rcsb pdb:2NY0|rcsb pdb:2NY2|rcsb pdb:2NY4|rcsb pdb:2NY5|rcsb pdb:2NY3|go:"GO:0016020"(membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:2NXY|rcsb pdb:2NY1|rcsb pdb:2NY6|interpro:IPR036179	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lY9SZHcPw7xeHBTXWbR1wLUd3C09606	rogid:QB5zWAe8CmRCxpvKVhbH7O6h56w9606	rigid:AzGAsQkkc+x0jcr1uOXV0cchGp4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14879	uniprotkb:Q9UKX2	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-1049626|uniprotkb:A0AVL4|uniprotkb:Q14322|uniprotkb:Q16229|uniprotkb:Q86T56|ensembl:ENSP00000245503|ensembl:ENSP00000380367|uniprotkb:Q567P6	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:myh2_human(display_long)|uniprotkb:MYH2(gene name)|psi-mi:MYH2(display_short)|uniprotkb:MYHSA2(gene name synonym)|uniprotkb:Myosin heavy chain 2(gene name synonym)|uniprotkb:Myosin heavy chain 2a(gene name synonym)|uniprotkb:Myosin heavy chain IIa(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, adult 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260269|imex:IM-26691-109	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	refseq:NP_001093582.1|refseq:NP_060004.3|ensembl:ENST00000245503(transcript)|ensembl:ENST00000397183(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0032982"(myosin filament)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q9UKX2|reactome:R-HSA-2029482|reactome:R-HSA-9664422|ensembl:ENSG00000125414(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:N23NJxmt8WtUT87k2VPsiB7juqQ9606	rigid:sZ2NDaugvJMSm6wLnCvW90gTtYs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14879	uniprotkb:Q8IXX5	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-2841953|uniprotkb:A8K5W1|uniprotkb:Q6NW15|uniprotkb:Q96E06|ensembl:ENSP00000356211	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:t183a_human(display_long)|uniprotkb:TMEM183A(gene name)|psi-mi:TMEM183A(display_short)|uniprotkb:C1orf37(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260269|imex:IM-26691-109	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	refseq:NP_612400.3|ensembl:ENSG00000163444(gene)|ensembl:ENST00000367242(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026509|interpro:IPR036047|mint:Q8IXX5	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:XNJR0b9RbNBEXSE9ohP+TfVtxzM9606	rigid:sZ2NDaugvJMSm6wLnCvW90gTtYs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14879	uniprotkb:P32322	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260269|imex:IM-26691-109	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606	rigid:sZ2NDaugvJMSm6wLnCvW90gTtYs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14879	uniprotkb:P09914	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-745117|uniprotkb:Q96QM5|intact:EBI-11024988|uniprotkb:B3KS50|uniprotkb:D3DR31|ensembl:ENSP00000360869|uniprotkb:Q5T7J1	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:ifit1_human(display_long)|uniprotkb:Interferon-induced 56 kDa protein(gene name synonym)|uniprotkb:IFIT1(gene name)|psi-mi:IFIT1(display_short)|uniprotkb:G10P1(gene name synonym)|uniprotkb:IFI56(gene name synonym)|uniprotkb:IFNAI1(gene name synonym)|uniprotkb:ISG56(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260269|imex:IM-26691-109	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	refseq:NP_001539.3|refseq:NP_001257857.1|refseq:NP_001257858.1|refseq:NP_001257859.1|ensembl:ENSG00000185745(gene)|ensembl:ENST00000371804(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043657"(host cell)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0071357"(cellular response to type I interferon)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024121|mint:P09914|rcsb pdb:4HOU|rcsb pdb:5UDI|rcsb pdb:5UDJ|rcsb pdb:5UDK|rcsb pdb:5UDL|rcsb pdb:5W5H|rcsb pdb:5W5I|rcsb pdb:6C6K|reactome:R-HSA-1169408|reactome:R-HSA-909733|dip:DIP-37898N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:ANeil+D2pneKAoDFS4Vy97BHu8A9606	rigid:sZ2NDaugvJMSm6wLnCvW90gTtYs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14879	uniprotkb:A0A0G2JIW1	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-21260251|ensembl:ENSP00000387691|ensembl:ENSP00000402651|ensembl:ENSP00000442789	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:a0a0g2jiw1_human(display_long)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260269|imex:IM-26691-109	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	ensembl:ENSG00000212866(gene)|ensembl:ENSG00000224501(gene)|ensembl:ENSG00000232804(gene)|ensembl:ENST00000417199(transcript)|ensembl:ENST00000458062(transcript)|ensembl:ENST00000545241(transcript)|go:"GO:0005524"(ATP binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:5xisCZbIBPDaoXx+UPWc9PdGmI09606	rigid:sZ2NDaugvJMSm6wLnCvW90gTtYs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P20719	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719	-	-	comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:V9GZ41	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260373|ensembl:ENSP00000477398|ensembl:ENSP00000487463	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:v9gz41_human(display_long)|uniprotkb:PCMTD2(gene name)|psi-mi:PCMTD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000203880(gene)|ensembl:ENSG00000280663(gene)|ensembl:ENST00000609372(transcript)|ensembl:ENST00000629502(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:nZLLABgGvPLA926sGAwIkiAfPzI9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9Y5M8	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9Y234	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-727376|uniprotkb:Q4ZFZ1|ensembl:ENSP00000377114|ensembl:ENSP00000377115|ensembl:ENSP00000498546	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:lipt_human(display_long)|uniprotkb:Lipoate-protein ligase(gene name synonym)|uniprotkb:Lipoate biosynthesis protein(gene name synonym)|uniprotkb:Lipoyl ligase(gene name synonym)|uniprotkb:LIPT1(gene name)|psi-mi:LIPT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001191759.1|refseq:NP_057013.1|refseq:NP_660198.1|refseq:NP_660199.1|refseq:NP_660200.1|ensembl:ENSG00000144182(gene)|ensembl:ENST00000393471(transcript)|ensembl:ENST00000393473(transcript)|ensembl:ENST00000651691(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017118"(lipoyltransferase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR004143(Biotin/lipoate A/B protein ligase)|interpro:IPR004562(Lipoyltransferase and lipoate-protein ligase)|reactome:R-HSA-389661	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:OKGFro3bW4qrpHml2H4CtrdGgfc9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9UL15	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9UJS0	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9UII2	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9UI12	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9P035	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9NZ01	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9NQC3	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9BYD3	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099|ensembl:ENSP00000306902	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL4m(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364(gene)|ensembl:ENST00000253099(transcript)|ensembl:ENST00000307422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q9BVK6	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q99653	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q96KA5	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q96K37	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-720094|uniprotkb:Q8NBQ2|uniprotkb:Q96JV7|ensembl:ENSP00000470652	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:s35e1_human(display_long)|uniprotkb:SLC35E1(gene name)|psi-mi:SLC35E1(display_short)|uniprotkb:PSEC0038(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_079157.3|ensembl:ENSG00000127526(gene)|ensembl:ENST00000595753(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004853(Protein of unknown function DUF250)|go:"GO:0015297"(antiporter activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:UelDuXaGT2mBsXghGzSX5aKisj89606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q96D05	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-2548784|ensembl:ENSP00000362376	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q96CS3	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q8WVX9	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q8TAT6	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1994109|uniprotkb:Q8N3J1|uniprotkb:Q9H8V2|uniprotkb:Q9H964|uniprotkb:Q9NWR5|uniprotkb:Q9P229|ensembl:ENSP00000331487	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:npl4_human(display_long)|uniprotkb:NPLOC4(gene name)|psi-mi:NPLOC4(display_short)|uniprotkb:KIAA1499(gene name synonym)|uniprotkb:NPL4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:XP_011523281.1|refseq:NP_060391.2|dip:DIP-44059N|ensembl:ENSG00000182446(gene)|ensembl:ENST00000331134(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036501"(UFD1-NPL4 complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR007716(NPL4, zinc-binding putative)|interpro:IPR007717(NPL4)|interpro:IPR016563(Polyubiquitin-tagged protein recognition complex, Npl4 component)|interpro:IPR024682|interpro:IPR029071|interpro:IPR036443|interpro:IPR037518|mint:Q8TAT6|reactome:R-HSA-110320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:GXRNmG7yqEf5aFMo7yPDih93yfk9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q5TB53	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260364|ensembl:ENSP00000401152	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:q5tb53_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0016021"(integral component of membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensembl:ENSG00000077147(gene)|ensembl:ENST00000443638(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:T1DWVoePJSFkdgudFKdtzv/VaCg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q16795	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q15645	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q15637	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q15386	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q13501	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:Q01650	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_003477.4|ensembl:ENSG00000103257(gene)|ensembl:ENST00000261622(transcript)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070327"(thyroid hormone transport)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904556"(L-tryptophan transmembrane transport)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|go:"GO:0015804"(neutral amino acid transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P62195	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P61968	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N	-	-	crc64:C8AC295144AD7787	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P61619	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P57088	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P55072	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P55036	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P54709	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P53618	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P53597	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P51648	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P50502	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-357285|ensembl:ENSP00000216218|uniprotkb:O14999|uniprotkb:Q2TU77	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:f10a1_human(display_long)|uniprotkb:ST13(gene name)|psi-mi:ST13(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:SNC6(gene name synonym)|uniprotkb:AAG2(gene name synonym)|uniprotkb:Aging-associated protein 2(gene name synonym)|uniprotkb:FAM10A1(gene name synonym)|uniprotkb:Suppression of tumorigenicity 13 protein(gene name synonym)|uniprotkb:Putative tumor suppressor ST13(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:Progesterone receptor-associated p48 protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000100380(gene)|ensembl:ENST00000216218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|mint:P50502|rcsb pdb:1UZS|reactome:R-HSA-3371453|refseq:NP_003923.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:yqG5t4Kuj7ZzfNwlJzGZYscKiM89606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P48047	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P47897	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-347462|uniprotkb:B4DWJ2|ensembl:ENSP00000307567	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:syq_human(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_005042.1|ensembl:ENSG00000172053(gene)|ensembl:ENST00000306125(transcript)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:P47897|rcsb pdb:4R3Z|rcsb pdb:4YE6|rcsb pdb:4YE8|rcsb pdb:4YE9|reactome:R-HSA-2408522|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001259002.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P46379	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P36542	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P28066	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P27824	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P25705	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P25685	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P24539	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P22695	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P18859	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P18085	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P09429	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P08195	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P06576	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P05023	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P04843	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P04233	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:P02786	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O95757	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O95202	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1052895|uniprotkb:Q9UF65|uniprotkb:B4DED2|ensembl:ENSP00000305653	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:letm1_human(display_long)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)|uniprotkb:LETM1(gene name)|psi-mi:LETM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_036450.1|ensembl:ENSG00000168924(gene)|ensembl:ENST00000302787(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042407"(cristae formation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|reactome:R-HSA-8949215|reactome:R-HSA-9013408	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:mDxqXWqmgCjbaZLz4JqteqjDCik9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O75964	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O75947	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O15269	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O15260	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O14980	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:O14828	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:E1NZA1	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21258417	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:C9JU26	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:C9J6N9	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260344|ensembl:ENSP00000418390	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:c9j6n9_human(display_long)|uniprotkb:UFD1(gene name)|psi-mi:UFD1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000070010(gene)|ensembl:ENST00000494054(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:YU/1QUJAWyW8kHeChAhsIDH0U609606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:C9J3R0	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260334|ensembl:ENSP00000405258	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:c9j3r0_human(display_long)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000180198(gene)|ensembl:ENST00000434290(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:9+fGe4T/zhgH2VO1XOSM5OqXdEw9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:B7ZM73	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260321	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:B4E106	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260312	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:b4e106_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR030757|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:uuGPwK8ZAO210iuWpBp+TK7fKNo9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:B2RWN5	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21258368	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9PS44	uniprotkb:B1AJQ6	intact:EBI-21260290|ensembl:ENSP00000432108|ensembl:ENSP00000473544	intact:EBI-21260301|ensembl:ENSP00000392577	psi-mi:e9ps44_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)	psi-mi:b1ajq6_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260385|imex:IM-26691-149	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142089(gene)|ensembl:ENST00000526811(transcript)|ensembl:ENST00000602735(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007593(Interferon-induced transmembrane protein)	ensembl:ENSG00000117758(gene)|ensembl:ENST00000440806(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:bUqZavwPrRyp/JFFxVGk93ihKM09606	rogid:0zq5qvXzoqXybBzDo4meAom6Psc9606	rigid:BbS0VkZNIEzFmyp9Edjq7USPS7s	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14732	uniprotkb:P17931	intact:EBI-725233|uniprotkb:Q9UJT3|uniprotkb:B0YJ29|ensembl:ENSP00000269159	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:impa2_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 2"(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260609|imex:IM-26691-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055029.1|ensembl:ENSG00000141401(gene)|ensembl:ENST00000269159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rigid:HZmK7coAZMJ5ZP/FqEXto7kAnVs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14732	uniprotkb:P13797	intact:EBI-725233|uniprotkb:Q9UJT3|uniprotkb:B0YJ29|ensembl:ENSP00000269159	intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339	psi-mi:impa2_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 2"(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)	psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260609|imex:IM-26691-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055029.1|ensembl:ENSG00000141401(gene)|ensembl:ENST00000269159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183	refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606	rigid:HZmK7coAZMJ5ZP/FqEXto7kAnVs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14732	uniprotkb:O14639	intact:EBI-725233|uniprotkb:Q9UJT3|uniprotkb:B0YJ29|ensembl:ENSP00000269159	intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895	psi-mi:impa2_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 2"(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)	psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260609|imex:IM-26691-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055029.1|ensembl:ENSG00000141401(gene)|ensembl:ENST00000269159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183	refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606	rigid:HZmK7coAZMJ5ZP/FqEXto7kAnVs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O14732	uniprotkb:H6VRG2	intact:EBI-725233|uniprotkb:Q9UJT3|uniprotkb:B0YJ29|ensembl:ENSP00000269159	intact:EBI-21258937	psi-mi:impa2_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 2"(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)	psi-mi:h6vrg2_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:Keratin, type II cytoskeletal 1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260609|imex:IM-26691-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055029.1|ensembl:ENSG00000141401(gene)|ensembl:ENST00000269159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183	go:"GO:0005886"(plasma membrane)|go:"GO:0045095"(keratin filament)|interpro:IPR018039|interpro:IPR039008|interpro:IPR032449|interpro:IPR032444|interpro:IPR003054(Type II keratin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:PLuY4SY5eKZ1V/E2+/aEfMHIF9s9606	rigid:HZmK7coAZMJ5ZP/FqEXto7kAnVs	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9UQ80	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P35250	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P35244	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P27694	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9Y5Z7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9Y5B9	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9UNS2	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9P2R7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9NSE4	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9H444	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9H1B7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-2130145|uniprotkb:Q8NDQ2|uniprotkb:Q96JG2|uniprotkb:Q9H3I7|intact:EBI-28987945|ensembl:ENSP00000238647	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:i2bpl_human(display_long)|uniprotkb:IRF2BPL(gene name)|psi-mi:IRF2BPL(display_short)|uniprotkb:C14orf4(gene name synonym)|uniprotkb:KIAA1865(gene name synonym)|uniprotkb:My039(orf name)|uniprotkb:EAP1(gene name synonym)|uniprotkb:Enhanced at puberty protein 1(gene name synonym)|uniprotkb:Interferon regulatory factor 2-binding protein-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_078772.1|ensembl:ENSP00000238647|ensembl:ENSG00000119669(gene)|ensembl:ENST00000238647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046543"(development of secondary female sexual characteristics)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR022750|interpro:IPR044882|rcsb pdb:2B9G|rcsb pdb:2CS3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:Am6HBI/kGwqskhr3163mVz+3Bdk9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9C005	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q9BXW7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-4399500|uniprotkb:B2RCK5|uniprotkb:Q9BXW8|uniprotkb:Q9NWA8|uniprotkb:Q9NX41|ensembl:ENSP00000337358	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:hdhd5_human(display_long)|uniprotkb:HDHD5(gene name)|psi-mi:HDHD5(display_short)|uniprotkb:CECR5(gene name synonym)|uniprotkb:Cat eye syndrome critical region protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_060299.4|refseq:NP_149061.1|ensembl:ENSG00000069998(gene)|ensembl:ENST00000336737(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|interpro:IPR006353(HAD-superfamily hydrolase, subfamily IIA, CECR5)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR029621|interpro:IPR036412|mint:Q9BXW7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:INkCPE3PGW5PVO8j4245B1F99HU9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q96T60	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1045072|uniprotkb:Q9P1V2|uniprotkb:Q9UKU8|uniprotkb:Q9UNF8|uniprotkb:Q9UNI0|ensembl:ENSP00000323511|ensembl:ENSP00000472300|uniprotkb:Q9BUL2	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:pnkp_human(display_long)|uniprotkb:Polynucleotide kinase-3'-phosphatase(gene name synonym)|uniprotkb:DNA 5'-kinase/3'-phosphatase(gene name synonym)|uniprotkb:PNKP(gene name)|psi-mi:PNKP(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000039650(gene)|ensembl:ENST00000322344(transcript)|ensembl:ENST00000596014(transcript)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009314"(response to radiation)|go:"GO:0000718"(nucleotide-excision repair, DNA damage removal)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0035861"(site of double-strand break)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046404"(polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|go:"GO:0046939"(nucleotide phosphorylation)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR006550(Polynucleotide kinase 3-phosphatase)|interpro:IPR006551(DNA 3-phosphatase)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013954(Polynucleotide kinase 3 phosphatase, central region)|interpro:IPR023214|interpro:IPR027417|interpro:IPR036412|interpro:IPR041388|mint:Q96T60|rcsb pdb:2BRF|rcsb pdb:2W3O|reactome:R-HSA-5649702|refseq:NP_009185.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:wlLm6ja4qrCmWB44mE+C4w3wnyQ9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q96CT7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-5461329|ensembl:ENSP00000408730|ensembl:ENSP00000471455	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:cc124_human(display_long)|uniprotkb:CCDC124(gene name)|psi-mi:CCDC124(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001129675.1|refseq:NP_612451.1|ensembl:ENSG00000007080(gene)|ensembl:ENST00000445755(transcript)|ensembl:ENST00000597436(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR010422(Protein of unknown function DUF1014)|mint:Q96CT7|rcsb pdb:6Z6L|rcsb pdb:6ZM7|rcsb pdb:6ZME	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:w3LqsScVHWABZgIwYZXS6Ly9CiM9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q96C36	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q92615	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8WZ42	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8WWC4	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8NI60	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8NC56	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8IV63	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1058605|uniprotkb:Q502Y2|uniprotkb:Q9P2V8|uniprotkb:A8KA53|intact:EBI-1795523|uniprotkb:A6NEG5|ensembl:ENSP00000324636|ensembl:ENSP00000469880|ensembl:ENSP00000473171	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:vrk3_human(display_long)|uniprotkb:VRK3(gene name)|psi-mi:VRK3(display_short)|uniprotkb:Vaccinia-related kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001295349.1|refseq:NP_057524.3|refseq:NP_001020949.1|ensembl:ENSG00000105053(gene)|ensembl:ENST00000316763(transcript)|ensembl:ENST00000594948(transcript)|ensembl:ENST00000599538(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026870|rcsb pdb:2JII|reactome:R-HSA-202670|refseq:XP_005259028.1|refseq:XP_005259029.1|refseq:XP_006723300.1|refseq:XP_006723301.1|refseq:XP_011525325.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:eoBtIgSkVcOE5bw/By6UEqbiO/I9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q8IU81	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-6115514|uniprotkb:Q53EL7|uniprotkb:Q6DC95|uniprotkb:Q9BRZ9|uniprotkb:Q9Y4P4|ensembl:ENSP00000307265	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:i2bp1_human(display_long)|uniprotkb:IRF2BP1(gene name)|psi-mi:IRF2BP1(display_short)|uniprotkb:Probable E3 ubiquitin-protein ligase IRF2BP1(gene name synonym)|uniprotkb:Probable RING-type E3 ubiquitin transferase IRF2BP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_056464.1|ensembl:ENSG00000170604(gene)|ensembl:ENST00000302165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR018957|interpro:IPR022750|interpro:IPR044882|mint:Q8IU81	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:0ooWsKsxvLQtWbTA3FsVfO+6TBA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q86UE4	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1046588|ensembl:ENSP00000338235|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|uniprotkb:Q05DH2|uniprotkb:Q52QU9	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000147649(gene)|ensembl:ENST00000336273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q7Z5L9	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-2857769|uniprotkb:B1AM36|uniprotkb:Q7Z5L8|uniprotkb:Q6P083|uniprotkb:Q8N351|uniprotkb:B1AM35|uniprotkb:Q8WUH8|ensembl:ENSP00000355568	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:i2bp2_human(display_long)|uniprotkb:IRF2BP2(gene name)|psi-mi:IRF2BP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001070865.1|refseq:NP_892017.2|ensembl:ENSG00000168264(gene)|ensembl:ENST00000366609(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR022750|interpro:IPR044882	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:D7vDkesEqSEgGURqQ0LM7XhXdRk9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q6PGP7	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-6083436|uniprotkb:O15077|uniprotkb:Q6PJI3|ensembl:ENSP00000351596|ensembl:ENSP00000497948	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:ttc37_human(display_long)|uniprotkb:Tricho-hepatic-enteric syndrome protein(gene name synonym)|uniprotkb:SKI3 homolog(gene name synonym)|uniprotkb:TTC37(gene name)|psi-mi:TTC37(display_short)|uniprotkb:KIAA0372(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_055454.1|ensembl:ENSG00000198677(gene)|ensembl:ENST00000358746(transcript)|ensembl:ENST00000649566(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0035327"|go:"GO:0055087"(Ski complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|mint:Q6PGP7|reactome:R-HSA-429958	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:1vbt+NR8Vmwq7a+9fisoF2WxDbc9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q5SW79	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q5JTZ9	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q3MHD2	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q16778	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1056125|uniprotkb:A3KMC7|uniprotkb:Q4KMY1|uniprotkb:Q5QNX0|uniprotkb:Q9UE88|uniprotkb:A8K110|ensembl:ENSP00000358151	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:h2b2e_human(display_long)|uniprotkb:H2BC21(gene name)|psi-mi:H2BC21(display_short)|uniprotkb:H2B-clustered histone 21(gene name synonym)|uniprotkb:H2BFQ(gene name synonym)|uniprotkb:HIST2H2BE(gene name synonym)|uniprotkb:Histone H2B-GL105(gene name synonym)|uniprotkb:Histone H2B.q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003519.1|ensembl:ENSG00000184678(gene)|ensembl:ENST00000369155(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16778|rcsb pdb:4NFT|rcsb pdb:6A7U|rcsb pdb:6KBB|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:7BXT|dip:DIP-39324N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:jh5U2ATjpAVt5DYOgr9YbcVdEzw9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q15477	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-373226|uniprotkb:O15005|uniprotkb:Q12902|uniprotkb:Q15476|intact:EBI-1058949|uniprotkb:Q5ST66|ensembl:ENSP00000364543|ensembl:ENSP00000372827|ensembl:ENSP00000394400|ensembl:ENSP00000399530|ensembl:ENSP00000400626|ensembl:ENSP00000412310	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:skiv2_human(display_long)|uniprotkb:SKIV2L(gene name)|psi-mi:SKIV2L(display_short)|uniprotkb:DDX13(gene name synonym)|uniprotkb:SKI2W(gene name synonym)|uniprotkb:SKIV2(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:Helicase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_008860.4|ensembl:ENSG00000204351(gene)|ensembl:ENSG00000206353(gene)|ensembl:ENSG00000223493(gene)|ensembl:ENSG00000225737(gene)|ensembl:ENSG00000228896(gene)|ensembl:ENSG00000232616(gene)|ensembl:ENST00000375394(transcript)|ensembl:ENST00000383336(transcript)|ensembl:ENST00000412823(transcript)|ensembl:ENST00000421789(transcript)|ensembl:ENST00000429465(transcript)|ensembl:ENST00000448219(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|interpro:IPR040801|mint:Q15477|reactome:R-HSA-390471|reactome:R-HSA-429958	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:+42a3/XPqsM8hc3qP2M9n/pZ+bY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q15291	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q14258	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q13283	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q08380	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q04837	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q03164	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:Q00059	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P62891	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P62861	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-358093|uniprotkb:Q05472|uniprotkb:Q95261|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rs30_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short)|uniprotkb:Small ribosomal subunit protein eS30(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR006846(Ribosomal protein S30)|mint:P62861|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:mfW+tko85h9ZOK7wNXUsYiYY3Hc9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P54198	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P51610	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P50402	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P49916	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1753381|intact:EBI-1058758|uniprotkb:Q16714|uniprotkb:Q6NVK3|ensembl:ENSP00000367787|uniprotkb:E5KLB5|uniprotkb:E5KLB6	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:dnli3_human(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_002302.2|refseq:NP_039269.2|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070421"(DNA ligase III-XRCC1 complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|mint:P49916|rcsb pdb:1IMO|rcsb pdb:1IN1|rcsb pdb:1UW0|rcsb pdb:3L2P|rcsb pdb:3PC7|rcsb pdb:3PC8|rcsb pdb:3QVG|rcsb pdb:6WH1|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006288"(base-excision repair, DNA ligation)|go:"GO:0006302"(double-strand break repair)|refseq:XP_016880113.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P49458	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P49411	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P48735	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P42166	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P39880	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P30042	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P18887	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P17980	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P13010	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P12956	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P09874	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P08758	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P08243	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P07737	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P06733	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P06493	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:P05386	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:O75306	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:O43837	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:H6VRG2	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-21258937	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:h6vrg2_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:Keratin, type II cytoskeletal 1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	go:"GO:0005886"(plasma membrane)|go:"GO:0045095"(keratin filament)|interpro:IPR018039|interpro:IPR039008|interpro:IPR032449|interpro:IPR032444|interpro:IPR003054(Type II keratin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:PLuY4SY5eKZ1V/E2+/aEfMHIF9s9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:F5GXY2	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-21260188|ensembl:ENSP00000440161	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:f5gxy2_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000134333(gene)|ensembl:ENST00000543445(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR036291	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:ySULLS0WS3xCYPBAt4TgsK+OBkM9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:A8MXV4	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-11350801|ensembl:ENSP00000380251	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:nud19_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 19(gene name synonym)|uniprotkb:NUDT19(gene name)|psi-mi:NUDT19(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001099040.1|ensembl:ENSG00000213965(gene)|ensembl:ENST00000397061(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0010945"(CoA pyrophosphatase activity)|go:"GO:0015938"(coenzyme A catabolic process)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0044580"(butyryl-CoA catabolic process)|go:"GO:1901289"(succinyl-CoA catabolic process)|go:"GO:1902858"(propionyl-CoA metabolic process)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR039121|reactome:R-HSA-390918|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:nSyCFhGmUMc1wbmmLp6RZvUojaM9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:A4D1E9	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-5453796|uniprotkb:B4DFY6|uniprotkb:Q3B7A6|uniprotkb:Q5H9V2|uniprotkb:Q8IXG8|uniprotkb:Q8N982|uniprotkb:Q8WU16|uniprotkb:Q9BSP1|uniprotkb:Q9Y6T6|ensembl:ENSP00000222511	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:gtpba_human(display_long)|uniprotkb:GTPBP10(gene name)|psi-mi:GTPBP10(display_short)|uniprotkb:OBGH2(gene name synonym)|uniprotkb:Protein obg homolog 2(gene name synonym)|uniprotkb:UG0751c10(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	refseq:NP_001036182.1|refseq:NP_149098.2|ensembl:ENSG00000105793(gene)|ensembl:ENST00000222511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006169(GTP1/OBG subdomain)|interpro:IPR027417|interpro:IPR031167|interpro:IPR035101|interpro:IPR036726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:rxJN6IWcF54XIXy3AvOt9JN9m/U9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14316	uniprotkb:A3KMH1	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260627|imex:IM-26691-183	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	rigid:B2xKfyiSauFu9pjNfNrxw75DPb0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q9UNQ2	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-395738|uniprotkb:O76025|uniprotkb:Q9BU77|uniprotkb:Q9UES1|ensembl:ENSP00000199320	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:dim1_human(display_long)|uniprotkb:DIMT1L(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1 homolog(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1-like(gene name synonym)|uniprotkb:HUSSY-05(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:DIMT1(gene name)|psi-mi:DIMT1(display_short)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_055288.1|ensembl:ENSG00000086189(gene)|ensembl:ENST00000199320(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063|mint:Q9UNQ2|rcsb pdb:1ZQ9|rcsb pdb:6W6C|rcsb pdb:6W6F|reactome:R-HSA-6790901|refseq:NP_001335005.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:hx0FRrx+XTeoziOqfesiw4KL+wo9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q9UN37	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q9UBS4	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q9BVS5	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-3197877|ensembl:ENSP00000302801|uniprotkb:Q9H0Q9|uniprotkb:Q9NWS7	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tr61b_human(display_long)|uniprotkb:TRMT61B(gene name)|psi-mi:TRMT61B(display_short)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	ensembl:ENSG00000171103(gene)|ensembl:ENST00000306108(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0016433"("rRNA (adenine) methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0080009"(mRNA methylation)|interpro:IPR014816(tRNA methyltransferase complex GCD14 subunit)|interpro:IPR029063|rcsb pdb:2B25|reactome:R-HSA-6787450|refseq:NP_060380.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:Y6HxpgK8LkWJSC3diZfPc302JV49606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q9BQE3	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q99832	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q15029	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q14204	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001367.2|ensembl:ENSP00000348965|ensembl:ENSG00000197102(gene)|ensembl:ENST00000360184(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|mint:Q14204|rcsb pdb:2BOR|rcsb pdb:2BOT|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-37544N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q13885	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q13509	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:Q13112	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P78371	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P53618	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P52789	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-741469|uniprotkb:Q8WU87|uniprotkb:Q9UN82|ensembl:ENSP00000290573|uniprotkb:D6W5J2	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:hxk2_human(display_long)|uniprotkb:Hexokinase type II(gene name synonym)|uniprotkb:Muscle form hexokinase(gene name synonym)|uniprotkb:HK2(gene name)|psi-mi:HK2(display_short)|uniprotkb:Hexokinase-B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P52789|rcsb pdb:2NZT|rcsb pdb:5HEX|rcsb pdb:5HFU|rcsb pdb:5HG1|reactome:R-HSA-70171|go:"GO:0008865"(fructokinase activity)|ensembl:ENSG00000159399(gene)|ensembl:ENST00000290573(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|refseq:NP_000180.2|dip:DIP-50110N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:99w5KbKmsqMoorQz/wot6z6t2WM9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P52292	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P50991	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P50990	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P49368	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P49327	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P48643	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P47897	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-347462|uniprotkb:B4DWJ2|ensembl:ENSP00000307567	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:syq_human(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_005042.1|ensembl:ENSG00000172053(gene)|ensembl:ENST00000306125(transcript)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:P47897|rcsb pdb:4R3Z|rcsb pdb:4YE6|rcsb pdb:4YE8|rcsb pdb:4YE9|reactome:R-HSA-2408522|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001259002.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P46821	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P40227	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P28340	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P27708	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P17987	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:P04049	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:E9PSE3	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-21260837|ensembl:ENSP00000488372	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:e9pse3_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	ensembl:ENSG00000276561(gene)|ensembl:ENST00000631879(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:BpnS/2CnzdWZyGvD5KPyq9OltAA9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92985	uniprotkb:C9J4M6	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21260857|imex:IM-26691-121	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	rigid:8VU4fXqbKs/nsN8jBbydmZrh0GE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UQ80	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P15927	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P42702	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-7702162|ensembl:ENSP00000263409|ensembl:ENSP00000398368|uniprotkb:Q6LCD9|intact:MINT-1352123	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:lifr_human(display_long)|uniprotkb:LIFR(gene name)|psi-mi:LIFR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:XP_016864952.1|ensembl:ENSG00000113594(gene)|ensembl:ENST00000263409(transcript)|ensembl:ENST00000453190(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040817|interpro:IPR040901|rcsb pdb:3E0G|reactome:R-HSA-6788467|reactome:R-HSA-8939247|refseq:XP_011512342.1|refseq:XP_011512344.1|refseq:NP_001121143.1|refseq:NP_002301.1|dip:DIP-5770N	-	-	comment:mint|function:Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells|function:"Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS) [MIM:601559]; also called Schwartz-Jampel syndrome type 2 or SJS2. SWS is a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias. SWS is characterized by bowing of the lower limbs, with internal cortical thickening, wide metaphyses with abnormal trabecular pattern, and camptodactyly. Additional features include feeding and swallowing difficulties, as well as respiratory distress and hyperthermic episodes, which cause death in the first months of life. The rare survivors develop progressive scoliosis, spontaneous fractures, bowing of the lower limbs, with prominent joints and dysautonomia symptoms, including temperature instability, absent corneal and patellar reflexes, and smooth tongue"|function:"A chromosomal rearrangement involving LIFR may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(5;8)(p13;q12) with PLAG1"	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:kteW2gF4cZU5b5JOkszDFWsgyN89606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9Y6I3	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-713198|intact:EBI-28967658|ensembl:ENSP00000270460|uniprotkb:Q86ST3|uniprotkb:Q9HA18	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:epn1_human(display_long)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)|uniprotkb:EH domain-binding mitotic phosphoprotein(gene name synonym)|uniprotkb:EPN1(gene name)|psi-mi:EPN1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048568"(embryonic organ development)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q9Y6I3|rcsb pdb:1INZ|rcsb pdb:1KYD|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000063245(gene)|ensembl:ENST00000270460(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|ensembl:ENST00000085079|ensembl:ENSP00000085079|ensembl:ENSP00000270460|ensembl:ENST00000411543|ensembl:ENSP00000406209|refseq:NP_001123543.1|refseq:NP_001123544.1|refseq:NP_037465.2|refseq:XP_005258886.1|refseq:XP_016882211.1|refseq:XP_011525183.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:mp6MIJYGUJryy3Lk5coFqvOt55c9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9Y520	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_055987.2|refseq:XP_006711301.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|ensembl:ENST00000338920|ensembl:ENSP00000343629|ensembl:ENSG00000117523|ensembl:ENST00000426496|ensembl:ENSP00000410219|ensembl:ENST00000647382|ensembl:ENSP00000495867|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9Y281	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9Y224	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1104547|ensembl:ENSP00000261700	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UPQ0	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|ensembl:ENSG00000064042(gene)|ensembl:ENST00000313860(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029980|interpro:IPR031865|interpro:IPR036872|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UN86	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UKS6	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UJC5	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1171099|uniprotkb:Q9BPY5|uniprotkb:A8MQU2|uniprotkb:Q2VPC2|uniprotkb:Q5VV96|uniprotkb:Q6NSK8|uniprotkb:Q6P9E8|uniprotkb:Q7Z734|uniprotkb:Q8IWD3|ensembl:ENSP00000358853	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:sh3l2_human(display_long)|uniprotkb:SH3BGRL2(gene name)|psi-mi:SH3BGRL2(display_short)|uniprotkb:FASH3(gene name synonym)|uniprotkb:Fovea-associated SH3 domain-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_113657.1|ensembl:ENSG00000198478(gene)|ensembl:ENST00000369838(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031965"(nuclear membrane)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|rcsb pdb:2CT6|refseq:XP_016866833.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:lCYjqL/j1o+rDCdHKSOZHNXTcsU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9UG63	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9NYZ3	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2511327|intact:EBI-28974182|ensembl:ENSP00000415430|uniprotkb:Q9BRE0|uniprotkb:Q53GX5|uniprotkb:Q20WK2|uniprotkb:Q9UGZ9|uniprotkb:Q6DHX4|uniprotkb:Q5R3I6|uniprotkb:Q9Y557|uniprotkb:B0QYM3	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:gtse1_human(display_long)|uniprotkb:GTSE1(gene name)|psi-mi:GTSE1(display_short)|uniprotkb:Protein B99 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000075218(gene)|ensembl:ENST00000454366(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|interpro:IPR026657|interpro:IPR026659|interpro:IPR032768|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-69481|reactome:R-HSA-8852276|ensembl:ENSP00000415430|refseq:NP_057510.4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:3vSRRbx11yGNbuaniX7ZtqE/cLI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9NY93	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-372376|uniprotkb:Q9H9I8|intact:EBI-1051948|uniprotkb:Q6IAE2|uniprotkb:A4D2K9|ensembl:ENSP00000258772|uniprotkb:C9JV95	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ddx56_human(display_long)|uniprotkb:DDX56(gene name)|psi-mi:DDX56(display_short)|uniprotkb:DDX21(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:NOH61(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_061955.1|ensembl:ENSG00000136271(gene)|ensembl:ENST00000258772(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NY93|refseq:NP_001244118.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:Pfa1hEJ7HnBZtSO4aZ2xRixpldc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9NSD9	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5|ensembl:ENSP00000281828	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|ensembl:ENSG00000116120(gene)|ensembl:ENST00000281828(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:XP_016858599.1|dip:DIP-32869N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9H7B2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9H6S0	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1057466|uniprotkb:B2RP66|ensembl:ENSP00000161863	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ytdc2_human(display_long)|uniprotkb:YTHDC2(gene name)|psi-mi:YTHDC2(display_short)|uniprotkb:YTH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_073739.3|ensembl:ENSG00000047188(gene)|ensembl:ENST00000161863(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007286"(spermatid development)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048599"(oocyte development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051729"(germline cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031083|interpro:IPR034083|interpro:IPR036770|interpro:IPR036867|mint:Q9H6S0|rcsb pdb:2YU6|rcsb pdb:6K6U|refseq:XP_016865219.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:8J8b1Q3F6rfXUwtp7EOeU2y89Lc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9BZF9	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9BSJ8	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q9BR76	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q99613	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q99459	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q96ST2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2515615|ensembl:ENSP00000295321|uniprotkb:Q2TB65|uniprotkb:Q9NV97|uniprotkb:Q96MI7|uniprotkb:Q9NWH8|uniprotkb:Q6P157|uniprotkb:Q8N3E8	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:iws1_human(display_long)|uniprotkb:IWS1(gene name)|psi-mi:IWS1(display_short)|uniprotkb:IWS1L(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000163166(gene)|ensembl:ENST00000295321(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0090239"(regulation of histone H4 acetylation)|go:"GO:2001253"(regulation of histone H3-K36 trimethylation)|interpro:IPR017923|interpro:IPR035441|mint:Q96ST2|rcsb pdb:6EMR|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|refseq:NP_060439.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:G7KjbkwlfWdg2VufnJfRBiS/yUs9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q96IZ0	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-595869|uniprotkb:O75796|uniprotkb:Q6FHY9|uniprotkb:Q8N700|intact:EBI-2561293|ensembl:ENSP00000328088	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:pawr_human(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:PAWR(gene name)|psi-mi:PAWR(display_short)|uniprotkb:PAR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_002574.2|refseq:XP_016874866.1|refseq:XP_006719498.1|dip:DIP-29003N|ensembl:ENSG00000177425(gene)|ensembl:ENST00000328827(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR026117|rcsb pdb:2JK9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid://McqfeFZjywd7Ew+WWk0eCzfNw9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q96D71	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q96CW1	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q96CT7	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-5461329|ensembl:ENSP00000408730|ensembl:ENSP00000471455	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cc124_human(display_long)|uniprotkb:CCDC124(gene name)|psi-mi:CCDC124(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001129675.1|refseq:NP_612451.1|ensembl:ENSG00000007080(gene)|ensembl:ENST00000445755(transcript)|ensembl:ENST00000597436(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR010422(Protein of unknown function DUF1014)|mint:Q96CT7|rcsb pdb:6Z6L|rcsb pdb:6ZM7|rcsb pdb:6ZME	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:w3LqsScVHWABZgIwYZXS6Ly9CiM9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q8WWI1	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-350367|uniprotkb:O15462|uniprotkb:O95346|uniprotkb:Q9UKC1|uniprotkb:Q9UQM5|uniprotkb:Q9Y6A7|uniprotkb:Q5TBK6|uniprotkb:E9PLH4	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:lmo7_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)|uniprotkb:FBX20(gene name synonym)|uniprotkb:FBXO20(gene name synonym)|uniprotkb:KIAA0858(gene name synonym)|uniprotkb:F-box only protein 20(gene name synonym)|uniprotkb:LOMP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005349.3|refseq:NP_056667.2|refseq:NP_001293009.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0000151"(ubiquitin ligase complex)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003096(SM22/calponin)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872|rcsb pdb:2EAQ|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENST00000341547|ensembl:ENSP00000342112|ensembl:ENSG00000136153|refseq:NP_001317512.1|mint:Q8WWI1|dip:DIP-33107N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:d8c3oZaqaloIUBqxgvpNI3PP2fU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q8N9B5	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-866435|uniprotkb:B5MDS2|uniprotkb:B5MDT0|uniprotkb:A1L4P5|intact:EBI-28978750|ensembl:ENSP00000379441	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:jmy_human(display_long)|uniprotkb:JMY(gene name)|psi-mi:JMY(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_689618.4|ensembl:ENSP00000379441|ensembl:ENSG00000152409(gene)|ensembl:ENST00000396137(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031252"(cell leading edge)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070060"('de novo' actin filament nucleation)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR031738|interpro:IPR031808|interpro:IPR033324|mint:Q8N9B5|reactome:R-HSA-6804760	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:ZmZQs2wnJPgKfxInVbLeefZFUTg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q7Z478	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-719925|uniprotkb:O75549|uniprotkb:Q63HN0|uniprotkb:Q63HN3|uniprotkb:Q8IWW2|uniprotkb:Q8N3A1|uniprotkb:Q9UMH2|intact:EBI-28967230|ensembl:ENSP00000251636	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:dhx29_human(display_long)|uniprotkb:DEAH box protein 29(gene name synonym)|uniprotkb:Nucleic acid helicase DDXx(gene name synonym)|uniprotkb:DHX29(gene name)|psi-mi:DHX29(display_short)|uniprotkb:DDX29(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSP00000251636|refseq:NP_061903.2|ensembl:ENSG00000067248(gene)|ensembl:ENST00000251636(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR034730|refseq:NP_001332893.1|refseq:NP_001332894.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:T78lwkAmdyEefThCR1zDrVbTBYE9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q7L014	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2555356|uniprotkb:Q96EI0|uniprotkb:O94894|uniprotkb:Q9Y658|ensembl:ENSP00000346236	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ddx46_human(display_long)|uniprotkb:KIAA0801(gene name synonym)|uniprotkb:DEAD box protein 46(gene name synonym)|uniprotkb:PRP5 homolog(gene name synonym)|uniprotkb:DDX46(gene name)|psi-mi:DDX46(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_055644.2|ensembl:ENSG00000145833(gene)|ensembl:ENST00000354283(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q7L014|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|reactome:R-HSA-72163|refseq:NP_001287789.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:spn1NOUIO6XjH4RRbtPsBgR5Wk09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q7KZF4	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q6NZI2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2559016|uniprotkb:O00535|uniprotkb:Q96H74|uniprotkb:Q6GMY1|uniprotkb:B2RAW7|uniprotkb:Q9BT85|uniprotkb:Q9HAP4|ensembl:ENSP00000349541	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cavn1_human(display_long)|uniprotkb:CAVIN1(gene name)|psi-mi:CAVIN1(display_short)|uniprotkb:Cavin-1(gene name synonym)|uniprotkb:PTRF(gene name synonym)|uniprotkb:Polymerase I and transcript release factor(gene name synonym)|uniprotkb:FKSG13(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_036364.2|ensembl:ENSG00000177469(gene)|ensembl:ENST00000357037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009306"(protein secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR026752|mint:Q6NZI2|reactome:R-HSA-73863|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|interpro:IPR033297|dip:DIP-48550N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:55dzpwSSfj8aEzmgHKYdrHfgYBg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q63HR1	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2559239	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:q63hr1_human(display_long)|uniprotkb:DKFZp686P17171(gene name)|psi-mi:DKFZp686P17171(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	interpro:IPR006861(Hyaluronan/mRNA binding protein)|refseq:NP_056455.3|interpro:IPR032381|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR027205|interpro:IPR039764	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:f49rbKRg8Pj11WueAwQL26dSELc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q5W012	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21258084|ensembl:ENSP00000395448	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:q5w012_human(display_long)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000134453(gene)|ensembl:ENST00000437845(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR040052	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:61YxKA3gAuN6QCpAFyBysWjmYX89606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q5JWF2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-4400880|uniprotkb:A2A2S3|uniprotkb:E1P5G3|uniprotkb:O75684|uniprotkb:O75685|uniprotkb:Q5JW67|uniprotkb:Q5JWF1|uniprotkb:Q9NY42|ensembl:ENSP00000360141	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:gnas1_human(display_long)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Extra large alphas protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001296812.1|refseq:NP_536350.2|refseq:XP_016883302.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371100(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0060348"(bone development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q5JWF2|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:UmsO2DSEM3LmGMPwxSdkmlrKMLc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q16698	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2554876|uniprotkb:B7Z6B8|uniprotkb:Q93085|uniprotkb:Q2M304|ensembl:ENSP00000220764|intact:EBI-10969978	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:decr_human(display_long)|uniprotkb:DECR(gene name synonym)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)|uniprotkb:DECR1(gene name)|psi-mi:DECR1(display_short)|uniprotkb:SDR18C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 18C member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001350.1|ensembl:ENSG00000104325(gene)|ensembl:ENST00000220764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:Q16698|rcsb pdb:1W6U|rcsb pdb:1W73|rcsb pdb:1W8D|reactome:R-HSA-77288|interpro:IPR036291|refseq:NP_001317504.1|refseq:XP_016868636.1|refseq:XP_016868637.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:l/8jxdd4pqUIUV2eIThvXTd66yE9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q15397	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q15046	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14839	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14694	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2510389|uniprotkb:B4DS84|uniprotkb:B2RDJ8|uniprotkb:Q9BWG7|uniprotkb:Q9NSL7|ensembl:ENSP00000219473	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ubp10_human(display_long)|uniprotkb:USP10(gene name)|psi-mi:USP10(display_short)|uniprotkb:KIAA0190(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005144.2|ensembl:ENSP00000219473|ensembl:ENST00000570191|ensembl:ENSP00000457411|refseq:NP_001259004.1|ensembl:ENSG00000103194(gene)|ensembl:ENST00000219473(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR018200|interpro:IPR028767|interpro:IPR028889|interpro:IPR038765|mint:Q14694|reactome:R-HSA-5656169|reactome:R-HSA-5689880|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:W34ZdOIilLOVI8SXqCH3rOmmloo9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14677	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSP00000388340|ensembl:ENST00000523094|ensembl:ENSP00000429345|ensembl:ENST00000523908|ensembl:ENSP00000429824|ensembl:ENST00000530742|ensembl:ENSP00000433419|refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|ensembl:ENSG00000113282(gene)|ensembl:ENST00000411809(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722|dip:DIP-45604N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14558	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-724449|uniprotkb:Q96H06|uniprotkb:B2R6M4	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:kpra_human(display_long)|uniprotkb:39 kDa phosphoribosypyrophosphate synthase-associated protein(gene name synonym)|uniprotkb:PRPSAP1(gene name)|psi-mi:PRPSAP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_002757.2|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|rcsb pdb:2C4K|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR029057|interpro:IPR029099	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:7kFJX6q/3EcGnRNgAOImlr93Xys9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14444	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14160	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14157	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q14152	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q13561	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:JrL5jUtArek+zqmCkPKomnjuSf09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q13442	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q13283	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q12965	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q12904	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1045802|uniprotkb:Q6FG28|uniprotkb:Q96CQ9|uniprotkb:B4E1S7|uniprotkb:B3KTR2|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:aimp1_human(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001135887.1|refseq:NP_001135888.1|refseq:NP_004748.2|ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q12904|rcsb pdb:1E7Z|rcsb pdb:1EUJ|rcsb pdb:1FL0|rcsb pdb:4R3Z|reactome:R-HSA-2408522|reactome:R-HSA-379716|refseq:XP_016864324.1|refseq:XP_016864325.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q08J23	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q08945	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:Q01082	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P98179	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2949699|ensembl:ENSP00000365946|ensembl:ENSP00000365950	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:rbm3_human(display_long)|uniprotkb:RBM3(gene name)|psi-mi:RBM3(display_short)|uniprotkb:RNPL(gene name synonym)|uniprotkb:RNA-binding motif protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0030425"(dendrite)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:P98179|go:"GO:0006417"(regulation of translation)|ensembl:ENSG00000102317(gene)|ensembl:ENST00000376755(transcript)|ensembl:ENST00000376759(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_006734.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:+KPnDlgXy+KGVDjTilKMXb5dJGs9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P80723	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P78347	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P62854	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P61981	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P53675	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-358826|uniprotkb:Q14017|uniprotkb:Q15808|uniprotkb:Q15809|uniprotkb:B7Z7U5|ensembl:ENSP00000441158	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:clh2_human(display_long)|uniprotkb:CLTCL1(gene name)|psi-mi:CLTCL1(display_short)|uniprotkb:CLH22(gene name synonym)|uniprotkb:CLTCL(gene name synonym)|uniprotkb:CLTD(gene name synonym)|uniprotkb:Clathrin heavy chain on chromosome 22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001826.3|refseq:NP_009029.3|ensembl:ENSG00000070371(gene)|ensembl:ENST00000427926(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030135"(coated vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071439"(clathrin complex)|go:"GO:0097443"(sorting endosome)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-3928665|reactome:R-HSA-8856825|reactome:R-HSA-8856828	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:s+bmcNpUy0+PyN1d5eXCAvHBqus9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P46063	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-2823728|uniprotkb:A8K6G2|ensembl:ENSP00000395449|ensembl:ENSP00000416739	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:recq1_human(display_long)|uniprotkb:RECQL(gene name)|psi-mi:RECQL(display_short)|uniprotkb:RECQ1(gene name synonym)|uniprotkb:RECQL1(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 1(gene name synonym)|uniprotkb:DNA-dependent ATPase Q1(gene name synonym)|uniprotkb:RecQ protein-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_002898.2|refseq:NP_116559.1|ensembl:ENSG00000004700(gene)|ensembl:ENST00000421138(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|mint:P46063|rcsb pdb:2V1X|rcsb pdb:2WWY|rcsb pdb:4U7D|rcsb pdb:6JTZ|ensembl:ENST00000444129(transcript)|refseq:XP_005253518.1|refseq:XP_005253519.1|refseq:XP_005253520.1|refseq:XP_005253521.1|dip:DIP-29216N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:zJXPLIWtbjvhAhWH0HN+qdkCCOg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P42166	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P41091	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001406.1|ensembl:ENSG00000130741(gene)|ensembl:ENST00000253039(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR044127|interpro:IPR044128|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P33992	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P27448	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P27348	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P26232	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-3953920|uniprotkb:B3KXE5|uniprotkb:B7Z2W7|uniprotkb:B7Z352|uniprotkb:B7Z898|uniprotkb:Q4ZFW1|uniprotkb:Q53R26|uniprotkb:Q53R33|uniprotkb:Q53T67|uniprotkb:Q53T71|uniprotkb:Q53TM8|uniprotkb:Q7Z3L1|uniprotkb:Q7Z3Y0|ensembl:ENSP00000384638	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ctna2_human(display_long)|uniprotkb:CTNNA2(gene name)|psi-mi:CTNNA2(display_short)|uniprotkb:CAPR(gene name synonym)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001269526.1|refseq:NP_001269527.1|refseq:NP_001269528.1|refseq:NP_001269529.1|refseq:XP_011530857.1|refseq:XP_011530858.1|refseq:NP_001158355.1|refseq:NP_004380.2|ensembl:ENSG00000066032(gene)|ensembl:ENST00000402739(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|rcsb pdb:6DUW|reactome:R-HSA-525793|go:"GO:0005829"(cytosol)|refseq:NP_001307739.1|refseq:XP_016858892.1|dip:DIP-60979N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:Ms14mzGAhm356B/enTGIoPN5L5s9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P26196	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P23246	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P18887	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P17252	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1383528|uniprotkb:Q96RE4|uniprotkb:Q15137|uniprotkb:Q32M72|uniprotkb:B5BU22|ensembl:ENSP00000408695	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:kpca_human(display_long)|uniprotkb:PRKCA(gene name)|psi-mi:PRKCA(display_short)|uniprotkb:PKCA(gene name synonym)|uniprotkb:PRKACA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_002728.1|dip:DIP-531N|ensembl:ENSG00000154229(gene)|ensembl:ENST00000413366(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002159"(desmosome assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035408"(histone H3-T6 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000707"(positive regulation of dense core granule biogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034663|interpro:IPR035892|mint:P17252|rcsb pdb:2ELI|rcsb pdb:3IW4|rcsb pdb:4DNL|rcsb pdb:4RA4|reactome:R-HSA-111933|reactome:R-HSA-114516|reactome:R-HSA-1250196|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2179392|reactome:R-HSA-2514859|reactome:R-HSA-3000170|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416993|reactome:R-HSA-418597|reactome:R-HSA-4419969|reactome:R-HSA-450520|reactome:R-HSA-5099900|go:"GO:0043488"(regulation of mRNA stability)|reactome:R-HSA-5668599|reactome:R-HSA-76005|reactome:R-HSA-8853659|reactome:R-HSA-9010642|reactome:R-HSA-5218921	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:VW6o9vP7DTAQT2W9hEmyCLjoEX09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P16070	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-490245|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370|ensembl:ENSP00000398632	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|ensembl:ENSG00000026508(gene)|ensembl:ENST00000428726(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051216"(cartilage development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|dip:DIP-1121N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P13995	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1058895|ensembl:ENSP00000377617|uniprotkb:Q7Z650|uniprotkb:Q53G90|uniprotkb:Q53GV5|uniprotkb:Q53S36	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:mtdc_human(display_long)|uniprotkb:MTHFD2(gene name)|psi-mi:MTHFD2(display_short)|uniprotkb:NMDMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000065911(gene)|ensembl:ENST00000394053(transcript)|go:"GO:0000287"(magnesium ion binding)|rcsb pdb:1ZN4|rcsb pdb:5TC4|rcsb pdb:6JIB|rcsb pdb:6JID|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR036291|rcsb pdb:6KG2|refseq:XP_006711987.1|refseq:NP_006627.2|reactome:R-HSA-196757	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:dzNq2WEcKJ3DptZUIAnyKCITCsk9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P09496	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:P05198	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O94973	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENST00000448903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O94973|reactome:R-HSA-167590|ensembl:ENSG00000183020(gene)|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O75694	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O75607	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:lryH+qFG3/zmXWyn25dmU44prpk9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O75083	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O60869	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O60506	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O43324	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O14976	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-714707|uniprotkb:Q9BVY6|uniprotkb:Q5U4P5|intact:EBI-28970318|ensembl:ENSP00000314499	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:gak_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSP00000314499|ensembl:ENST00000511163|ensembl:ENSP00000421361|refseq:NP_005246.2|refseq:NP_001305063.1|ensembl:ENSG00000178950(gene)|ensembl:ENST00000314167(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR036869|rcsb pdb:4C57|rcsb pdb:4C58|rcsb pdb:4C59|rcsb pdb:4O38|rcsb pdb:4Y8D|rcsb pdb:5Y7Z|rcsb pdb:5Y80|reactome:R-HSA-432722|reactome:R-HSA-8856828|go:"GO:0072318"(clathrin coat disassembly)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:+CTVzAL9y1B3+JIg6PHsj8QXIjE9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:O00291	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-473886|uniprotkb:O00328|uniprotkb:Q8TDL4|uniprotkb:Q2TB58|uniprotkb:V5LU97|uniprotkb:B4E3I7|uniprotkb:E7ES17|ensembl:ENSP00000336747	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:hip1_human(display_long)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short)|uniprotkb:Huntingtin-interacting protein I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0051015"(actin filament binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099637"(neurotransmitter receptor transport)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR030554|interpro:IPR032422|interpro:IPR035964|mint:O00291|rcsb pdb:2NO2|rcsb pdb:2QA7|rcsb pdb:3I00|reactome:R-HSA-8856828|refseq:NP_005329.3|refseq:NP_001230127.1|refseq:XP_005250361.1|refseq:XP_011514418.1|ensembl:ENSG00000127946(gene)|ensembl:ENST00000336926(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050821"(protein stabilization)|dip:DIP-17041N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:tv7gJyUeUPo98+42G8L980EnE/c9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:H3BND3	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21261036|ensembl:ENSP00000454790	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:h3bnd3_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000167005(gene)|ensembl:ENST00000566340(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016787"(hydrolase activity)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:TI5fDynBieuRJX3FZfqTTPCUwI09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:H0YAE2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21261025|ensembl:ENSP00000426842	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:h0yae2_human(display_long)|uniprotkb:FCHO2(gene name)|psi-mi:FCHO2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000157107(gene)|ensembl:ENST00000507345(transcript)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR027267|interpro:IPR030122|interpro:IPR031160	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:bGAatum7vgxNMvqngax4J4Lwofc9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:H0Y8G5	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21261013|ensembl:ENSP00000420926	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:h0y8g5_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000138668(gene)|ensembl:ENST00000509263(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:KaVfwlyhtt8RWFYcIxAT1s7Z3ag9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:F8VRD2	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21261005|ensembl:ENSP00000448697	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:f8vrd2_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000161800(gene)|ensembl:ENST00000552310(transcript)|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:+TaqRZpsPlIIziSlAIvmPtmyqCY9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:E9PMS6	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-11030088|ensembl:ENSP00000431129	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:e9pms6_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000136153(gene)|ensembl:ENST00000526202(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:hXDMRMpvBWrOaT+cEyvVsA86jVs9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:E9PAV3	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-11035679|intact:EBI-28974260|ensembl:ENSP00000403817	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:nacam_human(display_long)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSP00000403817|ensembl:ENST00000550952|ensembl:ENSP00000448035|refseq:XP_011536691.1|ensembl:ENSG00000196531(gene)|ensembl:ENST00000454682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:tDgXpWjnQ69ngTZSPzERd50DEk49606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:E7EUA0	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21260998|ensembl:ENSP00000411902	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:e7eua0_human(display_long)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000162614(gene)|ensembl:ENST00000440324(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|interpro:IPR043204	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:SlTPTP3OarDZU+8vTbyeo9nHhLU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:C9JYS8	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21260985|ensembl:ENSP00000413350	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:c9jys8_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000147140(gene)|ensembl:ENST00000413858(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:GtpR/hEDDTDI4cgs6RpvmIAC4oU9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:B0QY01	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21260971|ensembl:ENSP00000393714	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:b0qy01_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000456128(transcript)|go:"GO:0015031"(protein transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:jdtzmZffSWVRwOcqA9DBmfKdUHI9606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:A8K3Q9	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-10174314	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:a8k3q9_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	interpro:IPR041985|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:j616/CNgbYEAH+NvWkfjXpZWqo89606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y586	uniprotkb:A6NLN1	intact:EBI-6659161|ensembl:ENSP00000324701|uniprotkb:B3KP37|uniprotkb:Q9HBA7	intact:EBI-21260952|ensembl:ENSP00000342332	psi-mi:mb212_human(display_long)|uniprotkb:MAB21L2(gene name)|psi-mi:MAB21L2(display_short)	psi-mi:a6nln1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:hCG_20560(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261050|imex:IM-26691-165	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000181541(gene)|ensembl:ENST00000317605(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0043010"(camera-type eye development)|interpro:IPR000772(Ricin B lectin)|interpro:IPR020950|interpro:IPR024810|refseq:NP_006430.1	interpro:IPR021790|interpro:IPR034798|interpro:IPR035001|ensembl:ENSG00000011304(gene)|ensembl:ENST00000350092(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035000|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:zZslnzjkfxOSAaUuj/hEcvXn98M9606	rogid:u1acIbk3sUtk1Xz36eSvfwApxx09606	rigid:DRPNnlSwcLpzPArIC3UyMNBB8Xk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9UQ80	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9Y5L4	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9Y5J9	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9Y3Z3	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9ULX3	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-373285|uniprotkb:Q7L6B7|uniprotkb:Q7M4M4|uniprotkb:Q7Z4B5|uniprotkb:Q9NWB0|ensembl:ENSP00000268802	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:nob1_human(display_long)|uniprotkb:NOB1(gene name)|psi-mi:NOB1(display_short)|uniprotkb:Protein ART-4(gene name synonym)|uniprotkb:Phosphorylation regulatory protein HP-10(gene name synonym)|uniprotkb:ART4(gene name synonym)|uniprotkb:NOB1P(gene name synonym)|uniprotkb:PSMD8BP1(gene name synonym)|uniprotkb:MSTP158(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_054781.1|ensembl:ENSG00000141101(gene)|ensembl:ENST00000268802(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0046872"(metal ion binding)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR014881("Nin one binding (NOB1) Zn-ribbon like")|interpro:IPR017117(D-site 20S pre-rRNA nuclease)|interpro:IPR033411|interpro:IPR033461|interpro:IPR036283|interpro:IPR039907|mint:Q9ULX3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:/Xk2PcxpyxjcG5gvs2VtLK6QmvA9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9UII4	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|intact:EBI-28975860|ensembl:ENSP00000264350	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSP00000264350|refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646(gene)|ensembl:ENST00000264350(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|mint:Q9UII4|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9H446	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-748952|uniprotkb:Q9Y313|uniprotkb:Q9Y6B3|uniprotkb:A8K3W2|uniprotkb:A8MT24|ensembl:ENSP00000420357	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:rwdd1_human(display_long)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:RWDD1(gene name)|psi-mi:RWDD1(display_short)|uniprotkb:CGI-24(orf name)|uniprotkb:PTD013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_057036.2|refseq:NP_001007465.1|refseq:NP_057188.2|ensembl:ENST00000466444(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005844"(polysome)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|ensembl:ENSG00000111832(gene)|interpro:IPR040213|rcsb pdb:2EBM|interpro:IPR032378|dip:DIP-34520N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:OvfJFwoLwchgGBS56iOdvVs0TDg9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9H3U1	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1048763|uniprotkb:Q7L3Y6|uniprotkb:Q9H3U8|uniprotkb:Q9NSE8|uniprotkb:Q9NSE9|uniprotkb:A8K6F7|ensembl:ENSP00000407487	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:un45a_human(display_long)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:SMAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001034764.1|refseq:NP_061141.2|refseq:XP_011520081.1|ensembl:ENSG00000140553(gene)|ensembl:ENST00000418476(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660|rcsb pdb:2DBA|refseq:NP_001310548.1|refseq:NP_001310550.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:P/N+VqGUtK2vWzHyKq6UzC4xxdo9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q96SB4	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-539478|uniprotkb:Q12890|uniprotkb:Q5R364|uniprotkb:Q5R365|uniprotkb:Q8IY12|uniprotkb:B4DS61|ensembl:ENSP00000362931	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:srpk1_human(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_003128.3|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q96SB4|rcsb pdb:1WAK|rcsb pdb:1WBP|rcsb pdb:3BEG|rcsb pdb:4WUA|rcsb pdb:5MXX|rcsb pdb:5MY8|rcsb pdb:5NNG|rcsb pdb:5XV7|rcsb pdb:6FAD|rcsb pdb:7DD1|dip:DIP-33888N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q96CT7	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-5461329|ensembl:ENSP00000408730|ensembl:ENSP00000471455	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:cc124_human(display_long)|uniprotkb:CCDC124(gene name)|psi-mi:CCDC124(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001129675.1|refseq:NP_612451.1|ensembl:ENSG00000007080(gene)|ensembl:ENST00000445755(transcript)|ensembl:ENST00000597436(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|interpro:IPR010422(Protein of unknown function DUF1014)|mint:Q96CT7|rcsb pdb:6Z6L|rcsb pdb:6ZM7|rcsb pdb:6ZME	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:w3LqsScVHWABZgIwYZXS6Ly9CiM9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q92974	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-302405|intact:EBI-1045693|uniprotkb:O75142|uniprotkb:Q15079|uniprotkb:Q5VY92|uniprotkb:Q8TDA3|uniprotkb:Q8WUG4|uniprotkb:Q9H023|ensembl:ENSP00000354837|uniprotkb:D3DVA6	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:arhg2_human(display_long)|uniprotkb:ARHGEF2(gene name)|psi-mi:ARHGEF2(display_short)|uniprotkb:KIAA0651(gene name synonym)|uniprotkb:LFP40(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Microtubule-regulated Rho-GEF(gene name synonym)|uniprotkb:Proliferating cell nucleolar antigen p40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001155855.1|refseq:NP_001155856.1|refseq:NP_004714.2|ensembl:ENSG00000116584(gene)|ensembl:ENST00000361247(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q92974|rcsb pdb:5EFX|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:GljUl7uzMi3HaFQsMybfT6KrW089606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q86UE4	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1046588|ensembl:ENSP00000338235|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|uniprotkb:Q05DH2|uniprotkb:Q52QU9	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSG00000147649(gene)|ensembl:ENST00000336273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q7Z2T5	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1237316|uniprotkb:Q5TEN0|uniprotkb:Q6ZMX0|uniprotkb:Q8IWH5|uniprotkb:Q8NC68|uniprotkb:Q9BZQ1|ensembl:ENSP00000356476	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:trm1l_human(display_long)|uniprotkb:TRMT1L(gene name)|psi-mi:TRMT1L(display_short)|uniprotkb:C1orf25(gene name synonym)|uniprotkb:MSTP070(orf name)|uniprotkb:TRM1L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001189352.1|refseq:NP_112196.3|ensembl:ENSG00000121486(gene)|ensembl:ENST00000367506(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002940"(tRNA N2-guanine methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0007610"(behavior)|go:"GO:0046872"(metal ion binding)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029063|interpro:IPR042296	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:dctCUlcYZCnaX72mW3b0n9JM5w89606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q71UM5	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q58FF8	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-2961708	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q16543	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q15477	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-373226|uniprotkb:O15005|uniprotkb:Q12902|uniprotkb:Q15476|intact:EBI-1058949|uniprotkb:Q5ST66|ensembl:ENSP00000364543|ensembl:ENSP00000372827|ensembl:ENSP00000394400|ensembl:ENSP00000399530|ensembl:ENSP00000400626|ensembl:ENSP00000412310	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:skiv2_human(display_long)|uniprotkb:SKIV2L(gene name)|psi-mi:SKIV2L(display_short)|uniprotkb:DDX13(gene name synonym)|uniprotkb:SKI2W(gene name synonym)|uniprotkb:SKIV2(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:Helicase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_008860.4|ensembl:ENSG00000204351(gene)|ensembl:ENSG00000206353(gene)|ensembl:ENSG00000223493(gene)|ensembl:ENSG00000225737(gene)|ensembl:ENSG00000228896(gene)|ensembl:ENSG00000232616(gene)|ensembl:ENST00000375394(transcript)|ensembl:ENST00000383336(transcript)|ensembl:ENST00000412823(transcript)|ensembl:ENST00000421789(transcript)|ensembl:ENST00000429465(transcript)|ensembl:ENST00000448219(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|interpro:IPR040801|mint:Q15477|reactome:R-HSA-390471|reactome:R-HSA-429958	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:+42a3/XPqsM8hc3qP2M9n/pZ+bY9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q14974	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q13576	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q13243	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q13114	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-357631|uniprotkb:Q12990|uniprotkb:Q13076|uniprotkb:Q13947|uniprotkb:Q6AZX1|uniprotkb:Q9UNL1|ensembl:ENSP00000376500|ensembl:ENSP00000454207|uniprotkb:B7Z8C4	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:traf3_human(display_long)|uniprotkb:TRAF3(gene name)|psi-mi:TRAF3(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:CRAF1(gene name synonym)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:CD40-binding protein(gene name synonym)|uniprotkb:LMP1-associated protein 1(gene name synonym)|uniprotkb:CAP-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSG00000131323(gene)|ensembl:ENST00000392745(transcript)|ensembl:ENST00000560371(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|refseq:NP_001186356.1|refseq:NP_003291.2|refseq:NP_663777.1|refseq:NP_663778.1|go:"GO:0007165"(signal transduction)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q13114|go:"GO:0042981"(regulation of apoptotic process)|rcsb pdb:1FLK|rcsb pdb:1FLL|rcsb pdb:1L0A|rcsb pdb:1RF3|rcsb pdb:1ZMS|rcsb pdb:2ECY|rcsb pdb:2GKW|rcsb pdb:1KZZ|refseq:XP_011535420.1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|reactome:R-HSA-5689896|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-5602571|refseq:XP_016877106.1|refseq:XP_016877107.1|dip:DIP-6222N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:9Tjx/USypDBBrPVyFOsLzM/bwzA9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q12904	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1045802|uniprotkb:Q6FG28|uniprotkb:Q96CQ9|uniprotkb:B4E1S7|uniprotkb:B3KTR2|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:aimp1_human(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001135887.1|refseq:NP_001135888.1|refseq:NP_004748.2|ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q12904|rcsb pdb:1E7Z|rcsb pdb:1EUJ|rcsb pdb:1FL0|rcsb pdb:4R3Z|reactome:R-HSA-2408522|reactome:R-HSA-379716|refseq:XP_016864324.1|refseq:XP_016864325.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q01201	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-357837|uniprotkb:Q6GTX7|uniprotkb:Q9UEI7|intact:EBI-28977965|ensembl:ENSP00000221452|ensembl:ENSP00000485826	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:relb_human(display_long)|uniprotkb:RELB(gene name)|psi-mi:RELB(display_short)|uniprotkb:I-Rel(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_006500.2|ensembl:ENSP00000221452|ensembl:ENSP00000485826|dip:DIP-27531N|ensembl:ENSG00000104856(gene)|ensembl:ENST00000221452(transcript)|ensembl:ENST00000625761(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|reactome:R-HSA-5607761|reactome:R-HSA-5621575|reactome:R-HSA-5676590	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:Z86381sTm70DDTlOVNTvJOHiWug9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q00653	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:P51116	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:P27708	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:P20073	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|intact:EBI-28973842|ensembl:ENSP00000362010	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSP00000362010|ensembl:ENST00000372921|ensembl:ENSP00000362012|refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279(gene)|ensembl:ENST00000372919(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061025"(membrane fusion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:P07900	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:P05386	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O60220	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O43324	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O15160	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O15111	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O14920	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-81266|uniprotkb:O75327|uniprotkb:B4E0U4|uniprotkb:B4DZ30|ensembl:ENSP00000430684	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:ikkb_human(display_long)|uniprotkb:IKBKB(gene name)|psi-mi:IKBKB(display_short)|uniprotkb:IKKB(gene name synonym)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001177649.1|refseq:NP_001547.1|interpro:IPR000626(Ubiquitin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022007|interpro:IPR029071|interpro:IPR041185|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|mint:O14920|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:4E3C|rcsb pdb:4KIK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209543|reactome:R-HSA-209560|ensembl:ENSG00000104365(gene)|ensembl:ENST00000520810(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|reactome:R-HSA-2871837|go:"GO:0019901"(protein kinase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903140"(regulation of establishment of endothelial barrier)|refseq:NP_001229707.1|dip:DIP-27527N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:Za/bWjmPFaKOGVvQ00rtBfikvhI9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O14744	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:O00410	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:C9JN51	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-21261365|ensembl:ENSP00000394934	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:c9jn51_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENST00000440286(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR021063|ensembl:ENSG00000269335(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:cDVzexiP9eRaQUf0LL5qTSlKUmQ9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:C9JMM3	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-21261353|ensembl:ENSP00000408668	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:c9jmm3_human(display_long)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSG00000180228(gene)|ensembl:ENST00000457633(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033363|interpro:IPR044465	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:tmnbVH3X8IFg/IFtaa78+qcAFQE9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:C9J4M6	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:C9J2V2	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-21261344|ensembl:ENSP00000398579	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:c9j2v2_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261374|imex:IM-26691-71	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSG00000269335(gene)|ensembl:ENST00000413620(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR021063	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/04/12	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:9gO81VKuTa8h6Ek2rJwlsW7Zue49606	rigid:5OUt4SzhfkyZE/JfozRvesKDmRU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N884	uniprotkb:P53004	intact:EBI-11040161|uniprotkb:Q5SWL0|uniprotkb:Q5SWL1|uniprotkb:Q14CV6|uniprotkb:Q32NC9|uniprotkb:Q96E45|uniprotkb:L0L2J9|ensembl:ENSP00000359339	intact:EBI-7410441|intact:MINT-1212210|uniprotkb:Q96QL4|uniprotkb:A8K747|uniprotkb:Q9BRW8|uniprotkb:Q86UX0|uniprotkb:O95019|ensembl:ENSP00000265523|ensembl:ENSP00000385757	psi-mi:cgas_human(display_long)|uniprotkb:CGAS(gene name)|psi-mi:CGAS(display_short)|uniprotkb:2'3'-cGAMP synthase(gene name synonym)|uniprotkb:C6orf150(gene name synonym)|uniprotkb:MB21D1(gene name synonym)|uniprotkb:Mab-21 domain-containing protein 1(gene name synonym)	psi-mi:biea_human(display_long)|uniprotkb:BLVRA(gene name)|psi-mi:BLVRA(display_short)|uniprotkb:BLVR(gene name synonym)|uniprotkb:BVR(gene name synonym)|uniprotkb:Biliverdin-IX alpha-reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261500|imex:IM-26691-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612450.2|ensembl:ENSG00000164430(gene)|ensembl:ENST00000370315(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035861"(site of double-strand break)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0061501"(2',3'-cyclic GMP-AMP synthase activity)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR024810|rcsb pdb:4KM5|rcsb pdb:4LEV|rcsb pdb:4LEW|rcsb pdb:4MKP|rcsb pdb:4O67|rcsb pdb:4O68|rcsb pdb:4O69|rcsb pdb:5V8O|rcsb pdb:5VDO|rcsb pdb:5VDP|rcsb pdb:5VDQ|rcsb pdb:5VDR|rcsb pdb:5VDS|rcsb pdb:5VDT|rcsb pdb:5VDU|rcsb pdb:5VDV|rcsb pdb:5VDW|rcsb pdb:6CT9|rcsb pdb:6CTA|rcsb pdb:6EDB|rcsb pdb:6EDC|rcsb pdb:6LRC|rcsb pdb:6LRE|rcsb pdb:6LRI|rcsb pdb:6LRJ|rcsb pdb:6LRK|rcsb pdb:6LRL|rcsb pdb:6MJU|rcsb pdb:6MJW|rcsb pdb:6MJX|rcsb pdb:6NAO|rcsb pdb:6NFG|rcsb pdb:6NFO|rcsb pdb:6O47|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|reactome:R-HSA-1834941	refseq:XP_011513776.1|refseq:NP_001240752.1|refseq:NP_000703.2|refseq:XP_016868009.1|ensembl:ENSG00000106605(gene)|ensembl:ENST00000265523(transcript)|ensembl:ENST00000402924(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004074"("biliverdin reductase (NAD(P)+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042167"(heme catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106276"(biliberdin reductase NAD+ activity)|go:"GO:0106277"("biliverdin reductase (NADP+) activity")|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR015249(Biliverdin reductase, catalytic)|interpro:IPR017094(Biliverdin reductase A)|interpro:IPR036291|rcsb pdb:2H63|reactome:R-HSA-189483|reactome:R-HSA-9707564|dip:DIP-42180N	-	-	comment:mint|function:Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:jHb5dp380QcFfJNq8HAAmrZhjZQ9606	rogid:gcpdPe6YxaYS3dRJ3JRAeEpJbtk9606	rigid:ZjL0/ZijEK6s+fbLn0P9BdPJi70	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N884	uniprotkb:Q92598	intact:EBI-11040161|uniprotkb:Q5SWL0|uniprotkb:Q5SWL1|uniprotkb:Q14CV6|uniprotkb:Q32NC9|uniprotkb:Q96E45|uniprotkb:L0L2J9|ensembl:ENSP00000359339	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:cgas_human(display_long)|uniprotkb:CGAS(gene name)|psi-mi:CGAS(display_short)|uniprotkb:2'3'-cGAMP synthase(gene name synonym)|uniprotkb:C6orf150(gene name synonym)|uniprotkb:MB21D1(gene name synonym)|uniprotkb:Mab-21 domain-containing protein 1(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261500|imex:IM-26691-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612450.2|ensembl:ENSG00000164430(gene)|ensembl:ENST00000370315(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035861"(site of double-strand break)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0061501"(2',3'-cyclic GMP-AMP synthase activity)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR024810|rcsb pdb:4KM5|rcsb pdb:4LEV|rcsb pdb:4LEW|rcsb pdb:4MKP|rcsb pdb:4O67|rcsb pdb:4O68|rcsb pdb:4O69|rcsb pdb:5V8O|rcsb pdb:5VDO|rcsb pdb:5VDP|rcsb pdb:5VDQ|rcsb pdb:5VDR|rcsb pdb:5VDS|rcsb pdb:5VDT|rcsb pdb:5VDU|rcsb pdb:5VDV|rcsb pdb:5VDW|rcsb pdb:6CT9|rcsb pdb:6CTA|rcsb pdb:6EDB|rcsb pdb:6EDC|rcsb pdb:6LRC|rcsb pdb:6LRE|rcsb pdb:6LRI|rcsb pdb:6LRJ|rcsb pdb:6LRK|rcsb pdb:6LRL|rcsb pdb:6MJU|rcsb pdb:6MJW|rcsb pdb:6MJX|rcsb pdb:6NAO|rcsb pdb:6NFG|rcsb pdb:6NFO|rcsb pdb:6O47|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|reactome:R-HSA-1834941	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:jHb5dp380QcFfJNq8HAAmrZhjZQ9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:ZjL0/ZijEK6s+fbLn0P9BdPJi70	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N884	uniprotkb:P34932	intact:EBI-11040161|uniprotkb:Q5SWL0|uniprotkb:Q5SWL1|uniprotkb:Q14CV6|uniprotkb:Q32NC9|uniprotkb:Q96E45|uniprotkb:L0L2J9|ensembl:ENSP00000359339	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:cgas_human(display_long)|uniprotkb:CGAS(gene name)|psi-mi:CGAS(display_short)|uniprotkb:2'3'-cGAMP synthase(gene name synonym)|uniprotkb:C6orf150(gene name synonym)|uniprotkb:MB21D1(gene name synonym)|uniprotkb:Mab-21 domain-containing protein 1(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261500|imex:IM-26691-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612450.2|ensembl:ENSG00000164430(gene)|ensembl:ENST00000370315(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035861"(site of double-strand break)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0061501"(2',3'-cyclic GMP-AMP synthase activity)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR024810|rcsb pdb:4KM5|rcsb pdb:4LEV|rcsb pdb:4LEW|rcsb pdb:4MKP|rcsb pdb:4O67|rcsb pdb:4O68|rcsb pdb:4O69|rcsb pdb:5V8O|rcsb pdb:5VDO|rcsb pdb:5VDP|rcsb pdb:5VDQ|rcsb pdb:5VDR|rcsb pdb:5VDS|rcsb pdb:5VDT|rcsb pdb:5VDU|rcsb pdb:5VDV|rcsb pdb:5VDW|rcsb pdb:6CT9|rcsb pdb:6CTA|rcsb pdb:6EDB|rcsb pdb:6EDC|rcsb pdb:6LRC|rcsb pdb:6LRE|rcsb pdb:6LRI|rcsb pdb:6LRJ|rcsb pdb:6LRK|rcsb pdb:6LRL|rcsb pdb:6MJU|rcsb pdb:6MJW|rcsb pdb:6MJX|rcsb pdb:6NAO|rcsb pdb:6NFG|rcsb pdb:6NFO|rcsb pdb:6O47|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|reactome:R-HSA-1834941	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:jHb5dp380QcFfJNq8HAAmrZhjZQ9606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	rigid:ZjL0/ZijEK6s+fbLn0P9BdPJi70	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N884	uniprotkb:O95757	intact:EBI-11040161|uniprotkb:Q5SWL0|uniprotkb:Q5SWL1|uniprotkb:Q14CV6|uniprotkb:Q32NC9|uniprotkb:Q96E45|uniprotkb:L0L2J9|ensembl:ENSP00000359339	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:cgas_human(display_long)|uniprotkb:CGAS(gene name)|psi-mi:CGAS(display_short)|uniprotkb:2'3'-cGAMP synthase(gene name synonym)|uniprotkb:C6orf150(gene name synonym)|uniprotkb:MB21D1(gene name synonym)|uniprotkb:Mab-21 domain-containing protein 1(gene name synonym)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261500|imex:IM-26691-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612450.2|ensembl:ENSG00000164430(gene)|ensembl:ENST00000370315(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035861"(site of double-strand break)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051607"(defense response to virus)|go:"GO:0061501"(2',3'-cyclic GMP-AMP synthase activity)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR024810|rcsb pdb:4KM5|rcsb pdb:4LEV|rcsb pdb:4LEW|rcsb pdb:4MKP|rcsb pdb:4O67|rcsb pdb:4O68|rcsb pdb:4O69|rcsb pdb:5V8O|rcsb pdb:5VDO|rcsb pdb:5VDP|rcsb pdb:5VDQ|rcsb pdb:5VDR|rcsb pdb:5VDS|rcsb pdb:5VDT|rcsb pdb:5VDU|rcsb pdb:5VDV|rcsb pdb:5VDW|rcsb pdb:6CT9|rcsb pdb:6CTA|rcsb pdb:6EDB|rcsb pdb:6EDC|rcsb pdb:6LRC|rcsb pdb:6LRE|rcsb pdb:6LRI|rcsb pdb:6LRJ|rcsb pdb:6LRK|rcsb pdb:6LRL|rcsb pdb:6MJU|rcsb pdb:6MJW|rcsb pdb:6MJX|rcsb pdb:6NAO|rcsb pdb:6NFG|rcsb pdb:6NFO|rcsb pdb:6O47|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|reactome:R-HSA-1834941	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:jHb5dp380QcFfJNq8HAAmrZhjZQ9606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	rigid:ZjL0/ZijEK6s+fbLn0P9BdPJi70	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:Q9NSY1	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-1383367|uniprotkb:O94791|uniprotkb:Q8IYF2|uniprotkb:Q8N2G7|uniprotkb:Q8NHG9|uniprotkb:Q9NTG8|uniprotkb:Q4W5H2|intact:EBI-28972938|ensembl:ENSP00000424668	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:bmp2k_human(display_long)|uniprotkb:BMP2K(gene name)|psi-mi:BMP2K(display_short)|uniprotkb:BIKE(gene name synonym)|uniprotkb:HRIHFB2017(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	ensembl:ENSP00000424668|ensembl:ENST00000502871|ensembl:ENSP00000421768|refseq:NP_060063.2|refseq:NP_942595.1|ensembl:ENSG00000138756(gene)|ensembl:ENST00000502613(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026105|interpro:IPR028182|rcsb pdb:4W9W|rcsb pdb:4W9X|rcsb pdb:5I3O|rcsb pdb:5I3R|rcsb pdb:5IKW|go:"GO:0019208"(phosphatase regulator activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:ckhpP0erhSRURf04YvQFCsYZ8rY9606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:Q969Q0	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:+jT5oFy79StEavkvHz6j/36g/qg9606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:Q8NC51	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:Q12965	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:P62861	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-358093|uniprotkb:Q05472|uniprotkb:Q95261|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:rs30_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short)|uniprotkb:Small ribosomal subunit protein eS30(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR006846(Ribosomal protein S30)|mint:P62861|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:mfW+tko85h9ZOK7wNXUsYiYY3Hc9606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:P61513	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:0kwO2cVd99FGF2+5FyWo94C83049606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:P24844	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-716193|uniprotkb:Q9BQL9|uniprotkb:Q9BUF9|uniprotkb:Q9H136|uniprotkb:E1P5T6|ensembl:ENSP00000279022	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:myl9_human(display_long)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC1(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2C(gene name synonym)|uniprotkb:20 kDa myosin light chain(gene name synonym)|uniprotkb:MYL9(gene name)|psi-mi:MYL9(display_short)|uniprotkb:MRLC1(gene name synonym)|uniprotkb:MYRL2(gene name synonym)|uniprotkb:MLC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	refseq:NP_006088.2|refseq:NP_852667.1|ensembl:ENSG00000101335(gene)|ensembl:ENST00000279022(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0070527"(platelet aggregation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P24844|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-8936459|dip:DIP-60525N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:FeJb0ac0n3hkVmRDnxeGSlL2/A89606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:P09496	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H7Q8	uniprotkb:A8K3Q9	intact:EBI-21261518|ensembl:ENSP00000442345|ensembl:ENSP00000477804	intact:EBI-10174314	psi-mi:f5h7q8_human(display_long)|uniprotkb:MICB(gene name)|psi-mi:MICB(display_short)	psi-mi:a8k3q9_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261537|imex:IM-26691-151	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204516(gene)|ensembl:ENSG00000231179(gene)|ensembl:ENST00000538442(transcript)|ensembl:ENST00000619506(transcript)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|refseq:NP_001276089.1	interpro:IPR041985|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:6ZxcBQ2dgSAcDfziS/dkzpvldpk9606	rogid:j616/CNgbYEAH+NvWkfjXpZWqo89606	rigid:1eWAhb0OXkr+PMyIR/cqujozxoo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H0YKC7	uniprotkb:Q96JZ2	intact:EBI-21261569|ensembl:ENSP00000452751	intact:EBI-3919324|intact:EBI-28973686|ensembl:ENSP00000482604|ensembl:ENSP00000483354|uniprotkb:B5ME72|uniprotkb:Q6ZNG7	psi-mi:h0ykc7_human(display_long)|uniprotkb:MKX(gene name)|psi-mi:MKX(display_short)	psi-mi:hsh2d_human(display_long)|uniprotkb:HSH2D(gene name)|psi-mi:HSH2D(display_short)|uniprotkb:ALX(gene name synonym)|uniprotkb:Adaptor in lymphocytes of unknown function X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261596|imex:IM-26691-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150051(gene)|ensembl:ENST00000460919(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970	ensembl:ENSP00000483354|ensembl:ENSP00000482604|ensembl:ENSG00000196684(gene)|ensembl:ENST00000613986(transcript)|ensembl:ENST00000616645(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007165"(signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR035047|interpro:IPR036860|rcsb pdb:2CS0|go:"GO:0005737"(cytoplasm)|refseq:NP_116244.1|refseq:NP_001278203.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9/dJ6dAIJoMzvarFmariqj532Dc9606	rogid:Y01YjkfU/oOtbz2TdQcnm+lBWhs9606	rigid:ye1ENf6NVlH/yw7P9ZbprQtJ0wU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H0YKC7	uniprotkb:K7ERC4	intact:EBI-21261569|ensembl:ENSP00000452751	intact:EBI-21261583|ensembl:ENSP00000468198	psi-mi:h0ykc7_human(display_long)|uniprotkb:MKX(gene name)|psi-mi:MKX(display_short)	psi-mi:k7erc4_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261596|imex:IM-26691-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150051(gene)|ensembl:ENST00000460919(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970	ensembl:ENSG00000173786(gene)|ensembl:ENST00000587679(transcript)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0042470"(melanosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9/dJ6dAIJoMzvarFmariqj532Dc9606	rogid:/Vn3QzpFFSK47wQIhlyDko6Eu389606	rigid:ye1ENf6NVlH/yw7P9ZbprQtJ0wU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q9Y281	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q96I24	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q5BKZ1	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-2560158|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|ensembl:ENSP00000340796|uniprotkb:A8MYX1|uniprotkb:B4E179	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	refseq:NP_892020.1|refseq:NP_892021.1|refseq:XP_011539592.1|ensembl:ENSG00000162664(gene)|ensembl:ENST00000340281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q1KMD3	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-1059150|uniprotkb:Q8N3B3|ensembl:ENSP00000301785	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:hnrl2_human(display_long)|uniprotkb:HNRNPUL2(gene name)|psi-mi:HNRNPUL2(display_short)|uniprotkb:HNRPUL2(gene name synonym)|uniprotkb:Scaffold-attachment factor A2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	refseq:NP_001073027.1|ensembl:ENSG00000214753(gene)|ensembl:ENST00000301785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q1KMD3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:TOoq1VTfNNzysqSyPH9MHLbSKPA9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q13151	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:Q09161	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:P82663	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:O00425	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:B1AKQ8	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-6190833|ensembl:ENSP00000416651	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:b1akq8_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	ensembl:ENSG00000078369(gene)|ensembl:ENST00000437146(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR036322	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:BUB/7mf+WlDyk4rDXHXUrW9rKWE9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:B0QYC4	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-21261619|ensembl:ENSP00000416239	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:b0qyc4_human(display_long)|uniprotkb:CARD10(gene name)|psi-mi:CARD10(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	ensembl:ENSG00000100065(gene)|ensembl:ENST00000437756(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:yKIohe6lgLEkl+wSNDkMChBQZuE9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:A6NLN1	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-21260952|ensembl:ENSP00000342332	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:a6nln1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:hCG_20560(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	interpro:IPR021790|interpro:IPR034798|interpro:IPR035001|ensembl:ENSG00000011304(gene)|ensembl:ENST00000350092(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035000|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:u1acIbk3sUtk1Xz36eSvfwApxx09606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HCE1	uniprotkb:A0A0B4J210	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	intact:EBI-21261608|ensembl:ENSP00000428589	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:a0a0b4j210_human(display_long)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261626|imex:IM-26691-123	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rogid:JhmSJsGytpAfTKbzSVdqNiGzXBw9606	rigid:Zt4Rs7ikoo1nKLFUFi2+mhBm7TQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q9Y4W6	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q9Y241	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q9UI12	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q9UI10	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q9HAV4	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q99653	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q96JJ7	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q8TEM1	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q86Y56	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-719966|uniprotkb:Q69YL1|uniprotkb:Q96FI9|uniprotkb:Q9NX75|ensembl:ENSP00000297440	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:daaf5_human(display_long)|uniprotkb:DNAAF5(gene name)|psi-mi:DNAAF5(display_short)|uniprotkb:HEAT repeat-containing protein 2(gene name synonym)|uniprotkb:HEATR2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_060272.3|ensembl:ENSG00000164818(gene)|ensembl:ENST00000297440(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0005737"(cytoplasm)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|mint:Q86Y56	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:5AmIkT2NW1/GyC8udQmrI5hRAsU9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q86VP6	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q5VYK3	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-521451|uniprotkb:O15074|uniprotkb:Q8WU82|ensembl:ENSP00000339889	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:XP_005251907.1|ensembl:ENSG00000136813(gene)|ensembl:ENST00000338205(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043248"(proteasome assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q53GQ0	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q15645	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q14254	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-348613|ensembl:ENSP00000378368	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_004466.2|ensembl:ENSG00000132589(gene)|go:"GO:0008544"(epidermis development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|ensembl:ENST00000394908(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:Q02978	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:P78527	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:P55060	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:P51648	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:P51617	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:P45954	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-2511905|ensembl:ENSP00000357873|uniprotkb:Q96CX7|uniprotkb:B4DQ51|uniprotkb:Q5SQN6	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:acdsb_human(display_long)|uniprotkb:ACADSB(gene name)|psi-mi:ACADSB(display_short)|uniprotkb:2-methyl branched chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:2-methylbutyryl-coenzyme A dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENSG00000196177(gene)|ensembl:ENST00000358776(transcript)|go:"GO:0003853"(2-methylacyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016937"(short-branched-chain-acyl-CoA dehydrogenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102035"("isobutyryl-CoA:FAD oxidoreductase activity")|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|rcsb pdb:2JIF|reactome:R-HSA-70895|refseq:NP_001600.1|refseq:NP_001317103.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:phnlWtZGT21VyKrhWj9a3Wjfijw9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:O43592	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:O43175	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:O15120	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-3935937|uniprotkb:Q9BWR7|uniprotkb:O00516|uniprotkb:Q5VUD4|uniprotkb:Q9BSV7|uniprotkb:O15106|uniprotkb:Q5VUD3|intact:EBI-28988552|ensembl:ENSP00000360761|ensembl:ENSP00000438919	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:plcb_human(display_long)|uniprotkb:AGPAT2(gene name)|psi-mi:AGPAT2(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 2(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:NP_001012745.1|refseq:NP_006403.2|ensembl:ENST00000371694|ensembl:ENSP00000360759|ensembl:ENSP00000360761|ensembl:ENSP00000438919|ensembl:ENSG00000169692(gene)|ensembl:ENST00000371696(transcript)|ensembl:ENST00000538402(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:quJFJpDvkJbjDx+PiTqRDpLfqzg9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:O14980	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:M0QZX5	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-21261668|ensembl:ENSP00000470834	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:m0qzx5_human(display_long)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	ensembl:ENSG00000105135(gene)|ensembl:ENST00000598709(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR029035	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:hXycrRCQFMdvAFb4dmK4T7Z6NM89606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:E1NZA1	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-21258417	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96JQ5	uniprotkb:B7ZM73	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-21260321	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261679|imex:IM-26691-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	rigid:aY776BZmxCByd6nD/aJkQIfHeS4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20591	uniprotkb:Q68D27	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-21261767	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:q68d27_human(display_long)|uniprotkb:DKFZp686B20267(gene name)|psi-mi:DKFZp686B20267(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261783|imex:IM-26691-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|refseq:NP_001280202.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:THsbOklraRO84LO3t3QenHcGLRY9606	rigid:QnJ7qFtrSioy0J/zgiVnPlkt4no	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20591	uniprotkb:Q08380	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261783|imex:IM-26691-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:QnJ7qFtrSioy0J/zgiVnPlkt4no	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20591	uniprotkb:P63167	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261783|imex:IM-26691-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	rigid:QnJ7qFtrSioy0J/zgiVnPlkt4no	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20591	uniprotkb:P12532	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261783|imex:IM-26691-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606	rigid:QnJ7qFtrSioy0J/zgiVnPlkt4no	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P20591	uniprotkb:O75096	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-310873|uniprotkb:B2RN39|uniprotkb:Q4AC85|uniprotkb:Q5KTZ5|ensembl:ENSP00000367888	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:lrp4_human(display_long)|uniprotkb:LRP4(gene name)|psi-mi:LRP4(display_short)|uniprotkb:KIAA0816(gene name synonym)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains 7(gene name synonym)|uniprotkb:LRP10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261783|imex:IM-26691-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	refseq:NP_002325.2|ensembl:ENSG00000134569(gene)|ensembl:ENST00000378623(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001942"(hair follicle development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060173"(limb development)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:O75096|reactome:R-HSA-3000178	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:IbVlpu46vNtRqtZvYsySZ6go3kE9606	rigid:QnJ7qFtrSioy0J/zgiVnPlkt4no	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:H0YL12	uniprotkb:P43490	intact:EBI-21259817|ensembl:ENSP00000453017	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	psi-mi:h0yl12_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261804|imex:IM-26691-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005759"(mitochondrial matrix)|ensembl:ENSG00000140374(gene)|ensembl:ENST00000560345(transcript)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR029035|interpro:IPR033947	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Cw4dRHI2p2B3Ge4EJBFj2UT9b2Q9606	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rigid:6/O61fTMrQPAcU/XQzwUw9UZZr8	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O43264	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:A2RRP1	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_056993.2|dip:DIP-56726N|ensembl:ENSG00000151779(gene)|ensembl:ENST00000281513(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR029145|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9UNK0	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9UEU0	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-723716|ensembl:ENSP00000450731|uniprotkb:O43547|uniprotkb:Q96J28	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vti1b_human(display_long)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 1(gene name synonym)|uniprotkb:Vti1-rp1(gene name synonym)|uniprotkb:VTI1B(gene name)|psi-mi:VTI1B(display_short)|uniprotkb:VTI1(gene name synonym)|uniprotkb:VTI1L(gene name synonym)|uniprotkb:VTI1L1(gene name synonym)|uniprotkb:VTI2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_006361.1|ensembl:ENSG00000100568(gene)|ensembl:ENST00000554659(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR038407|rcsb pdb:2V8S|reactome:R-HSA-114608|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:jJgdeKpTRzoaVS5zj+cPGKj05OM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9P2W9	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|ensembl:ENSG00000168818(gene)|ensembl:ENST00000306200(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1902117"(positive regulation of organelle assembly)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|dip:DIP-37617N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9NZ43	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-742842|uniprotkb:Q8NCK1|uniprotkb:Q9BRT4|ensembl:ENSP00000263897	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:use1_human(display_long)|uniprotkb:USE1L(gene name synonym)|uniprotkb:USE1-like protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM26(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:USE1(gene name)|psi-mi:USE1(display_short)|uniprotkb:MDS032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_060937.1|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015031"(protein transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031201"(SNARE complex)|go:"GO:0032940"(secretion by cell)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR019150|reactome:R-HSA-6811434|ensembl:ENSG00000053501(gene)|ensembl:ENST00000263897(transcript)|go:"GO:0005484"(SNAP receptor activity)|refseq:XP_016882464.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:Q1yMpc/L7/G3M+SehF5ix99OkVM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9NYM9	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-3924542|uniprotkb:B3KMY0|ensembl:ENSP00000372210	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:bet1l_human(display_long)|uniprotkb:BET1L(gene name)|psi-mi:BET1L(display_short)|uniprotkb:GS15(gene name synonym)|uniprotkb:Golgi SNARE with a size of 15 kDa(gene name synonym)|uniprotkb:Vesicle transport protein GOS15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001092257.1|ensembl:ENSG00000177951(gene)|ensembl:ENST00000382762(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|reactome:R-HSA-6807878|reactome:R-HSA-6811438|go:"GO:0031201"(SNARE complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:y5Ckvg6zKZghOu2wYZAwjymtibw9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9NRW7	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-1782543|uniprotkb:Q15715|uniprotkb:Q9Y4Z6|uniprotkb:Q5T4P6|uniprotkb:F5H8K1|uniprotkb:Q53FR8|uniprotkb:D3DUZ9|ensembl:ENSP00000495563	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vps45_human(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:VPS45A(gene name synonym)|uniprotkb:VPS45B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	dip:DIP-46823N|refseq:NP_009190.2|refseq:NP_001266282.1|refseq:NP_001266283.1|ensembl:ENSG00000136631(gene)|ensembl:ENST00000644510(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-HSA-6811438|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:EO8eXkh8EW/0AN2p5OqHL4yvXV09606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q9H444	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q99747	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-3221833|uniprotkb:B4DFC9|ensembl:ENSP00000324628|uniprotkb:Q9BUV1	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:snag_human(display_long)|uniprotkb:NAPG(gene name)|psi-mi:NAPG(display_short)|uniprotkb:SNAPG(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000134265(gene)|ensembl:ENST00000322897(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0045202"(synapse)|go:"GO:0050821"(protein stabilization)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q99747|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:XP_011524058.1|refseq:NP_003817.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:QbHDxqDWn6/UYiMIOMiKfx5eCFg9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q96AJ9	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-3923262|uniprotkb:B4E137|uniprotkb:A2A307|ensembl:ENSP00000376792|uniprotkb:Q5W0D7	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vti1a_human(display_long)|uniprotkb:VTI1A(gene name)|psi-mi:VTI1A(display_short)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 2(gene name synonym)|uniprotkb:Vti1-rp2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_660207.2|ensembl:ENSG00000151532(gene)|ensembl:ENST00000393077(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|mint:Q96AJ9|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001305132.1|refseq:NP_001305134.1|refseq:XP_005269601.1|dip:DIP-44223N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:MZOfyoq6Oe9cFxPKa3ZxWTuPTrI9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q8WVM8	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q8WU76	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-2561361|ensembl:ENSP00000384182|uniprotkb:Q8N5F3|uniprotkb:Q96ED3|uniprotkb:Q8N8H0	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:scfd2_human(display_long)|uniprotkb:SCFD2(gene name)|psi-mi:SCFD2(display_short)|uniprotkb:STXBP1L1(gene name synonym)|uniprotkb:Syntaxin-binding protein 1-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000184178(gene)|ensembl:ENST00000401642(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|refseq:NP_689753.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:TaNn58iCMGPAhs6k76eLY0BuGKM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q7L5Y9	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-10984762|ensembl:ENSP00000302830|uniprotkb:O95285|uniprotkb:Q5JB54|uniprotkb:Q6ZRD6|uniprotkb:Q9NW84|uniprotkb:Q9H9Z4|uniprotkb:Q9BQ11|uniprotkb:Q9H9V6	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:maea_human(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:Cell proliferation-inducing gene 5 protein(gene name synonym)|uniprotkb:EMP(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 10 protein(gene name synonym)|uniprotkb:Macrophage erythroblast attacher(gene name synonym)|uniprotkb:P44EMLP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001017405.1|refseq:NP_001284360.1|refseq:NP_005873.2|ensembl:ENSG00000090316(gene)|ensembl:ENST00000303400(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063|mint:Q7L5Y9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q6NUQ1	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q15836	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q15370	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q14978	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q13190	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q12981	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-4402847|uniprotkb:D3DQM3|uniprotkb:D3DQM4|uniprotkb:D3DQM5|uniprotkb:D3DQM6|uniprotkb:O75622|uniprotkb:O75623|uniprotkb:O75624|uniprotkb:Q6K044|uniprotkb:Q96FG4|ensembl:ENSP00000239215	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:sec20_human(display_long)|uniprotkb:BNIP1(gene name)|psi-mi:BNIP1(display_short)|uniprotkb:NIP1(gene name synonym)|uniprotkb:SEC20L(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 1(gene name synonym)|uniprotkb:Transformation-related gene 8 protein(gene name synonym)|uniprotkb:TRG8(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001196.2|refseq:NP_053581.2|refseq:NP_053582.2|refseq:NP_053583.2|ensembl:ENSG00000113734(gene)|ensembl:ENST00000351486(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0014823"(response to activity)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097194"(execution phase of apoptosis)|interpro:IPR005606(Sec20)|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:Uvkq5jKqo/7O+U7AZkeHn3JAxvc9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q12846	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:Q02880	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-2307774|uniprotkb:Q13600|uniprotkb:Q9UMG8|uniprotkb:Q9UQP8|intact:EBI-28978028|ensembl:ENSP00000264331	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:top2b_human(display_long)|uniprotkb:TOP2B(gene name)|psi-mi:TOP2B(display_short)|uniprotkb:DNA topoisomerase II, beta isozyme(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001059.2|ensembl:ENSP00000264331|ensembl:ENST00000435706|ensembl:ENSP00000396704|refseq:NP_001317629.1|ensembl:ENSG00000077097(gene)|ensembl:ENST00000264331(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007409"(axonogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030900"(forebrain development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR028467|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:Q02880|rcsb pdb:3QX3|rcsb pdb:4G0U|rcsb pdb:4G0V|rcsb pdb:4G0W|rcsb pdb:4J3N|rcsb pdb:5GWI|rcsb pdb:5GWJ|rcsb pdb:5ZAD|rcsb pdb:5ZEN|rcsb pdb:5ZQF|rcsb pdb:5ZRF|reactome:R-HSA-4615885	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:4PxrfQmGIKuMdAy/ArYH9/ItQUQ9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:P51809	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-1052205|uniprotkb:Q53GY7|uniprotkb:Q7Z409|uniprotkb:Q9H4A7|ensembl:ENSP00000286448	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vamp7_human(display_long)|uniprotkb:SYBL1(gene name synonym)|uniprotkb:Synaptobrevin-like protein 1(gene name synonym)|uniprotkb:Tetanus-insensitive VAMP(gene name synonym)|uniprotkb:VAMP7(gene name)|psi-mi:VAMP7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001138621.1|refseq:NP_001172112.1|refseq:NP_005629.1|ensembl:ENSG00000124333(gene)|ensembl:ENST00000286448(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031143"(pseudopodium)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034197"(triglyceride transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|mint:P51809|rcsb pdb:2DMW|reactome:R-HSA-199992|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9020591	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:iGCiTvDrgrPOV7mOfivnbt02zV89606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:P48735	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:P46459	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:P08133	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001146.2|refseq:NP_001180473.1|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008289"(lipid binding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051283"(negative regulation of sequestering of calcium ion)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENSG00000197043(gene)|ensembl:ENST00000354546(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003418"(growth plate cartilage chondrocyte differentiation)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1M9I|reactome:R-HSA-445355	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O75396	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O75379	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-744953|uniprotkb:Q96IY9|uniprotkb:Q96J20|uniprotkb:Q9UEL7|uniprotkb:A2IDD8|ensembl:ENSP00000236192|ensembl:ENSP00000435933	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:vamp4_human(display_long)|uniprotkb:VAMP4(gene name)|psi-mi:VAMP4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001172056.1|refseq:NP_003753.2|ensembl:ENSG00000117533(gene)|ensembl:ENST00000236192(transcript)|ensembl:ENST00000474047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0030133"(transport vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042855|interpro:IPR042887|mint:O75379|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-44226N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:tITvmst+UYk596iJSowMT+R0U/89606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O60499	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-11343362|uniprotkb:Q96AE8|uniprotkb:Q6IAP4|uniprotkb:A6NC41|ensembl:ENSP00000466298	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx10_human(display_long)|uniprotkb:STX10(gene name)|psi-mi:STX10(display_short)|uniprotkb:SYN10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001258540.1|refseq:NP_003756.1|ensembl:ENSG00000104915(gene)|ensembl:ENST00000587230(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|rcsb pdb:4DND|reactome:R-HSA-6811440|dip:DIP-60563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:PV1m5+whDK+Af3FGLEts82P1EyM9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O43752	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-2695795|uniprotkb:Q5VY08|uniprotkb:B2R652|uniprotkb:Q6FH83|intact:EBI-28977663|ensembl:ENSP00000258301|uniprotkb:B4DR17	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx6_human(display_long)|uniprotkb:STX6(gene name)|psi-mi:STX6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSP00000258301|ensembl:ENST00000542060|ensembl:ENSP00000440188|refseq:NP_005810.1|ensembl:ENSG00000135823(gene)|ensembl:ENST00000258301(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:O43752|rcsb pdb:2NPS|rcsb pdb:4J2C|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001273139.1|refseq:XP_016855496.1|dip:DIP-44224N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:g8/HcXvvEY2Pqv8NWy3V+T+jBTY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O15400	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O15155	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-749204|uniprotkb:Q96EA0|ensembl:ENSP00000222547	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:bet1_human(display_long)|uniprotkb:Golgi vesicular membrane-trafficking protein p18(gene name synonym)|uniprotkb:BET1(gene name)|psi-mi:BET1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_005859.1|refseq:NP_001304668.1|ensembl:ENSG00000105829(gene)|ensembl:ENST00000222547(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|rcsb pdb:3EGX|reactome:R-HSA-204005|reactome:R-HSA-6807878|go:"GO:0031201"(SNARE complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:q+HguYhGwObsWqPGNyIVXf/YHO49606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O14662	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-2853548|uniprotkb:B7ZBN3|uniprotkb:O14663|uniprotkb:Q5W086|uniprotkb:A6NN69|uniprotkb:Q9H0Z0|uniprotkb:O60517|uniprotkb:Q9UIX5|uniprotkb:Q5W087|uniprotkb:Q5XKI6|uniprotkb:Q5W084|uniprotkb:B7ZBN1|uniprotkb:B7ZBN2|uniprotkb:O14661|uniprotkb:Q9H1T7|uniprotkb:Q9H1T8|uniprotkb:E1P607|uniprotkb:A6NK32|uniprotkb:A8MPP0|uniprotkb:Q6GMS8|uniprotkb:E1P5M0|ensembl:ENSP00000360183	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:stx16_human(display_long)|uniprotkb:STX16(gene name)|psi-mi:STX16(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001001433.1|refseq:NP_001128245.1|refseq:NP_001191797.1|refseq:NP_003754.2|refseq:NP_001128244.1|dip:DIP-57570N|ensembl:ENSG00000124222(gene)|ensembl:ENST00000371141(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:pJ1TuU8Jl4SqtRPMYNCV0ZO0pRY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O14653	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-4401517|uniprotkb:D3DXJ6|uniprotkb:D3DXJ5|uniprotkb:Q96DA5|uniprotkb:Q9BZZ4|uniprotkb:Q8N4B8|ensembl:ENSP00000492751	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:gosr2_human(display_long)|uniprotkb:GOSR2(gene name)|psi-mi:GOSR2(display_short)|uniprotkb:GS27(gene name synonym)|uniprotkb:27 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:Membrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_001012529.1|refseq:NP_004278.2|refseq:NP_473363.1|ensembl:ENSG00000108433(gene)|ensembl:ENST00000640051(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3EG9|reactome:R-HSA-204005|reactome:R-HSA-381038|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:RWoVhfrHKdtVMlLtb5NRU/R2wRY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:O00161	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:I1VE18	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-21261825	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:i1ve18_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|interpro:IPR011012(Longin-like)|interpro:IPR010908(Longin)|interpro:IPR044565	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:0p6Irp5XWk5S7qQwpQ7z9bMVxe49606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:H0YL12	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-21259817|ensembl:ENSP00000453017	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:h0yl12_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	go:"GO:0005759"(mitochondrial matrix)|ensembl:ENSG00000140374(gene)|ensembl:ENST00000560345(transcript)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR029035|interpro:IPR033947	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:Cw4dRHI2p2B3Ge4EJBFj2UT9b2Q9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:G5E9T8	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-21261813|ensembl:ENSP00000414956	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:g5e9t8_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym)|uniprotkb:Golgi SNAP receptor complex member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	go:"GO:0016021"(integral component of membrane)|interpro:IPR023601|ensembl:ENSG00000108587(gene)|ensembl:ENST00000414833(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:QcuR4o3fGy+b967k1bDPqk5h5809606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P54920	uniprotkb:B1AJQ6	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	intact:EBI-21260301|ensembl:ENSP00000392577	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:b1ajq6_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261831|imex:IM-26691-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	ensembl:ENSG00000117758(gene)|ensembl:ENST00000440806(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rogid:0zq5qvXzoqXybBzDo4meAom6Psc9606	rigid:TQm+1MU3XNa38T6EEunENap3yMU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q6P2Q9	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:I0ot8b3pvieXRI66omFm145sGVA9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q9P258	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q99961	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360	-	-	crc64:6E5BE978BC955077	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q99714	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q92598	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q5C9Z4	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-2685618|uniprotkb:Q96I08|ensembl:ENSP00000275820	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:nom1_human(display_long)|uniprotkb:C7orf3(gene name synonym)|uniprotkb:SGD1 homolog(gene name synonym)|uniprotkb:NOM1(gene name)|psi-mi:NOM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_612409.1|ensembl:ENSG00000146909(gene)|ensembl:ENST00000275820(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0048820"(hair follicle maturation)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:Q5C9Z4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:1LScd95yytIZJ1/UFg9WTUiCmqg9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q32Q12	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-11897132|ensembl:ENSP00000451932	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:q32q12_human(display_long)|uniprotkb:NME1-NME2(gene name)|psi-mi:NME1-NME2(display_short)|uniprotkb:hCG_2001850(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000011052(gene)|ensembl:ENST00000555572(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:F9Z+VsBFIAci0CnyPOHlWo7SinY9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q16576	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q13200	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q13162	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q12874	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:fNjNguUOXqApr46rOAEpTs2geqY9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q08J23	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q08380	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q06830	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:Q02218	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-747213|intact:EBI-1210683|uniprotkb:Q9UDX0|uniprotkb:D3DVL0|uniprotkb:B4E2U9|uniprotkb:E9PBM1|uniprotkb:Q96DD3|ensembl:ENSP00000222673	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:odo1_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_002532.2|refseq:NP_001003941.1|refseq:NP_001158508.1|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0021756"(striatum development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|rcsb pdb:3ERY|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403|ensembl:ENSG00000105953(gene)|ensembl:ENST00000222673(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|dip:DIP-39353N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:B9CSRCmhDYg7n5jSpuDlr2mrxDg9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P63151	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P56192	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|uniprotkb:B3KVK7|ensembl:ENSP00000262027	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|reactome:R-HSA-379716|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|refseq:NP_004981.2|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000166986(gene)|ensembl:ENST00000262027(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|dip:DIP-38164N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P54578	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1048016|uniprotkb:Q53XY5|uniprotkb:B7Z4N8|uniprotkb:J3QRZ5|ensembl:ENSP00000261601	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:ubp14_human(display_long)|uniprotkb:USP14(gene name)|psi-mi:USP14(display_short)|uniprotkb:TGT(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 14(gene name synonym)|uniprotkb:Deubiquitinating enzyme 14(gene name synonym)|uniprotkb:Ubiquitin thioesterase 14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001032411.1|refseq:NP_005142.1|ensembl:ENSG00000101557(gene)|ensembl:ENST00000261601(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0045087"(innate immune response)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR019954|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|mint:P54578|rcsb pdb:2AYN|rcsb pdb:2AYO|rcsb pdb:5GJQ|rcsb pdb:6IIK|rcsb pdb:6IIL|rcsb pdb:6IIM|rcsb pdb:6IIN|rcsb pdb:6LVS|reactome:R-HSA-5689880|go:"GO:0070628"(proteasome binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:5hXfHmHds5nuvdlFYWoB/G6nvmk9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P53621	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P53618	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P49327	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P48444	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P36957	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P27348	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P24534	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P23921	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P22695	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P22234	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:P13639	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:O14929	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14598	uniprotkb:J3KT38	intact:EBI-395044|uniprotkb:A6NEH2|uniprotkb:A8K7S9|uniprotkb:O43842|uniprotkb:Q2PP07|uniprotkb:Q9BU90|uniprotkb:Q9BXI7|uniprotkb:Q9BXI8|uniprotkb:Q9UDV9|uniprotkb:Q9UMU2|uniprotkb:Q53FR5|ensembl:ENSP00000289473	intact:EBI-21261954|ensembl:ENSP00000462785	psi-mi:ncf1_human(display_long)|uniprotkb:NCF1(gene name)|psi-mi:NCF1(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 1(gene name synonym)|uniprotkb:47 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p47-phox(gene name synonym)|uniprotkb:NCF-47K(gene name synonym)|uniprotkb:47 kDa autosomal chronic granulomatous disease protein(gene name synonym)|uniprotkb:Nox-organizing protein 2(gene name synonym)|uniprotkb:Nox organizer 2(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1A(gene name synonym)|uniprotkb:NOXO2(gene name synonym)|uniprotkb:SH3PXD1A(gene name synonym)	psi-mi:j3kt38_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21261968|imex:IM-26691-89	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032010"(phagolysosome)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060264"(regulation of respiratory burst involved in inflammatory response)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR001452(Src homology-3)|interpro:IPR001655(Neutrophil cytosol factor 1)|interpro:IPR001683(Phox-like)|interpro:IPR015039(NADPH oxidase subunit p47Phox, C terminal)|interpro:IPR032136|interpro:IPR034909|interpro:IPR035756|interpro:IPR035757|interpro:IPR036028|interpro:IPR036871|mint:P14598|rcsb pdb:1GD5|rcsb pdb:1K4U|rcsb pdb:1KQ6|rcsb pdb:1NG2|rcsb pdb:1O7K|rcsb pdb:1OV3|rcsb pdb:1UEC|rcsb pdb:1W70|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000158517(gene)|ensembl:ENST00000289473(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|refseq:NP_000256.4|dip:DIP-126N	ensembl:ENSG00000177885(gene)|ensembl:ENST00000582582(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR036028|interpro:IPR036860	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cNIwxrttmz096/m5mr+NRK5D9Nc9606	rogid:0+bAvqQvsurnk4jbEsSYQRfEM9I9606	rigid:4q8RMKV3ws/g5lnYP1VyATnuV1M	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q9Y5M8	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q9BVK6	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q96RT1	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q5JSD2	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q13501	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q13445	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-4310995|ensembl:ENSP00000214869	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:tmed1_human(display_long)|uniprotkb:TMED1(gene name)|psi-mi:TMED1(display_short)|uniprotkb:IL1RL1L(gene name synonym)|uniprotkb:IL1RL1LG(gene name synonym)|uniprotkb:Interleukin-1 receptor-like 1 ligand(gene name synonym)|uniprotkb:Putative T1/ST2 receptor-binding protein(gene name synonym)|uniprotkb:p24 family protein gamma-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_006849.1|ensembl:ENSG00000099203(gene)|ensembl:ENST00000214869(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q13445	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:PQHIGiwN0HhCGcpm1HGn/WF3t9U9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q12792	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q10589	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:Q00325	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	crc64:78714C85931B22D5	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P63151	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P61513	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:0kwO2cVd99FGF2+5FyWo94C83049606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P49755	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P49207	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P40939	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P31689	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P30153	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P24844	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-716193|uniprotkb:Q9BQL9|uniprotkb:Q9BUF9|uniprotkb:Q9H136|uniprotkb:E1P5T6|ensembl:ENSP00000279022	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:myl9_human(display_long)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC1(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2C(gene name synonym)|uniprotkb:20 kDa myosin light chain(gene name synonym)|uniprotkb:MYL9(gene name)|psi-mi:MYL9(display_short)|uniprotkb:MRLC1(gene name synonym)|uniprotkb:MYRL2(gene name synonym)|uniprotkb:MLC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_006088.2|refseq:NP_852667.1|ensembl:ENSG00000101335(gene)|ensembl:ENST00000279022(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0070527"(platelet aggregation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P24844|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-8936459|dip:DIP-60525N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:FeJb0ac0n3hkVmRDnxeGSlL2/A89606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P17987	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P09496	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:P08590	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-3909140|uniprotkb:Q9NRS8|uniprotkb:B2R534|ensembl:ENSP00000292327|ensembl:ENSP00000379210|ensembl:ENSP00000499406|ensembl:ENSP00000499577|ensembl:ENSP00000499624	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:myl3_human(display_long)|uniprotkb:MYL3(gene name)|psi-mi:MYL3(display_short)|uniprotkb:Cardiac myosin light chain 1(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Ventricular/slow twitch myosin alkali light chain(gene name synonym)|uniprotkb:Ventricular myosin alkali light chain(gene name synonym)|uniprotkb:Ventricular myosin light chain 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_000249.1|ensembl:ENSG00000160808(gene)|ensembl:ENST00000292327(transcript)|ensembl:ENST00000395869(transcript)|ensembl:ENST00000653454(transcript)|ensembl:ENST00000654597(transcript)|ensembl:ENST00000662933(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030017"(sarcomere)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P08590|rcsb pdb:5TBY|reactome:R-HSA-390522	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:c6a6WDyl6ICfx4FvSdh2sh8zAaU9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:O95573	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:O15269	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:E7EQ72	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-21262076|ensembl:ENSP00000405845	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:e7eq72_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	ensembl:ENSG00000086598(gene)|ensembl:ENST00000438031(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:tryIfI8sTHTLZhtkOTUEfzwJEJA9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HC29	uniprotkb:B7Z6G4	intact:EBI-7445625|uniprotkb:Q96RH5|uniprotkb:Q96RH8|uniprotkb:Q96RH6|uniprotkb:E2JEQ6|intact:MINT-151071|ensembl:ENSP00000300589	intact:EBI-21262067	psi-mi:nod2_human(display_long)|uniprotkb:IBD1(gene name synonym)|uniprotkb:NOD2(gene name)|psi-mi:NOD2(display_short)|uniprotkb:CARD15(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 15(gene name synonym)|uniprotkb:Inflammatory bowel disease protein 1(gene name synonym)	psi-mi:b7z6g4_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262102|imex:IM-26691-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071445.1|refseq:XP_005256141.1|ensembl:ENSG00000167207(gene)|ensembl:ENST00000300589(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0002253"(activation of immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002710"(negative regulation of T cell mediated immunity)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002732"(positive regulation of dendritic cell cytokine production)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016045"(detection of bacterium)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0005886"(plasma membrane)|go:"GO:0032498"(detection of muramyl dipeptide)|go:"GO:0032500"(muramyl dipeptide binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032701"(negative regulation of interleukin-18 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0006952"(defense response)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007584"(response to nutrient)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046645"(positive regulation of gamma-delta T cell activation)|go:"GO:0009595"(detection of biotic stimulus)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060585"(positive regulation of prostaglandin-endoperoxide synthase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q9HC29|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|refseq:NP_001280486.1|dip:DIP-41998N	go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0017022"(myosin binding)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)	-	comment:mint|comment:homomint|function:"Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)"|function:"Defects in NOD2 are the cause of Blau syndrome (BS) [MIM:186580]. BS is a rare autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash"|function:"Defects in NOD2 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease"|function:"Defects in NOD2 are a cause of susceptibility to ulcerative colitis [MIM:191390]. It is a chronic inflammatory bowel disease. In ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers. Ulcerative colitis is commonly classified as autoimmune disease"|function:"Defects in NOD2 are the cause of early-onset sarcoidosis (EOS) [MIM:609464]. Sarcoidosis is a multiorganic inflammatory disease with unknown etiology, characterized by the histologic features of non-caseating epithelioid granulomas. In childhood, 2 distinct types of sarcoidosis have been described. Usually the disease is detected in older children by chest radiography and the clinical manifestations are characterized by a classical triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS), which usually appears in those younger than 4 years of age, is quite rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement"	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cEF3hnDQW90TWXNDH/uqW6/wMhI9606	rogid:dCvW0uwS4D8+zjT93un5NOx5HTQ9606	rigid:qlMQ5x5XmelqZfsor4Ab1WUYbYU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q9P2R7	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q9NSE4	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q9H9P8	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-11081371|uniprotkb:Q9BRR1|ensembl:ENSP00000267436|ensembl:ENSP00000405559	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:l2hdh_human(display_long)|uniprotkb:L2HGDH(gene name)|psi-mi:L2HGDH(display_short)|uniprotkb:C14orf160(gene name synonym)|uniprotkb:Duranin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_079160.1|refseq:XP_005268132.1|ensembl:ENSG00000087299(gene)|ensembl:ENST00000267436(transcript)|ensembl:ENST00000421284(transcript)|go:"GO:0003973"("(S)-2-hydroxy-acid oxidase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0047545"(2-hydroxyglutarate dehydrogenase activity)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188|reactome:R-HSA-880009	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:EMg3mk/BoaMCMi3AegPe/uX1/149606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q9BXW7	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-4399500|uniprotkb:B2RCK5|uniprotkb:Q9BXW8|uniprotkb:Q9NWA8|uniprotkb:Q9NX41|ensembl:ENSP00000337358	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:hdhd5_human(display_long)|uniprotkb:HDHD5(gene name)|psi-mi:HDHD5(display_short)|uniprotkb:CECR5(gene name synonym)|uniprotkb:Cat eye syndrome critical region protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_060299.4|refseq:NP_149061.1|ensembl:ENSG00000069998(gene)|ensembl:ENST00000336737(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|interpro:IPR006353(HAD-superfamily hydrolase, subfamily IIA, CECR5)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR029621|interpro:IPR036412|mint:Q9BXW7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:INkCPE3PGW5PVO8j4245B1F99HU9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q96C36	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q969Z0	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q969S9	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-2371750|uniprotkb:Q8WYI0|uniprotkb:A0AR28|uniprotkb:Q8N6D8|uniprotkb:Q9H6Z1|intact:EBI-28986334|ensembl:ENSP00000296805|ensembl:ENSP00000427004	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:rrf2m_human(display_long)|uniprotkb:GFM2(gene name)|psi-mi:GFM2(display_short)|uniprotkb:EFG2(gene name synonym)|uniprotkb:Elongation factor G 2, mitochondrial(gene name synonym)|uniprotkb:Elongation factor G2(gene name synonym)|uniprotkb:MSTP027(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_115756.2|refseq:NP_733781.1|refseq:NP_733792.1|ensembl:ENST00000345239|ensembl:ENSP00000296804|ensembl:ENST00000427854|ensembl:ENSP00000405808|ensembl:ENSP00000427004|ensembl:ENSP00000296805|refseq:NP_001268231.1|refseq:XP_016865475.1|dip:DIP-53437N|ensembl:ENSG00000164347(gene)|ensembl:ENST00000296805(transcript)|ensembl:ENST00000509430(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006414"(translational elongation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0070126"(mitochondrial translational termination)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR030851|interpro:IPR031157|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|mint:Q969S9|rcsb pdb:7L20|rcsb pdb:7NSH|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:tDdVCBcztI95aArJCyypUgUrWOw9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q8WUY1	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1170414|uniprotkb:Q8NBN2|uniprotkb:Q9NYI2|uniprotkb:B2RDN6|intact:EBI-2563242|ensembl:ENSP00000338607	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:them6_human(display_long)|uniprotkb:THEM6(gene name)|psi-mi:THEM6(display_short)|uniprotkb:C8orf55(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSCD75(gene name synonym)|uniprotkb:Thioesterase superfamily member 6(gene name synonym)|uniprotkb:PSEC0098(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_057731.1|ensembl:ENSG00000130193(gene)|ensembl:ENST00000336138(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR029069	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:VCZRUm2WiwLdWnKB8jTuOvLy+4A9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q8NI60	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q7L7V1	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-2807297|uniprotkb:Q9NV74|uniprotkb:Q96NY1|uniprotkb:Q9NVJ7|uniprotkb:Q9NSL5|uniprotkb:Q9H769|uniprotkb:Q5T3L5|uniprotkb:Q9BUN0|uniprotkb:Q5T3L0|uniprotkb:A8MSV2|uniprotkb:Q49AG5|uniprotkb:D3DRF9|ensembl:ENSP00000284690	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:dhx32_human(display_long)|uniprotkb:DHX32(gene name)|psi-mi:DHX32(display_short)|uniprotkb:DDX32(gene name synonym)|uniprotkb:DEAD/H box 32(gene name synonym)|uniprotkb:DEAD/H helicase-like protein 1(gene name synonym)|uniprotkb:DEAH box protein 32(gene name synonym)|uniprotkb:HuDDX32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_060650.2|refseq:XP_016871893.1|refseq:XP_016871894.1|ensembl:ENSG00000089876(gene)|ensembl:ENST00000284690(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:IQFcD75pd5R0uajIotdMRpGXVeI9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q6UB35	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1046835|intact:EBI-28986171|ensembl:ENSP00000356290|uniprotkb:Q2TBF3|uniprotkb:Q8WVW0|uniprotkb:Q96HG8|uniprotkb:Q9H789|uniprotkb:Q9UFU8	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:c1tm_human(display_long)|uniprotkb:MTHFD1L(gene name)|psi-mi:MTHFD1L(display_short)|uniprotkb:FTHFSDC1(gene name synonym)|uniprotkb:Formyltetrahydrofolate synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000120254(gene)|ensembl:ENST00000367321(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006760"(folic acid-containing compound metabolic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0015942"(formate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR027417|interpro:IPR036291|reactome:R-HSA-196757|refseq:NP_001229696.1|refseq:NP_001229697.1|refseq:NP_001229698.1|refseq:NP_056255.2|ensembl:ENST00000367307|ensembl:ENSP00000356276|ensembl:ENSP00000356290	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:lJRND1kcMEF99+fT1b+X8hfuLHM9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q5T160	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1050546|uniprotkb:Q96FU5|uniprotkb:Q9H8K8|uniprotkb:B2RDT7|ensembl:ENSP00000358549	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:syrm_human(display_long)|uniprotkb:RARS2(gene name)|psi-mi:RARS2(display_short)|uniprotkb:RARSL(gene name synonym)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_064716.2|ensembl:ENSG00000146282(gene)|ensembl:ENST00000369536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q5T160|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:jslLCkjYCriiVlR94nHAhNIYVeY9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q5JTZ9	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q16822	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780|ensembl:ENSP00000494919|uniprotkb:B4DW73	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_001018083.2|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0042594"(response to starvation)|go:"GO:0046327"(glycerol biosynthetic process from pyruvate)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|go:"GO:0030145"(manganese ion binding)|ensembl:ENSG00000100889(gene)|ensembl:ENSG00000285241(gene)|ensembl:ENST00000216780(transcript)|ensembl:ENST00000645217(transcript)|go:"GO:0004611"(phosphoenolpyruvate carboxykinase activity)|go:"GO:0004613"("phosphoenolpyruvate carboxykinase (GTP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019543"(propionate catabolic process)|refseq:NP_004554.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:Q08380	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P54886	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P53597	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P49411	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P42765	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P36776	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-357448|ensembl:ENSP00000353826|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_001263408.1|go:"GO:0070407"(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|mint:P36776|rcsb pdb:2X36|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070182"(DNA polymerase binding)|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|ensembl:ENSG00000196365(gene)|ensembl:ENST00000360614(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0009725"(response to hormone)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|refseq:NP_001263409.1|refseq:NP_004784.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P34897	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P32322	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P30520	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1042898|uniprotkb:Q96EG7|ensembl:ENSP00000355493|uniprotkb:B1AQM5	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:pura2_human(display_long)|uniprotkb:ADSS2(gene name)|psi-mi:ADSS2(display_short)|uniprotkb:ADSS(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, acidic isozyme(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, liver isozyme(gene name synonym)|uniprotkb:IMP--aspartate ligase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000035687(gene)|ensembl:ENST00000366535(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002376"(immune system process)|go:"GO:0004019"(adenylosuccinate synthase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071257"(cellular response to electrical stimulus)|interpro:IPR001114(Adenylosuccinate synthetase)|interpro:IPR018220|interpro:IPR027417|interpro:IPR027529|interpro:IPR033128|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|mint:P30520|rcsb pdb:2V40|reactome:R-HSA-73817|refseq:NP_001117.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:Tyydt3Z/JHGYtfY9oc9XfFkDguM9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:P30042	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:O75616	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-6393536|ensembl:ENSP00000254928|uniprotkb:B3KN21|uniprotkb:C9JEC6|uniprotkb:O75617|uniprotkb:Q8WUY4|uniprotkb:Q96LE2|uniprotkb:Q96TC0	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:eral1_human(display_long)|uniprotkb:ERAL1(gene name)|psi-mi:ERAL1(display_short)|uniprotkb:HERA(gene name synonym)|uniprotkb:Conserved ERA-like GTPase(gene name synonym)|uniprotkb:ERA-W(gene name synonym)|uniprotkb:ERA-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000132591(gene)|ensembl:ENST00000254928(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005662(GTP-binding protein Era)|interpro:IPR006073(GTP1/OBG)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR027417|interpro:IPR030388|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_005693.1|refseq:NP_001304914.1|refseq:NP_001304915.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:2usCrRc4/GbXG5Ft8GY61w+rGds9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:O75306	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:O43837	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:A8MXV4	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-11350801|ensembl:ENSP00000380251	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:nud19_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 19(gene name synonym)|uniprotkb:NUDT19(gene name)|psi-mi:NUDT19(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	refseq:NP_001099040.1|ensembl:ENSG00000213965(gene)|ensembl:ENST00000397061(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0010945"(CoA pyrophosphatase activity)|go:"GO:0015938"(coenzyme A catabolic process)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0044580"(butyryl-CoA catabolic process)|go:"GO:1901289"(succinyl-CoA catabolic process)|go:"GO:1902858"(propionyl-CoA metabolic process)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR039121|reactome:R-HSA-390918|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:nSyCFhGmUMc1wbmmLp6RZvUojaM9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0P0	uniprotkb:A3KMH1	intact:EBI-3918356|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262179|imex:IM-26691-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036412|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|interpro:IPR023214|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|refseq:NP_001002009.1|go:"GO:0000166"(nucleotide binding)|go:"GO:0000215"(tRNA 2'-phosphotransferase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0051607"(defense response to virus)|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:XP_011513711.1|mint:Q9H0P0	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	rigid:KUorFFvuGZSN20iamMINUth9mtw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P35249	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P43304	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-7600203|uniprotkb:Q59FR1|intact:MINT-4530883|uniprotkb:Q9HAP9|uniprotkb:A8K4V0|uniprotkb:B3KSA9|ensembl:ENSP00000308610|ensembl:ENSP00000386425|ensembl:ENSP00000386626|ensembl:ENSP00000409708	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:gpdm_human(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:mtGPD(gene name synonym)|uniprotkb:mitohondrial glycerophosphate dehydrogenase gene(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:XP_016859319.1|refseq:XP_011509279.1|refseq:NP_001076581.2|refseq:NP_000399.3|refseq:XP_005246526.1|ensembl:ENSG00000115159(gene)|ensembl:ENST00000310454(transcript)|ensembl:ENST00000409674(transcript)|ensembl:ENST00000409861(transcript)|ensembl:ENST00000438166(transcript)|go:"GO:0004368"("glycerol-3-phosphate dehydrogenase (quinone) activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006127"(glycerophosphate shuttle)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0052591"("sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity")|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR031656|interpro:IPR036188|interpro:IPR038299|reactome:R-HSA-1483166|reactome:R-HSA-163560	-	-	comment:mint|comment:homomint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:PsG9Eo7dfk8l+vDJl6d4WfEST849606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:E9PRG8	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-11324775|ensembl:ENSP00000432523|intact:EBI-21262272|uniprotkb:A0A0B4J220	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:ck098_human(display_long)|uniprotkb:C11orf98(gene name)|psi-mi:C11orf98(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_001273015.1|ensembl:ENSG00000278615(gene)|ensembl:ENST00000524958(transcript)|interpro:IPR037691|mint:E9PRG8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:VfLIp/LTQj4cvxS0emale/+FWJU9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9Y490	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:C7FGaR2291KB6hBSloee5L8lYgA9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9Y3C1	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9UN86	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9UMS4	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-395746|ensembl:ENSP00000227524	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9NZM5	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9NVU7	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1043768|uniprotkb:Q32Q11|uniprotkb:Q68D52|uniprotkb:Q7Z5U4|uniprotkb:Q9H831|uniprotkb:Q9H9P6|ensembl:ENSP00000348596	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:sda1_human(display_long)|uniprotkb:SDAD1(gene name)|psi-mi:SDAD1(display_short)|uniprotkb:SDA1 domain-containing protein 1(gene name synonym)|uniprotkb:Nucleolar protein 130(gene name synonym)|uniprotkb:NUC130(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_060585.2|ensembl:ENSG00000198301(gene)|ensembl:ENST00000356260(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0015031"(protein transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR007949(SDA1)|interpro:IPR012977(Region of unknown function, nucleolar NUC130/133, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027312|refseq:XP_005263162.1|refseq:NP_001275912.1|refseq:NP_001275913.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:BdU6Lfg2n/VgrR2SDw2idumu5WQ9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9NVN8	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-746682|ensembl:ENSP00000338573|ensembl:ENSP00000354091|ensembl:ENSP00000501411|ensembl:ENSP00000501441|ensembl:ENSP00000501452	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:gnl3l_human(display_long)|uniprotkb:GNL3L(gene name)|psi-mi:GNL3L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_001171748.1|refseq:NP_061940.1|ensembl:ENSG00000130119(gene)|ensembl:ENST00000336470(transcript)|ensembl:ENST00000360845(transcript)|ensembl:ENST00000674225(transcript)|ensembl:ENST00000674311(transcript)|ensembl:ENST00000674498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR023179|interpro:IPR027417|interpro:IPR030378	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:EIfOgdBUzXC0ujJVM3TnMkiUWNI9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9NQT5	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9NPE3	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1642169|ensembl:ENSP00000332198	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:nop10_human(display_long)|uniprotkb:NOLA3(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:Nucleolar protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_061118.1|dip:DIP-40092N|ensembl:ENSG00000182117(gene)|ensembl:ENST00000328848(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016604"(nuclear body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|mint:Q9NPE3|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:gBAwyGcfJTBMf8Q+fQZ/fDcPEBc9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9BZE4	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:wTcBrIj6c27um4RnJH81grRgutc9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q9BRT6	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-741396|ensembl:ENSP00000266604|ensembl:ENSP00000437372|uniprotkb:Q3B766	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:llph_human(display_long)|uniprotkb:LLPH(gene name)|psi-mi:LLPH(display_short)|uniprotkb:C12orf31(gene name synonym)|uniprotkb:Protein LAPS18-like(gene name synonym)|uniprotkb:cPERP-G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_115714.1|ensembl:ENSG00000139233(gene)|ensembl:ENST00000266604(transcript)|ensembl:ENST00000446587(transcript)|go:"GO:0001099"(basal RNA polymerase II transcription machinery binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0097484"(dendrite extension)|interpro:IPR018784|rcsb pdb:6LSS|rcsb pdb:6LU8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:VeZ4vf0MCcXIdjewPonPDz1vV709606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q99459	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q969S3	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-2687480|ensembl:ENSP00000310042	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_219482.1|ensembl:ENSG00000173545(gene)|ensembl:ENST00000308683(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q14444	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q13823	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:Q01780	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P62891	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P49736	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P42285	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P16401	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-5327611|uniprotkb:Q14529|uniprotkb:Q3MJ42|ensembl:ENSP00000330074	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:h15_human(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1F5(gene name synonym)|uniprotkb:HIST1H1B(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_005313.1|ensembl:ENSG00000184357(gene)|ensembl:ENST00000331442(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0050821"(protein stabilization)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2FE2|rcsb pdb:2RHI|reactome:R-HSA-140342|reactome:R-HSA-2559584|go:"GO:0000792"(heterochromatin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:b81Z7VA09Na0XXDfR0HtaZmq1g89606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:P05386	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:K7ERC4	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-21261583|ensembl:ENSP00000468198	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:k7erc4_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	ensembl:ENSG00000173786(gene)|ensembl:ENST00000587679(transcript)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0042470"(melanosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:/Vn3QzpFFSK47wQIhlyDko6Eu389606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:A8K3Q9	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-10174314	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:a8k3q9_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	interpro:IPR041985|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:j616/CNgbYEAH+NvWkfjXpZWqo89606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y6K5	uniprotkb:A6NLN1	intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928	intact:EBI-21260952|ensembl:ENSP00000342332	psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name)	psi-mi:a6nln1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:hCG_20560(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262283|imex:IM-26691-125	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733	interpro:IPR021790|interpro:IPR034798|interpro:IPR035001|ensembl:ENSG00000011304(gene)|ensembl:ENST00000350092(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035000|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606	rogid:u1acIbk3sUtk1Xz36eSvfwApxx09606	rigid:2ZbJ8DZI43NnhC8MXzXmSEwlXOc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y6M1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:k45UViReMAxCv2cu7+tx+auevQc9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y5J1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-592816|uniprotkb:Q9H4N6|ensembl:ENSP00000225298	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:utp18_human(display_long)|uniprotkb:WD repeat-containing protein 50(gene name synonym)|uniprotkb:UTP18(gene name)|psi-mi:UTP18(display_short)|uniprotkb:CGI-48(orf name)|uniprotkb:CDABP0061(orf name)|uniprotkb:WDR50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_057085.2|ensembl:ENSG00000011260(gene)|ensembl:ENST00000225298(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9Y5J1|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:l873IUyfCql4N9VelHPuUEqpzRY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y3Y2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9|ensembl:ENSP00000357683	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001304006.1|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|ensembl:ENSG00000160679(gene)|ensembl:ENST00000368694(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y3B9	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1055610|intact:EBI-28979625|ensembl:ENSP00000355899	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rrp15_human(display_long)|uniprotkb:Ribosomal RNA-processing protein 15(gene name synonym)|uniprotkb:RRP15(gene name)|psi-mi:RRP15(display_short)|uniprotkb:KIAA0507(gene name synonym)|uniprotkb:CGI-115(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSP00000355899|refseq:NP_057136.2|ensembl:ENSG00000067533(gene)|ensembl:ENST00000366932(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR012459(Protein of unknown function DUF1665)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:EJQFG76HKEYeJ6LwFd5zaUmoScw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y383	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y2R5	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1046443|ensembl:ENSP00000285298|uniprotkb:Q86X15	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rt17_human(display_long)|uniprotkb:MRPS17(gene name)|psi-mi:MRPS17(display_short)|uniprotkb:RPMS17(gene name synonym)|uniprotkb:HSPC011(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS17m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000239789(gene)|ensembl:ENST00000285298(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039193|mint:Q9Y2R5|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|reactome:R-HSA-5389840|rcsb pdb:6ZSB|reactome:R-HSA-5419276|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|refseq:NP_057053.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:UDEpLcg5pGMMYvvc72HnPf9169U9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9Y221	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-749003|uniprotkb:Q9NZZ0|uniprotkb:B2RD04|ensembl:ENSP00000254940	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:nip7_human(display_long)|uniprotkb:KD93(gene name synonym)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nucleolar pre-rRNA processing protein NIP7(gene name synonym)|uniprotkb:CGI-37(orf name)|uniprotkb:HSPC031(orf name)|uniprotkb:HSPC180(orf name)|uniprotkb:OK/SW-cl.76(orf name)|uniprotkb:OK/SW-cl.78(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001186363.1|refseq:NP_057185.1|ensembl:ENSG00000132603(gene)|ensembl:ENST00000254940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|mint:Q9Y221|rcsb pdb:1SQW|rcsb pdb:1T5Y|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:912ZyupB0CxH5w23chPh3IIICmY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9UL15	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9UJV9	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9UHI6	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9UBS4	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NZT1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NZI8	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NZB2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NW13	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NUL3	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-722938|uniprotkb:Q6AHY7|uniprotkb:Q96HM0|uniprotkb:Q96HM1|uniprotkb:Q9NVI5|uniprotkb:Q9UGG6|uniprotkb:A0A0A0MTC5|uniprotkb:E9PF26|uniprotkb:B7Z1I6|uniprotkb:B7Z292|uniprotkb:B7Z8B4|uniprotkb:E7ER74|uniprotkb:E9PEI3|uniprotkb:E9PF50|ensembl:ENSP00000428756	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:stau2_human(display_long)|uniprotkb:STAU2(gene name)|psi-mi:STAU2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001157852.1|refseq:NP_001157853.1|refseq:NP_001157854.1|refseq:NP_001157855.1|refseq:NP_001157856.1|refseq:NP_001157857.1|refseq:NP_055208.2|ensembl:ENSG00000040341(gene)|ensembl:ENST00000524300(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044464|interpro:IPR044473|interpro:IPR044474|interpro:IPR044476	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:iFcd8pLhQK+8ihFUCf4sl2f0bgw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NQT5	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NPA8	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9HCE1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9H845	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9H7B2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9H6S0	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1057466|uniprotkb:B2RP66|ensembl:ENSP00000161863	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ytdc2_human(display_long)|uniprotkb:YTHDC2(gene name)|psi-mi:YTHDC2(display_short)|uniprotkb:YTH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_073739.3|ensembl:ENSG00000047188(gene)|ensembl:ENST00000161863(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007286"(spermatid development)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048599"(oocyte development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051729"(germline cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031083|interpro:IPR034083|interpro:IPR036770|interpro:IPR036867|mint:Q9H6S0|rcsb pdb:2YU6|rcsb pdb:6K6U|refseq:XP_016865219.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:8J8b1Q3F6rfXUwtp7EOeU2y89Lc9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9GZR7	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9BUJ2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9BQ39	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q99832	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q99729	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q99575	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q96SI9	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-740355|uniprotkb:Q32NB9|uniprotkb:Q9BUE1|uniprotkb:Q9BXG4|uniprotkb:Q9H0B4|uniprotkb:Q9H7V1|uniprotkb:Q9NUK4|ensembl:ENSP00000321347|ensembl:ENSP00000415968	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:strbp_human(display_long)|uniprotkb:STRBP(gene name)|psi-mi:STRBP(display_short)|uniprotkb:SPNR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001164608.1|refseq:NP_060857.2|ensembl:ENSG00000165209(gene)|ensembl:ENST00000348403(transcript)|ensembl:ENST00000447404(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008017"(microtubule binding)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR030446|interpro:IPR043519|interpro:IPR044472|rcsb pdb:2DMY|refseq:XP_016870383.1|refseq:XP_016870384.1|refseq:XP_016870385.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:xVEZqCqBcH0MBB1Ar9SU+9Yhsbs9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q96QR8	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2880222|ensembl:ENSP00000379051|uniprotkb:A4D2L7	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:purb_human(display_long)|uniprotkb:PURB(gene name)|psi-mi:PURB(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000146676(gene)|ensembl:ENST00000395699(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|mint:Q96QR8|go:"GO:0046332"(SMAD binding)|refseq:NP_150093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:C29M3TyoXYI3mhCdaSsYC2kt8ek9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q96KR1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q96GQ7	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-722051|uniprotkb:A0AVB6|uniprotkb:Q5VXM7|uniprotkb:Q8WYG4|uniprotkb:Q969N7|uniprotkb:Q96F57|uniprotkb:Q96L97|uniprotkb:Q9BWY9|uniprotkb:Q9BXF0|uniprotkb:Q9H990|uniprotkb:Q9NWU3|uniprotkb:Q9P0C2|uniprotkb:Q9UGD6|uniprotkb:B7ZLY1	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx27_human(display_long)|uniprotkb:DEAD box protein 27(gene name synonym)|uniprotkb:DDX27(gene name)|psi-mi:DDX27(display_short)|uniprotkb:RHLP(gene name synonym)|uniprotkb:cPERP-F(gene name synonym)|uniprotkb:HSPC259(orf name)|uniprotkb:PP3241(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	interpro:IPR027417|refseq:NP_060365.7|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|mint:Q96GQ7|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Z4Dm6lxXyqB18+uPxROJszLWYdE9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q92900	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q92615	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8WTT2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2512539|ensembl:ENSP00000360412|uniprotkb:Q9H9D8|uniprotkb:Q9H5M6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:noc3l_human(display_long)|uniprotkb:NOC3L(gene name)|psi-mi:NOC3L(display_short)|uniprotkb:AD24(gene name synonym)|uniprotkb:C10orf117(gene name synonym)|uniprotkb:FAD24(gene name synonym)|uniprotkb:NOC3-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 3-like protein(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR005612(CBF)|interpro:IPR011501(Nucleolar complex-associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016903(Nucleolar complex-associated protein 3)|mint:Q8WTT2|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000173145(gene)|ensembl:ENST00000371361(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|refseq:NP_071896.8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:s78IiBuQQjc0emiM/UkEMhzThVc9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8TEQ6	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8TDD1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:VzxEkRaOIND08jGJk3yyoztesjo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8NI36	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2512413|ensembl:ENSP00000423067|ensembl:ENSP00000479950|uniprotkb:A2RUS4|uniprotkb:Q8N1Q2|uniprotkb:Q68E02	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:wdr36_human(display_long)|uniprotkb:WDR36(gene name)|psi-mi:WDR36(display_short)|uniprotkb:T-cell activation WD repeat-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000134987(gene)|ensembl:ENST00000506538(transcript)|ensembl:ENST00000612402(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0050896"(response to stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|refseq:NP_644810.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:97Qc0ehUPTjCBcn3gjr0FY8Nnus9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8N9T8	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8N163	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q8IXB1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q86V81	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-347640|uniprotkb:O43672	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q7Z2W4	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q6PK04	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-714654|ensembl:ENSP00000329360|ensembl:ENSP00000458884	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:cc137_human(display_long)|uniprotkb:CCDC137(gene name)|psi-mi:CCDC137(display_short)|uniprotkb:cPERP-B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_954981.1|ensembl:ENSG00000185298(gene)|ensembl:ENST00000329214(transcript)|ensembl:ENST00000575223(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR026680|mint:Q6PK04	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:e64Y/4oJpFqmYZEO1lOUHeLwy0I9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q6P158	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1051531|uniprotkb:Q53SI4|uniprotkb:Q6P9G1|uniprotkb:Q7Z6H3|uniprotkb:Q8NG17|uniprotkb:Q96M33|uniprotkb:A2RRC7|ensembl:ENSP00000405111	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:dhx57_human(display_long)|uniprotkb:DEAH box protein 57(gene name synonym)|uniprotkb:DHX57(gene name)|psi-mi:DHX57(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_945314.1|refseq:XP_011531456.1|refseq:XP_011531457.1|ensembl:ENSG00000163214(gene)|ensembl:ENST00000457308(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006575(RWD)|interpro:IPR007502(Helicase-associated region)|interpro:IPR009060(UBA-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR027417|interpro:IPR036855|interpro:IPR041367|interpro:IPR042615|mint:Q6P158	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:+srrYp6+3YKAvSOr8wkq0Vcjsvo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q6NZY4	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q6FHM6	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21262418	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:q6fhm6_human(display_long)|uniprotkb:NHP2L1(gene name)|psi-mi:NHP2L1(display_short)|uniprotkb:hCG_41538(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0007338"(single fertilization)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0042254"(ribosome biogenesis)|refseq:NP_001003796.1|refseq:NP_004999.1|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR029064|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR004037(Ribosomal protein L7Ae)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:ZMkqsDfMCrTlT/kJxillOA8839E9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q6DKI1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1052408|uniprotkb:Q5TFZ5|uniprotkb:Q6PEK3|uniprotkb:A8K7D4|uniprotkb:B7Z652|ensembl:ENSP00000346063|ensembl:ENSP00000418221	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rl7l_human(display_long)|uniprotkb:RPL7L1(gene name)|psi-mi:RPL7L1(display_short)|uniprotkb:Large ribosomal subunit protein uL30-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_940888.3|ensembl:ENSG00000146223(gene)|ensembl:ENST00000304734(transcript)|ensembl:ENST00000493763(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:Q6DKI1|refseq:XP_016866269.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:hB4ePwPQxahWRS9OEEfq1nL/lk09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q5W012	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21258084|ensembl:ENSP00000395448	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:q5w012_human(display_long)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000134453(gene)|ensembl:ENST00000437845(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR040052	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:61YxKA3gAuN6QCpAFyBysWjmYX89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q5QPM0	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21262411|ensembl:ENSP00000327522	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:q5qpm0_human(display_long)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000125970(gene)|ensembl:ENST00000333552(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:xD9IkARBjlMfIyiiB2xbgBgrTFo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q5BKZ1	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2560158|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|ensembl:ENSP00000340796|uniprotkb:A8MYX1|uniprotkb:B4E179	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_892020.1|refseq:NP_892021.1|refseq:XP_011539592.1|ensembl:ENSG00000162664(gene)|ensembl:ENST00000340281(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044609"(DBIRD complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q53G47	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21262404	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:q53g47_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0006376"(mRNA splice site selection)|go:"GO:0005685"(U1 snRNP)|go:"GO:0003729"(mRNA binding)|interpro:IPR004882(LUC7 related)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:w61VEyTmEJQuiZVLFC/j6siDV/w9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q4G0J3	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q3ZCM7	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q1KMD3	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1059150|uniprotkb:Q8N3B3|ensembl:ENSP00000301785	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hnrl2_human(display_long)|uniprotkb:HNRNPUL2(gene name)|psi-mi:HNRNPUL2(display_short)|uniprotkb:HNRPUL2(gene name synonym)|uniprotkb:Scaffold-attachment factor A2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001073027.1|ensembl:ENSG00000214753(gene)|ensembl:ENST00000301785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q1KMD3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:TOoq1VTfNNzysqSyPH9MHLbSKPA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q16637	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q15717	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q15477	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-373226|uniprotkb:O15005|uniprotkb:Q12902|uniprotkb:Q15476|intact:EBI-1058949|uniprotkb:Q5ST66|ensembl:ENSP00000364543|ensembl:ENSP00000372827|ensembl:ENSP00000394400|ensembl:ENSP00000399530|ensembl:ENSP00000400626|ensembl:ENSP00000412310	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:skiv2_human(display_long)|uniprotkb:SKIV2L(gene name)|psi-mi:SKIV2L(display_short)|uniprotkb:DDX13(gene name synonym)|uniprotkb:SKI2W(gene name synonym)|uniprotkb:SKIV2(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:Helicase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_008860.4|ensembl:ENSG00000204351(gene)|ensembl:ENSG00000206353(gene)|ensembl:ENSG00000223493(gene)|ensembl:ENSG00000225737(gene)|ensembl:ENSG00000228896(gene)|ensembl:ENSG00000232616(gene)|ensembl:ENST00000375394(transcript)|ensembl:ENST00000383336(transcript)|ensembl:ENST00000412823(transcript)|ensembl:ENST00000421789(transcript)|ensembl:ENST00000429465(transcript)|ensembl:ENST00000448219(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|interpro:IPR040801|mint:Q15477|reactome:R-HSA-390471|reactome:R-HSA-429958	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:+42a3/XPqsM8hc3qP2M9n/pZ+bY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q15397	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q15050	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q15020	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-308619|uniprotkb:Q2M2H0|uniprotkb:Q58F06|uniprotkb:Q8IUS1|uniprotkb:Q96J95|uniprotkb:A8K2E4|uniprotkb:B7ZKM0|ensembl:ENSP00000449386|intact:EBI-11138149	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:sart3_human(display_long)|uniprotkb:KIAA0156(gene name synonym)|uniprotkb:SART3(gene name)|psi-mi:SART3(display_short)|uniprotkb:TIP110(gene name synonym)|uniprotkb:Tat-interacting protein of 110 kDa(gene name synonym)|uniprotkb:p110 nuclear RNA-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000075856(gene)|ensembl:ENST00000546815(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|mint:Q15020|rcsb pdb:2DO4|rcsb pdb:5CTQ|rcsb pdb:5CTR|rcsb pdb:5CTT|rcsb pdb:5JJW|rcsb pdb:5JJX|rcsb pdb:5JPZ|refseq:NP_055521.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:/71mWOMJti/LCvNo2WjCAmIYUCk9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q14692	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2513630|ensembl:ENSP00000363642|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000165733(gene)|ensembl:ENST00000374518(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|refseq:XP_011538704.1|refseq:NP_055568.3|refseq:XP_005271903.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q14684	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13868	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13601	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13310	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13263	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13243	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13151	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q13015	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-6269719|ensembl:ENSP00000357917	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q12926	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-11285353|uniprotkb:D3DRK3|uniprotkb:Q13235|uniprotkb:Q59G15|uniprotkb:Q8NEM4|uniprotkb:Q9H1Q8|ensembl:ENSP00000369460|ensembl:ENSP00000380479|ensembl:ENSP00000440998	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:elav2_human(display_long)|uniprotkb:ELAVL2(gene name)|psi-mi:ELAVL2(display_short)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:HUB(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Hel-N1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001164666.1|refseq:NP_001164668.1|refseq:NP_004423.2|ensembl:ENSG00000107105(gene)|ensembl:ENST00000380117(transcript)|ensembl:ENST00000397312(transcript)|ensembl:ENST00000544538(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016869908.1|refseq:XP_016869909.1|refseq:XP_016869910.1|refseq:XP_016869911.1|refseq:XP_016869912.1|refseq:XP_016869913.1|refseq:XP_016869914.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Z17PDyoxDFJbfrFlvD3xS91rtLk9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q05519	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1051785|uniprotkb:Q5T758|uniprotkb:Q8IWE6|ensembl:ENSP00000359988	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:srs11_human(display_long)|uniprotkb:Arginine-rich 54 kDa nuclear protein(gene name synonym)|uniprotkb:SRSF11(gene name)|psi-mi:SRSF11(display_short)|uniprotkb:SFRS11(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_004759.1|refseq:NP_001177916.1|refseq:XP_011540729.1|ensembl:ENSG00000116754(gene)|ensembl:ENST00000370950(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034447|interpro:IPR035979|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:XP_016858301.1|refseq:XP_016858302.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:F6QVk0M0PqxLXIA1dgWyoFbwFHE9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q00839	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q00577	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1045860|ensembl:ENSP00000332706|ensembl:ENSP00000499133	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:pura_human(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:PURA(gene name)|psi-mi:PURA(display_short)|uniprotkb:PUR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_005850.1|ensembl:ENSG00000185129(gene)|ensembl:ENST00000331327(transcript)|ensembl:ENST00000651386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:Q00577	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:4NuTKCFE1X+wdaAs+0Brd8IsFS89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P78371	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P67809	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P62306	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P62304	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P57678	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P56182	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P51991	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P50991	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P50990	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P49368	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P46087	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P42696	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2954772|ensembl:ENSP00000386226|uniprotkb:Q8N2Z8|uniprotkb:Q9H5A1|uniprotkb:A8K8J7	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rbm34_human(display_long)|uniprotkb:RBM34(gene name)|psi-mi:RBM34(display_short)|uniprotkb:KIAA0117(gene name synonym)|uniprotkb:RNA-binding motif protein 34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000188739(gene)|ensembl:ENST00000408888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR034220|interpro:IPR034221|interpro:IPR035979|mint:P42696|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_055829.2|refseq:NP_001333667.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:YrlnOTpyzg9F+4ZaZpLMfq4T4ts9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P40227	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P26196	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P17066	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P16989	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P11940	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P08621	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P05455	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P02788	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:B1PKZ2	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-5327925|uniprotkb:O19673|uniprotkb:O19695|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43907|uniprotkb:O77938|uniprotkb:O98010|uniprotkb:P10315|uniprotkb:P79505|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9TQG7|uniprotkb:Q9TQN5|uniprotkb:Q9UIN2	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:1a68_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Aw-68(gene name synonym)|uniprotkb:HLA class I histocompatibility antigen, A-28 alpha chain(gene name synonym)|uniprotkb:MHC class I antigen A*68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	rcsb pdb:4HWZ|rcsb pdb:4HX1|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009986"(cell surface)|go:"GO:0030881"(beta-2-microglobulin binding)|rcsb pdb:6EI2|uniprotkb:P01891(see-also)|go:"GO:0042612"(MHC class I protein complex)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1HSB|rcsb pdb:1TMC|rcsb pdb:2HLA|ensembl:ENST00000457879|rcsb pdb:4I48|go:"GO:0042605"(peptide antigen binding)|ensembl:ENSG00000235657|ensembl:ENSP00000403575|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0005886"(plasma membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|interpro:IPR036179|interpro:IPR037055|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0006955"(immune response)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)	-	-	no-uniprot-update:	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:r6UnYO31dZgh/h+E2JiAhAmKj2Y9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:P01040	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O95232	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-395671|uniprotkb:Q6PHR9|uniprotkb:Q9NUY0|uniprotkb:Q9P2S7|uniprotkb:B3KN54|uniprotkb:D3DTY1|ensembl:ENSP00000240304|ensembl:ENSP00000425092	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:lc7l3_human(display_long)|uniprotkb:LUC7L3(gene name)|psi-mi:LUC7L3(display_short)|uniprotkb:cAMP regulatory element-associated protein 1(gene name synonym)|uniprotkb:Luc7A(gene name synonym)|uniprotkb:Okadaic acid-inducible phosphoprotein OA48-18(gene name synonym)|uniprotkb:CREAP1(gene name synonym)|uniprotkb:O48(gene name synonym)|uniprotkb:CROP(gene name synonym)|uniprotkb:Cisplatin resistance-associated-overexpressed protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006098.2|refseq:NP_057508.2|ensembl:ENSG00000108848(gene)|ensembl:ENST00000240304(transcript)|ensembl:ENST00000505658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:O95232	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:UywyrESxjWtcX7tXUEvhA6Dks709606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O75683	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O60506	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O43823	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1237481|ensembl:ENSP00000269701	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O43390	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O43159	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2008793|uniprotkb:Q7KZ78|uniprotkb:Q9BVM6|ensembl:ENSP00000254605	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:rrp8_human(display_long)|uniprotkb:RRP8(gene name)|psi-mi:RRP8(display_short)|uniprotkb:hucep-1(orf name)|uniprotkb:NML(gene name synonym)|uniprotkb:Nucleomethylin(gene name synonym)|uniprotkb:KIAA0409(gene name synonym)|uniprotkb:Cerebral protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_056139.1|dip:DIP-46686N|ensembl:ENSG00000132275(gene)|ensembl:ENST00000254605(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR007823(Methyltransferase-related)|interpro:IPR023576|interpro:IPR029063|interpro:IPR042036|mint:O43159|rcsb pdb:2ZFU|reactome:R-HSA-427359	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:SNRPocKaPjMCXSLDe1ytWlUWYTw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O15226	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:O00425	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:M0QZX5	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21261668|ensembl:ENSP00000470834	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:m0qzx5_human(display_long)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000105135(gene)|ensembl:ENST00000598709(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR029035	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:hXycrRCQFMdvAFb4dmK4T7Z6NM89606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:H0YIB4	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21259571|ensembl:ENSP00000449030	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:h0yib4_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000111786(gene)|ensembl:ENST00000550458(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:9BMC6MJa/41h6TqzB+1Bcm/MLvI9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q9NVI7-3	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-25339540|ensembl:ENSP00000439290	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:q9nvi7-3(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000197785(gene)|ensembl:ENST00000536055(transcript)|intact:EBI-352007(isoform-parent)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:fJvDRPIoHc84N+Kxf2shkOo1qB09606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:D6RD17	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21262381|ensembl:ENSP00000427112	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:d6rd17_human(display_long)|uniprotkb:JCHAIN(gene name)|psi-mi:JCHAIN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000132465(gene)|ensembl:ENST00000510614(transcript)|interpro:IPR024110	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:AViLVG4XxYpLehw4CUvO1qu+1009606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:B1AMU7	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21262369|ensembl:ENSP00000359921	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:b1amu7_human(display_long)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000171311(gene)|ensembl:ENST00000370884(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR039771	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:b9tr3sGjFCkR7UVUwyPn1ld9mNo9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:A0A0B4J210	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-21261608|ensembl:ENSP00000428589	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:a0a0b4j210_human(display_long)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262435|imex:IM-26691-127	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/01/09	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:JhmSJsGytpAfTKbzSVdqNiGzXBw9606	rigid:4o/DKaMxfVznmKI1V8cf4AGLN9k	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q969M3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2124787|uniprotkb:Q4VSN6|uniprotkb:Q53EX4|uniprotkb:Q8NHE5|uniprotkb:Q9H338|uniprotkb:Q9H3U4|uniprotkb:D3DQF5|ensembl:ENSP00000274496|ensembl:ENSP00000397704	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:yipf5_human(display_long)|uniprotkb:YIPF5(gene name)|psi-mi:YIPF5(display_short)|uniprotkb:FINGER5(gene name synonym)|uniprotkb:YIP1A(gene name synonym)|uniprotkb:YIP1 family member 5(gene name synonym)|uniprotkb:YPT-interacting protein 1 A(gene name synonym)|uniprotkb:Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 5(gene name synonym)|uniprotkb:PP12723(orf name)|uniprotkb:SB140(orf name)|uniprotkb:UNQ3123/PRO10275(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001020118.1|refseq:NP_110426.4|refseq:NP_001258661.1|ensembl:ENST00000274496(transcript)|ensembl:ENST00000448443(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070971"(endoplasmic reticulum exit site)|mint:Q969M3|ensembl:ENSG00000145817(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:tNd/CdASqK/08G9O9h3nivCTzKw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IXI1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BXS4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-7054441|ensembl:ENSP00000234831|uniprotkb:Q4VBP9|uniprotkb:O75393|intact:MINT-8201752|uniprotkb:Q96KX7|uniprotkb:Q5T705|uniprotkb:B3KQL7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmm59_human(display_long)|uniprotkb:TMEM59(gene name)|psi-mi:TMEM59(display_short)|uniprotkb:C1orf8(gene name synonym)|uniprotkb:Liver membrane-bound protein(gene name synonym)|uniprotkb:HSPC001(orf name)|uniprotkb:UNQ169/PRO195(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001291972.1|refseq:NP_001291978.1|refseq:NP_001291979.1|refseq:NP_001291980.1|refseq:NP_001291981.1|refseq:NP_001291995.1|ensembl:ENSG00000116209(gene)|ensembl:ENST00000234831(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090285"(negative regulation of protein glycosylation in Golgi)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR022065|mint:Q9BXS4|reactome:R-HSA-9013407|reactome:R-HSA-9696273|refseq:NP_004863.2	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yA2dq3FVXnxw9Peh6f3UBqGzFpM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8N3P4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-7261494|intact:MINT-1196904|uniprotkb:Q9BVP9|uniprotkb:Q63HP2|uniprotkb:C9JB61|uniprotkb:O94896|uniprotkb:Q9H9B0|uniprotkb:A8K8Q8|uniprotkb:B9EIQ1|ensembl:ENSP00000487164	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:vps8_human(display_long)|uniprotkb:VPS8(gene name)|psi-mi:VPS8(display_short)|uniprotkb:KIAA0804(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001009921.1|refseq:NP_056118.2|refseq:XP_005247308.1|ensembl:ENST00000625842(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0015031"(protein transport)|go:"GO:0033263"(CORVET complex)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025941|interpro:IPR036322|ensembl:ENSG00000156931(gene)	-	-	comment:mint|comment:homomint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:bV6Coru+kAusoFb1qAV6Z5Na9849606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:X5CMH5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262914|ensembl:ENSP00000393580|ensembl:ENSP00000406540|ensembl:ENSP00000416471	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:x5cmh5_human(display_long)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000223481(gene)|ensembl:ENSG00000225967(gene)|ensembl:ENSG00000232326(gene)|ensembl:ENST00000452371(transcript)|ensembl:ENST00000455842(transcript)|ensembl:ENST00000457634(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0042287"(MHC protein binding)|go:"GO:0042825"(TAP complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|refseq:NP_000535.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:c5RxmRf2D24+XCfzlzKnDvh80fM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:U3KQ84	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262903|ensembl:ENSP00000475634	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:u3kq84_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000244038(gene)|ensembl:ENST00000464364(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:NGgqak8QRgCkgA8i0YquXgL3f909606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y679	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y673	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11725055|uniprotkb:B4DR37|uniprotkb:Q5TBA6|ensembl:ENSP00000239891	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:alg5_human(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:Asparagine-linked glycosylation protein 5 homolog(gene name synonym)|uniprotkb:HSPC149(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001135836.1|refseq:NP_037470.1|ensembl:ENSG00000120697(gene)|ensembl:ENST00000239891(transcript)|go:"GO:0004576"(oligosaccharyl transferase activity)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-HSA-480985	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:BrOq249TNUXkpnFulYQvYILVHUA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5L4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5L0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5J9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y4W6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3U8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3F4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3E5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3D0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3C1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UPY3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UPN7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UL15	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UII2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UI26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UI12	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UI10	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UHI6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UGJ1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UFG5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-741214|intact:EBI-28979499|ensembl:ENSP00000397394|ensembl:ENSP00000466372|ensembl:ENSP00000467861|ensembl:ENSP00000468688|uniprotkb:Q8N9R7|uniprotkb:Q8WV94|uniprotkb:B3KQN6|intact:EBI-2561342	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cs025_human(display_long)|uniprotkb:C19orf25(gene name)|psi-mi:C19orf25(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_689695.2|ensembl:ENSG00000119559(gene)|ensembl:ENST00000436106(transcript)|ensembl:ENST00000585675(transcript)|ensembl:ENST00000586564(transcript)|ensembl:ENST00000592872(transcript)|interpro:IPR028227|ensembl:ENSP00000397394|ensembl:ENSP00000468688|ensembl:ENSP00000466372|ensembl:ENSP00000467861|refseq:XP_006722716.1|refseq:XP_005259563.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8x4kfH5+Et/gOjw93ulVXPlAync9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UBV2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UBQ5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UBF2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9P0I2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9P035	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NZ01	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYU2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYP7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11037623|uniprotkb:Q5TGH5|uniprotkb:F6SH78|uniprotkb:B4DZJ2|uniprotkb:Q59EL3|uniprotkb:Q8NCG4|uniprotkb:Q7L2S5|uniprotkb:Q9UI22|uniprotkb:Q6NXE7|ensembl:ENSP00000306640	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:elov5_human(display_long)|uniprotkb:Very long chain 3-ketoacyl-CoA synthase 5(gene name synonym)|uniprotkb:Very long chain 3-oxoacyl-CoA synthase 5(gene name synonym)|uniprotkb:PRO0530(orf name)|uniprotkb:ELOVL5(gene name)|psi-mi:ELOVL5(display_short)|uniprotkb:3-keto acyl-CoA synthase ELOVL5(gene name synonym)|uniprotkb:ELOVL fatty acid elongase 5(gene name synonym)|uniprotkb:ELOVL2(gene name synonym)|uniprotkb:Fatty acid elongase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001229757.1|refseq:NP_001229759.1|refseq:NP_001229760.1|refseq:NP_001288785.1|refseq:NP_068586.1|ensembl:ENSG00000012660(gene)|ensembl:ENST00000304434(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0016020"(membrane)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0097447"(dendritic tree)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR033677|reactome:R-HSA-2046105|reactome:R-HSA-2046106|reactome:R-HSA-75876	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7kQZS7mYa5eCSOslo4+z9nwtxxk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NXW2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NVI1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NU22	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NTJ5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NTJ3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NR50	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NP72	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9HAV4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H7F0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H4A6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H3U1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1048763|uniprotkb:Q7L3Y6|uniprotkb:Q9H3U8|uniprotkb:Q9NSE8|uniprotkb:Q9NSE9|uniprotkb:A8K6F7|ensembl:ENSP00000407487	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:un45a_human(display_long)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:SMAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001034764.1|refseq:NP_061141.2|refseq:XP_011520081.1|ensembl:ENSG00000140553(gene)|ensembl:ENST00000418476(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660|rcsb pdb:2DBA|refseq:NP_001310548.1|refseq:NP_001310550.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:P/N+VqGUtK2vWzHyKq6UzC4xxdo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H078	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9C0E2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BXW9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BVK6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BTV4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BSJ8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BSJ2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BRX2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BRK5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1389808|uniprotkb:Q8NBQ3|uniprotkb:Q9NZP7|uniprotkb:B1AME5|uniprotkb:B2RDF1|uniprotkb:B4DSM1|uniprotkb:Q53G52|uniprotkb:Q53HQ9|uniprotkb:Q96AA1|uniprotkb:Q9UN53|intact:EBI-2511482|uniprotkb:B1AME6	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cab45_human(display_long)|uniprotkb:Stromal cell-derived factor 4(gene name synonym)|uniprotkb:SDF4(gene name)|psi-mi:SDF4(display_short)|uniprotkb:CAB45(gene name synonym)|uniprotkb:PSEC0034(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057631.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_011539858.1|interpro:IPR027240|mint:Q9BRK5|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0021549"(cerebellum development)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070625"(zymogen granule exocytosis)|go:"GO:0099558"(maintenance of synapse structure)|refseq:NP_057260.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wQ0Ov1MDf6p0BmUCZRAS+Na/ERc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BQE3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99653	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99623	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99460	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99442	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-949221|ensembl:ENSP00000337688|ensembl:ENSP00000420331|uniprotkb:O00682|uniprotkb:O00729|intact:EBI-2689278|uniprotkb:D3DNQ0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sec62_human(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:TLOC1(gene name synonym)|uniprotkb:Translocation protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000008952(gene)|ensembl:ENST00000337002(transcript)|ensembl:ENST00000480708(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR004728(Translocation protein Sec62)|rcsb pdb:7BRT|refseq:NP_003253.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:u7na6TjTcixVS+ZK2ygkFA1QDKY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96R06	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96P70	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96KP1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|ensembl:ENSP00000230449|uniprotkb:B2RBE6	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000112685(gene)|ensembl:ENST00000230449(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|dip:DIP-31795N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96KC8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96KA5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96JJ7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96FW1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96ER3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96DZ1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96D53	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96CP6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1384139|uniprotkb:A6NKY7|uniprotkb:Q8NC77|uniprotkb:Q9P1Z5|ensembl:ENSP00000441032	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:astra_human(display_long)|uniprotkb:GRAMD1A(gene name)|psi-mi:GRAMD1A(display_short)|uniprotkb:KIAA1533(gene name synonym)|uniprotkb:GRAM domain-containing protein 1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001306964.1|refseq:NP_001129671.1|refseq:NP_065946.2|refseq:NP_001306963.1|refseq:NP_001306965.1|ensembl:ENSG00000089351(gene)|ensembl:ENST00000317991(transcript)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|mint:Q96CP6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:S7fzTVbf+LB0tpV7JvPZzpcs8709606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96CN4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96AG4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96A65	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96A33	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q969V3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056979|uniprotkb:O75252|uniprotkb:Q6FI60|uniprotkb:Q6ZMB7|uniprotkb:Q8TAT7|uniprotkb:Q96H48|uniprotkb:Q96IS7|uniprotkb:Q9BQH9|uniprotkb:Q9BTX4|uniprotkb:Q9NPP2|uniprotkb:D6W613|ensembl:ENSP00000246117	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ncln_human(display_long)|uniprotkb:NCLN(gene name)|psi-mi:NCLN(display_short)|uniprotkb:Nicastrin-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064555.2|refseq:NP_001308392.1|ensembl:ENSG00000125912(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR007484(Peptidase M28)|interpro:IPR016574(Nicalin)|mint:Q969V3|rcsb pdb:6W6L|ensembl:ENST00000246117(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:h2Md0pyypG6ZFLWOxHxQvJKFg/k9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q969N2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q93008	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q92973	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WXD5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WWC4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WVX9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WVM8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WUM0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEX9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEQ6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEM1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TCJ2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TCG1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TC07	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TAT6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1994109|uniprotkb:Q8N3J1|uniprotkb:Q9H8V2|uniprotkb:Q9H964|uniprotkb:Q9NWR5|uniprotkb:Q9P229|ensembl:ENSP00000331487	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:npl4_human(display_long)|uniprotkb:NPLOC4(gene name)|psi-mi:NPLOC4(display_short)|uniprotkb:KIAA1499(gene name synonym)|uniprotkb:NPL4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011523281.1|refseq:NP_060391.2|dip:DIP-44059N|ensembl:ENSG00000182446(gene)|ensembl:ENST00000331134(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036501"(UFD1-NPL4 complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR007716(NPL4, zinc-binding putative)|interpro:IPR007717(NPL4)|interpro:IPR016563(Polyubiquitin-tagged protein recognition complex, Npl4 component)|interpro:IPR024682|interpro:IPR029071|interpro:IPR036443|interpro:IPR037518|mint:Q8TAT6|reactome:R-HSA-110320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GXRNmG7yqEf5aFMo7yPDih93yfk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8NI27	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1755078|intact:EBI-2802903|uniprotkb:A6NM50|uniprotkb:Q9H8I6|uniprotkb:Q5JZ12|uniprotkb:Q6IN92|ensembl:ENSP00000245838|ensembl:ENSP00000347959	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:thoc2_human(display_long)|uniprotkb:hTREX120(gene name synonym)|uniprotkb:THOC2(gene name)|psi-mi:THOC2(display_short)|uniprotkb:CXorf3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001075019.1|ensembl:ENSG00000125676(gene)|ensembl:ENST00000245838(transcript)|ensembl:ENST00000355725(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048666"(neuron development)|go:"GO:0048699"(generation of neurons)|interpro:IPR021418|interpro:IPR021726|interpro:IPR032302|interpro:IPR040007|mint:Q8NI27|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GJCI/aEu/upu9s/gMVJvt56PXP89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8N766	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8N5G2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IXB1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IV08	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|ensembl:ENSP00000348901|ensembl:ENSP00000386293|ensembl:ENSP00000386938|ensembl:ENSP00000387022|ensembl:ENSP00000387050	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pld3_human(display_long)|uniprotkb:Choline phosphatase 3(gene name synonym)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D3(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001278240.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:NP_001026866.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|ensembl:ENSG00000105223(gene)|ensembl:ENST00000356508(transcript)|ensembl:ENST00000409281(transcript)|ensembl:ENST00000409419(transcript)|ensembl:ENST00000409587(transcript)|ensembl:ENST00000409735(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002376"(immune system process)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:XP_006723185.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q86VP6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q7L1Q6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6PML9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006336.3|ensembl:ENSG00000014824(gene)|ensembl:ENST00000264451(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|rcsb pdb:2ENK	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P4Q7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11918149|ensembl:ENSP00000366275|uniprotkb:B7Z1U0|uniprotkb:C7SQM3|uniprotkb:C7SQM4|uniprotkb:C7SQM5|uniprotkb:Q53RE5|uniprotkb:Q9H9G3|uniprotkb:Q9HCI0|uniprotkb:Q9NRN1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cnnm4_human(display_long)|uniprotkb:CNNM4(gene name)|psi-mi:CNNM4(display_short)|uniprotkb:ACDP4(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 4(gene name synonym)|uniprotkb:Cyclin-M4(gene name synonym)|uniprotkb:KIAA1592(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000158158(gene)|ensembl:ENST00000377075(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007601"(visual perception)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050896"(response to stimulus)|go:"GO:0055065"(metal ion homeostasis)|go:"GO:0070166"(enamel mineralization)|interpro:IPR000595(Cyclic nucleotide-binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030425"(dendrite)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR018490|interpro:IPR044751|rcsb pdb:6G52|rcsb pdb:6RS2|refseq:NP_064569.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sdYQzd8X3Gz9Okurljb9g+Homt89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P3X3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057046|uniprotkb:A6NKJ0|uniprotkb:Q96SS5|uniprotkb:Q9BVF1|uniprotkb:Q9NWR4|uniprotkb:Q9NXG4|ensembl:ENSP00000313953	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ttc27_human(display_long)|uniprotkb:TTC27(gene name)|psi-mi:TTC27(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001180438.1|refseq:NP_060205.3|ensembl:ENSG00000018699(gene)|ensembl:ENST00000317907(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR044244|mint:Q6P3X3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LvE8UTgFaNjAZEkxCnmPTr/YP+Q9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P1M0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6NUQ1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6IAX9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-9377198	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q6iax9_human(display_long)|uniprotkb:SRPR(gene name)|psi-mi:SRPR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	interpro:IPR042101|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:i5XIznACfXfJKLW2hBieI4jCrtg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5VYK3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-521451|uniprotkb:O15074|uniprotkb:Q8WU82|ensembl:ENSP00000339889	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_005251907.1|ensembl:ENSG00000136813(gene)|ensembl:ENST00000338205(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043248"(proteasome assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5VV42	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5TB53	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260364|ensembl:ENSP00000401152	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5tb53_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0016021"(integral component of membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensembl:ENSG00000077147(gene)|ensembl:ENST00000443638(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:T1DWVoePJSFkdgudFKdtzv/VaCg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5TAQ9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5T4S7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5T160	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050546|uniprotkb:Q96FU5|uniprotkb:Q9H8K8|uniprotkb:B2RDT7|ensembl:ENSP00000358549	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:syrm_human(display_long)|uniprotkb:RARS2(gene name)|psi-mi:RARS2(display_short)|uniprotkb:RARSL(gene name synonym)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064716.2|ensembl:ENSG00000146282(gene)|ensembl:ENST00000369536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q5T160|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jslLCkjYCriiVlR94nHAhNIYVeY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5SZE2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262890|ensembl:ENSP00000394012	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5sze2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143418(gene)|ensembl:ENST00000457392(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ka5Rf62LvM6VKgqeYwzYWklPFHc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5JYR7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262879|ensembl:ENSP00000362735	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5jyr7_human(display_long)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|ensembl:ENSG00000118705(gene)|ensembl:ENST00000373632(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XtgQttct6NCg4alvIHMvEzDw4Ak9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5JSD2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5H9R7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5BJH7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q53GQ0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q3MHD2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q29RF7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q16637	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q16576	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q16531	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15758	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15645	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15386	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15293	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15165	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3909798|ensembl:ENSP00000222572|ensembl:ENSP00000488838|uniprotkb:O15114|uniprotkb:B4DJD5|uniprotkb:Q5FBX7|uniprotkb:O15115|uniprotkb:B2RCP9|uniprotkb:Q86YL0|uniprotkb:O75856|uniprotkb:A4D1H7|intact:EBI-10966394	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pon2_human(display_long)|uniprotkb:PON2(gene name)|psi-mi:PON2(display_short)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000105854(gene)|ensembl:ENST00000222572(transcript)|ensembl:ENST00000633531(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009636"(response to toxic substance)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|mint:Q15165|reactome:R-HSA-2142688|refseq:NP_000296.2|dip:DIP-61136N|refseq:NP_001018171.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9zE87aut0R8eYxaXM+HgYsJxLYI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15084	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15043	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952|ensembl:ENSP00000370635	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011542780.1|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_016868783.1|refseq:XP_016868784.1|ensembl:ENSG00000104635(gene)|ensembl:ENST00000289952(transcript)|ensembl:ENST00000381237(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015296"("anion:cation symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033212"(iron import into cell)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055071"(manganese ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0098739"(import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|mint:Q15043|reactome:R-HSA-442380	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15021	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15008	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15006	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14974	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14573	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14318	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14257	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14165	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046466|ensembl:ENSP00000228506	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14152	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13501	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13438	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13404	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13200	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13144	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13015	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-6269719|ensembl:ENSP00000357917	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q12797	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q07065	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q00765	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q00577	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045860|ensembl:ENSP00000332706|ensembl:ENSP00000499133	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pura_human(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:PURA(gene name)|psi-mi:PURA(display_short)|uniprotkb:PUR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005850.1|ensembl:ENSG00000185129(gene)|ensembl:ENST00000331327(transcript)|ensembl:ENST00000651386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:Q00577	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4NuTKCFE1X+wdaAs+0Brd8IsFS89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q00325	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P83436	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P78347	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P63167	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62979	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62891	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62314	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62304	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62195	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62191	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P61981	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P60891	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P57678	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P56385	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P56381	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3904845|uniprotkb:E1P5H6|uniprotkb:B2RDD0|uniprotkb:Q53XU6|ensembl:ENSP00000243997|ensembl:ENSP00000379019|ensembl:ENSP00000379023	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5e_human(display_long)|uniprotkb:ATP5F1E(gene name)|psi-mi:ATP5F1E(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATP5E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_008817.1|ensembl:ENSG00000124172(gene)|ensembl:ENST00000243997(transcript)|ensembl:ENST00000395659(transcript)|ensembl:ENST00000395663(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:b8qOktspV0v7Gs9uQPpLHf6kLqI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P56192	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|uniprotkb:B3KVK7|ensembl:ENSP00000262027	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|reactome:R-HSA-379716|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|refseq:NP_004981.2|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000166986(gene)|ensembl:ENST00000262027(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|dip:DIP-38164N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55786	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55209	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55084	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55072	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55060	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P54709	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P53621	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P53618	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P52701	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P52429	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P52292	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P51665	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P51648	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P51571	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P51570	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P50402	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P48444	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P48047	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P46977	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P46060	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P43686	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P42695	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P42345	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40939	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40938	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1055010|intact:EBI-2512011|uniprotkb:O15252|intact:EBI-1169853|uniprotkb:Q5W0E8|uniprotkb:C9JU95|ensembl:ENSP00000369411	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rfc3_human(display_long)|uniprotkb:RFC3(gene name)|psi-mi:RFC3(display_short)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002906.1|refseq:NP_853536.2|ensembl:ENSG00000133119(gene)|ensembl:ENST00000380071(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0046683"(response to organophosphorus)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|mint:P40938|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-6804756|dip:DIP-36432N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XaK3OCno6yS3ubSiJhdBrW52VAw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40855	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P39880	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P36542	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P35998	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P35606	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P31946	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P31689	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P31040	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P30154	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P30101	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P29144	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044672|uniprotkb:Q5VZU8|ensembl:ENSP00000365233	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tpp2_human(display_long)|uniprotkb:Tripeptidyl-peptidase II(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:TPP2(gene name)|psi-mi:TPP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003282.2|ensembl:ENSG00000134900(gene)|ensembl:ENST00000376065(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022229|interpro:IPR022398|interpro:IPR023828|interpro:IPR034051|interpro:IPR036852|mint:P29144|reactome:R-HSA-983168|refseq:NP_001317517.1|dip:DIP-50761N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:I+B6XApXumvX26aR5AdMhkhZVc49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P28072	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P28070	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P27824	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P27797	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P25705	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P25205	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P24539	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P21912	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P20020	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P19388	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P18859	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P18031	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-968788|ensembl:ENSP00000360683|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000196396(gene)|ensembl:ENST00000371621(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097443"(sorting endosome)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1AAX|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2NT7|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2NTA|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2QBP|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2QBS|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2VEU|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2F6Z|rcsb pdb:2ZMM|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:6OMY|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:3EB1|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:7KEN|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MM1|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|rcsb pdb:6PFW|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QDV|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17980	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17931	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17302	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P16615	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P14625	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P13489	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P13073	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P12236	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P11310	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000007.1|refseq:NP_001120800.1|dip:DIP-34281N|ensembl:ENSG00000117054(gene)|ensembl:ENST00000370841(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P07919	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1224427|uniprotkb:Q5TDF6|uniprotkb:Q6LDB8|uniprotkb:Q9BQ91|uniprotkb:D3DQ18|uniprotkb:B2R4V9|ensembl:ENSP00000309565	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:qcr6_human(display_long)|uniprotkb:UQCRH(gene name)|psi-mi:UQCRH(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex 11 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 11 kDa protein(gene name synonym)|uniprotkb:Mitochondrial hinge protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005995.2|ensembl:ENSG00000173660(gene)|ensembl:ENST00000311672(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR003422(Ubiquinol-cytochrome C reductase hinge)|interpro:IPR023184|interpro:IPR036811|mint:P07919|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1f1RPTV/dS3CK24n/YSvDPXLm5c9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P06576	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05556	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05026	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05023	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P04843	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P03928	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:YP_003024030.1|ensembl:ENSG00000228253(gene)|ensembl:ENST00000361851(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P02786	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95793	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95470	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95394	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-9515816|uniprotkb:B2RB65|uniprotkb:B4DX94|uniprotkb:D6RF12|uniprotkb:E1P547|uniprotkb:E9PF86|uniprotkb:Q5JWR4|uniprotkb:Q96J46|uniprotkb:Q9H8G5|uniprotkb:Q9NS94|uniprotkb:Q9NTT6|uniprotkb:Q9UFV5|uniprotkb:Q9UIY2|ensembl:ENSP00000424874	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:agm1_human(display_long)|uniprotkb:PGM3(gene name)|psi-mi:PGM3(display_short)|uniprotkb:AGM1(gene name synonym)|uniprotkb:Acetylglucosamine phosphomutase(gene name synonym)|uniprotkb:N-acetylglucosamine-phosphate mutase(gene name synonym)|uniprotkb:Phosphoglucomutase-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_016866425.1|refseq:NP_001186846.1|refseq:NP_001186848.1|refseq:NP_056414.1|ensembl:ENSG00000013375(gene)|ensembl:ENST00000513973(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004610"(phosphoacetylglucosamine mutase activity)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0030097"(hemopoiesis)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR016657(Phosphoacetylglucosamine mutase)|interpro:IPR036900|mint:O95394|reactome:R-HSA-446210	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:W5By9C2GhzNKHCyrO1opg79FQ6I9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95373	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95347	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94905	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94874	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1048088|intact:EBI-2798769|uniprotkb:Q8N765|uniprotkb:Q9NTQ0|uniprotkb:A0PJ53|uniprotkb:B4DJ57|uniprotkb:C0H5X5|ensembl:ENSP00000358283	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ufl1_human(display_long)|uniprotkb:UFL1(gene name)|psi-mi:UFL1(display_short)|uniprotkb:E3 UFM1-protein transferase 1(gene name synonym)|uniprotkb:KIAA0776(gene name synonym)|uniprotkb:Novel LZAP-binding protein(gene name synonym)|uniprotkb:RCAD(gene name synonym)|uniprotkb:Regulator of C53/LZAP and DDRGK1(gene name synonym)|uniprotkb:NLBP(gene name synonym)|uniprotkb:MAXER(gene name synonym)|uniprotkb:Multiple alpha-helix protein located at ER(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056138.1|ensembl:ENSG00000014123(gene)|ensembl:ENST00000369278(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016570"(histone modification)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061666"(UFM1 ligase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR018611|mint:O94874|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wiJotyDNle7GoYzFkOif0TFNr2w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94829	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94822	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O76071	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75964	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75947	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75822	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75694	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75616	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-6393536|ensembl:ENSP00000254928|uniprotkb:B3KN21|uniprotkb:C9JEC6|uniprotkb:O75617|uniprotkb:Q8WUY4|uniprotkb:Q96LE2|uniprotkb:Q96TC0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:eral1_human(display_long)|uniprotkb:ERAL1(gene name)|psi-mi:ERAL1(display_short)|uniprotkb:HERA(gene name synonym)|uniprotkb:Conserved ERA-like GTPase(gene name synonym)|uniprotkb:ERA-W(gene name synonym)|uniprotkb:ERA-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000132591(gene)|ensembl:ENST00000254928(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005662(GTP-binding protein Era)|interpro:IPR006073(GTP1/OBG)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR027417|interpro:IPR030388|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_005693.1|refseq:NP_001304914.1|refseq:NP_001304915.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2usCrRc4/GbXG5Ft8GY61w+rGds9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75534	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75477	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75396	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75306	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60884	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60762	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60613	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1052797|uniprotkb:Q4GZG7|uniprotkb:Q8WU00|uniprotkb:Q9BS64|uniprotkb:Q9GZW0|uniprotkb:Q9NR01|ensembl:ENSP00000328729|uniprotkb:A0A0B4J1S4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sep15_human(display_long)|uniprotkb:SELENOF(gene name)|psi-mi:SELENOF(display_short)|uniprotkb:15 kDa selenoprotein(gene name synonym)|uniprotkb:SEP15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004252.2|refseq:NP_976086.1|mint:O60613|interpro:IPR039992|ensembl:ENSG00000183291(gene)|ensembl:ENST00000331835(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR014912(Sep15/SelM redox)|interpro:IPR036249|interpro:IPR038219	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:O+C59EK6dpYLDbHWrJT10RtGus89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43852	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43819	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43592	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43324	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43242	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43169	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15397	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15355	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15270	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15269	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15260	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15173	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14980	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14975	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14967	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14579	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00743	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00487	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00410	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00264	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00232	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00231	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00165	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I3L4P8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I1SRC5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262862	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i1src5_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016740"(transferase activity)|refseq:NP_203524.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:JDcLdwWWYYINEC9w5ixJ13LVCHs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:H0YIN8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262854|ensembl:ENSP00000449781	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:h0yin8_human(display_long)|uniprotkb:ANKRD13A(gene name)|psi-mi:ANKRD13A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000076513(gene)|ensembl:ENST00000547639(transcript)|go:"GO:0016020"(membrane)|interpro:IPR021832	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4MpnX/lh3esDOFKvYs3ow3Rs/jc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:F8VUA7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:F5H018	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262838|ensembl:ENSP00000444042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:f5h018_human(display_long)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000132341(gene)|ensembl:ENST00000535090(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0015031"(protein transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0005525"(GTP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:RkI4tk8Aq2MGDfs4/HIiHgWcOPY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:E9PF19	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-10969956|ensembl:ENSP00000413979	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:e9pf19_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000106638(gene)|ensembl:ENST00000432538(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ojeQr2CRmM8DQKuwoj39v7u8bZY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:E7ETY7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262824|ensembl:ENSP00000427466	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:e7ety7_human(display_long)|uniprotkb:GPX8(gene name)|psi-mi:GPX8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000164294(gene)|ensembl:ENST00000515370(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0006979"(response to oxidative stress)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013376(Glutathione peroxidase Gpx7, putative)|interpro:IPR029760|interpro:IPR036249|refseq:NP_001293126.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ZVretoM7bZZ1SgAiDo2zCtorQZc9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:E1NZA1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258417	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JW96	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258889|ensembl:ENSP00000393320	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9jw96_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000167085(gene)|ensembl:ENST00000419140(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:m+QS9IeeD5UlWLw8/X1LBNGUqMQ9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JU30	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262814|ensembl:ENSP00000419516	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ju30_human(display_long)|uniprotkb:ST7(gene name)|psi-mi:ST7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENST00000490039(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007311(ST7)|ensembl:ENSG00000004866(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Rm7BdWrtmoIXb94+d4CFmnlv43w9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JU26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JLW8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JI87	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258875|ensembl:ENSP00000390129	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ji87_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000213585(gene)|ensembl:ENST00000425992(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XQBT9gfVRbapMMX65dSqFGkk7p09606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JGV6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262803|ensembl:ENSP00000404298	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9jgv6_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000099901(gene)|ensembl:ENST00000423859(transcript)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qjeGKWvXwtiE7cqLu8wKiZ61Z8I9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J6N9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260344|ensembl:ENSP00000418390	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j6n9_human(display_long)|uniprotkb:UFD1(gene name)|psi-mi:UFD1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000070010(gene)|ensembl:ENST00000494054(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YU/1QUJAWyW8kHeChAhsIDH0U609606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J4M6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J470	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258863|ensembl:ENSP00000405237	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j470_human(display_long)|uniprotkb:NCAPH(gene name)|psi-mi:NCAPH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000121152(gene)|ensembl:ENST00000435975(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|interpro:IPR022816	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lQwu9inrN64YhVd4Bvtoc9WEAOw9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J2P2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262793|ensembl:ENSP00000410643	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j2p2_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000105993(gene)|ensembl:ENST00000441561(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PI3kVGcOb+bwk/QBRF7sQDXJvow9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B7ZM73	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260321	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B7ZAQ6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11288340|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:B4DLT3|uniprotkb:B4DXE7|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302|ensembl:ENSP00000319673	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gphra_human(display_long)|uniprotkb:GPR89A(gene name)|psi-mi:GPR89A(display_short)|uniprotkb:GPHRA(gene name synonym)|uniprotkb:GPR89(gene name synonym)|uniprotkb:Protein GPR89A(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM01(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 90(gene name synonym)|uniprotkb:SH120(gene name synonym)|uniprotkb:CGI-13(orf name)|uniprotkb:UNQ192/PRO218(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001091081.1|refseq:NP_001091082.2|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_005277459.1|refseq:XP_005277461.1|refseq:XP_006711440.1|refseq:XP_006711441.1|refseq:XP_006711555.1|refseq:XP_006711556.1|refseq:XP_011507912.1|refseq:XP_011507914.1|refseq:XP_011508210.1|refseq:XP_011508211.1|refseq:XP_016856937.1|ensembl:ENSG00000117262(gene)|ensembl:ENST00000313835(transcript)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051452"(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B4DJ66	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262784	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:b4dj66_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:hCG_37689(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0000502"(proteasome complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:biPjxPsOaUM79xLrZSIgfdxk/S49606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B2RWN5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258368	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:A8MXH2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262770|ensembl:ENSP00000382523|ensembl:ENSP00000487901	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:a8mxh2_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000399614(transcript)|ensembl:ENST00000634217(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:oqZISVLJYMBgTjnNm0Lolfl6lOs9606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:A0FGR8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21262943|imex:IM-26691-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:OxuLDcGHJ2l/zgNwTjMnkdspKZg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0J9	uniprotkb:P62879	intact:EBI-765907|uniprotkb:Q9H610|uniprotkb:Q9NP36|uniprotkb:Q9NTI3|ensembl:ENSP00000263549	intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503	psi-mi:par12_human(display_long)|uniprotkb:Zinc finger CCCH domain-containing protein 1(gene name synonym)|uniprotkb:PARP12(gene name)|psi-mi:PARP12(display_short)|uniprotkb:ZC3HDC1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 12(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 12(gene name synonym)	psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263845|imex:IM-26691-91	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_073587.1|ensembl:ENSG00000059378(gene)|ensembl:ENST00000263549(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|rcsb pdb:2PQF|rcsb pdb:6V3W	refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:JYAGjPHJuEyh/yQE9vTfNOwXgNo9606	rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606	rigid:7p2mdCbebgrUFL+6lDvPairWA2c	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H0J9	uniprotkb:O00764	intact:EBI-765907|uniprotkb:Q9H610|uniprotkb:Q9NP36|uniprotkb:Q9NTI3|ensembl:ENSP00000263549	intact:EBI-1053189|uniprotkb:Q7Z2Y0|uniprotkb:Q9BS02|ensembl:ENSP00000291565	psi-mi:par12_human(display_long)|uniprotkb:Zinc finger CCCH domain-containing protein 1(gene name synonym)|uniprotkb:PARP12(gene name)|psi-mi:PARP12(display_short)|uniprotkb:ZC3HDC1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 12(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 12(gene name synonym)	psi-mi:pdxk_human(display_long)|uniprotkb:Pyridoxine kinase(gene name synonym)|uniprotkb:PDXK(gene name)|psi-mi:PDXK(display_short)|uniprotkb:PKH(gene name synonym)|uniprotkb:PNK(gene name synonym)|uniprotkb:C21orf124(gene name synonym)|uniprotkb:C21orf97(gene name synonym)|uniprotkb:PRED79(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263845|imex:IM-26691-91	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_073587.1|ensembl:ENSG00000059378(gene)|ensembl:ENST00000263549(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|rcsb pdb:2PQF|rcsb pdb:6V3W	refseq:NP_003672.1|refseq:XP_011528062.1|refseq:XP_011528063.1|refseq:XP_005261256.1|ensembl:ENSG00000160209(gene)|ensembl:ENST00000291565(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008478"(pyridoxal kinase activity)|go:"GO:0009443"(pyridoxal 5'-phosphate salvage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004625("Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase")|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR029056|mint:O00764|rcsb pdb:2AJP|rcsb pdb:2F7K|rcsb pdb:2YXT|rcsb pdb:2YXU|rcsb pdb:3FHX|rcsb pdb:3FHY|rcsb pdb:3KEU|rcsb pdb:4EN4|rcsb pdb:4EOH|reactome:R-HSA-6798695|reactome:R-HSA-964975|refseq:XP_016883972.1|refseq:XP_016883973.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:JYAGjPHJuEyh/yQE9vTfNOwXgNo9606	rogid:p1/Ff2UVhvPINiH9HGQsApv5M2Q9606	rigid:7p2mdCbebgrUFL+6lDvPairWA2c	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16875	uniprotkb:Q9UL15	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|uniprotkb:Q5VX15|ensembl:ENSP00000369100	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263857|imex:IM-26691-111	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004557.1|refseq:NP_001269559.1|refseq:NP_001300992.1|dip:DIP-33964N|ensembl:ENSG00000170525(gene)|ensembl:ENST00000379775(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0007420"(brain development)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|interpro:IPR013079(6-phosphofructo-2-kinase)	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:wmCJYC96bSdP0j/SjPSjGUY0hAw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16875	uniprotkb:K7EIH8	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|uniprotkb:Q5VX15|ensembl:ENSP00000369100	intact:EBI-21259594|ensembl:ENSP00000464756	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:k7eih8_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263857|imex:IM-26691-111	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004557.1|refseq:NP_001269559.1|refseq:NP_001300992.1|dip:DIP-33964N|ensembl:ENSG00000170525(gene)|ensembl:ENST00000379775(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0007420"(brain development)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|interpro:IPR013079(6-phosphofructo-2-kinase)	ensembl:ENSG00000168259(gene)|ensembl:ENST00000590348(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2020/10/22	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rogid:/fSmMnrnj/XjslVdpKlrM2w3nqA9606	rigid:wmCJYC96bSdP0j/SjPSjGUY0hAw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:Q99832	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P78371	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P50991	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P50990	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P49368	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P48643	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P40227	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:P17987	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8TCG2	uniprotkb:H0Y8H0	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864	intact:EBI-21263869|ensembl:ENSP00000421026	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:h0y8h0_human(display_long)|uniprotkb:DDX60L(gene name)|psi-mi:DDX60L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263881|imex:IM-26691-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060793.2|ensembl:ENSG00000038210(gene)|ensembl:ENST00000264864(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0016020"(membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516	go:"GO:0003676"(nucleic acid binding)|ensembl:ENSG00000181381(gene)|ensembl:ENST00000505863(transcript)|go:"GO:0005524"(ATP binding)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:c76HoovU2ZqbWWS2BJuAp+7IgSo9606	rigid:J2WbrqdPL8oEi74VNvh4sILdTgI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12796	uniprotkb:Q9NPI6	intact:EBI-2827376|uniprotkb:Q5T7J6|uniprotkb:B2R6Q0|ensembl:ENSP00000336931|uniprotkb:E1P515|uniprotkb:Q7Z5N0	intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8	psi-mi:pnrc1_human(display_long)|uniprotkb:PROL2(gene name synonym)|uniprotkb:Proline-rich protein 2(gene name synonym)|uniprotkb:Protein B4-2(gene name synonym)|uniprotkb:PNRC1(gene name)|psi-mi:PNRC1(display_short)	psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263914|imex:IM-26691-113	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006804.1|ensembl:ENSG00000146278(gene)|go:"GO:0005634"(nucleus)|interpro:IPR026780|mint:Q12796|ensembl:ENST00000336032(transcript)	ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:UltK56rTgcGIPUzX8WvV66EBD0U9606	rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606	rigid:a5qPEQOzlTBHrK1RDrn80pUnsW8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q12796	uniprotkb:Q6P2E9	intact:EBI-2827376|uniprotkb:Q5T7J6|uniprotkb:B2R6Q0|ensembl:ENSP00000336931|uniprotkb:E1P515|uniprotkb:Q7Z5N0	intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811	psi-mi:pnrc1_human(display_long)|uniprotkb:PROL2(gene name synonym)|uniprotkb:Proline-rich protein 2(gene name synonym)|uniprotkb:Protein B4-2(gene name synonym)|uniprotkb:PNRC1(gene name)|psi-mi:PNRC1(display_short)	psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263914|imex:IM-26691-113	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006804.1|ensembl:ENSG00000146278(gene)|go:"GO:0005634"(nucleus)|interpro:IPR026780|mint:Q12796|ensembl:ENST00000336032(transcript)	ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:UltK56rTgcGIPUzX8WvV66EBD0U9606	rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606	rigid:a5qPEQOzlTBHrK1RDrn80pUnsW8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q9Y244	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q9UN86	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q9UL46	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802|ensembl:ENSP00000495790	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002809.2|ensembl:ENSG00000100911(gene)|ensembl:ENSG00000284889(gene)|ensembl:ENST00000216802(transcript)|ensembl:ENST00000645325(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-5678895|reactome:R-HSA-174178|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8950505|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q9BT73	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-3921395|uniprotkb:A8MPW2|uniprotkb:A4D216|ensembl:ENSP00000252329|ensembl:ENSP00000288607|ensembl:ENSP00000384799	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psmg3_human(display_long)|uniprotkb:PSMG3(gene name)|psi-mi:PSMG3(display_short)|uniprotkb:C7orf48(gene name synonym)|uniprotkb:PAC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001127812.1|refseq:NP_115678.1|ensembl:ENSG00000157778(gene)|ensembl:ENST00000252329(transcript)|ensembl:ENST00000288607(transcript)|ensembl:ENST00000404674(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR018788|rcsb pdb:2Z5E|rcsb pdb:6JPT	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:CrIYLZ4iBSvXrENjAX2GHKhZJGI9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q99436	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:w880QftOor3RdaGvhCup7apz2OM9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q969U7	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-723276|uniprotkb:Q6IAH4|ensembl:ENSP00000325919|uniprotkb:B0YJB3|uniprotkb:Q9NRV1|uniprotkb:V9GYH7	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psmg2_human(display_long)|uniprotkb:TNFSF5IP1(gene name synonym)|uniprotkb:Tumor necrosis factor superfamily member 5-induced protein 1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-susceptibility protein 3(gene name synonym)|uniprotkb:PSMG2(gene name)|psi-mi:PSMG2(display_short)|uniprotkb:HCCA3(gene name synonym)|uniprotkb:PAC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_064617.2|refseq:NP_671692.1|ensembl:ENSG00000128789(gene)|ensembl:ENST00000317615(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0101031"(chaperone complex)|interpro:IPR016562(Uncharacterised conserved protein UCP010044)|interpro:IPR019151|interpro:IPR038389|mint:Q969U7|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:SPAm0zvvlstirkXJ1bydzEXduOI9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q5TCU3	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-21260047|ensembl:ENSP00000367541	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:q5tcu3_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|ensembl:ENSG00000198467(gene)|ensembl:ENST00000329305(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|refseq:NP_001288155.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:kX9YiC30bV5utZmy/Goq1V6H6SU9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q14978	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q13190	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:Q06323	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-712149|uniprotkb:H0YNE3|ensembl:ENSP00000206451|ensembl:ENSP00000495095|uniprotkb:Q9UEF4|uniprotkb:Q6IBM2|uniprotkb:A6NJG9	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psme1_human(display_long)|uniprotkb:Proteasome activator 28 subunit alpha(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 1(gene name synonym)|uniprotkb:11S regulator complex subunit alpha(gene name synonym)|uniprotkb:Interferon gamma up-regulated I-5111 protein(gene name synonym)|uniprotkb:PSME1(gene name)|psi-mi:PSME1(display_short)|uniprotkb:IFI5111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	reactome:R-HSA-5678895|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-5687128|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|ensembl:ENSG00000092010(gene)|ensembl:ENSG00000284916(gene)|ensembl:ENST00000206451(transcript)|ensembl:ENST00000645537(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0019884"(antigen processing and presentation of exogenous antigen)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q06323|rcsb pdb:1AVO|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|refseq:NP_006254.1|refseq:NP_001268457.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:kyTjI3VP2S7Bvwq4R0pJudnlOC09606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P62195	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P61289	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P60900	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P51665	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P49721	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P49720	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P28074	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:73T59wniLri/465F3BhBvwL1/LM9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P28066	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P25788	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P25787	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P25786	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P20618	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:DfIS480BUnqbXus9/KoojdkWgw09606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:P04049	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:O95456	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-6286129|ensembl:ENSP00000329915|uniprotkb:B5BUN2|uniprotkb:Q6FHA3|uniprotkb:Q6FHD3|uniprotkb:Q6S713	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psmg1_human(display_long)|uniprotkb:PSMG1(gene name)|psi-mi:PSMG1(display_short)|uniprotkb:C21LRP(gene name synonym)|uniprotkb:DSCR2(gene name synonym)|uniprotkb:PAC1(gene name synonym)|uniprotkb:Chromosome 21 leucine-rich protein(gene name synonym)|uniprotkb:Down syndrome critical region protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	ensembl:ENSG00000183527(gene)|ensembl:ENST00000331573(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0080129"(proteasome core complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR016565(Proteasome assembling chaperone-1)|refseq:NP_003711.1|refseq:NP_982257.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:8E77YMNgL+yxUkb8USuMUuO4RR49606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:O14818	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:H0YMZ1	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-21263926|ensembl:ENSP00000453802	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:h0ymz1_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	ensembl:ENSG00000041357(gene)|ensembl:ENST00000559365(transcript)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:4KUBk5o1UZudN8jLVrn5GI5rIqo9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P28065	uniprotkb:B1AKQ8	intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027	intact:EBI-6190833|ensembl:ENSP00000416651	psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym)	psi-mi:b1akq8_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21263945|imex:IM-26691-185	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	ensembl:ENSG00000078369(gene)|ensembl:ENST00000437146(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR036322	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606	rogid:BUB/7mf+WlDyk4rDXHXUrW9rKWE9606	rigid:MWFHyqlMvKaJRRJBGwP2Z2FFa34	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q6P2Q9	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:I0ot8b3pvieXRI66omFm145sGVA9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P53999	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-998260|uniprotkb:Q96L29|ensembl:ENSP00000265073|ensembl:ENSP00000422078|ensembl:ENSP00000422806|ensembl:ENSP00000426850|ensembl:ENSP00000427100	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:tcp4_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short)|uniprotkb:PC4(gene name synonym)|uniprotkb:RPO2TC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:XP_011512246.1|ensembl:ENSG00000113387(gene)|ensembl:ENST00000265073(transcript)|ensembl:ENST00000502897(transcript)|ensembl:ENST00000506237(transcript)|ensembl:ENST00000512913(transcript)|ensembl:ENST00000515355(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P53999|rcsb pdb:1PCF|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:2C62|rcsb pdb:2PHE|rcsb pdb:4USG|go:"GO:0003697"(single-stranded DNA binding)|rcsb pdb:6YCS|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|refseq:NP_006704.3|refseq:XP_016864475.1|refseq:XP_016864476.1|dip:DIP-29044N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:FqBKBuLmQS+idbd68EdKsTCzPg89606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P35249	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q9UKD2	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q9NYU2	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q9BPX5	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-711189|ensembl:ENSP00000259477|ensembl:ENSP00000345361|uniprotkb:Q7Z523	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:arp5l_human(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:ARPC5L(gene name)|psi-mi:ARPC5L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_112240.1|ensembl:ENSG00000136950(gene)|ensembl:ENST00000259477(transcript)|ensembl:ENST00000353214(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9BPX5|rcsb pdb:6YW6|dip:DIP-50399N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:JVproBu8rIrnlk39yXPC+ZrvoOk9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q99459	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q96H55	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-10983249|uniprotkb:Q59GS4|uniprotkb:Q9H5X2|ensembl:ENSP00000479518|ensembl:ENSP00000480242	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:myo19_human(display_long)|uniprotkb:MYO19(gene name)|psi-mi:MYO19(display_short)|uniprotkb:MYOHD1(gene name synonym)|uniprotkb:Myosin head domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001028752.1|refseq:NP_001157207.1|refseq:NP_079385.2|ensembl:ENSG00000278259(gene)|ensembl:ENSG00000278372(gene)|ensembl:ENST00000614623(transcript)|ensembl:ENST00000618519(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0051015"(actin filament binding)|go:"GO:0060002"(plus-end directed microfilament motor activity)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR036035|interpro:IPR036961|mint:Q96H55|reactome:R-HSA-9013419|reactome:R-HSA-9013425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:coJYx89cip3wKcsCF65cbMPBt7Y9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q53GS9	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1044822|uniprotkb:Q6NX47|uniprotkb:Q96RK9|uniprotkb:Q9BV89|uniprotkb:Q9H381|uniprotkb:Q9P050|uniprotkb:Q9Y310|uniprotkb:A8K086|ensembl:ENSP00000312981|ensembl:ENSP00000386864|uniprotkb:D6W5L4|intact:EBI-2557627|uniprotkb:B4DHT4|uniprotkb:B3KM40|uniprotkb:G5E9H0	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:snut2_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 65 kDa protein(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 39(gene name synonym)|uniprotkb:SAD1 homolog(gene name synonym)|uniprotkb:USP39(gene name)|psi-mi:USP39(display_short)|uniprotkb:CGI-21(orf name)|uniprotkb:HSPC332(orf name)|uniprotkb:PRO2855(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_006581.2|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051301"(cell division)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028889|interpro:IPR033809|interpro:IPR038765|go:"GO:0007049"(cell cycle)|rcsb pdb:3JCR|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000168883(gene)|ensembl:ENST00000323701(transcript)|ensembl:ENST00000409470(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|refseq:NP_001243656.1|refseq:NP_001243657.1|refseq:NP_001243654.1|refseq:NP_001243655.1|refseq:XP_006711985.1|refseq:XP_006711986.1|refseq:XP_011530789.1|refseq:XP_011530790.1|refseq:XP_016858671.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:AMLhskNenuv+zqXSa7VesSbbVK89606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q16637	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:Q15046	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P78347	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P62318	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P62314	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P53618	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P42285	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P09493	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P07947	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|intact:EBI-28995389|ensembl:ENSP00000324740|ensembl:ENSP00000462468	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSP00000324740|ensembl:ENSP00000462468|dip:DIP-33849N|ensembl:ENSG00000176105(gene)|ensembl:ENST00000314574(transcript)|ensembl:ENST00000584307(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:P05386	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O95905	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O75694	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O75643	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O15355	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O00425	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O00303	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:O00151	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	refseq:NP_066272.1|go:"GO:0003779"(actin binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031941"(filamentous actin)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensembl:ENSG00000107438(gene)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|rcsb pdb:1X62|rcsb pdb:2PKT|ensembl:ENST00000329399(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001725"(stress fiber)|go:"GO:0003713"(transcription coactivator activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:H3BND3	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-21261036|ensembl:ENSP00000454790	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:h3bnd3_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000167005(gene)|ensembl:ENST00000566340(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016787"(hydrolase activity)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:TI5fDynBieuRJX3FZfqTTPCUwI09606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:H0YCQ8	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-21258927|ensembl:ENSP00000432139	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:h0ycq8_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000149100(gene)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040750|ensembl:ENST00000526267(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:YKZM4oKZZ19CTTf2uGNjPgZ3eUQ9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:H0Y4X3	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-21264049|ensembl:ENSP00000394824	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:h0y4x3_human(display_long)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENST00000448303(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|ensembl:ENSG00000131051(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:PDU/f9VMtSAkJWflNnwpctULYUM9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:F8VUA7	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:D3DTH7	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-14404730	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:d3dth7_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:hCG_28722(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036961	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:itPzNzrab9uJCfAjy/xZdQTXH6M9606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51159	uniprotkb:C9IYT0	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761|ensembl:ENSP00000379601|ensembl:ENSP00000455012|ensembl:ENSP00000456059	intact:EBI-21264032|ensembl:ENSP00000400542	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:c9iyt0_human(display_long)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264064|imex:IM-26691-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|refseq:XP_005254633.1|ensembl:ENST00000396307(transcript)|ensembl:ENST00000564609(transcript)|ensembl:ENST00000569493(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006887"(exocytosis)|go:"GO:0007596"(blood coagulation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036257"(multivesicular body organization)|go:"GO:0042470"(melanosome)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903435"(positive regulation of constitutive secretory pathway)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|mint:P51159|rcsb pdb:6HUF|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000069974(gene)|ensembl:ENST00000336787(transcript)|dip:DIP-44244N	ensembl:ENSG00000130826(gene)|ensembl:ENST00000413910(transcript)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR020103|interpro:IPR036974	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:JostiuQXQJjW7Ba14Z/GNsPFP089606	rigid:tv4Hzm3VEt89W3ocVtIR4V8QyTU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q9NYZ3	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-2511327|intact:EBI-28974182|ensembl:ENSP00000415430|uniprotkb:Q9BRE0|uniprotkb:Q53GX5|uniprotkb:Q20WK2|uniprotkb:Q9UGZ9|uniprotkb:Q6DHX4|uniprotkb:Q5R3I6|uniprotkb:Q9Y557|uniprotkb:B0QYM3	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:gtse1_human(display_long)|uniprotkb:GTSE1(gene name)|psi-mi:GTSE1(display_short)|uniprotkb:Protein B99 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSG00000075218(gene)|ensembl:ENST00000454366(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|interpro:IPR026657|interpro:IPR026659|interpro:IPR032768|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-69481|reactome:R-HSA-8852276|ensembl:ENSP00000415430|refseq:NP_057510.4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:3vSRRbx11yGNbuaniX7ZtqE/cLI9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q9H932	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-21259418	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:q9h932_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	interpro:IPR031248|go:"GO:0004842"(ubiquitin-protein transferase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:0mNCLIEdl9i59B3dI4PljvgqNpA9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q9BZF9	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q8IVF2	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-3956940|uniprotkb:Q5BKX7|uniprotkb:Q7Z343|uniprotkb:Q7Z358|uniprotkb:Q7Z394|uniprotkb:Q7Z3G0|uniprotkb:Q86WQ6|uniprotkb:Q8IYY1|uniprotkb:Q8N3G4|uniprotkb:Q96EX9|ensembl:ENSP00000353114	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:ahnk2_human(display_long)|uniprotkb:AHNAK2(gene name)|psi-mi:AHNAK2(display_short)|uniprotkb:C14orf78(gene name synonym)|uniprotkb:KIAA2019(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSP00000353114|ensembl:ENST00000557457|ensembl:ENSP00000450998|refseq:NP_612429.2|ensembl:ENSG00000185567(gene)|ensembl:ENST00000333244(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR001478(PDZ/DHR/GLGF)|rcsb pdb:4CN0|interpro:IPR036034|refseq:XP_005267356.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:LvUoo/LEjXD8R3FiPvw9IlGyNdA9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q86YQ8	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-1642325|uniprotkb:Q2TB41|uniprotkb:Q86VY2|intact:EBI-2835651|ensembl:ENSP00000329748	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:cpne8_human(display_long)|uniprotkb:CPNE8(gene name)|psi-mi:CPNE8(display_short)|uniprotkb:Copine VIII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_705898.1|ensembl:ENSG00000139117(gene)|ensembl:ENST00000331366(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|reactome:R-HSA-9013148|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|refseq:XP_016874340.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:xTDQ9oRlt7RUyxsTJiRfMjVdbkI9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q6IAX9	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-9377198	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:q6iax9_human(display_long)|uniprotkb:SRPR(gene name)|psi-mi:SRPR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	interpro:IPR042101|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:i5XIznACfXfJKLW2hBieI4jCrtg9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q5TCU3	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-21260047|ensembl:ENSP00000367541	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:q5tcu3_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|ensembl:ENSG00000198467(gene)|ensembl:ENST00000329305(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|refseq:NP_001288155.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:kX9YiC30bV5utZmy/Goq1V6H6SU9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q15370	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q14978	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:Q14160	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:P62316	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:P53814	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-1199956|intact:EBI-1199983|uniprotkb:Q8N4H8|uniprotkb:Q8WWW1|uniprotkb:Q8WWW2|uniprotkb:O00569|uniprotkb:O95769|uniprotkb:O95937|uniprotkb:Q9P1S8|uniprotkb:Q9UIT1|uniprotkb:Q9UIT2|ensembl:ENSP00000328635	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:smtn_human(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSG00000183963(gene)|ensembl:ENST00000347557(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:P53814|rcsb pdb:2D87|refseq:NP_001193946.1|refseq:NP_001193947.1|refseq:NP_008863.3|refseq:NP_599031.1|refseq:NP_599032.2|ensembl:ENST00000333137|ensembl:ENSP00000329532|ensembl:ENSP00000328635|ensembl:ENST00000358743|ensembl:ENSP00000351593	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:na+f9ZixP42TZZ0uD5P5tzaroFA9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:P25398	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:P02545	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:O14579	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:O00469	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q63HN8	uniprotkb:B1AKQ8	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	intact:EBI-6190833|ensembl:ENSP00000416651	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:b1akq8_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264166|imex:IM-26691-115	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	ensembl:ENSG00000078369(gene)|ensembl:ENST00000437146(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR036322	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	rogid:BUB/7mf+WlDyk4rDXHXUrW9rKWE9606	rigid:8oiTzrU5sN5BU7++sj2Y4yzZGmc	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3I0	uniprotkb:Q9Y224	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	intact:EBI-1104547|ensembl:ENSP00000261700	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264222|imex:IM-26691-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rigid:i/UKlZ3krk1y5n/3i6VSeIXMED0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3I0	uniprotkb:Q92499	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264222|imex:IM-26691-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	rigid:i/UKlZ3krk1y5n/3i6VSeIXMED0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3I0	uniprotkb:Q52LJ0	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	intact:EBI-1043130|uniprotkb:Q8N935|ensembl:ENSP00000380734|uniprotkb:A8MUW5	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:fa98b_human(display_long)|uniprotkb:FAM98B(gene name)|psi-mi:FAM98B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264222|imex:IM-26691-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR018797|reactome:R-HSA-6784531|ensembl:ENSG00000171262(gene)|ensembl:ENST00000397609(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_775882.2|dip:DIP-50585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rogid:gi2tyKR3C5LWwtGV+7NzzsNETII9606	rigid:i/UKlZ3krk1y5n/3i6VSeIXMED0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3I0	uniprotkb:O95478	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	intact:EBI-2852366|ensembl:ENSP00000483484	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264222|imex:IM-26691-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606	rigid:i/UKlZ3krk1y5n/3i6VSeIXMED0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:Q9Y3I0	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:Q9UPQ0	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|ensembl:ENSG00000064042(gene)|ensembl:ENST00000313860(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029980|interpro:IPR031865|interpro:IPR036872|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:Q14677	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	ensembl:ENSP00000388340|ensembl:ENST00000523094|ensembl:ENSP00000429345|ensembl:ENST00000523908|ensembl:ENSP00000429824|ensembl:ENST00000530742|ensembl:ENSP00000433419|refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|ensembl:ENSG00000113282(gene)|ensembl:ENST00000411809(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722|dip:DIP-45604N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:Q04917	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P80723	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P63104	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P62273	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P61981	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P31946	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:G3V2R1	uniprotkb:P27348	intact:EBI-21264240|ensembl:ENSP00000450808|ensembl:ENSP00000486821	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:g3v2r1_human(display_long)|uniprotkb:SAMD4A(gene name)|psi-mi:SAMD4A(display_short)|uniprotkb:hCG_2028314(orf name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264254|imex:IM-26691-187	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000631086(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0030371"(translation repressor activity)|interpro:IPR037093|ensembl:ENSG00000020577(gene)|ensembl:ENST00000555192(transcript)|refseq:NP_001155049.1	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:feA1PuI6fNExCKMbkc1vVu4HYd49606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:1a18wS9ybLWxFmc5ZDEjqyIHkRQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3Z3	uniprotkb:Q8NBN7	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-3922765|uniprotkb:Q96G88|uniprotkb:Q6UX79|ensembl:ENSP00000391121|ensembl:ENSP00000477512	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:rdh13_human(display_long)|uniprotkb:RDH13(gene name)|psi-mi:RDH13(display_short)|uniprotkb:SDR7C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 3(gene name synonym)|uniprotkb:PSEC0082(orf name)|uniprotkb:UNQ736/PRO1430(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264312|imex:IM-26691-167	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	refseq:XP_011524709.1|refseq:NP_001139443.1|refseq:NP_612421.1|ensembl:ENSG00000160439(gene)|ensembl:ENST00000615256(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0009644"(response to high light intensity)|go:"GO:0010842"(retina layer formation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8NBN7|reactome:R-HSA-5365859|ensembl:ENSG00000276684(gene)|ensembl:ENST00000415061(transcript)|refseq:XP_005258530.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:UHfrKddjwiPXJ6xohB99Ua0jGZo9606	rigid:TAQS7emYjXhKXDQdFBudmd+LR5w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3Z3	uniprotkb:Q13438	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264312|imex:IM-26691-167	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:TAQS7emYjXhKXDQdFBudmd+LR5w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3Z3	uniprotkb:Q08380	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264312|imex:IM-26691-167	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:TAQS7emYjXhKXDQdFBudmd+LR5w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y3Z3	uniprotkb:F5H6I0	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-21264290|ensembl:ENSP00000437604|ensembl:ENSP00000483449	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:f5h6i0_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264312|imex:IM-26691-167	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000544417(transcript)|ensembl:ENST00000619603(transcript)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005576"(extracellular region)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0042612"(MHC class I protein complex)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:ozz8O8qq5JYH/2PskDG++k6NMVc9606	rigid:TAQS7emYjXhKXDQdFBudmd+LR5w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9BUQ8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-540096|uniprotkb:B2R600|uniprotkb:O43188|uniprotkb:B4DH15|intact:EBI-2557638|ensembl:ENSP00000310723	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ddx23_human(display_long)|uniprotkb:DEAD box protein 23(gene name synonym)|uniprotkb:100 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:U5-100kD(gene name synonym)|uniprotkb:PRP28 homolog(gene name synonym)|uniprotkb:DDX23(gene name)|psi-mi:DDX23(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_004809.2|ensembl:ENSG00000174243(gene)|ensembl:ENST00000308025(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9BUQ8|rcsb pdb:3JCR|rcsb pdb:4NHO|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-34974N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:tEDp48akFaCjRBBXB4jtyrAsLQ89606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q92878	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q6P2Q9	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350|ensembl:ENSP00000460348|ensembl:ENSP00000479194|ensembl:ENSP00000488611	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006436.3|ensembl:ENSG00000174231(gene)|ensembl:ENSG00000274442(gene)|ensembl:ENST00000304992(transcript)|ensembl:ENST00000572621(transcript)|ensembl:ENST00000614672(transcript)|ensembl:ENST00000634039(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5XJC|dip:DIP-29614N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:I0ot8b3pvieXRI66omFm145sGVA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q6P4F7	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-7543265|ensembl:ENSP00000355090|ensembl:ENSP00000479117|uniprotkb:B4DZN9|uniprotkb:Q9Y3S6|uniprotkb:Q6PI96|intact:MINT-3974818	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rhgba_human(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000275568(gene)|ensembl:ENSG00000198826(gene)|refseq:NP_001273408.1|refseq:NP_001273409.1|ensembl:ENST00000361627(transcript)|ensembl:ENST00000619401(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|mint:Q6P4F7|rcsb pdb:3EAP|reactome:R-HSA-8980692|refseq:NP_955389.1|refseq:NP_055598.1|ensembl:ENSP00000355090|ensembl:ENST00000543522|ensembl:ENSP00000440073|ensembl:ENST00000565905|ensembl:ENST00000567348|ensembl:ENSP00000454575|ensembl:ENST00000611363|ensembl:ENSP00000480085|ensembl:ENSP00000479117|ensembl:ENST00000622253|ensembl:ENSP00000481011|ensembl:ENSP00000455754	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75431	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|ensembl:ENSP00000249442|uniprotkb:Q8IZ68	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_001006636.1|refseq:NP_006545.1|ensembl:ENSG00000128654(gene)|ensembl:ENST00000249442(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)	-	-	comment:mint|function:Involved in transport of proteins into the mitochondrion	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:E9PRG8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-11324775|ensembl:ENSP00000432523|intact:EBI-21262272|uniprotkb:A0A0B4J220	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ck098_human(display_long)|uniprotkb:C11orf98(gene name)|psi-mi:C11orf98(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001273015.1|ensembl:ENSG00000278615(gene)|ensembl:ENST00000524958(transcript)|interpro:IPR037691|mint:E9PRG8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:VfLIp/LTQj4cvxS0emale/+FWJU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y617	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-709652|uniprotkb:Q96AW2|uniprotkb:Q9BQ12|intact:EBI-1046968|uniprotkb:Q5T7G6|uniprotkb:Q5T7G5|ensembl:ENSP00000365773	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:serc_human(display_long)|uniprotkb:Phosphohydroxythreonine aminotransferase(gene name synonym)|uniprotkb:PSAT1(gene name)|psi-mi:PSAT1(display_short)|uniprotkb:PSA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_066977.1|refseq:NP_478059.1|ensembl:ENSG00000135069(gene)|ensembl:ENST00000376588(transcript)|go:"GO:0004648"("O-phospho-L-serine:2-oxoglutarate aminotransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022278|rcsb pdb:3E77|reactome:R-HSA-977347	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:1gVfizgYpwzJZsqcNgNOfVfk4Dg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y512	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-748409|uniprotkb:Q969Y9|uniprotkb:Q96I46|uniprotkb:Q9NW85|uniprotkb:Q9UQM9|ensembl:ENSP00000345445|uniprotkb:Q53HC4|uniprotkb:Q56VW7	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sam50_human(display_long)|uniprotkb:SAMM50(gene name)|psi-mi:SAMM50(display_short)|uniprotkb:CGI-51(orf name)|uniprotkb:Transformation-related gene 3 protein(gene name synonym)|uniprotkb:TRG3(orf name)|uniprotkb:SAM50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000100347(gene)|refseq:NP_056195.3|ensembl:ENST00000350028(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q9Y512|rcsb pdb:6YOO|rcsb pdb:6YOP|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:wpqEL4ia/LUNdXSlQBRZxPfwCcY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y4W2	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y3T9	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y2X3	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y2W1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634|ensembl:ENSP00000433825	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005110.2|ensembl:ENSG00000054118(gene)|ensembl:ENST00000354618(transcript)|ensembl:ENST00000469141(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026667|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|refseq:NP_001308400.1|refseq:NP_001308402.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9Y221	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-749003|uniprotkb:Q9NZZ0|uniprotkb:B2RD04|ensembl:ENSP00000254940	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nip7_human(display_long)|uniprotkb:KD93(gene name synonym)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nucleolar pre-rRNA processing protein NIP7(gene name synonym)|uniprotkb:CGI-37(orf name)|uniprotkb:HSPC031(orf name)|uniprotkb:HSPC180(orf name)|uniprotkb:OK/SW-cl.76(orf name)|uniprotkb:OK/SW-cl.78(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001186363.1|refseq:NP_057185.1|ensembl:ENSG00000132603(gene)|ensembl:ENST00000254940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|mint:Q9Y221|rcsb pdb:1SQW|rcsb pdb:1T5Y|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:912ZyupB0CxH5w23chPh3IIICmY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9NQ55	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9H9P8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-11081371|uniprotkb:Q9BRR1|ensembl:ENSP00000267436|ensembl:ENSP00000405559	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:l2hdh_human(display_long)|uniprotkb:L2HGDH(gene name)|psi-mi:L2HGDH(display_short)|uniprotkb:C14orf160(gene name synonym)|uniprotkb:Duranin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_079160.1|refseq:XP_005268132.1|ensembl:ENSG00000087299(gene)|ensembl:ENST00000267436(transcript)|ensembl:ENST00000421284(transcript)|go:"GO:0003973"("(S)-2-hydroxy-acid oxidase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0047545"(2-hydroxyglutarate dehydrogenase activity)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188|reactome:R-HSA-880009	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:EMg3mk/BoaMCMi3AegPe/uX1/149606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9H6R4	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2514288|ensembl:ENSP00000297990|uniprotkb:Q5T5M4|uniprotkb:Q8TEZ0|uniprotkb:Q8TEZ1|uniprotkb:Q8TEY9|uniprotkb:Q7L4G6|uniprotkb:Q5T5M3|uniprotkb:Q8N6I0|uniprotkb:Q9H675	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nol6_human(display_long)|uniprotkb:NOL6(gene name)|psi-mi:NOL6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000165271(gene)|ensembl:ENST00000297990(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|mint:Q9H6R4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_075068.2|refseq:NP_631981.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:e1Waxlhmq+KTKwHTV13aWEpVF4k9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9H2D6	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9H0A0	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9BY89	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-8796741|intact:EBI-28980779|ensembl:ENSP00000351207|ensembl:ENSP00000385152|uniprotkb:B7ZW08|uniprotkb:Q5THZ5|uniprotkb:B0QYF2	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:k1671_human(display_long)|uniprotkb:KIAA1671(gene name)|psi-mi:KIAA1671(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000197077(gene)|ensembl:ENST00000358431(transcript)|ensembl:ENST00000406486(transcript)|interpro:IPR032764|interpro:IPR040006|ensembl:ENSP00000351207|ensembl:ENST00000401395|ensembl:ENSP00000385377|ensembl:ENSP00000385152|refseq:XP_005261850.1|refseq:XP_005261851.1|refseq:NP_001138678.1|refseq:XP_006724409.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:7mCSVXo/8Z2MUHqsxKKXrBvOe749606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9BV38	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q9BQ39	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q99848	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q96II8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q96HS1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q96H55	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-10983249|uniprotkb:Q59GS4|uniprotkb:Q9H5X2|ensembl:ENSP00000479518|ensembl:ENSP00000480242	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:myo19_human(display_long)|uniprotkb:MYO19(gene name)|psi-mi:MYO19(display_short)|uniprotkb:MYOHD1(gene name synonym)|uniprotkb:Myosin head domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001028752.1|refseq:NP_001157207.1|refseq:NP_079385.2|ensembl:ENSG00000278259(gene)|ensembl:ENSG00000278372(gene)|ensembl:ENST00000614623(transcript)|ensembl:ENST00000618519(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0051015"(actin filament binding)|go:"GO:0060002"(plus-end directed microfilament motor activity)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR036035|interpro:IPR036961|mint:Q96H55|reactome:R-HSA-9013419|reactome:R-HSA-9013425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:coJYx89cip3wKcsCF65cbMPBt7Y9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q92947	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q92769	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q8TDD1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:VzxEkRaOIND08jGJk3yyoztesjo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q8N5W9	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-716108|ensembl:ENSP00000331915	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rflb_human(display_long)|uniprotkb:RFLNB(gene name)|psi-mi:RFLNB(display_short)|uniprotkb:Regulator of filamin protein B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_874364.1|ensembl:ENSG00000183688(gene)|ensembl:ENST00000329099(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0005737"(cytoplasm)|go:"GO:0031005"(filamin binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0061182"(negative regulation of chondrocyte development)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:1900158"(negative regulation of bone mineralization involved in bone maturation)|interpro:IPR028215	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:DpCSj+OZdhckdJxOOi2ZuCn6E9Y9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q8N3V7	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352936|intact:EBI-28982054|ensembl:ENSP00000377789|ensembl:ENSP00000428378|uniprotkb:O15271|uniprotkb:Q9UPX1|uniprotkb:A5PKZ8|uniprotkb:D3DQG8	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:synpo_human(display_long)|uniprotkb:SYNPO(gene name)|psi-mi:SYNPO(display_short)|uniprotkb:KIAA1029(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000171992(gene)|ensembl:ENST00000394243(transcript)|ensembl:ENST00000522122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0097444"(spine apparatus)|go:"GO:1905355"(spine apparatus assembly)|interpro:IPR028753|mint:Q8N3V7|go:"GO:0098886"(modification of dendritic spine)|refseq:NP_001103444.1|refseq:NP_001159680.1|refseq:NP_001159681.1|refseq:NP_009217.3|ensembl:ENST00000307662|ensembl:ENSP00000302139|ensembl:ENSP00000377789|ensembl:ENST00000519664|ensembl:ENSP00000429268|ensembl:ENSP00000428378|refseq:XP_011535854.1|refseq:XP_005268427.1|refseq:XP_005268428.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:rCCRVthnF+JTqcwh9lD+GFoWIpo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q86UP2	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q71UM5	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q6YHK3	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2907947|uniprotkb:A5YKK4|uniprotkb:B2R948|uniprotkb:B3KW25|uniprotkb:Q0P6K7|uniprotkb:Q5SYA8|uniprotkb:Q5XUM7|uniprotkb:Q5XUM9|uniprotkb:Q6MZI7|uniprotkb:Q8N3A7|uniprotkb:Q8N915|uniprotkb:Q8TDJ2|uniprotkb:Q8TDJ3|ensembl:ENSP00000287097	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:cd109_human(display_long)|uniprotkb:CD109(gene name)|psi-mi:CD109(display_short)|uniprotkb:CPAMD7(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7(gene name synonym)|uniprotkb:150 kDa TGF-beta-1-binding protein(gene name synonym)|uniprotkb:Platelet-specific Gov antigen(gene name synonym)|uniprotkb:p180(gene name synonym)|uniprotkb:r150(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001153059.1|refseq:NP_001153060.1|refseq:NP_598000.2|refseq:XP_005248716.1|ensembl:ENSG00000156535(gene)|ensembl:ENST00000287097(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0072675"(osteoclast fusion)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR041555|interpro:IPR041813|reactome:R-HSA-114608|reactome:R-HSA-163125	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:hQo7zh7QCDnuvY9RzCHEymkmlZg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q6IBS0	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-722204|uniprotkb:Q9Y3F5|ensembl:ENSP00000303908	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:twf2_human(display_long)|uniprotkb:Twinfilin-1-like protein(gene name synonym)|uniprotkb:A6-related protein(gene name synonym)|uniprotkb:Protein tyrosine kinase 9-like(gene name synonym)|uniprotkb:TWF2(gene name)|psi-mi:TWF2(display_short)|uniprotkb:PTK9L(gene name synonym)|uniprotkb:MSTP011(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_009215.1|ensembl:ENSG00000247596(gene)|ensembl:ENST00000305533(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032420"(stereocilium)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|rcsb pdb:2VAC|rcsb pdb:2W0I|reactome:R-HSA-9662360|reactome:R-HSA-9662361	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:qWz7EmcCrpyHRA+wdEsiONY16zA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q6I9Y2	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:15M7nouxNuzlKZPawajrahz0LAY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q5W012	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21258084|ensembl:ENSP00000395448	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:q5w012_human(display_long)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000134453(gene)|ensembl:ENST00000437845(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR040052	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:61YxKA3gAuN6QCpAFyBysWjmYX89606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q5TCU3	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21260047|ensembl:ENSP00000367541	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:q5tcu3_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|ensembl:ENSG00000198467(gene)|ensembl:ENST00000329305(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|refseq:NP_001288155.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:kX9YiC30bV5utZmy/Goq1V6H6SU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q5T9A4	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:2W52iPQhTBU2apShm8xhfenV1mU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q58FF8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2961708	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q562R1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q2TAY7	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-298027|uniprotkb:Q9BU59|uniprotkb:Q9HA96|uniprotkb:Q9NVD1|ensembl:ENSP00000380336|uniprotkb:B4E3L0	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:smu1_human(display_long)|uniprotkb:Smu-1 suppressor of mec-8 and unc-52 protein homolog(gene name synonym)|uniprotkb:SMU1(gene name)|psi-mi:SMU1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENST00000397149(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q2TAY7|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6Q8F|rcsb pdb:6Q8I|rcsb pdb:6Q8J|ensembl:ENSG00000122692(gene)|refseq:NP_060695.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:zbTRfKynNIUSFY8IEqyYWh3JSho9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q27J81	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2557882|uniprotkb:Q6PK22|uniprotkb:Q86TR7|uniprotkb:Q9H6N1|uniprotkb:Q9BRM1|uniprotkb:Q27J83|uniprotkb:Q69YL8|uniprotkb:Q6P1X7|intact:EBI-28987364|ensembl:ENSP00000376410	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:inf2_human(display_long)|uniprotkb:INF2(gene name)|psi-mi:INF2(display_short)|uniprotkb:C14orf151(gene name synonym)|uniprotkb:C14orf173(gene name synonym)|uniprotkb:HBEBP2-binding protein C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001026884.3|refseq:NP_071934.3|refseq:NP_116103.1|ensembl:ENSG00000203485(gene)|ensembl:ENST00000392634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|mint:Q27J81|interpro:IPR027649|interpro:IPR042201|ensembl:ENST00000330634|ensembl:ENSP00000376406|ensembl:ENSP00000376410|ensembl:ENST00000398337|ensembl:ENSP00000381380	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Vtx6fZtKGr2qGWX70naf5REXWTw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q15393	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q15029	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q14980	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q14690	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-300028|uniprotkb:Q9H4P1|ensembl:ENSP00000358812|uniprotkb:Q86VQ8|uniprotkb:Q5W093|uniprotkb:Q2TA92|uniprotkb:Q6P2J3	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rrp5_human(display_long)|uniprotkb:PDCD11(gene name)|psi-mi:PDCD11(display_short)|uniprotkb:KIAA0185(gene name synonym)|uniprotkb:Programmed cell death protein 11(gene name synonym)|uniprotkb:NF-kappa-B-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000148843(gene)|ensembl:ENST00000369797(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032040"(small-subunit processome)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|mint:Q14690|rcsb pdb:1WI5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0006397"(mRNA processing)|refseq:NP_055791.1|refseq:XP_011537841.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:G3h7KMQzbRdyetWmb3uVBqXJWu09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q14643	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-465548|ensembl:ENSP00000497605|uniprotkb:Q14660|uniprotkb:Q99897|uniprotkb:E7EPX7|uniprotkb:E9PDE9	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:itpr1_human(display_long)|uniprotkb:ITPR1(gene name)|psi-mi:ITPR1(display_short)|uniprotkb:INSP3R1(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000150995(gene)|ensembl:ENST00000649015(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-418457|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001093422.2|refseq:NP_002213.5|refseq:XP_011531985.1|dip:DIP-29714N|refseq:NP_001161744.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:54BRt783vU5D9fCHNO5uFJy1N7I9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q14573	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q14247	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q13868	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q13823	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q13813	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q13492	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|intact:EBI-28967113|ensembl:ENSP00000377015|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENST00000356360|ensembl:ENSP00000348718|ensembl:ENSP00000377015|ensembl:ENST00000526033|ensembl:ENSP00000433846|ensembl:ENST00000528398|ensembl:ENSP00000434884|ensembl:ENST00000532317|ensembl:ENSP00000436958|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030412|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0032050"(clathrin heavy chain binding)|ensembl:ENSG00000073921(gene)|ensembl:ENST00000393346(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097753"(membrane bending)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902959"(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:0055072"(iron ion homeostasis)|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q13247	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q12874	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:fNjNguUOXqApr46rOAEpTs2geqY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q12792	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q10589	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q10471	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-10226985|uniprotkb:A8K1Y3|uniprotkb:C5HU00|uniprotkb:Q9NPY4|uniprotkb:B7Z8V8|ensembl:ENSP00000355632	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:galt2_human(display_long)|uniprotkb:GALNT2(gene name)|psi-mi:GALNT2(display_short)|uniprotkb:Polypeptide GalNAc transferase 2(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:"UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001278795.1|refseq:NP_004472.1|ensembl:ENSG00000143641(gene)|ensembl:ENST00000366672(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004653"(polypeptide N-acetylgalactosaminyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0018243"(protein O-linked glycosylation via threonine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051604"(protein maturation)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|rcsb pdb:2FFU|rcsb pdb:2FFV|rcsb pdb:4D0T|rcsb pdb:4D0Z|rcsb pdb:4D11|rcsb pdb:5AJN|rcsb pdb:5AJO|rcsb pdb:5AJP|rcsb pdb:5FV9|rcsb pdb:5NDF|rcsb pdb:6E7I|rcsb pdb:6EGS|rcsb pdb:6NQT|reactome:R-HSA-6811436|reactome:R-HSA-913709	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:z7hqeQjq7k5iQZfnLHZ4ioplKPU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q06265	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q03701	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q03001	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q01082	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q00653	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P62736	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P62136	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P61421	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P61163	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005727.1|ensembl:ENSG00000138107(gene)|ensembl:ENST00000369905(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P61158	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P60981	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-745191|uniprotkb:P18282|uniprotkb:Q5W166|uniprotkb:Q6IAW2|uniprotkb:B2R6N2|uniprotkb:B4DYA6|ensembl:ENSP00000246069	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:dest_human(display_long)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:DSTN(gene name)|psi-mi:DSTN(display_short)|uniprotkb:ACTDP(gene name synonym)|uniprotkb:DSN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001011546.1|refseq:NP_006861.1|refseq:XP_011527444.1|refseq:XP_011527445.1|refseq:XP_011527446.1|ensembl:ENSG00000125868(gene)|ensembl:ENST00000246069(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|interpro:IPR029924	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:3Z7XHPcWp0igOY70XOoGVfW5eBE9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P59998	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P54289	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-9690154|uniprotkb:Q17R45|uniprotkb:Q9UD80|uniprotkb:Q9UD81|uniprotkb:Q9UD82|ensembl:ENSP00000348589	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ca2d1_human(display_long)|uniprotkb:CACNA2D1(gene name)|psi-mi:CACNA2D1(display_short)|uniprotkb:CACNL2A(gene name synonym)|uniprotkb:CCHL2A(gene name synonym)|uniprotkb:MHS3(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha-2/delta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_000713.2|refseq:XP_005250627.1|refseq:XP_005250629.1|refseq:XP_005250630.1|refseq:XP_005250631.1|ensembl:ENSG00000153956(gene)|ensembl:ENST00000356253(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013608(VWA N-terminal)|interpro:IPR013680(Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region)|interpro:IPR036465	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:+IdPU9/mRR3gZjLuAHH7gXtgRlw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P52907	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P47756	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P46013	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P40937	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P31040	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P30044	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P28290	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-722905|uniprotkb:Q8N7H2|uniprotkb:Q7Z7L2|uniprotkb:Q8N1L3|uniprotkb:Q8N263|uniprotkb:Q8NEN5|uniprotkb:Q96E36|uniprotkb:Q68DA6|uniprotkb:Q96PW1|uniprotkb:A8K6T0|intact:EBI-28986959|ensembl:ENSP00000388731	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:itpi2_human(display_long)|uniprotkb:ITPRID2(gene name)|psi-mi:ITPRID2(display_short)|uniprotkb:CS1(gene name synonym)|uniprotkb:Cleavage signal-1 protein(gene name synonym)|uniprotkb:ITPR-interacting domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1927(gene name synonym)|uniprotkb:KRAP(gene name synonym)|uniprotkb:Ki-ras-induced actin-interacting protein(gene name synonym)|uniprotkb:SSFA2(gene name synonym)|uniprotkb:Sperm-specific antigen 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001123917.1|refseq:NP_006742.2|refseq:NP_001274432.1|refseq:NP_001274433.1|ensembl:ENST00000320370|ensembl:ENSP00000314669|ensembl:ENSP00000388731|dip:DIP-47271N|ensembl:ENSG00000138434(gene)|ensembl:ENST00000431877(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR026648|interpro:IPR029325|interpro:IPR029326|interpro:IPR043444	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:oLYBDg++fr2C4VnIkkP5xhll5dw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P28289	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P28288	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P23246	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P21333	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P20908	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2464511|uniprotkb:Q15094|uniprotkb:Q5SUX4|uniprotkb:A0A087WXW9|ensembl:ENSP00000360882	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:co5a1_human(display_long)|uniprotkb:COL5A1(gene name)|psi-mi:COL5A1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_000084.3|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043588"(skin development)|go:"GO:0045112"(integrin biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048592"(eye morphogenesis)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:1903225"(negative regulation of endodermal cell differentiation)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:1A89|rcsb pdb:1A9A|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|ensembl:ENSG00000130635(gene)|ensembl:ENST00000371817(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005588"(collagen type V trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0016477"(cell migration)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035989"(tendon development)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:VuIbevtKCbDH6f3KwEFMOe9nzKg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P14678-3	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264389	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:p14678-3(display_long)|uniprotkb:SNRPB(gene name)|psi-mi:SNRPB(display_short)|uniprotkb:COD(gene name synonym)|uniprotkb:SNRPB1(gene name synonym)|uniprotkb:Sm protein B/B'(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	intact:EBI-372458(isoform-parent)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Rt1KVbRSkeDgBG7mR7DPYkO8CbI9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P13010	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P12956	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P12268	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P11388	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-539628|uniprotkb:Q9HB26|uniprotkb:Q71UN1|uniprotkb:Q71UQ5|uniprotkb:Q9HB24|uniprotkb:Q9HB25|uniprotkb:Q9UP44|uniprotkb:Q9UQP9|uniprotkb:B2RTS1|intact:EBI-2556496|ensembl:ENSP00000411532	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:top2a_human(display_long)|uniprotkb:DNA topoisomerase II, alpha isozyme(gene name synonym)|uniprotkb:TOP2A(gene name)|psi-mi:TOP2A(display_short)|uniprotkb:TOP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001058.2|ensembl:ENSG00000131747(gene)|ensembl:ENST00000423485(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048511"(rhythmic process)|go:"GO:1905463"(negative regulation of DNA duplex unwinding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:P11388|rcsb pdb:1LWZ|rcsb pdb:1ZXM|rcsb pdb:4FM9|rcsb pdb:4R1F|rcsb pdb:5GWK|rcsb pdb:5NNE|rcsb pdb:6ZY5|rcsb pdb:6ZY6|rcsb pdb:6ZY7|rcsb pdb:6ZY8|reactome:R-HSA-1362277|reactome:R-HSA-4615885|rcsb pdb:1ZXN|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006266"(DNA ligation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019899"(enzyme binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-33887N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:WFhFsTLF3XG/CVgT4+TBNCovXiM9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P10909	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P09923	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P09211	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P07942	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P05783	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P04792	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N	-	-	crc64:1B4DC44A6F6606D5	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:P04062	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1564609|uniprotkb:B7Z5G2|uniprotkb:B7Z6S1|uniprotkb:J3KQG4|uniprotkb:J3KQK9|uniprotkb:Q16545|uniprotkb:Q4VX22|uniprotkb:Q6I9R6|uniprotkb:Q9UMJ8|uniprotkb:A8K796|ensembl:ENSP00000314508|ensembl:ENSP00000357357	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:glcm_human(display_long)|uniprotkb:Beta-glucocerebrosidase(gene name synonym)|uniprotkb:Acid beta-glucosidase(gene name synonym)|uniprotkb:D-glucosyl-N-acylsphingosine glucohydrolase(gene name synonym)|uniprotkb:Alglucerase(gene name synonym)|uniprotkb:Imiglucerase(gene name synonym)|uniprotkb:GBA(gene name)|psi-mi:GBA(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:GLUC(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001165282.1|refseq:NP_001165283.1|refseq:NP_000148.2|refseq:NP_001005741.1|refseq:NP_001005742.1|dip:DIP-38645N|ensembl:ENSG00000177628(gene)|ensembl:ENST00000327247(transcript)|ensembl:ENST00000368373(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009268"(response to pH)|go:"GO:0014004"(microglia differentiation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0033574"(response to testosterone)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043627"(response to estrogen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061744"(motor behavior)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901805"(beta-glucoside catabolic process)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1905037"(autophagosome organization)|go:"GO:1905165"(regulation of lysosomal protein catabolic process)|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033452|interpro:IPR033453|mint:P04062|rcsb pdb:1OGS|rcsb pdb:1Y7V|rcsb pdb:2F61|rcsb pdb:2J25|rcsb pdb:2NSX|rcsb pdb:2NT0|rcsb pdb:2NT1|rcsb pdb:2V3D|rcsb pdb:2V3E|rcsb pdb:2V3F|rcsb pdb:2VT0|rcsb pdb:2WCG|rcsb pdb:2WKL|rcsb pdb:2XWD|rcsb pdb:2XWE|rcsb pdb:3GXD|rcsb pdb:3GXF|rcsb pdb:3GXI|rcsb pdb:3GXM|rcsb pdb:3KE0|rcsb pdb:3KEH|rcsb pdb:3RIK|rcsb pdb:3RIL|rcsb pdb:5LVX|rcsb pdb:6MOZ|rcsb pdb:6Q1N|rcsb pdb:6Q1P|rcsb pdb:6Q6K|rcsb pdb:6Q6L|rcsb pdb:6Q6N|rcsb pdb:6TJJ|rcsb pdb:6TJK|rcsb pdb:6TJQ|rcsb pdb:6TN1|rcsb pdb:6YTP|rcsb pdb:6YTR|rcsb pdb:6YUT|rcsb pdb:6YV3|rcsb pdb:6Z39|rcsb pdb:6Z3I|reactome:R-HSA-1660662|reactome:R-HSA-390471	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:AWV635bfvuSWV1vflhTcun2riyk9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O96019	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O95478	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2852366|ensembl:ENSP00000483484	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O94906	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O76094	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O76021	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75955	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75934	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1050106|uniprotkb:Q6FGS0|ensembl:ENSP00000358554	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:spf27_human(display_long)|uniprotkb:Spliceosome-associated protein SPF 27(gene name synonym)|uniprotkb:Breast carcinoma-amplified sequence 2(gene name synonym)|uniprotkb:DNA amplified in mammary carcinoma 1 protein(gene name synonym)|uniprotkb:BCAS2(gene name)|psi-mi:BCAS2(display_short)|uniprotkb:DAM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005863.1|ensembl:ENSG00000116752(gene)|ensembl:ENST00000369541(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008409(Breast carcinoma amplified sequence 2)|mint:O75934|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-72163	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:yBhnwZOlEWsxnRIeuf/Z85O/QSQ9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75683	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75533	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75381	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-594898|uniprotkb:Q8WX51|uniprotkb:B2R7N1|uniprotkb:B3KML6|uniprotkb:B7Z1N2|intact:EBI-28983483|ensembl:ENSP00000349016	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pex14_human(display_long)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:Peroxin-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_004556.1|refseq:XP_011539882.1|ensembl:ENSP00000349016|ensembl:ENSG00000142655(gene)|ensembl:ENST00000356607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:O75381|rcsb pdb:2W84|rcsb pdb:2W85|rcsb pdb:4BXU|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:9RXZ+bR4fRStCHsMQihNHBhqmCo9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75369	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O75340	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O43143	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15226	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15160	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15145	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-351829|uniprotkb:O00554|ensembl:ENSP00000228825	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:arpc3_human(display_long)|uniprotkb:ARPC3(gene name)|psi-mi:ARPC3(display_short)|uniprotkb:ARC21(gene name synonym)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000111229(gene)|ensembl:ENST00000228825(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0061850"(growth cone leading edge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|mint:O15145|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001274151.1|refseq:NP_001265485.1|dip:DIP-33187N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:u4h1270mPo3E3GBrEurYtpUYTQM9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15144	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15143	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O15020	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-308449|uniprotkb:O14872|uniprotkb:O14873|ensembl:ENSP00000311489|ensembl:ENSP00000432568|ensembl:ENSP00000480692|ensembl:ENSP00000508362	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:sptn2_human(display_long)|uniprotkb:SPTBN2(gene name)|psi-mi:SPTBN2(display_short)|uniprotkb:KIAA0302(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:SCA5(gene name synonym)|uniprotkb:Spinocerebellar ataxia 5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000173898(gene)|ensembl:ENST00000309996(transcript)|ensembl:ENST00000533211(transcript)|ensembl:ENST00000611817(transcript)|ensembl:ENST00000647510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007416"(synapse assembly)|go:"GO:0008091"(spectrin)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:O15020|rcsb pdb:1WJM|rcsb pdb:1WYQ|rcsb pdb:6ANU|reactome:R-HSA-2132295|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|refseq:XP_005274249.1|refseq:XP_005274250.1|refseq:XP_006718734.1|refseq:XP_016873663.1|refseq:XP_016873664.1|refseq:XP_016873665.1|refseq:XP_016873666.1|refseq:XP_016873667.1|dip:DIP-47270N|refseq:NP_008877.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:Wfzccja70pnee8sDDc0TCmO6g0I9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O00567	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:O00411	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:K7ERC4	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21261583|ensembl:ENSP00000468198	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:k7erc4_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000173786(gene)|ensembl:ENST00000587679(transcript)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0042470"(melanosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:/Vn3QzpFFSK47wQIhlyDko6Eu389606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:K7ELP0	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264381|ensembl:ENSP00000466158	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:k7elp0_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000167460(gene)|ensembl:ENST00000589897(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:nf+uf96mgXvNBcYTa7wOUzPznr09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:I3L192	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264369|ensembl:ENSP00000458665	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:i3l192_human(display_long)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000172270(gene)|ensembl:ENST00000573216(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:s2h7cByi0kSTLQepPGxFhBMisl09606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:F5H6T1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264355|ensembl:ENSP00000437383	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:f5h6t1_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:hCG_21224(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENST00000542850(transcript)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|ensembl:ENSG00000138071(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:uXvYJxPxUJei6wa98fJ5pGPYy/U9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:E9PMS6	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-11030088|ensembl:ENSP00000431129	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:e9pms6_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000136153(gene)|ensembl:ENST00000526202(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:hXDMRMpvBWrOaT+cEyvVsA86jVs9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:E9PCT1	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264344|ensembl:ENSP00000391430	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:e9pct1_human(display_long)|uniprotkb:SRRM1(gene name)|psi-mi:SRRM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENST00000447431(transcript)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR036483|ensembl:ENSG00000133226(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:b/naZLZtbOLg29t9OBnBfZxNTgs9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:D3DTH7	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-14404730	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:d3dth7_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:hCG_28722(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036961	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:itPzNzrab9uJCfAjy/xZdQTXH6M9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:C9JYS8	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21260985|ensembl:ENSP00000413350	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:c9jys8_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000147140(gene)|ensembl:ENST00000413858(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:GtpR/hEDDTDI4cgs6RpvmIAC4oU9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:C9JVY5	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264337|ensembl:ENSP00000419268	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:c9jvy5_human(display_long)|uniprotkb:PALM2AKAP2(gene name)|psi-mi:PALM2AKAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000157654(gene)|ensembl:ENST00000480388(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:2feZz9Fntb5b9eMJVOgYVshLcFY9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:C9IYT0	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264032|ensembl:ENSP00000400542	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:c9iyt0_human(display_long)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000130826(gene)|ensembl:ENST00000413910(transcript)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR020103|interpro:IPR036974	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:JostiuQXQJjW7Ba14Z/GNsPFP089606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:A8K3Y5	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-21264330	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:a8k3y5_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR039999|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR041010	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:sOsf6bNg+ln+0tCDWvRys6RZ0/w9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:Q15154	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14108	uniprotkb:A1L390	intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896	intact:EBI-4401429|ensembl:ENSP00000247226|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790	psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym)	psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264396|imex:IM-26691-169	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828	ensembl:ENSG00000126822(gene)|ensembl:ENST00000247226(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|ensembl:ENSP00000247226|ensembl:ENST00000394691|ensembl:ENSP00000378183|refseq:XP_016876646.1|refseq:NP_001295076.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/04/15	rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606	rogid:+obep09w4klmkB8i13aA5FQW2609606	rigid:86leeQb2QF4ypI5MKoDSp6etIh4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q9Y6M0	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-7054564|ensembl:ENSP00000005995|ensembl:ENSP00000489315|uniprotkb:Q9NS34|intact:MINT-7712043|uniprotkb:Q9P2V6	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:test_human(display_long)|uniprotkb:PRSS21(gene name)|psi-mi:PRSS21(display_short)|uniprotkb:ESP1(gene name synonym)|uniprotkb:TEST1(gene name synonym)|uniprotkb:Serine protease 21(gene name synonym)|uniprotkb:Eosinophil serine protease 1(gene name synonym)|uniprotkb:UNQ266/PRO303(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	ensembl:ENSG00000007038(gene)|ensembl:ENSG00000282838(gene)|ensembl:ENST00000005995(transcript)|ensembl:ENST00000634351(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR034380|interpro:IPR043504|reactome:R-HSA-163125|refseq:NP_006790.1|refseq:NP_659205.1|refseq:NP_001257381.1|refseq:NP_659206.1	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:RnwT68uNM+AfH9NbI2v69lW4DzA9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q9UBS4	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q9HCN8	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-2339921|uniprotkb:Q9BRI5|uniprotkb:A2RUD3|ensembl:ENSP00000248958	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:sdf2l_human(display_long)|uniprotkb:SDF2L1(gene name)|psi-mi:SDF2L1(display_short)|uniprotkb:PWP1-interacting protein 8(gene name synonym)|uniprotkb:UNQ1941/PRO4424(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	refseq:NP_071327.2|ensembl:ENSG00000128228(gene)|ensembl:ENST00000248958(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|mint:Q9HCN8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:0vAPKCqCGpCARkmy7ZsTccxScgk9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q99470	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-2515769|ensembl:ENSP00000247020|uniprotkb:Q9BQ79	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:sdf2_human(display_long)|uniprotkb:SDF2(gene name)|psi-mi:SDF2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	ensembl:ENSG00000132581(gene)|ensembl:ENST00000247020(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|refseq:NP_008854.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:j0jeyDbvcmC8s+1awSiR7K/hyxo9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q8TEM1	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:Q15084	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:P30837	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-1237410|uniprotkb:Q8WX76|uniprotkb:Q9BV45|uniprotkb:B2R8F0|ensembl:ENSP00000366927	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:al1b1_human(display_long)|uniprotkb:ALDH1B1(gene name)|psi-mi:ALDH1B1(display_short)|uniprotkb:ALDH5(gene name synonym)|uniprotkb:ALDHX(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member B1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	refseq:NP_000683.3|ensembl:ENSG00000137124(gene)|ensembl:ENST00000377698(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P30837|reactome:R-HSA-71384|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:esHIXlANuM3Gmcr8ldyTq/nAyUM9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:P27824	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:H0Y8H0	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-21263869|ensembl:ENSP00000421026	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:h0y8h0_human(display_long)|uniprotkb:DDX60L(gene name)|psi-mi:DDX60L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	go:"GO:0003676"(nucleic acid binding)|ensembl:ENSG00000181381(gene)|ensembl:ENST00000505863(transcript)|go:"GO:0005524"(ATP binding)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:c76HoovU2ZqbWWS2BJuAp+7IgSo9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:J3KSN0	uniprotkb:E9PK09	intact:EBI-21259955|ensembl:ENSP00000462563	intact:EBI-21264788|ensembl:ENSP00000431734	psi-mi:j3ksn0_human(display_long)|uniprotkb:SECTM1(gene name)|psi-mi:SECTM1(display_short)	psi-mi:e9pk09_human(display_long)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264801|imex:IM-26691-153	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141574(gene)|ensembl:ENST00000583093(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0006955"(immune response)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033231|interpro:IPR036179	go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR026668|interpro:IPR029199|go:"GO:0016607"(nuclear speck)|ensembl:ENSG00000029363(gene)|ensembl:ENST00000529826(transcript)|go:"GO:0006915"(apoptotic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:4lca94+xwN+V00T0DSf8VvWQT2c9606	rogid:E1N3gVC4N44GblyMGURs8hkJsWA9606	rigid:Bo8WdWJHbf3PmURsqyansqq7LwI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P05121	uniprotkb:Q14697	intact:EBI-953978|ensembl:ENSP00000223095|uniprotkb:B7Z4S0|uniprotkb:F8WD53	intact:EBI-348004|ensembl:ENSP00000349053|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0	psi-mi:pai1_human(display_long)|uniprotkb:Endothelial plasminogen activator inhibitor(gene name synonym)|uniprotkb:SERPINE1(gene name)|psi-mi:SERPINE1(display_short)|uniprotkb:PAI1(gene name synonym)|uniprotkb:PLANH1(gene name synonym)|uniprotkb:Serpin E1(gene name synonym)	psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264837|imex:IM-26691-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106366(gene)|ensembl:ENST00000223095(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035491"(positive regulation of leukotriene production involved in inflammatory response)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090399"(replicative senescence)|go:"GO:0097187"(dentinogenesis)|go:"GO:1901331"(positive regulation of odontoblast differentiation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1A7C|rcsb pdb:1B3K|interpro:IPR023795|rcsb pdb:1C5G|rcsb pdb:1DB2|rcsb pdb:1DVM|rcsb pdb:1DVN|rcsb pdb:1LJ5|rcsb pdb:1OC0|rcsb pdb:3CVM|rcsb pdb:3EOX|rcsb pdb:3PB1|rcsb pdb:3Q02|rcsb pdb:3Q03|rcsb pdb:3R4L|rcsb pdb:3UT3|rcsb pdb:4AQH|rcsb pdb:4G8O|rcsb pdb:4G8R|rcsb pdb:4IC0|rcsb pdb:5BRR|rcsb pdb:5ZLZ|rcsb pdb:6GWN|rcsb pdb:6GWP|rcsb pdb:6GWQ|rcsb pdb:6I8S|rcsb pdb:6ZRV|rcsb pdb:7AQF|rcsb pdb:7AQG|rcsb pdb:9PAI|reactome:R-HSA-114608|reactome:R-HSA-1368108|reactome:R-HSA-2173796|reactome:R-HSA-3000178|reactome:R-HSA-75205|refseq:NP_000593.1	ensembl:ENSG00000089597(gene)|ensembl:ENST00000356638(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q14697|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9694548|reactome:R-HSA-9683686|refseq:NP_938148.1|refseq:NP_938149.2|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:uKgGVfJUEf7zIyf5CgJGIf5TJco9606	rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606	rigid:1O3KnTICC/oExya4zYeG9aYBXdQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P05121	uniprotkb:P39687	intact:EBI-953978|ensembl:ENSP00000223095|uniprotkb:B7Z4S0|uniprotkb:F8WD53	intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864	psi-mi:pai1_human(display_long)|uniprotkb:Endothelial plasminogen activator inhibitor(gene name synonym)|uniprotkb:SERPINE1(gene name)|psi-mi:SERPINE1(display_short)|uniprotkb:PAI1(gene name synonym)|uniprotkb:PLANH1(gene name synonym)|uniprotkb:Serpin E1(gene name synonym)	psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264837|imex:IM-26691-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106366(gene)|ensembl:ENST00000223095(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035491"(positive regulation of leukotriene production involved in inflammatory response)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090399"(replicative senescence)|go:"GO:0097187"(dentinogenesis)|go:"GO:1901331"(positive regulation of odontoblast differentiation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1A7C|rcsb pdb:1B3K|interpro:IPR023795|rcsb pdb:1C5G|rcsb pdb:1DB2|rcsb pdb:1DVM|rcsb pdb:1DVN|rcsb pdb:1LJ5|rcsb pdb:1OC0|rcsb pdb:3CVM|rcsb pdb:3EOX|rcsb pdb:3PB1|rcsb pdb:3Q02|rcsb pdb:3Q03|rcsb pdb:3R4L|rcsb pdb:3UT3|rcsb pdb:4AQH|rcsb pdb:4G8O|rcsb pdb:4G8R|rcsb pdb:4IC0|rcsb pdb:5BRR|rcsb pdb:5ZLZ|rcsb pdb:6GWN|rcsb pdb:6GWP|rcsb pdb:6GWQ|rcsb pdb:6I8S|rcsb pdb:6ZRV|rcsb pdb:7AQF|rcsb pdb:7AQG|rcsb pdb:9PAI|reactome:R-HSA-114608|reactome:R-HSA-1368108|reactome:R-HSA-2173796|reactome:R-HSA-3000178|reactome:R-HSA-75205|refseq:NP_000593.1	refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:uKgGVfJUEf7zIyf5CgJGIf5TJco9606	rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606	rigid:1O3KnTICC/oExya4zYeG9aYBXdQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P05121	uniprotkb:P30040	intact:EBI-953978|ensembl:ENSP00000223095|uniprotkb:B7Z4S0|uniprotkb:F8WD53	intact:EBI-946830|uniprotkb:Q3MJC3|uniprotkb:Q6FHT4|uniprotkb:C9J183|ensembl:ENSP00000261735	psi-mi:pai1_human(display_long)|uniprotkb:Endothelial plasminogen activator inhibitor(gene name synonym)|uniprotkb:SERPINE1(gene name)|psi-mi:SERPINE1(display_short)|uniprotkb:PAI1(gene name synonym)|uniprotkb:PLANH1(gene name synonym)|uniprotkb:Serpin E1(gene name synonym)	psi-mi:erp29_human(display_long)|uniprotkb:ERP29(gene name)|psi-mi:ERP29(display_short)|uniprotkb:C12orf8(gene name synonym)|uniprotkb:ERP28(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 31(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 28(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264837|imex:IM-26691-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106366(gene)|ensembl:ENST00000223095(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035491"(positive regulation of leukotriene production involved in inflammatory response)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090399"(replicative senescence)|go:"GO:0097187"(dentinogenesis)|go:"GO:1901331"(positive regulation of odontoblast differentiation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1A7C|rcsb pdb:1B3K|interpro:IPR023795|rcsb pdb:1C5G|rcsb pdb:1DB2|rcsb pdb:1DVM|rcsb pdb:1DVN|rcsb pdb:1LJ5|rcsb pdb:1OC0|rcsb pdb:3CVM|rcsb pdb:3EOX|rcsb pdb:3PB1|rcsb pdb:3Q02|rcsb pdb:3Q03|rcsb pdb:3R4L|rcsb pdb:3UT3|rcsb pdb:4AQH|rcsb pdb:4G8O|rcsb pdb:4G8R|rcsb pdb:4IC0|rcsb pdb:5BRR|rcsb pdb:5ZLZ|rcsb pdb:6GWN|rcsb pdb:6GWP|rcsb pdb:6GWQ|rcsb pdb:6I8S|rcsb pdb:6ZRV|rcsb pdb:7AQF|rcsb pdb:7AQG|rcsb pdb:9PAI|reactome:R-HSA-114608|reactome:R-HSA-1368108|reactome:R-HSA-2173796|reactome:R-HSA-3000178|reactome:R-HSA-75205|refseq:NP_000593.1	refseq:NP_006808.1|refseq:NP_001029197.1|ensembl:ENSG00000089248(gene)|ensembl:ENST00000261735(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043335"(protein unfolding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR011679(Endoplasmic reticulum, protein ERp29, C-terminal)|interpro:IPR012883(ERp29, N-terminal)|interpro:IPR016855(Endoplasmic reticulum, protein ERp29)|interpro:IPR036249|interpro:IPR036356|rcsb pdb:2QC7|rcsb pdb:5V8Z|rcsb pdb:5V90	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:uKgGVfJUEf7zIyf5CgJGIf5TJco9606	rogid:5+uNyIlUU6txfPlS4DSPunpjz3M9606	rigid:1O3KnTICC/oExya4zYeG9aYBXdQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P05121	uniprotkb:P14625	intact:EBI-953978|ensembl:ENSP00000223095|uniprotkb:B7Z4S0|uniprotkb:F8WD53	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:pai1_human(display_long)|uniprotkb:Endothelial plasminogen activator inhibitor(gene name synonym)|uniprotkb:SERPINE1(gene name)|psi-mi:SERPINE1(display_short)|uniprotkb:PAI1(gene name synonym)|uniprotkb:PLANH1(gene name synonym)|uniprotkb:Serpin E1(gene name synonym)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264837|imex:IM-26691-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106366(gene)|ensembl:ENST00000223095(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035491"(positive regulation of leukotriene production involved in inflammatory response)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090399"(replicative senescence)|go:"GO:0097187"(dentinogenesis)|go:"GO:1901331"(positive regulation of odontoblast differentiation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1A7C|rcsb pdb:1B3K|interpro:IPR023795|rcsb pdb:1C5G|rcsb pdb:1DB2|rcsb pdb:1DVM|rcsb pdb:1DVN|rcsb pdb:1LJ5|rcsb pdb:1OC0|rcsb pdb:3CVM|rcsb pdb:3EOX|rcsb pdb:3PB1|rcsb pdb:3Q02|rcsb pdb:3Q03|rcsb pdb:3R4L|rcsb pdb:3UT3|rcsb pdb:4AQH|rcsb pdb:4G8O|rcsb pdb:4G8R|rcsb pdb:4IC0|rcsb pdb:5BRR|rcsb pdb:5ZLZ|rcsb pdb:6GWN|rcsb pdb:6GWP|rcsb pdb:6GWQ|rcsb pdb:6I8S|rcsb pdb:6ZRV|rcsb pdb:7AQF|rcsb pdb:7AQG|rcsb pdb:9PAI|reactome:R-HSA-114608|reactome:R-HSA-1368108|reactome:R-HSA-2173796|reactome:R-HSA-3000178|reactome:R-HSA-75205|refseq:NP_000593.1	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:uKgGVfJUEf7zIyf5CgJGIf5TJco9606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:1O3KnTICC/oExya4zYeG9aYBXdQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8IXI1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q7Z6Z7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9GZP9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92643	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:U3KQ84	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262903|ensembl:ENSP00000475634	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:u3kq84_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000244038(gene)|ensembl:ENST00000464364(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:NGgqak8QRgCkgA8i0YquXgL3f909606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:U3KPY4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21264921|ensembl:ENSP00000475354	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:u3kpy4_human(display_long)|uniprotkb:TMEM259(gene name)|psi-mi:TMEM259(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENST00000592590(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019144|ensembl:ENSG00000182087(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:SBjjFH04QU6YQV4xihVqkS5uBwU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y6H1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y679	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y678	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y5L4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y5L0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y5J9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y5A9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918|ensembl:ENSP00000444660	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492(gene)|ensembl:ENST00000373812(transcript)|ensembl:ENST00000542507(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|mint:Q9Y5A9|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:4RDN	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y3E5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y3D0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y383	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9Y241	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UN37	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UKV5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UJZ1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UI10	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UHI6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UBS4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9UBF2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9P035	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NZ01	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NXW2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NW81	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21264879|ensembl:ENSP00000221943|uniprotkb:B4DDC0|uniprotkb:B4DMZ4|uniprotkb:B4DP55|uniprotkb:B4DXE8|uniprotkb:F5H4W7|uniprotkb:K7EMF6|uniprotkb:Q96D43	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:dmac2_human(display_long)|uniprotkb:DMAC2(gene name)|psi-mi:DMAC2(display_short)|uniprotkb:ATP5SL(gene name synonym)|uniprotkb:ATP synthase subunit s-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000105341(gene)|ensembl:ENST00000221943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR032675|refseq:NP_001161339.1|refseq:NP_001161340.1|refseq:NP_001161341.1|refseq:NP_001161342.1|refseq:NP_001161343.1|refseq:NP_001307767.1|refseq:NP_001307769.1|refseq:NP_001307770.1|refseq:NP_060505.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:KUzYgXq0j1uGxOZpsoGu7+Pd69E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NVI1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NTJ5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NR50	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NP72	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9H845	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9H7F0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9H4A6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9H078	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9C0E8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1047206|ensembl:ENSP00000272748|uniprotkb:Q2M2V8|uniprotkb:Q2YD99|uniprotkb:Q658W8|uniprotkb:Q8N5V9|uniprotkb:Q96MS5|uniprotkb:B7ZLA8	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:lnp_human(display_long)|uniprotkb:ER junction formation factor lunapark(gene name synonym)|uniprotkb:LNPK(gene name)|psi-mi:LNPK(display_short)|uniprotkb:KIAA1715(gene name synonym)|uniprotkb:LNP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000144320(gene)|ensembl:ENST00000272748(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|refseq:NP_085153.1|refseq:NP_001291937.1|refseq:NP_001291938.1|refseq:NP_001291940.1|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060173"(limb development)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR019273|interpro:IPR040115|refseq:XP_006712846.1|refseq:XP_016860544.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:7iBa9RbcYnDjAjIU4v0rez5Bhn49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BXW9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BUF5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BTX1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BSJ2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BRR3	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3922384|uniprotkb:Q49AQ4|ensembl:ENSP00000363980|ensembl:ENSP00000363981|ensembl:ENSP00000363984	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pgap4_human(display_long)|uniprotkb:PGAP4(gene name)|psi-mi:PGAP4(display_short)|uniprotkb:C9orf125(gene name synonym)|uniprotkb:Post-GPI attachment to proteins GalNAc transferase 4(gene name synonym)|uniprotkb:TMEM246(gene name synonym)|uniprotkb:Transmembrane protein 246(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_115718.1|ensembl:ENST00000374847(transcript)|ensembl:ENST00000374848(transcript)|ensembl:ENST00000374851(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|interpro:IPR029675|ensembl:ENSG00000165152(gene)|refseq:NP_001290036.1|refseq:NP_001290037.1|refseq:XP_016870695.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ny1picQHrWCnaUmwB54mBIzNfd09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BRK5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1389808|uniprotkb:Q8NBQ3|uniprotkb:Q9NZP7|uniprotkb:B1AME5|uniprotkb:B2RDF1|uniprotkb:B4DSM1|uniprotkb:Q53G52|uniprotkb:Q53HQ9|uniprotkb:Q96AA1|uniprotkb:Q9UN53|intact:EBI-2511482|uniprotkb:B1AME6	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cab45_human(display_long)|uniprotkb:Stromal cell-derived factor 4(gene name synonym)|uniprotkb:SDF4(gene name)|psi-mi:SDF4(display_short)|uniprotkb:CAB45(gene name synonym)|uniprotkb:PSEC0034(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_057631.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_011539858.1|interpro:IPR027240|mint:Q9BRK5|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0021549"(cerebellum development)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070625"(zymogen granule exocytosis)|go:"GO:0099558"(maintenance of synapse structure)|refseq:NP_057260.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:wQ0Ov1MDf6p0BmUCZRAS+Na/ERc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BQE3	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1103245|ensembl:ENSP00000301072	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9BQ95	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q99729	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q99653	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q99623	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96T76	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96S66	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96S52	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96Q15	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:u7doCYezlcCUKq//xhk0TZ2TD009606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96P70	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96KA5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96K37	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-720094|uniprotkb:Q8NBQ2|uniprotkb:Q96JV7|ensembl:ENSP00000470652	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:s35e1_human(display_long)|uniprotkb:SLC35E1(gene name)|psi-mi:SLC35E1(display_short)|uniprotkb:PSEC0038(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_079157.3|ensembl:ENSG00000127526(gene)|ensembl:ENST00000595753(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004853(Protein of unknown function DUF250)|go:"GO:0015297"(antiporter activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:UelDuXaGT2mBsXghGzSX5aKisj89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96JJ7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96DZ1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96D53	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96CS3	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96CN4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96AQ6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96AG4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q96A33	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q969Z0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q969N2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92973	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92945	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92572	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-4289921|uniprotkb:Q6ICQ2|uniprotkb:O00676|uniprotkb:O00727|uniprotkb:Q53XL4|uniprotkb:O00647|uniprotkb:O00721|ensembl:ENSP00000325369	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ap3s1_human(display_long)|uniprotkb:AP3S1(gene name)|psi-mi:AP3S1(display_short)|uniprotkb:Sigma-3A-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3a(gene name synonym)|uniprotkb:CLAPS3(gene name synonym)|uniprotkb:AP-3 complex subunit sigma-3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit sigma-1(gene name synonym)|uniprotkb:Clathrin-associated/assembly/adaptor protein, small 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000177879(gene)|ensembl:ENST00000316788(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027155|reactome:R-HSA-432722|refseq:NP_001275.1|refseq:NP_001002924.2|refseq:NP_001305019.1|refseq:NP_001305020.1|refseq:NP_001305022.1|refseq:NP_001305023.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fRNNY4ETqt4Qv6CTQqFxeIk8Syc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92543	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-728232|ensembl:ENSP00000265909|uniprotkb:E9PKB9|uniprotkb:Q8IV55	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:snx19_human(display_long)|uniprotkb:SNX19(gene name)|psi-mi:SNX19(display_short)|uniprotkb:KIAA0254(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000120451(gene)|ensembl:ENST00000265909(transcript)|refseq:NP_055573.2|refseq:NP_001334847.1|refseq:NP_001334848.1|refseq:NP_001334849.1|refseq:NP_001334850.1|refseq:NP_001334851.1|refseq:NP_001334852.1|refseq:NP_001334853.1|refseq:NP_001334854.1|refseq:NP_001334855.1|refseq:NP_001334856.1|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0030073"(insulin secretion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1990502"(dense core granule maturation)|interpro:IPR001683(Phox-like)|interpro:IPR003114(PX-associated)|interpro:IPR013937(Sorting nexin, C-terminal)|interpro:IPR034908|interpro:IPR036871|interpro:IPR037909	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:K3NS39vRx+FYSZXGpylwf32l0ug9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q92504	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1051105|uniprotkb:Q5STP8|uniprotkb:Q9UIQ0|uniprotkb:B0UXF6|ensembl:ENSP00000363807|ensembl:ENSP00000363809|ensembl:ENSP00000372700|ensembl:ENSP00000372701|ensembl:ENSP00000389623|ensembl:ENSP00000391735|ensembl:ENSP00000403583|ensembl:ENSP00000407093|ensembl:ENSP00000410656|ensembl:ENSP00000413027|ensembl:ENSP00000414145|ensembl:ENSP00000416439	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:s39a7_human(display_long)|uniprotkb:Solute carrier family 39 member 7(gene name synonym)|uniprotkb:Histidine-rich membrane protein Ke4(gene name synonym)|uniprotkb:SLC39A7(gene name)|psi-mi:SLC39A7(display_short)|uniprotkb:HKE4(gene name synonym)|uniprotkb:RING5(gene name synonym)|uniprotkb:Zrt-, Irt-like protein 7(gene name synonym)|uniprotkb:Really interesting new gene 5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001070984.1|refseq:NP_008910.2|refseq:NP_001275706.1|ensembl:ENSG00000112473(gene)|ensembl:ENSG00000206288(gene)|ensembl:ENSG00000224399(gene)|ensembl:ENSG00000226614(gene)|ensembl:ENSG00000227402(gene)|ensembl:ENSG00000229802(gene)|ensembl:ENST00000374675(transcript)|ensembl:ENST00000374677(transcript)|ensembl:ENST00000383213(transcript)|ensembl:ENST00000383214(transcript)|ensembl:ENST00000416369(transcript)|ensembl:ENST00000418477(transcript)|ensembl:ENST00000423043(transcript)|ensembl:ENST00000441854(transcript)|ensembl:ENST00000441953(transcript)|ensembl:ENST00000443773(transcript)|ensembl:ENST00000456261(transcript)|ensembl:ENST00000431735(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR003689(Zinc/iron permease)|mint:Q92504|reactome:R-HSA-442380	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:br+gKDgDx3uyEg/kbJ6JCqJaTXA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8WZ42	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8WWC4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8WVX9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8TEM1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8NEW0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1043569|uniprotkb:Q8TCH2|ensembl:ENSP00000350278|ensembl:ENSP00000359130|uniprotkb:B2R949|uniprotkb:D3DT61	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:znt7_human(display_long)|uniprotkb:SLC30A7(gene name)|psi-mi:SLC30A7(display_short)|uniprotkb:ZNT7(gene name synonym)|uniprotkb:ZNTL2(gene name synonym)|uniprotkb:Znt-like transporter 2(gene name synonym)|uniprotkb:Solute carrier family 30 member 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000162695(gene)|ensembl:ENST00000357650(transcript)|ensembl:ENST00000370112(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006829"(zinc ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|reactome:R-HSA-264876|reactome:R-HSA-435368|go:"GO:0032119"(sequestering of zinc ion)|refseq:NP_001138356.1|refseq:NP_598003.2|refseq:XP_016855889.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:/okPwOjluCDoM8a5uHoixAyRc8E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8IXB1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q8IV08	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|ensembl:ENSP00000348901|ensembl:ENSP00000386293|ensembl:ENSP00000386938|ensembl:ENSP00000387022|ensembl:ENSP00000387050	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pld3_human(display_long)|uniprotkb:Choline phosphatase 3(gene name synonym)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D3(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001278240.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:NP_001026866.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|ensembl:ENSG00000105223(gene)|ensembl:ENST00000356508(transcript)|ensembl:ENST00000409281(transcript)|ensembl:ENST00000409419(transcript)|ensembl:ENST00000409587(transcript)|ensembl:ENST00000409735(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002376"(immune system process)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:XP_006723185.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q86VR2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-10192441|uniprotkb:B3KR75|intact:EBI-28968873|ensembl:ENSP00000309432	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:retr3_human(display_long)|uniprotkb:RETREG3(gene name)|psi-mi:RETREG3(display_short)|uniprotkb:FAM134C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000309432|refseq:NP_835227.1|ensembl:ENSG00000141699(gene)|ensembl:ENST00000309428(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061709"(reticulophagy)|interpro:IPR033361|interpro:IPR043384|dip:DIP-61578N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:KqWyZAyKEB6J9lUId4BSZK2nQXQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q86VP6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q6YHU6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2824523|uniprotkb:Q3KR04|uniprotkb:Q53RC6|uniprotkb:Q6ZU38|uniprotkb:Q9H6W7|uniprotkb:Q6YHU2|uniprotkb:Q9C096|uniprotkb:Q96I88|uniprotkb:Q8TAU8|uniprotkb:Q9H6U0|uniprotkb:B7WNS6|uniprotkb:Q53TB2|uniprotkb:A8K1V8|intact:EBI-3213832|uniprotkb:Q9BZF7|ensembl:ENSP00000385995|ensembl:ENSP00000386088|uniprotkb:Q8IY32	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:thada_human(display_long)|uniprotkb:THADA(gene name)|psi-mi:THADA(display_short)|uniprotkb:GITA(gene name synonym)|uniprotkb:KIAA1767(gene name synonym)|uniprotkb:Gene inducing thyroid adenomas protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001332854.1|ensembl:ENSG00000115970(gene)|ensembl:ENST00000405006(transcript)|ensembl:ENST00000405975(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019442|rcsb pdb:5T6Y|reactome:R-HSA-6782315|refseq:XP_006712128.1|refseq:NP_001077422.1|refseq:NP_071348.3|refseq:NP_001258572.1|refseq:NP_001258573.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:HLP/DNXyeZkkWzwOjvl/6A+U6eU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q6P582	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2558548|uniprotkb:Q8WVB2|uniprotkb:Q3SWV8|ensembl:ENSP00000311500	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:mzt2a_human(display_long)|uniprotkb:FAM128A(gene name synonym)|uniprotkb:MOZART2A(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A(gene name synonym)|uniprotkb:MZT2A(gene name)|psi-mi:MZT2A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001078834.1|ensembl:ENSG00000173272(gene)|ensembl:ENST00000309451(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|interpro:IPR024332|rcsb pdb:6X0V|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:dCqJOdxX0GGsuNM2rTxgktV4u9s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q6P1M0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q6IAA8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-715385|uniprotkb:Q8WZ09|uniprotkb:Q9NWT0|ensembl:ENSP00000278671	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ltor1_human(display_long)|uniprotkb:LAMTOR1(gene name)|psi-mi:LAMTOR1(display_short)|uniprotkb:PP7157(orf name)|uniprotkb:p27Kip1-releasing factor from RhoA(gene name synonym)|uniprotkb:C11orf59(gene name synonym)|uniprotkb:Lipid raft adaptor protein p18(gene name synonym)|uniprotkb:Protein associated with DRMs and endosomes(gene name synonym)|uniprotkb:PDRO(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_060377.1|ensembl:ENSG00000149357(gene)|ensembl:ENST00000278671(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010872"(regulation of cholesterol esterification)|go:"GO:0010874"(regulation of cholesterol efflux)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045121"(membrane raft)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0060620"(regulation of cholesterol import)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR028209|rcsb pdb:5X6U|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:5X6V|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9639288|dip:DIP-39650N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:qOdH2HiC+MXwRS2+L8/XgkTRDeo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q68DH5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-20858131|ensembl:ENSP00000296603|uniprotkb:B3KRB6|uniprotkb:Q9NTC7	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:lmbd2_human(display_long)|uniprotkb:LMBRD2(gene name)|psi-mi:LMBRD2(display_short)|uniprotkb:LMBR1 domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000164187(gene)|ensembl:ENST00000296603(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071875"(adrenergic receptor signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|mint:Q68DH5|refseq:NP_001007528.1|refseq:XP_011512464.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:q2WB24Dd8SLHl38AcRDvDE/k8zs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5TB53	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21260364|ensembl:ENSP00000401152	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q5tb53_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0016021"(integral component of membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensembl:ENSG00000077147(gene)|ensembl:ENST00000443638(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:T1DWVoePJSFkdgudFKdtzv/VaCg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5TAQ9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5T4S7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5T160	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1050546|uniprotkb:Q96FU5|uniprotkb:Q9H8K8|uniprotkb:B2RDT7|ensembl:ENSP00000358549	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:syrm_human(display_long)|uniprotkb:RARS2(gene name)|psi-mi:RARS2(display_short)|uniprotkb:RARSL(gene name synonym)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_064716.2|ensembl:ENSG00000146282(gene)|ensembl:ENST00000369536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q5T160|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:jslLCkjYCriiVlR94nHAhNIYVeY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5SZE2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262890|ensembl:ENSP00000394012	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q5sze2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000143418(gene)|ensembl:ENST00000457392(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ka5Rf62LvM6VKgqeYwzYWklPFHc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5JYR7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262879|ensembl:ENSP00000362735	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q5jyr7_human(display_long)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|ensembl:ENSG00000118705(gene)|ensembl:ENST00000373632(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:XtgQttct6NCg4alvIHMvEzDw4Ak9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5JTH9	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5JSD2	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5HYI8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000144840(gene)|ensembl:ENST00000273375(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:1903059"(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|go:"GO:0050821"(protein stabilization)|refseq:NP_776186.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5C9Z4	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2685618|uniprotkb:Q96I08|ensembl:ENSP00000275820	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:nom1_human(display_long)|uniprotkb:C7orf3(gene name synonym)|uniprotkb:SGD1 homolog(gene name synonym)|uniprotkb:NOM1(gene name)|psi-mi:NOM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_612409.1|ensembl:ENSG00000146909(gene)|ensembl:ENST00000275820(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0048820"(hair follicle maturation)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:Q5C9Z4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:1LScd95yytIZJ1/UFg9WTUiCmqg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q5BJH7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q53GQ0	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q53G47	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262404	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q53g47_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0006376"(mRNA splice site selection)|go:"GO:0005685"(U1 snRNP)|go:"GO:0003729"(mRNA binding)|interpro:IPR004882(LUC7 related)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:w61VEyTmEJQuiZVLFC/j6siDV/w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q3ZCQ8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q3ZCM7	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q32Q12	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-11897132|ensembl:ENSP00000451932	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q32q12_human(display_long)|uniprotkb:NME1-NME2(gene name)|psi-mi:NME1-NME2(display_short)|uniprotkb:hCG_2001850(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000011052(gene)|ensembl:ENST00000555572(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:F9Z+VsBFIAci0CnyPOHlWo7SinY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q16531	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15758	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15645	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15629	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1788852|uniprotkb:B4E0K2|ensembl:ENSP00000262213	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tram1_human(display_long)|uniprotkb:TRAM1(gene name)|psi-mi:TRAM1(display_short)|uniprotkb:TRAM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_055109.1|refseq:NP_001304733.1|refseq:NP_001304734.1|dip:DIP-45978N|ensembl:ENSG00000067167(gene)|ensembl:ENST00000262213(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016447(Translocation associated membrane protein)|mint:Q15629|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:MsD+t4fSxQllDp5wobRI5mAL5+49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15392	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-5457558|uniprotkb:B7Z817|ensembl:ENSP00000360316|ensembl:ENSP00000416585|uniprotkb:D3DQ51|uniprotkb:Q9HBA8|intact:EBI-10964490	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:dhc24_human(display_long)|uniprotkb:DHCR24(gene name)|psi-mi:DHCR24(display_short)|uniprotkb:KIAA0018(gene name synonym)|uniprotkb:24-dehydrocholesterol reductase(gene name synonym)|uniprotkb:Diminuto/dwarf1 homolog(gene name synonym)|uniprotkb:Seladin-1(gene name synonym)|uniprotkb:3-beta-hydroxysterol Delta-24-reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000116133(gene)|ensembl:ENST00000371269(transcript)|ensembl:ENST00000436604(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0050614"(delta24-sterol reductase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061024"(membrane organization)|go:"GO:0071949"(FAD binding)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318|interpro:IPR040165|go:"GO:0005737"(cytoplasm)|mint:Q15392|reactome:R-HSA-6807047|reactome:R-HSA-6807062|refseq:NP_055577.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kg8bxZHxFFTUmvP9UQMeVFRNWQM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15165	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3909798|ensembl:ENSP00000222572|ensembl:ENSP00000488838|uniprotkb:O15114|uniprotkb:B4DJD5|uniprotkb:Q5FBX7|uniprotkb:O15115|uniprotkb:B2RCP9|uniprotkb:Q86YL0|uniprotkb:O75856|uniprotkb:A4D1H7|intact:EBI-10966394	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pon2_human(display_long)|uniprotkb:PON2(gene name)|psi-mi:PON2(display_short)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000105854(gene)|ensembl:ENST00000222572(transcript)|ensembl:ENST00000633531(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009636"(response to toxic substance)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|mint:Q15165|reactome:R-HSA-2142688|refseq:NP_000296.2|dip:DIP-61136N|refseq:NP_001018171.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:9zE87aut0R8eYxaXM+HgYsJxLYI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q15043	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952|ensembl:ENSP00000370635	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:XP_011542780.1|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_016868783.1|refseq:XP_016868784.1|ensembl:ENSG00000104635(gene)|ensembl:ENST00000289952(transcript)|ensembl:ENST00000381237(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015296"("anion:cation symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033212"(iron import into cell)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055071"(manganese ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0098739"(import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|mint:Q15043|reactome:R-HSA-442380	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14974	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14739	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14571	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2831342|uniprotkb:O94773|ensembl:ENSP00000370744	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:itpr2_human(display_long)|uniprotkb:ITPR2(gene name)|psi-mi:ITPR2(display_short)|uniprotkb:IP3 receptor isoform 2(gene name synonym)|uniprotkb:Type 2 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000123104(gene)|ensembl:ENST00000381340(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_002214.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:godRDJb6vyJG454Heg9JZhLarLc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14435	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-10697820|uniprotkb:Q7Z476|uniprotkb:Q53TG9|ensembl:ENSP00000376465	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:galt3_human(display_long)|uniprotkb:GALNT3(gene name)|psi-mi:GALNT3(display_short)|uniprotkb:Polypeptide GalNAc transferase 3(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 3(gene name synonym)|uniprotkb:"UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004473.2|refseq:XP_005246506.1|refseq:XP_011509231.1|ensembl:ENSG00000115339(gene)|ensembl:ENST00000392701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004653"(polypeptide N-acetylgalactosaminyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0018243"(protein O-linked glycosylation via threonine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|reactome:R-HSA-190372|reactome:R-HSA-5083625|reactome:R-HSA-913709|refseq:XP_016859259.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ctuWH3RUp0sYoXZl0G0gyZoQ8609606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14257	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q14165	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1046466|ensembl:ENSP00000228506	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q13885	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	intact:EBI-20649665	intact:EBI-21259559|ensembl:ENSP00000445773	-	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tuba3c_tuba3d_human(display_short)|psi-mi:EBI-20649665(display_long)|intact:TUBA3C/TUBA3D(author assigned name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	uniprotkb:P0DPH7(set member)|uniprotkb:P0DPH8(set member)|uniprotkb:Q13748(see-also)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q13617	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q13576	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q13144	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q13015	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-6269719|ensembl:ENSP00000357917	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q12797	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P78527	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P62306	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P62304	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P62258	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P60468	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P57678	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P56385	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P56182	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P55084	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P55072	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P54709	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P53621	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P53618	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P52789	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-741469|uniprotkb:Q8WU87|uniprotkb:Q9UN82|ensembl:ENSP00000290573|uniprotkb:D6W5J2	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hxk2_human(display_long)|uniprotkb:Hexokinase type II(gene name synonym)|uniprotkb:Muscle form hexokinase(gene name synonym)|uniprotkb:HK2(gene name)|psi-mi:HK2(display_short)|uniprotkb:Hexokinase-B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P52789|rcsb pdb:2NZT|rcsb pdb:5HEX|rcsb pdb:5HFU|rcsb pdb:5HG1|reactome:R-HSA-70171|go:"GO:0008865"(fructokinase activity)|ensembl:ENSG00000159399(gene)|ensembl:ENST00000290573(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|refseq:NP_000180.2|dip:DIP-50110N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:99w5KbKmsqMoorQz/wot6z6t2WM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P52701	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P52429	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P51648	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P51617	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P50402	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P49755	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P48444	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P48047	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P46977	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P40939	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P40855	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P39880	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P35606	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P33993	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P33527	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3911547|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4|ensembl:ENSP00000382342|ensembl:ENSP00000483316	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:"Leukotriene C(4) transporter"(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004987.2|ensembl:ENSG00000103222(gene)|ensembl:ENSG00000278183(gene)|ensembl:ENST00000399410(transcript)|ensembl:ENST00000621144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015420"(ABC-type vitamin B12 transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034040"(ATPase-coupled lipid transmembrane transporter activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0034775"(glutathione transmembrane transport)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0099039"(sphingolipid translocation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0140359"(ABC-type transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905039"(carboxylic acid transmembrane transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292("Multi drug resistance-associated protein (MRP)")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-196741|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-189483	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P30049	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P27824	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P27708	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P25705	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P24539	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P20674	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P20020	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P19367	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-713162|uniprotkb:Q5VTC3|uniprotkb:Q96HC8|uniprotkb:Q9NNZ4|uniprotkb:O43443|uniprotkb:O43444|uniprotkb:O75574|uniprotkb:Q9NNZ5|uniprotkb:E9PCK0|ensembl:ENSP00000352398	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hxk1_human(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:HK1(gene name)|psi-mi:HK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000179.2|refseq:NP_277031.1|refseq:NP_277032.1|refseq:NP_277033.1|refseq:NP_277035.2|refseq:XP_011538034.1|refseq:NP_001309293.1|dip:DIP-56245N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P19367|rcsb pdb:1CZA|rcsb pdb:1DGK|rcsb pdb:1HKB|rcsb pdb:1HKC|rcsb pdb:1QHA|rcsb pdb:4FOE|rcsb pdb:4FOI|rcsb pdb:4FPA|rcsb pdb:4FPB|reactome:R-HSA-5619056|reactome:R-HSA-70171|rcsb pdb:4F9O|ensembl:ENSG00000156515(gene)|ensembl:ENST00000359426(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:cvNEGlnCikx3E17kNYTSI39EUfU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P18859	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P18031	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-968788|ensembl:ENSP00000360683|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000196396(gene)|ensembl:ENST00000371621(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097443"(sorting endosome)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1AAX|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2NT7|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2NTA|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2QBP|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2QBS|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2VEU|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2F6Z|rcsb pdb:2ZMM|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:6OMY|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:3EB1|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:7KEN|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MM1|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|rcsb pdb:6PFW|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QDV|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P17509	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-741308|ensembl:ENSP00000225648|ensembl:ENSP00000420009|uniprotkb:P09068|uniprotkb:Q9HB11|uniprotkb:Q9UGH2|uniprotkb:A8K835|uniprotkb:D3DTV5	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hxb6_human(display_long)|uniprotkb:Homeobox protein Hox-2B(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein Hu-2(gene name synonym)|uniprotkb:HOXB6(gene name)|psi-mi:HOXB6(display_short)|uniprotkb:HOX2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P17509|ensembl:ENSG00000108511(gene)|ensembl:ENST00000225648(transcript)|ensembl:ENST00000484302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_061825.2|refseq:XP_005257340.1|refseq:XP_005257341.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:5MTUEA03jhudRW4zALviuhMFPPc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P17302	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P16615	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P13073	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P12277	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P12236	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P07858	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P06576	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P05026	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P05023	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P04843	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P04350	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P04181	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-721662|uniprotkb:Q68CS0|uniprotkb:Q16068|uniprotkb:Q16069|uniprotkb:Q9UD03|intact:EBI-1237002|uniprotkb:Q6IAV9|uniprotkb:D3DRF0|ensembl:ENSP00000357838	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:oat_human(display_long)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym)|uniprotkb:OAT(gene name)|psi-mi:OAT(display_short)|uniprotkb:Ornithine delta-aminotransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000265.1|refseq:NP_001165285.1|refseq:NP_001309894.1|refseq:NP_001309895.1|refseq:NP_001309896.1|refseq:NP_001309897.1|refseq:NP_001309898.1|refseq:NP_001309899.1|refseq:NP_001309900.1|rcsb pdb:6OIA|rcsb pdb:6V8C|rcsb pdb:6V8D|rcsb pdb:7JX9|reactome:R-HSA-8964539|ensembl:ENSG00000065154(gene)|ensembl:ENST00000368845(transcript)|go:"GO:0004587"(ornithine-oxo-acid transaminase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007601"(visual perception)|go:"GO:0010121"(arginine catabolic process to proline via ornithine)|go:"GO:0019544"(arginine catabolic process to glutamate)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050155"("ornithine(lysine) transaminase activity")|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1GBN|rcsb pdb:1OAT|rcsb pdb:2BYJ|rcsb pdb:2BYL|rcsb pdb:2CAN|rcsb pdb:2OAT|rcsb pdb:5VWO|rcsb pdb:6HX7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:j+e5fOgz5Yv7lLp2NV8Uq+eR6909606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P04075	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P04035	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:P03928	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:YP_003024030.1|ensembl:ENSG00000228253(gene)|ensembl:ENST00000361851(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O95831	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O95793	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O95470	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O94905	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O94829	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O94822	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O76071	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O75964	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O75947	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O75477	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O75396	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O75155	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O43819	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O43592	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15397	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15355	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15270	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15269	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15260	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O15120	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3935937|uniprotkb:Q9BWR7|uniprotkb:O00516|uniprotkb:Q5VUD4|uniprotkb:Q9BSV7|uniprotkb:O15106|uniprotkb:Q5VUD3|intact:EBI-28988552|ensembl:ENSP00000360761|ensembl:ENSP00000438919	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:plcb_human(display_long)|uniprotkb:AGPAT2(gene name)|psi-mi:AGPAT2(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 2(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001012745.1|refseq:NP_006403.2|ensembl:ENST00000371694|ensembl:ENSP00000360759|ensembl:ENSP00000360761|ensembl:ENSP00000438919|ensembl:ENSG00000169692(gene)|ensembl:ENST00000371696(transcript)|ensembl:ENST00000538402(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:quJFJpDvkJbjDx+PiTqRDpLfqzg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14980	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14975	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14967	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14681	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-2339413|uniprotkb:Q9BUQ1|uniprotkb:A8K7D6|uniprotkb:B4DKL6|ensembl:ENSP00000278903|ensembl:ENSP00000484510	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ei24_human(display_long)|uniprotkb:EI24(gene name)|psi-mi:EI24(display_short)|uniprotkb:PIG8(gene name synonym)|uniprotkb:p53-induced gene 8 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:XP_011541371.1|refseq:NP_001277064.1|refseq:NP_004870.3|ensembl:ENSG00000149547(gene)|ensembl:ENST00000278903(transcript)|ensembl:ENST00000620753(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR009890(Etoposide-induced 2.4)|mint:O14681	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:mb5BoJ3ithOKYe8mN+ZRB4UoltI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14672	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1536151|uniprotkb:Q10742|uniprotkb:Q92650|uniprotkb:B4DU28|ensembl:ENSP00000260408	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ada10_human(display_long)|uniprotkb:ADAM10(gene name)|psi-mi:ADAM10(display_short)|uniprotkb:KUZ(gene name synonym)|uniprotkb:MADM(gene name synonym)|uniprotkb:Mammalian disintegrin-metalloprotease(gene name synonym)|uniprotkb:Kuzbanian protein homolog(gene name synonym)|uniprotkb:CDw156(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001101.1|dip:DIP-39889N|ensembl:ENSG00000137845(gene)|ensembl:ENST00000260408(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042117"(monocyte activation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0051089"(constitutive protein ectodomain proteolysis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090102"(cochlea development)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1901342"(regulation of vasculature development)|go:"GO:1901998"(toxin transport)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR024079|interpro:IPR027053|interpro:IPR034025|interpro:IPR036436|mint:O14672|rcsb pdb:1M1I|rcsb pdb:6BDZ|rcsb pdb:6BE6|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-177929|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-977225	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:oaWIe6XWClYEFZKUARbeLsWRsu49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14654	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14617	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_003929.4|refseq:NP_001248755.1|ensembl:ENSG00000065000(gene)|ensembl:ENST00000345016(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|dip:DIP-46793N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O14579	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O00743	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O00264	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:O00165	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:M0QZX5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21261668|ensembl:ENSP00000470834	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:m0qzx5_human(display_long)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000105135(gene)|ensembl:ENST00000598709(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR029035	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hXycrRCQFMdvAFb4dmK4T7Z6NM89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:H3BV16	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21264870|ensembl:ENSP00000457908	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:h3bv16_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000140990(gene)|ensembl:ENST00000570172(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0070469"(respirasome)|interpro:IPR019377|interpro:IPR039993	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:/sfTdLokctzOx6u8xrN2rqwkslk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:H0YIN8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262854|ensembl:ENSP00000449781	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:h0yin8_human(display_long)|uniprotkb:ANKRD13A(gene name)|psi-mi:ANKRD13A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000076513(gene)|ensembl:ENST00000547639(transcript)|go:"GO:0016020"(membrane)|interpro:IPR021832	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:4MpnX/lh3esDOFKvYs3ow3Rs/jc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:Q9NVI7-3	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-25339540|ensembl:ENSP00000439290	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:q9nvi7-3(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000197785(gene)|ensembl:ENST00000536055(transcript)|intact:EBI-352007(isoform-parent)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:fJvDRPIoHc84N+Kxf2shkOo1qB09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:E7EPB3	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21264855|ensembl:ENSP00000391446	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:e7epb3_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000188846(gene)|ensembl:ENST00000416518(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR039660|interpro:IPR041985	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:INjqgtDGHHmR14PAmHVezlKncoE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:E1NZA1	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21258417	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:C9JW96	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21258889|ensembl:ENSP00000393320	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:c9jw96_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000167085(gene)|ensembl:ENST00000419140(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:m+QS9IeeD5UlWLw8/X1LBNGUqMQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:C9JU30	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21262814|ensembl:ENSP00000419516	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:c9ju30_human(display_long)|uniprotkb:ST7(gene name)|psi-mi:ST7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENST00000490039(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007311(ST7)|ensembl:ENSG00000004866(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Rm7BdWrtmoIXb94+d4CFmnlv43w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:C9JU26	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:C9JI87	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21258875|ensembl:ENSP00000390129	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:c9ji87_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSG00000213585(gene)|ensembl:ENST00000425992(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:XQBT9gfVRbapMMX65dSqFGkk7p09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:B7ZM73	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21260321	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:B7ZAQ6	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-11288340|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:B4DLT3|uniprotkb:B4DXE7|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302|ensembl:ENSP00000319673	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:gphra_human(display_long)|uniprotkb:GPR89A(gene name)|psi-mi:GPR89A(display_short)|uniprotkb:GPHRA(gene name synonym)|uniprotkb:GPR89(gene name synonym)|uniprotkb:Protein GPR89A(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM01(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 90(gene name synonym)|uniprotkb:SH120(gene name synonym)|uniprotkb:CGI-13(orf name)|uniprotkb:UNQ192/PRO218(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	refseq:NP_001091081.1|refseq:NP_001091082.2|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_005277459.1|refseq:XP_005277461.1|refseq:XP_006711440.1|refseq:XP_006711441.1|refseq:XP_006711555.1|refseq:XP_006711556.1|refseq:XP_011507912.1|refseq:XP_011507914.1|refseq:XP_011508210.1|refseq:XP_011508211.1|refseq:XP_016856937.1|ensembl:ENSG00000117262(gene)|ensembl:ENST00000313835(transcript)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051452"(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:B2RWN5	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-21258368	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F5H1C8	uniprotkb:A0FGR8	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21264930|imex:IM-26691-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9Y5V3	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9Y5A9	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918|ensembl:ENSP00000444660	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492(gene)|ensembl:ENST00000373812(transcript)|ensembl:ENST00000542507(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|mint:Q9Y5A9|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:4RDN	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9Y234	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-727376|uniprotkb:Q4ZFZ1|ensembl:ENSP00000377114|ensembl:ENSP00000377115|ensembl:ENSP00000498546	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:lipt_human(display_long)|uniprotkb:Lipoate-protein ligase(gene name synonym)|uniprotkb:Lipoate biosynthesis protein(gene name synonym)|uniprotkb:Lipoyl ligase(gene name synonym)|uniprotkb:LIPT1(gene name)|psi-mi:LIPT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001191759.1|refseq:NP_057013.1|refseq:NP_660198.1|refseq:NP_660199.1|refseq:NP_660200.1|ensembl:ENSG00000144182(gene)|ensembl:ENST00000393471(transcript)|ensembl:ENST00000393473(transcript)|ensembl:ENST00000651691(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017118"(lipoyltransferase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR004143(Biotin/lipoate A/B protein ligase)|interpro:IPR004562(Lipoyltransferase and lipoate-protein ligase)|reactome:R-HSA-389661	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:OKGFro3bW4qrpHml2H4CtrdGgfc9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9UP83	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-389502|uniprotkb:A4D0R6|uniprotkb:A4D0R7|uniprotkb:Q6NUL5|uniprotkb:O14555|uniprotkb:O95008|ensembl:ENSP00000297135|ensembl:ENSP00000334703|ensembl:ENSP00000377228	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:cog5_human(display_long)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001154992.1|refseq:NP_006339.3|refseq:NP_859422.2|ensembl:ENSG00000164597(gene)|ensembl:ENST00000297135(transcript)|ensembl:ENST00000347053(transcript)|ensembl:ENST00000393603(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR019465|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:Jytff1Ttr5vNSps1MeFz2ZoP1Kg9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9UI12	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q9H078	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q96T76	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q96AQ6	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q92947	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q8TCG1	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:Q15758	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P54709	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P31930	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P30837	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1237410|uniprotkb:Q8WX76|uniprotkb:Q9BV45|uniprotkb:B2R8F0|ensembl:ENSP00000366927	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:al1b1_human(display_long)|uniprotkb:ALDH1B1(gene name)|psi-mi:ALDH1B1(display_short)|uniprotkb:ALDH5(gene name synonym)|uniprotkb:ALDHX(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member B1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_000683.3|ensembl:ENSG00000137124(gene)|ensembl:ENST00000377698(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P30837|reactome:R-HSA-71384|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:esHIXlANuM3Gmcr8ldyTq/nAyUM9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P22695	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P10809	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:P05023	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:O60762	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:O15269	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:O00165	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:K7EPH2	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-21265607|ensembl:ENSP00000467384	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:k7eph2_human(display_long)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040724|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|ensembl:ENSG00000179115(gene)|ensembl:ENST00000593021(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:X5DlFN6NTBke2ilf9kE3e3ofvRQ9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:H0YL12	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-21259817|ensembl:ENSP00000453017	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:h0yl12_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	go:"GO:0005759"(mitochondrial matrix)|ensembl:ENSG00000140374(gene)|ensembl:ENST00000560345(transcript)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR029035|interpro:IPR033947	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:Cw4dRHI2p2B3Ge4EJBFj2UT9b2Q9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:C9J3R0	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-21260334|ensembl:ENSP00000405258	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:c9j3r0_human(display_long)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	ensembl:ENSG00000180198(gene)|ensembl:ENST00000434290(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:9+fGe4T/zhgH2VO1XOSM5OqXdEw9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:X6RFA8	uniprotkb:C9J2P2	intact:EBI-21265595|ensembl:ENSP00000399102	intact:EBI-21262793|ensembl:ENSP00000410643	psi-mi:x6rfa8_human(display_long)|uniprotkb:SLC25A28(gene name)|psi-mi:SLC25A28(display_short)	psi-mi:c9j2p2_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265624|imex:IM-26691-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155287(gene)|ensembl:ENST00000434701(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018108|interpro:IPR023395	ensembl:ENSG00000105993(gene)|ensembl:ENST00000441561(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:biQvy6QVs87pdG1evQB02lnNRUk9606	rogid:PI3kVGcOb+bwk/QBRF7sQDXJvow9606	rigid:VY+SGipCGrw04aeD8tX3Mhzmba0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q93034	uniprotkb:O14508	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	intact:EBI-617737|ensembl:ENSP00000339428|ensembl:ENSP00000442898|ensembl:ENSP00000447161|ensembl:ENSP00000448815|ensembl:ENSP00000449227|ensembl:ENSP00000481249|uniprotkb:O14542|uniprotkb:O95102|uniprotkb:Q9UKS5|uniprotkb:A8K3D1	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:socs2_human(display_long)|uniprotkb:Cytokine-inducible SH2 protein 2(gene name synonym)|uniprotkb:STAT-induced STAT inhibitor 2(gene name synonym)|uniprotkb:CIS2(gene name synonym)|uniprotkb:SSI2(gene name synonym)|uniprotkb:STATI2(gene name synonym)|uniprotkb:SOCS2(gene name)|psi-mi:SOCS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265702|imex:IM-26691-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N	ensembl:ENSG00000120833(gene)|ensembl:ENST00000340600(transcript)|ensembl:ENST00000536696(transcript)|ensembl:ENST00000549122(transcript)|ensembl:ENST00000551556(transcript)|ensembl:ENST00000622746(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007595"(lactation)|go:"GO:0008269"(JAK pathway signal transduction adaptor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060749"(mammary gland alveolus development)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028410|interpro:IPR035862|interpro:IPR036036|interpro:IPR036860|mint:O14508|ensembl:ENST00000549206(transcript)|rcsb pdb:2C9W|rcsb pdb:4JGH|rcsb pdb:5BO4|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|reactome:R-HSA-1266695|reactome:R-HSA-8951664|reactome:R-HSA-9706369|reactome:R-HSA-982772|refseq:NP_003868.1|refseq:NP_001257396.1|refseq:NP_001257397.1|refseq:NP_001257398.1|refseq:NP_001257399.1|refseq:NP_001257400.1|refseq:XP_016875645.1|dip:DIP-29569N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	rogid:vh/FSp+KisXm9YDUkf26UU7ucgI9606	rigid:PvMj0/TIAWrZFNpKJLsE9VVm2nw	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P25800	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-8639312|ensembl:ENSP00000338207|intact:MINT-8162911|uniprotkb:Q4VBC5|uniprotkb:Q8IXR0|uniprotkb:E9PSF5	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:rbtn1_human(display_long)|uniprotkb:LMO1(gene name)|psi-mi:LMO1(display_short)|uniprotkb:Cysteine-rich protein TTG-1(gene name synonym)|uniprotkb:LIM domain only protein 1(gene name synonym)|uniprotkb:RBTN1(gene name synonym)|uniprotkb:RHOM1(gene name synonym)|uniprotkb:T-cell translocation protein 1(gene name synonym)|uniprotkb:TTG1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	ensembl:ENSG00000166407(gene)|ensembl:ENST00000335790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046013"(regulation of T cell homeostatic proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-HSA-8939236|refseq:NP_001257357.1|refseq:NP_002306.1	-	crc64:DBBB169D4EE10536	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:VN6uHPF606TKkAnFCui/Pe1LkwA9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:U3KQ46	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-21265711|ensembl:ENSP00000475538	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:u3kq46_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	ensembl:ENSG00000130511(gene)|ensembl:ENST00000597724(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:Is2JhMvXDy5Qzvmu70TF0+IuSlw9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q9H0D6	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q96A47	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-18560216|uniprotkb:B3KM37|ensembl:ENSP00000290759	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:isl2_human(display_long)|uniprotkb:ISL2(gene name)|psi-mi:ISL2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_665804.1|ensembl:ENSG00000159556(gene)|ensembl:ENST00000290759(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048666"(neuron development)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q96A47|go:"GO:0045665"(negative regulation of neuron differentiation)	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:TuRrmmyJy7Dk+0fn1BDmkcmUf1A9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q969G2	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553	-	crc64:DBBB169D4EE10536	crc64:6499F38E78B79FD1	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q8NC56	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q86U70	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:Q04837	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P81877	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P61968	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N	-	crc64:DBBB169D4EE10536	crc64:C8AC295144AD7787	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P42166	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P39880	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P18887	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:P06703	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-352877|ensembl:ENSP00000357708|ensembl:ENSP00000357709|ensembl:ENSP00000473589|uniprotkb:Q5RHS4|uniprotkb:D3DV39	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:s10a6_human(display_long)|uniprotkb:S100A6(gene name)|psi-mi:S100A6(display_short)|uniprotkb:CACY(gene name synonym)|uniprotkb:S100 calcium-binding protein A6(gene name synonym)|uniprotkb:Calcyclin(gene name synonym)|uniprotkb:Prolactin receptor-associated protein(gene name synonym)|uniprotkb:Growth factor-inducible protein 2A9(gene name synonym)|uniprotkb:MLN 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	ensembl:ENSG00000197956(gene)|ensembl:ENST00000368719(transcript)|ensembl:ENST00000368720(transcript)|ensembl:ENST00000496817(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034118|mint:P06703|rcsb pdb:1K8U|rcsb pdb:1K96|rcsb pdb:1K9K|rcsb pdb:1K9P|rcsb pdb:2M1K|rcsb pdb:4YBH|go:"GO:0062023"(collagen-containing extracellular matrix)|refseq:NP_055439.1|refseq:XP_016857522.1	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:y8rq2lO1c3DEoVaKnfoLEAHsqmo9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:O75531	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:O60663	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-296386|uniprotkb:O75463|uniprotkb:Q5JU95|uniprotkb:Q6ISC9|ensembl:ENSP00000362573|uniprotkb:F8W7W6	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:lmx1b_human(display_long)|uniprotkb:LMX1B(gene name)|psi-mi:LMX1B(display_short)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000136944(gene)|ensembl:ENST00000373474(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001701"(in utero embryonic development)|refseq:NP_001167618.1|refseq:NP_002307.2	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:ERk5ljL48TxeUJQiYNxmIRYKNI89606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BWW4	uniprotkb:H7C0H1	intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674	intact:EBI-21260200|ensembl:ENSP00000394978	psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)	psi-mi:h7c0h1_human(display_long)|uniprotkb:LHX2(gene name)|psi-mi:LHX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265722|imex:IM-26691-131	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4	ensembl:ENSG00000106689(gene)|ensembl:ENST00000446480(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970	-	crc64:DBBB169D4EE10536	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606	rogid:MgM62/yz2WSLsuEzx9vfaBHyjx09606	rigid:nB1sWxdmpVok7uMp3LCT2RQ2RR0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P33316	uniprotkb:P40763	intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265779|imex:IM-26691-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	-	-	crc64:6C00632211C8012D	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	rigid:sob5NhqVN/zyOau91g9+nwmVAjw	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q9Y297	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q9UET6	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1055987|uniprotkb:O75670|uniprotkb:B2RCJ0|ensembl:ENSP00000326948	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:trm7_human(display_long)|uniprotkb:FTSJ1(gene name)|psi-mi:FTSJ1(display_short)|uniprotkb:JM23(orf name)|uniprotkb:Protein ftsJ homolog 1(gene name synonym)|uniprotkb:2'-O-ribose RNA methyltransferase TRM7 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_036412.1|refseq:NP_803188.1|refseq:NP_001269086.1|refseq:XP_005272652.1|ensembl:ENST00000348411(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0002128"(tRNA nucleoside ribose methylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0009020"("tRNA (guanosine-2'-O-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0052666"("tRNA (cytosine-2'-O-)-methyltransferase activity")|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR028590|interpro:IPR029063|mint:Q9UET6|reactome:R-HSA-6782315|ensembl:ENSG00000068438(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:N4L9nsU0Wj3FMVjYALdxpx56aZs9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q9NNW5	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q96Q15	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:u7doCYezlcCUKq//xhk0TZ2TD009606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q96PK6	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q8WXH0	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q6P5S8	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-6677662	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:q6p5s8_human(display_long)|uniprotkb:IGK@(gene name)|psi-mi:IGK@(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	rcsb pdb:2NXZ|rcsb pdb:2NY0|rcsb pdb:2NY2|rcsb pdb:2NY4|rcsb pdb:2NY5|rcsb pdb:2NY3|go:"GO:0016020"(membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:2NXY|rcsb pdb:2NY1|rcsb pdb:2NY6|interpro:IPR036179	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:QB5zWAe8CmRCxpvKVhbH7O6h56w9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q6NZY4	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q13616	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:Q04446	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-726347|uniprotkb:Q96EN0|uniprotkb:B3KWV3|ensembl:ENSP00000410833	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:glgb_human(display_long)|uniprotkb:Glycogen-branching enzyme(gene name synonym)|uniprotkb:Brancher enzyme(gene name synonym)|uniprotkb:GBE1(gene name)|psi-mi:GBE1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_000149.3|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043169"(cation binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102752"("1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)")|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR037439|mint:Q04446|rcsb pdb:4BZY|rcsb pdb:5CLT|rcsb pdb:5CLW|reactome:R-HSA-3322077|reactome:R-HSA-3878781|ensembl:ENSG00000114480(gene)|ensembl:ENST00000429644(transcript)|go:"GO:0003844"(1,4-alpha-glucan branching enzyme activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:IEK9nw/2Vz9rVLyPSLTKC7neim09606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:P63208	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:P50402	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:P31946	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:P30049	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:O95470	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:J3KTF8	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-21265788|ensembl:ENSP00000462960	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:j3ktf8_human(display_long)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	ensembl:ENSG00000141522(gene)|ensembl:ENST00000579121(transcript)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:FLmOmCMGJLPLHc6ZwsOTrZklhtM9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UH99	uniprotkb:B4DH70	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	intact:EBI-12503567	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:b4dh70_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265800|imex:IM-26691-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|refseq:XP_005265915.1|refseq:XP_016864769.1|interpro:IPR036047|interpro:IPR036322	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rogid:ugaxcsBEMZbZZiiBcCJC1iyGnUw9606	rigid:ZRR40aZ27HotO5Um3Sx1a9E226w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:X5CMH5	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-21262914|ensembl:ENSP00000393580|ensembl:ENSP00000406540|ensembl:ENSP00000416471	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:x5cmh5_human(display_long)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	ensembl:ENSG00000223481(gene)|ensembl:ENSG00000225967(gene)|ensembl:ENSG00000232326(gene)|ensembl:ENST00000452371(transcript)|ensembl:ENST00000455842(transcript)|ensembl:ENST00000457634(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0042287"(MHC protein binding)|go:"GO:0042825"(TAP complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|refseq:NP_000535.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:c5RxmRf2D24+XCfzlzKnDvh80fM9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:Q5JSD2	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:P50402	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:P30101	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:P27824	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:P16615	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:O96008	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:O43169	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:I3L4P8	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q03518	uniprotkb:G3V234	intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660	intact:EBI-21265856|ensembl:ENSP00000450435	psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym)	psi-mi:g3v234_human(display_long)|uniprotkb:RDH11(gene name)|psi-mi:RDH11(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265865|imex:IM-26691-93	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N	ensembl:ENSG00000072042(gene)|ensembl:ENST00000557726(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036291|interpro:IPR002347(Glucose/ribitol dehydrogenase)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/05/28	rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606	rogid:DVvvKYAGleNHCRjbG0MHT3izCKY9606	rigid:SEHcvpkjrVPps0mmxJr3s9sk6+4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q14676	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35250	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35244	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P27694	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P15927	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q5SRQ6	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-7903168|intact:UNK-5448745|uniprotkb:Q5SQ53|ensembl:ENSP00000365046|ensembl:ENSP00000382984|ensembl:ENSP00000395546|ensembl:ENSP00000396772|ensembl:ENSP00000410942|ensembl:ENSP00000413092|ensembl:ENSP00000415615	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:q5srq6_human(display_long)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:hCG_43725(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000204435(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENST00000375885(transcript)|ensembl:ENST00000400116(transcript)|ensembl:ENST00000422261(transcript)|ensembl:ENST00000424502(transcript)|ensembl:ENST00000428483(transcript)|ensembl:ENST00000432290(transcript)|ensembl:ENST00000439572(transcript)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0019887"(protein kinase regulator activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:Q5SRQ6	-	-	comment:mint|comment:homomint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:3LnbiNSiy2J1rM1AhYU8qbOpq7c9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P42702	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-7702162|ensembl:ENSP00000263409|ensembl:ENSP00000398368|uniprotkb:Q6LCD9|intact:MINT-1352123	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:lifr_human(display_long)|uniprotkb:LIFR(gene name)|psi-mi:LIFR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:XP_016864952.1|ensembl:ENSG00000113594(gene)|ensembl:ENST00000263409(transcript)|ensembl:ENST00000453190(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040817|interpro:IPR040901|rcsb pdb:3E0G|reactome:R-HSA-6788467|reactome:R-HSA-8939247|refseq:XP_011512342.1|refseq:XP_011512344.1|refseq:NP_001121143.1|refseq:NP_002301.1|dip:DIP-5770N	-	-	comment:mint|function:Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells|function:"Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS) [MIM:601559]; also called Schwartz-Jampel syndrome type 2 or SJS2. SWS is a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias. SWS is characterized by bowing of the lower limbs, with internal cortical thickening, wide metaphyses with abnormal trabecular pattern, and camptodactyly. Additional features include feeding and swallowing difficulties, as well as respiratory distress and hyperthermic episodes, which cause death in the first months of life. The rare survivors develop progressive scoliosis, spontaneous fractures, bowing of the lower limbs, with prominent joints and dysautonomia symptoms, including temperature instability, absent corneal and patellar reflexes, and smooth tongue"|function:"A chromosomal rearrangement involving LIFR may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(5;8)(p13;q12) with PLAG1"	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:kteW2gF4cZU5b5JOkszDFWsgyN89606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:V9GYJ9	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21258097|ensembl:ENSP00000476840	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:v9gyj9_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000132676(gene)|ensembl:ENST00000497826(transcript)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:50eG8EdAwI2qgx55nzBr77AZ4mg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y6J0	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2795712|uniprotkb:Q9Y460|uniprotkb:G5E9F3|uniprotkb:Q6PHY0|intact:EBI-28988204|ensembl:ENSP00000263119|ensembl:ENSP00000381364	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:cabin_human(display_long)|uniprotkb:CABIN1(gene name)|psi-mi:CABIN1(display_short)|uniprotkb:KIAA0330(gene name synonym)|uniprotkb:Calcineurin inhibitor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001186210.1|refseq:NP_001188358.1|refseq:NP_036427.1|refseq:XP_016884172.1|ensembl:ENSP00000263119|ensembl:ENSP00000381364|ensembl:ENST00000405822|ensembl:ENSP00000384694|ensembl:ENSG00000099991(gene)|ensembl:ENST00000263119(transcript)|ensembl:ENST00000398319(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016235"(aggresome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015134(MEF2 binding)|interpro:IPR019734|interpro:IPR033053|mint:Q9Y6J0|rcsb pdb:1N6J|reactome:R-HSA-2559584	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:b4BLYv/aw7zl2SZQXLXAQr+RmY49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y5L4	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y5J9	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y5B9	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y3D5	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-5453854|ensembl:ENSP00000295491	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt18c_human(display_long)|uniprotkb:MRPS18C(gene name)|psi-mi:MRPS18C(display_short)|uniprotkb:28S ribosomal protein S18-1, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18c(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18m(gene name synonym)|uniprotkb:CGI-134(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001284698.1|refseq:NP_001284699.1|refseq:NP_057151.1|ensembl:ENSG00000163319(gene)|ensembl:ENST00000295491(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001648(Ribosomal protein S18)|interpro:IPR018275|interpro:IPR036870|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:WFVJqLIjMUdsPmYVjn7uvIxy+c49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y3D3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1049319|uniprotkb:Q96Q60|ensembl:ENSP00000362036|uniprotkb:B4E032	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt16_human(display_long)|uniprotkb:MRPS16(gene name)|psi-mi:MRPS16(display_short)|uniprotkb:RPMS16(gene name synonym)|uniprotkb:CGI-132(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS16m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_057149.1|ensembl:ENSG00000182180(gene)|ensembl:ENST00000372945(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|mint:Q9Y3D3|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|rcsb pdb:7A5F|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5G	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:jejigKZMzvzmWuhMXnBB3lNsShU9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y399	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y2R9	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y291	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2688704|ensembl:ENSP00000320567|ensembl:ENSP00000376732|ensembl:ENSP00000417287|ensembl:ENSP00000418451	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt33_human(display_long)|uniprotkb:MRPS33(gene name)|psi-mi:MRPS33(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS33(gene name synonym)|uniprotkb:CGI-139(orf name)|uniprotkb:PTD003(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_057155.1|refseq:NP_444263.1|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|ensembl:ENSG00000090263(gene)|ensembl:ENST00000324787(transcript)|ensembl:ENST00000393008(transcript)|ensembl:ENST00000469351(transcript)|ensembl:ENST00000496958(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR013219(Ribosomal protein S27, mitochondrial)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:lKeun672/ySI/pp5aA7KfONA2wM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9Y221	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-749003|uniprotkb:Q9NZZ0|uniprotkb:B2RD04|ensembl:ENSP00000254940	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:nip7_human(display_long)|uniprotkb:KD93(gene name synonym)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nucleolar pre-rRNA processing protein NIP7(gene name synonym)|uniprotkb:CGI-37(orf name)|uniprotkb:HSPC031(orf name)|uniprotkb:HSPC180(orf name)|uniprotkb:OK/SW-cl.76(orf name)|uniprotkb:OK/SW-cl.78(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001186363.1|refseq:NP_057185.1|ensembl:ENSG00000132603(gene)|ensembl:ENST00000254940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|mint:Q9Y221|rcsb pdb:1SQW|rcsb pdb:1T5Y|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:912ZyupB0CxH5w23chPh3IIICmY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9UPY3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9UNX4	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-727436|ensembl:ENSP00000308179	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_006775.1|ensembl:ENSG00000065183(gene)|ensembl:ENST00000349139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q9UNX4|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9UKD2	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9UGN5	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2795348|uniprotkb:Q8TEU4|uniprotkb:Q9NUV2|uniprotkb:Q9UMR4|uniprotkb:Q9Y6C8|ensembl:ENSP00000250416	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:parp2_human(display_long)|uniprotkb:PARP2(gene name)|psi-mi:PARP2(display_short)|uniprotkb:ADPRT2(gene name synonym)|uniprotkb:ADPRTL2(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 2"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 2(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 2(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP2(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001036083.1|refseq:NP_005475.2|ensembl:ENSG00000129484(gene)|ensembl:ENST00000250416(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016570"(histone modification)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036616|go:"GO:0005634"(nucleus)|interpro:IPR036930|mint:Q9UGN5|rcsb pdb:3KCZ|rcsb pdb:3KJD|rcsb pdb:4PJV|rcsb pdb:4TVJ|rcsb pdb:4ZZX|rcsb pdb:4ZZY|rcsb pdb:5D5K|rcsb pdb:5DSY|rcsb pdb:6F1K|rcsb pdb:6F5B|rcsb pdb:6F5F|rcsb pdb:6TX3|rcsb pdb:6USJ|rcsb pdb:6X0L|rcsb pdb:6X0M|rcsb pdb:6X0N|rcsb pdb:7AEO|reactome:R-HSA-110362|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|dip:DIP-48934N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:0sLs7K5dQNmmhUwnGT9UIvparjU9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9NX58	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q9NPG3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2880187|ensembl:ENSP00000262376|ensembl:ENSP00000379894|uniprotkb:B7Z6D3|uniprotkb:Q13079|uniprotkb:Q9P1P7|uniprotkb:D3DUE8	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ubn1_human(display_long)|uniprotkb:UBN1(gene name)|psi-mi:UBN1(display_short)|uniprotkb:HIRA-binding protein(gene name synonym)|uniprotkb:Protein VT4(gene name synonym)|uniprotkb:Ubiquitously expressed nuclear protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000118900(gene)|ensembl:ENST00000262376(transcript)|ensembl:ENST00000396658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026936|interpro:IPR026947|mint:Q9NPG3|rcsb pdb:4ZBJ|reactome:R-HSA-2559584|go:"GO:0005654"(nucleoplasm)|refseq:NP_001072982.1|refseq:XP_016878678.1|refseq:NP_001275585.1|ensembl:ENSP00000262376|ensembl:ENSP00000379894|ensembl:ENST00000590769|ensembl:ENSP00000468740	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:IT0lTmzNcbWFQVVD5DfATSqxjwg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q99714	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q96EY7	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q96CX2	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-358358|ensembl:ENSP00000366694	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q93009	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q92688	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q92665	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q92552	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q8NEV1	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21265922|ensembl:ENSP00000473553	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:csk23_human(display_long)|uniprotkb:CSNK2A3(gene name)|psi-mi:CSNK2A3(display_short)|uniprotkb:CSNK2A1P(gene name synonym)|uniprotkb:Casein kinase II alpha 1 polypeptide pseudogene(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0018105"(peptidyl-serine phosphorylation)|ensembl:ENSG00000254598(gene)|ensembl:ENST00000528848(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001243615.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:xTxpgfParbREfgLv/LUQQT1NSZw9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q8NC56	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q8IZL8	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:iu03DsintVoo3gWzZX14SlHE0ao9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q8IV63	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1058605|uniprotkb:Q502Y2|uniprotkb:Q9P2V8|uniprotkb:A8KA53|intact:EBI-1795523|uniprotkb:A6NEG5|ensembl:ENSP00000324636|ensembl:ENSP00000469880|ensembl:ENSP00000473171	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:vrk3_human(display_long)|uniprotkb:VRK3(gene name)|psi-mi:VRK3(display_short)|uniprotkb:Vaccinia-related kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001295349.1|refseq:NP_057524.3|refseq:NP_001020949.1|ensembl:ENSG00000105053(gene)|ensembl:ENST00000316763(transcript)|ensembl:ENST00000594948(transcript)|ensembl:ENST00000599538(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026870|rcsb pdb:2JII|reactome:R-HSA-202670|refseq:XP_005259028.1|refseq:XP_005259029.1|refseq:XP_006723300.1|refseq:XP_006723301.1|refseq:XP_011525325.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:eoBtIgSkVcOE5bw/By6UEqbiO/I9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q86UP2	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q7L0Y3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q6ZU65	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-9661773|uniprotkb:A4D1S2|uniprotkb:Q2YDY4|uniprotkb:Q6P1K0|uniprotkb:Q86XN9|uniprotkb:Q8N7D1|ensembl:ENSP00000418648	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ubn2_human(display_long)|uniprotkb:UBN2(gene name)|psi-mi:UBN2(display_short)|uniprotkb:KIAA2030(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSP00000418648|refseq:NP_775840.3|dip:DIP-47312N|ensembl:ENSG00000157741(gene)|ensembl:ENST00000473989(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026943|interpro:IPR026947|mint:Q6ZU65	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Z45kNtHT1rLdgqkCTrcRGD7L2749606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q3KQU3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-713229|uniprotkb:Q9HBQ2|uniprotkb:Q8N905|uniprotkb:Q9ULN3|uniprotkb:Q7L8J5|uniprotkb:Q8TAK0|intact:EBI-2511981|intact:EBI-1056140|ensembl:ENSP00000362244|uniprotkb:Q9NW29|uniprotkb:D3DPS4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ma7d1_human(display_long)|uniprotkb:MAP7D1(gene name)|psi-mi:MAP7D1(display_short)|uniprotkb:KIAA1187(gene name synonym)|uniprotkb:PARCC1(gene name synonym)|uniprotkb:RPRC1(gene name synonym)|uniprotkb:Proline/arginine-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Arginine/proline-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:PP2464(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001273294.1|refseq:NP_001273295.1|ensembl:ENSG00000116871(gene)|ensembl:ENST00000373151(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR008604(E-MAP-115)|mint:Q3KQU3|refseq:NP_060537.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:AEal3/uaJsdRBdmijI8nuthBD9k9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q16629	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-398885|uniprotkb:Q564D3|intact:EBI-11107979|uniprotkb:B4DLU6|uniprotkb:G5E9M3|ensembl:ENSP00000325905	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:srsf7_human(display_long)|uniprotkb:SRSF7(gene name)|psi-mi:SRSF7(display_short)|uniprotkb:Splicing factor 9G8(gene name synonym)|uniprotkb:SFRS7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001026854.1|refseq:NP_001182375.1|dip:DIP-31790N|ensembl:ENSG00000115875(gene)|ensembl:ENST00000313117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|mint:Q16629|rcsb pdb:2HVZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:12lFDvstcW/ySFKb4LR8KF9AylI9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q15185	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|refseq:NP_006592.3|dip:DIP-279N|ensembl:ENSG00000110958(gene)|ensembl:ENST00000262033(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043588"(skin development)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q15185|rcsb pdb:1EJF|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|rcsb pdb:1LG0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q14839	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q14527	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q13185	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q13162	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q09028	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q04837	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q03701	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:Q00610	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82933	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82932	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82930	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82921	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2372155|uniprotkb:Q9BST6|uniprotkb:A0A075B746|uniprotkb:Q5TB11|ensembl:ENSP00000461930|ensembl:ENSP00000480129	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt21_human(display_long)|uniprotkb:MRPS21(gene name)|psi-mi:MRPS21(display_short)|uniprotkb:RPMS21(gene name synonym)|uniprotkb:MDS016(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS21m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_061870.1|refseq:NP_114107.1|ensembl:ENSG00000266472(gene)|ensembl:ENST00000581066(transcript)|ensembl:ENST00000614145(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001911(Ribosomal protein S21)|interpro:IPR038380|mint:P82921|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:AGyHmum6PLo+BxY+wgQvG2894A49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82914	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82912	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2371859|uniprotkb:Q969D7|uniprotkb:Q96GI3|uniprotkb:Q9BYC3|uniprotkb:B2RD52|ensembl:ENSP00000317376	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt11_human(display_long)|uniprotkb:MRPS11(gene name)|psi-mi:MRPS11(display_short)|uniprotkb:RPMS11(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 2 protein(gene name synonym)|uniprotkb:HCC2(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS11m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001308899.1|refseq:NP_001308901.1|refseq:NP_001308902.1|refseq:NP_001308903.1|refseq:NP_001308905.1|refseq:NP_073750.2|refseq:NP_789775.1|ensembl:ENSG00000181991(gene)|ensembl:ENST00000325844(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P82912|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:aw3XzNBYY0igd4AUE1OQyfFn8pk9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82675	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82673	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82664	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1048271|uniprotkb:Q9H3E5|uniprotkb:Q9NVR3|uniprotkb:B2RE89|ensembl:ENSP00000053468	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt10_human(display_long)|uniprotkb:MRPS10(gene name)|psi-mi:MRPS10(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS10m(gene name synonym)|uniprotkb:MSTP040(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_060611.2|ensembl:ENSG00000048544(gene)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|ensembl:ENST00000053468(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR027486|interpro:IPR036838|interpro:IPR040055|mint:P82664|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|dip:DIP-50902N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:D6kypsC/rbFvPq5Y1YX9/DXtwtk9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P82650	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P78527	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P55084	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P54198	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P50402	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P49916	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1753381|intact:EBI-1058758|uniprotkb:Q16714|uniprotkb:Q6NVK3|ensembl:ENSP00000367787|uniprotkb:E5KLB5|uniprotkb:E5KLB6	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:dnli3_human(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_002302.2|refseq:NP_039269.2|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070421"(DNA ligase III-XRCC1 complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|mint:P49916|rcsb pdb:1IMO|rcsb pdb:1IN1|rcsb pdb:1UW0|rcsb pdb:3L2P|rcsb pdb:3PC7|rcsb pdb:3PC8|rcsb pdb:3QVG|rcsb pdb:6WH1|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006288"(base-excision repair, DNA ligation)|go:"GO:0006302"(double-strand break repair)|refseq:XP_016880113.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P46060	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P42167	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P42166	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P39880	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35659	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35610	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-6621955|ensembl:ENSP00000356591|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:"Acyl-coenzyme A:cholesterol acyltransferase 1"(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0010878"(cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0034736"(cholesterol O-acyltransferase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|ensembl:ENSG00000057252(gene)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|ensembl:ENST00000367619(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004772"(sterol O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010742"(macrophage derived foam cell differentiation)|refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35222	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P35221	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P34932	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P28370	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P26232	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-3953920|uniprotkb:B3KXE5|uniprotkb:B7Z2W7|uniprotkb:B7Z352|uniprotkb:B7Z898|uniprotkb:Q4ZFW1|uniprotkb:Q53R26|uniprotkb:Q53R33|uniprotkb:Q53T67|uniprotkb:Q53T71|uniprotkb:Q53TM8|uniprotkb:Q7Z3L1|uniprotkb:Q7Z3Y0|ensembl:ENSP00000384638	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ctna2_human(display_long)|uniprotkb:CTNNA2(gene name)|psi-mi:CTNNA2(display_short)|uniprotkb:CAPR(gene name synonym)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001269526.1|refseq:NP_001269527.1|refseq:NP_001269528.1|refseq:NP_001269529.1|refseq:XP_011530857.1|refseq:XP_011530858.1|refseq:NP_001158355.1|refseq:NP_004380.2|ensembl:ENSG00000066032(gene)|ensembl:ENST00000402739(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|rcsb pdb:6DUW|reactome:R-HSA-525793|go:"GO:0005829"(cytosol)|refseq:NP_001307739.1|refseq:XP_016858892.1|dip:DIP-60979N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Ms14mzGAhm356B/enTGIoPN5L5s9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P20226	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P17480	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-396235|uniprotkb:A8K6R8|ensembl:ENSP00000302640|ensembl:ENSP00000390669|ensembl:ENSP00000435708	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ubf1_human(display_long)|uniprotkb:UBTF(gene name)|psi-mi:UBTF(display_short)|uniprotkb:UBF(gene name synonym)|uniprotkb:UBF1(gene name synonym)|uniprotkb:Upstream-binding factor 1(gene name synonym)|uniprotkb:Autoantigen NOR-90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001070151.1|refseq:NP_001070152.1|refseq:NP_055048.1|refseq:XP_006722122.1|refseq:XP_006722123.1|refseq:XP_006722124.1|refseq:XP_016880492.1|refseq:XP_016880493.1|dip:DIP-640N|ensembl:ENSG00000108312(gene)|ensembl:ENST00000302904(transcript)|ensembl:ENST00000436088(transcript)|ensembl:ENST00000529383(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001165"(RNA polymerase I cis-regulatory region sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910|mint:P17480|rcsb pdb:1K99|rcsb pdb:1L8Y|rcsb pdb:1L8Z|rcsb pdb:2HDZ|reactome:R-HSA-427413|reactome:R-HSA-73728|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:uHwgY0OFREKv8MdMOMpREDgUEI89606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P14373	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P13010	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P12956	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P09874	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P09661	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P09496	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P09429	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:P07199	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-949451|intact:EBI-28970331|ensembl:ENSP00000369075|uniprotkb:Q96EI4	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:cenpb_human(display_long)|uniprotkb:Centromere protein B(gene name synonym)|uniprotkb:CENPB(gene name)|psi-mi:CENPB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSP00000369075|ensembl:ENSG00000125817(gene)|ensembl:ENST00000379751(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015115(Centromere protein B dimerisation)|interpro:IPR033062|interpro:IPR034882|mint:P07199|rcsb pdb:1BW6|rcsb pdb:1HLV|rcsb pdb:1UFI|rcsb pdb:6KDR|refseq:NP_001801.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:+03fJP9KYbjMxvL/JrO0Wj4+MJs9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O95757	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O94776	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O75607	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:lryH+qFG3/zmXWyn25dmU44prpk9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O75475	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1801773|uniprotkb:O00256|uniprotkb:O95368|uniprotkb:Q6P391|uniprotkb:Q86YB9|uniprotkb:Q9NZI3|uniprotkb:Q9UER6|uniprotkb:D3DRI9|ensembl:ENSP00000370109|ensembl:ENSP00000370114	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:psip1_human(display_long)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001304827.1|refseq:NP_001304829.1|refseq:NP_001121689.1|refseq:NP_066967.3|refseq:NP_150091.2|dip:DIP-46656N|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:O75475|rcsb pdb:1Z9E|rcsb pdb:2B4J|rcsb pdb:2M16|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2N3A|rcsb pdb:3F9K|rcsb pdb:3HPG|rcsb pdb:3HPH|rcsb pdb:3U88|rcsb pdb:3ZEH|rcsb pdb:4FU6|rcsb pdb:5N88|rcsb pdb:5OYM|rcsb pdb:5YI9|rcsb pdb:6EMO|rcsb pdb:6EMP|rcsb pdb:6EMQ|rcsb pdb:6EMR|rcsb pdb:6S01|rcsb pdb:6TRJ|rcsb pdb:6TVM|rcsb pdb:6Z2Y|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O75340	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O60664	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O60287	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1762349|uniprotkb:D3DSE5|uniprotkb:Q96NX1|uniprotkb:Q9NYQ1|ensembl:ENSP00000372199	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:npa1p_human(display_long)|uniprotkb:URB1(gene name)|psi-mi:URB1(display_short)|uniprotkb:C21orf108(gene name synonym)|uniprotkb:KIAA0539(gene name synonym)|uniprotkb:NPA1(gene name synonym)|uniprotkb:URB1 ribosome biogenesis 1 homolog(gene name synonym)|uniprotkb:NOP254(gene name synonym)|uniprotkb:Nucleolar protein 254 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_055640.2|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844|ensembl:ENSG00000142207(gene)|ensembl:ENST00000382751(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:tolq2rVG0N5qy3qGiIkPj8xtVis9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O60220	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O43395	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:O00541	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:I3L4Y2	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21265912|ensembl:ENSP00000461630	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:i3l4y2_human(display_long)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000103495(gene)|ensembl:ENST00000562557(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:hICmZ7e7XtjEbI/6GYKqa4qvpCU9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:H3BSA1	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21265901|ensembl:ENSP00000456606	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:h3bsa1_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000070770(gene)|ensembl:ENST00000567730(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:xkCOXZ++ZsvA1HIgyKe5qrqCCpo9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:H3BS86	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21259582|ensembl:ENSP00000456591	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:h3bs86_human(display_long)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	ensembl:ENSG00000103266(gene)|ensembl:ENST00000567173(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041312	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:kIb5YkvjJXhsREYdDvtNbuGPOdE9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:A5Y5A3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-21258050	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:a5y5a3_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	interpro:IPR019375|interpro:IPR007327(Tumor protein D52)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:E1eAJfa6apGwWt2MJ5pmGYaXZow9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NQB0	uniprotkb:A4D110	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-9978194	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:a4d110_human(display_long)|uniprotkb:LOC401309(gene name)|psi-mi:LOC401309(display_short)|uniprotkb:tcag7.949(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21265942|imex:IM-26691-117	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430	interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:RKxCH9JtTeX5LqThR82X/1ohRjM9606	rigid:XffBI41yJrwRfctGNMYkg9wZEks	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5JRV8	uniprotkb:Q92973	intact:EBI-21266247|ensembl:ENSP00000310110|uniprotkb:A8K0W9|uniprotkb:B1APR4|uniprotkb:B3KPI6|uniprotkb:E9PAR3|uniprotkb:Q86Y72|uniprotkb:Q9NWN8	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:t255a_human(display_long)|uniprotkb:TMEM255A(gene name)|psi-mi:TMEM255A(display_short)|uniprotkb:FAM70A(gene name synonym)|uniprotkb:Protein FAM70A(gene name synonym)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266273|imex:IM-26691-171	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125355(gene)|ensembl:ENST00000309720(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028014|refseq:NP_001098014.1|refseq:NP_001098015.1|refseq:NP_060408.3	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:efm3NQ+7op7AtbDZzxOzbTAa8eg9606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	rigid:XeDvfYuon1dhYggF3hxCkE8Z6IA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5JRV8	uniprotkb:Q8N5G2	intact:EBI-21266247|ensembl:ENSP00000310110|uniprotkb:A8K0W9|uniprotkb:B1APR4|uniprotkb:B3KPI6|uniprotkb:E9PAR3|uniprotkb:Q86Y72|uniprotkb:Q9NWN8	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463	psi-mi:t255a_human(display_long)|uniprotkb:TMEM255A(gene name)|psi-mi:TMEM255A(display_short)|uniprotkb:FAM70A(gene name synonym)|uniprotkb:Protein FAM70A(gene name synonym)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266273|imex:IM-26691-171	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125355(gene)|ensembl:ENST00000309720(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028014|refseq:NP_001098014.1|refseq:NP_001098015.1|refseq:NP_060408.3	refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:efm3NQ+7op7AtbDZzxOzbTAa8eg9606	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	rigid:XeDvfYuon1dhYggF3hxCkE8Z6IA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5JRV8	uniprotkb:P27824	intact:EBI-21266247|ensembl:ENSP00000310110|uniprotkb:A8K0W9|uniprotkb:B1APR4|uniprotkb:B3KPI6|uniprotkb:E9PAR3|uniprotkb:Q86Y72|uniprotkb:Q9NWN8	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:t255a_human(display_long)|uniprotkb:TMEM255A(gene name)|psi-mi:TMEM255A(display_short)|uniprotkb:FAM70A(gene name synonym)|uniprotkb:Protein FAM70A(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266273|imex:IM-26691-171	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125355(gene)|ensembl:ENST00000309720(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028014|refseq:NP_001098014.1|refseq:NP_001098015.1|refseq:NP_060408.3	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:efm3NQ+7op7AtbDZzxOzbTAa8eg9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:XeDvfYuon1dhYggF3hxCkE8Z6IA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q8IXI1	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9P2R7	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9P032	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9NSE4	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9H3G5	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9BXW7	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-4399500|uniprotkb:B2RCK5|uniprotkb:Q9BXW8|uniprotkb:Q9NWA8|uniprotkb:Q9NX41|ensembl:ENSP00000337358	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:hdhd5_human(display_long)|uniprotkb:HDHD5(gene name)|psi-mi:HDHD5(display_short)|uniprotkb:CECR5(gene name synonym)|uniprotkb:Cat eye syndrome critical region protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_060299.4|refseq:NP_149061.1|ensembl:ENSG00000069998(gene)|ensembl:ENST00000336737(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|interpro:IPR006353(HAD-superfamily hydrolase, subfamily IIA, CECR5)|interpro:IPR006357(HAD-superfamily hydrolase, subfamily IIA)|interpro:IPR023214|interpro:IPR029621|interpro:IPR036412|mint:Q9BXW7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:INkCPE3PGW5PVO8j4245B1F99HU9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q9BQA1	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:0q4wunYtHalObC8r1wphhelIpr49606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q96C36	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q969Z0	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q969S9	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2371750|uniprotkb:Q8WYI0|uniprotkb:A0AR28|uniprotkb:Q8N6D8|uniprotkb:Q9H6Z1|intact:EBI-28986334|ensembl:ENSP00000296805|ensembl:ENSP00000427004	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:rrf2m_human(display_long)|uniprotkb:GFM2(gene name)|psi-mi:GFM2(display_short)|uniprotkb:EFG2(gene name synonym)|uniprotkb:Elongation factor G 2, mitochondrial(gene name synonym)|uniprotkb:Elongation factor G2(gene name synonym)|uniprotkb:MSTP027(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_115756.2|refseq:NP_733781.1|refseq:NP_733792.1|ensembl:ENST00000345239|ensembl:ENSP00000296804|ensembl:ENST00000427854|ensembl:ENSP00000405808|ensembl:ENSP00000427004|ensembl:ENSP00000296805|refseq:NP_001268231.1|refseq:XP_016865475.1|dip:DIP-53437N|ensembl:ENSG00000164347(gene)|ensembl:ENST00000296805(transcript)|ensembl:ENST00000509430(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006414"(translational elongation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0070126"(mitochondrial translational termination)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR030851|interpro:IPR031157|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|mint:Q969S9|rcsb pdb:7L20|rcsb pdb:7NSH|reactome:R-HSA-5419276	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:tDdVCBcztI95aArJCyypUgUrWOw9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q8TB37	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-12852610|ensembl:ENSP00000281081|uniprotkb:B4DHZ1|uniprotkb:Q86TZ4|uniprotkb:Q9H9M2	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:nubpl_human(display_long)|uniprotkb:NUBPL(gene name)|psi-mi:NUBPL(display_short)|uniprotkb:C14orf127(gene name synonym)|uniprotkb:IND1 homolog(gene name synonym)|uniprotkb:Nucleotide-binding protein-like(gene name synonym)|uniprotkb:huInd1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000151413(gene)|ensembl:ENST00000281081(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR033756|interpro:IPR044304|reactome:R-HSA-6799198|refseq:NP_001188502.1|refseq:NP_079428.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:e9UiCfG76k75Df7cMDdOmi/LI7I9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q8NI60	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q8N1G4	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2509921|ensembl:ENSP00000367498|uniprotkb:Q9ULN5	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:lrc47_human(display_long)|uniprotkb:LRRC47(gene name)|psi-mi:LRRC47(display_short)|uniprotkb:KIAA1185(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000130764(gene)|ensembl:ENST00000378251(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR020825|interpro:IPR025875|interpro:IPR032675|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|refseq:NP_065761.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:aPzU//EIwK8J4it97jCw/YyKFWU9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q6UB35	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1046835|intact:EBI-28986171|ensembl:ENSP00000356290|uniprotkb:Q2TBF3|uniprotkb:Q8WVW0|uniprotkb:Q96HG8|uniprotkb:Q9H789|uniprotkb:Q9UFU8	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:c1tm_human(display_long)|uniprotkb:MTHFD1L(gene name)|psi-mi:MTHFD1L(display_short)|uniprotkb:FTHFSDC1(gene name synonym)|uniprotkb:Formyltetrahydrofolate synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000120254(gene)|ensembl:ENST00000367321(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006760"(folic acid-containing compound metabolic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0015942"(formate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR027417|interpro:IPR036291|reactome:R-HSA-196757|refseq:NP_001229696.1|refseq:NP_001229697.1|refseq:NP_001229698.1|refseq:NP_056255.2|ensembl:ENST00000367307|ensembl:ENSP00000356276|ensembl:ENSP00000356290	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:lJRND1kcMEF99+fT1b+X8hfuLHM9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q5JTZ9	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q5HY81	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-21266296|ensembl:ENSP00000358667	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:q5hy81_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000102178(gene)|ensembl:ENST00000369653(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|interpro:IPR000626(Ubiquitin)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:hsvCyYhEhExCs0h/V/1j7UryjO49606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q3MHD2	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q16718	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q12931	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:Q08380	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P63167	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P61981	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P54886	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P51570	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P49411	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P42765	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P32322	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P30042	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P16070	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-490245|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370|ensembl:ENSP00000398632	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|ensembl:ENSG00000026508(gene)|ensembl:ENST00000428726(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051216"(cartilage development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|dip:DIP-1121N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P13073	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P06493	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:P05091	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-711703|uniprotkb:Q03639|uniprotkb:Q6IB13|uniprotkb:Q6IV71|uniprotkb:B4DW54|uniprotkb:E7EUE5|ensembl:ENSP00000261733	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:aldh2_human(display_long)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)|uniprotkb:ALDH2(gene name)|psi-mi:ALDH2(display_short)|uniprotkb:ALDM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_000681.2|refseq:NP_001191818.1|dip:DIP-40262N|ensembl:ENSG00000111275(gene)|ensembl:ENST00000261733(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P05091|rcsb pdb:1CW3|rcsb pdb:1NZW|rcsb pdb:1NZX|rcsb pdb:1NZZ|rcsb pdb:1O00|rcsb pdb:1O01|rcsb pdb:1O02|rcsb pdb:1O04|rcsb pdb:1O05|rcsb pdb:1ZUM|rcsb pdb:2ONM|rcsb pdb:2ONN|rcsb pdb:2ONO|rcsb pdb:2ONP|rcsb pdb:2VLE|rcsb pdb:3INJ|rcsb pdb:3INL|rcsb pdb:3N80|rcsb pdb:3N81|rcsb pdb:3N82|rcsb pdb:3N83|rcsb pdb:3SZ9|rcsb pdb:4FQF|rcsb pdb:4FR8|rcsb pdb:4KWF|rcsb pdb:4KWG|rcsb pdb:5L13|reactome:R-HSA-380612|reactome:R-HSA-71384	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:XvszkFUJP4cXHCYokY16c+LeDEI9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:O95071	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:O75306	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:O43837	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:O14744	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:C9JLW8	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:A8MXV4	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-11350801|ensembl:ENSP00000380251	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:nud19_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 19(gene name synonym)|uniprotkb:NUDT19(gene name)|psi-mi:NUDT19(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	refseq:NP_001099040.1|ensembl:ENSG00000213965(gene)|ensembl:ENST00000397061(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0010945"(CoA pyrophosphatase activity)|go:"GO:0015938"(coenzyme A catabolic process)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0044580"(butyryl-CoA catabolic process)|go:"GO:1901289"(succinyl-CoA catabolic process)|go:"GO:1902858"(propionyl-CoA metabolic process)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR039121|reactome:R-HSA-390918|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:nSyCFhGmUMc1wbmmLp6RZvUojaM9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O00220	uniprotkb:A8MXH2	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-21262770|ensembl:ENSP00000382523|ensembl:ENSP00000487901	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:a8mxh2_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266309|imex:IM-26691-95	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000399614(transcript)|ensembl:ENST00000634217(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:oqZISVLJYMBgTjnNm0Lolfl6lOs9606	rigid:PK/HScKt7aM5R30/jKaT7sc5Dkg	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q5W0V3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-7054959|uniprotkb:Q8IY76|uniprotkb:Q5H9P7|uniprotkb:Q9HCH2|uniprotkb:Q5W0V2|intact:MINT-8201763|ensembl:ENSP00000358251	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:fhi2a_human(display_long)|uniprotkb:FHIP2A(gene name)|psi-mi:FHIP2A(display_short)|uniprotkb:FAM160B1(gene name synonym)|uniprotkb:KIAA1600(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001128523.1|refseq:NP_065991.3|ensembl:ENSG00000151553(gene)|ensembl:ENST00000369248(transcript)|interpro:IPR019384|mint:Q5W0V3	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:ztLSJ/Jf2V5nrPCwlBZfAzmrmzM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9Y6E2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9Y678	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9UPT5	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|ensembl:ENSG00000182473(gene)|ensembl:ENST00000335146(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032584"(growth cone membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_001269242.1|dip:DIP-37604N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9UNS2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9UI26	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9UI10	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9UBQ5	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9NV70	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9NU22	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9NTJ3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9NR50	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9HAV4	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9H8T0	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-711399|uniprotkb:Q503B1|uniprotkb:Q53H38|ensembl:ENSP00000378152|ensembl:ENSP00000455874	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:aktip_human(display_long)|uniprotkb:AKTIP(gene name)|psi-mi:AKTIP(display_short)|uniprotkb:Ft1(gene name synonym)|uniprotkb:FTS(gene name synonym)|uniprotkb:Fused toes protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001295254.1|refseq:NP_001012398.1|refseq:NP_071921.1|refseq:XP_005256152.1|refseq:XP_005256153.1|refseq:XP_005256154.1|refseq:XP_005256155.1|refseq:XP_016879053.1|refseq:XP_016879054.1|refseq:XP_016879055.1|ensembl:ENSG00000166971(gene)|ensembl:ENST00000394657(transcript)|ensembl:ENST00000570004(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:rCCRz3YF0NI1/xGHNUw7LpOvDGQ9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9GZT3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9C0E2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9BXW9	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9BW27	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-716392|intact:EBI-2563151|uniprotkb:Q9H9U1|uniprotkb:Q8NDI4|uniprotkb:B4DMQ3|uniprotkb:B4DPW1|ensembl:ENSP00000245544	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:nup85_human(display_long)|uniprotkb:PCNT1(gene name synonym)|uniprotkb:Nucleoporin Nup85(gene name synonym)|uniprotkb:85 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup75(gene name synonym)|uniprotkb:Pericentrin-1(gene name synonym)|uniprotkb:FROUNT(gene name synonym)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:NUP75(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_079120.1|refseq:NP_001290205.1|ensembl:ENSG00000125450(gene)|ensembl:ENST00000245544(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0072006"(nephron development)|interpro:IPR011502(Nucleoporin, Nup85-like)|mint:Q9BW27|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:MWeo3e2aXVKhP1gFV8ZZrgyFSeI9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q9BPX3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:G45XQBcnTeSunRz57s6lJErxvjo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q96P70	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q96KP1	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|ensembl:ENSP00000230449|uniprotkb:B2RBE6	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000112685(gene)|ensembl:ENST00000230449(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|dip:DIP-31795N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q96ER3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q96ED9	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-743290|uniprotkb:O60562|ensembl:ENSP00000380785	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:hook2_human(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001093646.1|refseq:NP_037444.2|ensembl:ENSG00000095066(gene)|ensembl:ENST00000397668(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006897"(endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q96ED9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:ryVqr8ZYjAc5SuoRR/zMQxnh0O89606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q96CP6	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1384139|uniprotkb:A6NKY7|uniprotkb:Q8NC77|uniprotkb:Q9P1Z5|ensembl:ENSP00000441032	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:astra_human(display_long)|uniprotkb:GRAMD1A(gene name)|psi-mi:GRAMD1A(display_short)|uniprotkb:KIAA1533(gene name synonym)|uniprotkb:GRAM domain-containing protein 1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001306964.1|refseq:NP_001129671.1|refseq:NP_065946.2|refseq:NP_001306963.1|refseq:NP_001306965.1|ensembl:ENSG00000089351(gene)|ensembl:ENST00000317991(transcript)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|mint:Q96CP6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:S7fzTVbf+LB0tpV7JvPZzpcs8709606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q92973	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q8WUM0	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q8TEQ6	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q8TCG1	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q8TC07	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q8N6T3	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-716933|uniprotkb:Q6PK71|uniprotkb:Q96KC4|uniprotkb:Q96T02|uniprotkb:Q9NSU3|uniprotkb:Q9NVF6|uniprotkb:Q9UIL0|uniprotkb:B7ZBI3|uniprotkb:E1P5I9|ensembl:ENSP00000359306|uniprotkb:B7Z3U0|uniprotkb:E7EV62|uniprotkb:B7Z8H8	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:arfg1_human(display_long)|uniprotkb:ADP-ribosylation factor 1 GTPase-activating protein(gene name synonym)|uniprotkb:ARF1-directed GTPase-activating protein(gene name synonym)|uniprotkb:ARFGAP1(gene name)|psi-mi:ARFGAP1(display_short)|uniprotkb:ARF1GAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_060679.1|refseq:NP_783202.1|refseq:NP_001268411.1|refseq:NP_001268412.1|refseq:NP_001268413.1|ensembl:ENSG00000101199(gene)|ensembl:ENST00000370283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|mint:Q8N6T3|rcsb pdb:3DWD|rcsb pdb:3O47|reactome:R-HSA-381038|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8856828	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:vAIMUqWHtBQzZYe5JJp6WEMXQdo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q86XI2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1047404|uniprotkb:Q7Z3J9|uniprotkb:Q8WUG8|uniprotkb:Q9BRX6|uniprotkb:Q9H8S2|uniprotkb:Q9H9K6|uniprotkb:A4D228|ensembl:ENSP00000348657|ensembl:ENSP00000386569	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:cndg2_human(display_long)|uniprotkb:Chromosome-associated protein G2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit G2(gene name synonym)|uniprotkb:Leucine zipper protein 5(gene name synonym)|uniprotkb:NCAPG2(gene name)|psi-mi:NCAPG2(display_short)|uniprotkb:LUZP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_060230.5|refseq:XP_011514658.1|refseq:XP_011514659.1|ensembl:ENSG00000146918(gene)|ensembl:ENST00000356309(transcript)|ensembl:ENST00000409423(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000796"(condensin complex)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030293"(transmembrane receptor protein tyrosine kinase inhibitor activity)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0051301"(cell division)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024741|mint:Q86XI2|reactome:R-HSA-2299718|interpro:IPR011989(Armadillo-like helical)|refseq:NP_001268861.1|refseq:NP_001268862.1|dip:DIP-43902N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:4JkTPdyKz1cYblG0ZU0vQKMsuB49606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q86W92	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000110841(gene)|ensembl:ENST00000318304(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030437|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q86VS8	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1777078|uniprotkb:Q8NBH0|uniprotkb:Q9BY13|uniprotkb:D3DSY8|ensembl:ENSP00000305699	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:hook3_human(display_long)|uniprotkb:HOOK3(gene name)|psi-mi:HOOK3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_115786.1|ensembl:ENSG00000168172(gene)|ensembl:ENST00000307602(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|rcsb pdb:5J8E|rcsb pdb:6B9H|go:"GO:0034454"(microtubule anchoring at centrosome)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:hzM38dyr89rY7z71px9K4rVNL6s9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q86VP6	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q7Z4Q2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q70CQ2	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-6256020|uniprotkb:A8MWD0|uniprotkb:B3KWU9|uniprotkb:O60316|uniprotkb:O94834|uniprotkb:Q3B777|uniprotkb:Q6P6C9|uniprotkb:Q7L8P6|uniprotkb:Q8N3T9|uniprotkb:Q8TBW2|uniprotkb:Q9UGA1|ensembl:ENSP00000381577	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ubp34_human(display_long)|uniprotkb:USP34(gene name)|psi-mi:USP34(display_short)|uniprotkb:KIAA0570(gene name synonym)|uniprotkb:KIAA0729(gene name synonym)|uniprotkb:Deubiquitinating enzyme 34(gene name synonym)|uniprotkb:Ubiquitin thioesterase 34(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055524.3|ensembl:ENSG00000115464(gene)|ensembl:ENST00000398571(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|mint:Q70CQ2|reactome:R-HSA-201681|reactome:R-HSA-5689880	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:ouPBRH6ndkATju67iwZYOl1wYWM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q5TH69	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-5235513|uniprotkb:C5NM88|uniprotkb:Q76MU8|uniprotkb:Q8N4Y4|uniprotkb:Q96CH9|uniprotkb:Q96P46|uniprotkb:Q9ULH6|ensembl:ENSP00000251691	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:big3_human(display_long)|uniprotkb:ARFGEF3(gene name)|psi-mi:ARFGEF3(display_short)|uniprotkb:BIG3(gene name synonym)|uniprotkb:C6orf92(gene name synonym)|uniprotkb:KIAA1244(gene name synonym)|uniprotkb:ARFGEF family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_065073.3|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|go:"GO:0030658"(transport vesicle membrane)|ensembl:ENSG00000112379(gene)|ensembl:ENST00000251691(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:aIEMWbaJHhD/6xtohTJxz6xbNVY9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q5SRE5	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1049404|uniprotkb:Q14675|uniprotkb:Q2TA87|uniprotkb:Q7Z3K8|uniprotkb:Q8IWF1|intact:EBI-2555229|ensembl:ENSP00000361658	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:nu188_human(display_long)|uniprotkb:NUP188(gene name)|psi-mi:NUP188(display_short)|uniprotkb:KIAA0169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_056169.1|ensembl:ENSG00000095319(gene)|ensembl:ENST00000372577(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018864|interpro:IPR044840|mint:Q5SRE5|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:eoj+tg9RAVKcVlT9ku1ozXCa3u89606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q3KR37	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21266442|intact:EBI-28974840|ensembl:ENSP00000436500|uniprotkb:B3KXJ5|uniprotkb:E7EPH8|uniprotkb:Q6UW85|uniprotkb:Q9ULL9	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:astrb_human(display_long)|uniprotkb:GRAMD1B(gene name)|psi-mi:GRAMD1B(display_short)|uniprotkb:KIAA1201(gene name synonym)|uniprotkb:UNQ3032/PRO9834(orf name)|uniprotkb:GRAM domain-containing protein 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENST00000450171|ensembl:ENSP00000388458|ensembl:ENST00000456860|ensembl:ENSP00000402457|ensembl:ENST00000529432|ensembl:ENSP00000432987|ensembl:ENSP00000436500|ensembl:ENSG00000023171(gene)|ensembl:ENST00000529750(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|go:"GO:0070300"(phosphatidic acid binding)|refseq:NP_001273492.1|refseq:NP_001273493.1|refseq:NP_065767.1|refseq:XP_016873536.1|refseq:XP_016873537.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:F6+FZKNtZb1apJxzlcANfQnZMnQ9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q29RF7	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q16637	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q15645	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q15386	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q15058	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1045252|uniprotkb:Q14CI8|uniprotkb:Q4G0A5|uniprotkb:Q5T1W3|ensembl:ENSP00000356319|ensembl:ENSP00000483069	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:kif14_human(display_long)|uniprotkb:KIF14(gene name)|psi-mi:KIF14(display_short)|uniprotkb:KIAA0042(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055690.1|ensembl:ENSG00000118193(gene)|ensembl:ENST00000367350(transcript)|ensembl:ENST00000614960(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021685"(cerebellar granular layer structural organization)|go:"GO:0021693"(cerebellar Purkinje cell layer structural organization)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033624"(negative regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0090543"(Flemming body)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903429"(regulation of cell maturation)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|mint:Q15058|reactome:R-HSA-5625900|reactome:R-HSA-9696270|reactome:R-HSA-9696273|go:"GO:0021772"(olfactory bulb development)|refseq:NP_001292721.1|refseq:XP_011508533.1|refseq:XP_011508534.1|refseq:XP_016858494.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:xIx+ywoBoaILDgAkmzxHOtF15DA9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q15021	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q14974	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q14232	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|uniprotkb:B4DGX0|ensembl:ENSP00000416250	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ei2ba_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001405.1|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000111361(gene)|ensembl:ENST00000424014(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q13144	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:Q00653	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P78527	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P61981	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P57678	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P56192	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|uniprotkb:B3KVK7|ensembl:ENSP00000262027	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|reactome:R-HSA-379716|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|refseq:NP_004981.2|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000166986(gene)|ensembl:ENST00000262027(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|dip:DIP-38164N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P55083	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-2829794|uniprotkb:Q6P680|uniprotkb:A8KAJ1|uniprotkb:A8MVM2|uniprotkb:B4E317|ensembl:ENSP00000299610	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:mfap4_human(display_long)|uniprotkb:MFAP4(gene name)|psi-mi:MFAP4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001185624.1|refseq:NP_002395.1|ensembl:ENSG00000166482(gene)|ensembl:ENST00000299610(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009650"(UV protection)|go:"GO:0010712"(regulation of collagen metabolic process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0071953"(elastic fiber)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0097435"(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|reactome:R-HSA-2129379	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:pudRJmT0Rb32WgBHT7g7KZsSsME9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P55060	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P52701	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P51648	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P49815	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-396587|uniprotkb:O75275|uniprotkb:Q8TAZ1|uniprotkb:A7E2E2|uniprotkb:B4DIQ7|uniprotkb:B4DRN2|uniprotkb:Q4LE71|uniprotkb:C9J378|ensembl:ENSP00000219476|uniprotkb:B4DIL8|uniprotkb:B7Z2B8	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:tsc2_human(display_long)|uniprotkb:TSC2(gene name)|psi-mi:TSC2(display_short)|uniprotkb:Tuberous sclerosis 2 protein(gene name synonym)|uniprotkb:TSC4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000539.2|refseq:NP_001070651.1|refseq:NP_001107854.1|ensembl:ENSG00000103197(gene)|ensembl:ENST00000219476(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006897"(endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|refseq:NP_001305756.1|refseq:NP_001305758.1|refseq:NP_001305760.1|refseq:NP_001305761.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043276"(anoikis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:1901525"(negative regulation of mitophagy)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018515|interpro:IPR024584|interpro:IPR027107|interpro:IPR035974|mint:P49815|rcsb pdb:7DL2|reactome:R-HSA-1632852|reactome:R-HSA-165181|reactome:R-HSA-198323|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-8854214|refseq:XP_005255586.2|refseq:XP_016879105.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:II0K3oybyrXfM4GEYMwV2ZyoWwE9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P49792	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P49770	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-718773|uniprotkb:O43201|ensembl:ENSP00000266126	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ei2bb_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:S20I15(gene name synonym)|uniprotkb:S20III15(gene name synonym)|uniprotkb:EIF2B2(gene name)|psi-mi:EIF2B2(display_short)|uniprotkb:EIF2BB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_055054.1|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007417"(central nervous system development)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000119718(gene)|ensembl:ENST00000266126(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:CLCdt90SBzvMUBXSQDb6DTy3Yz09606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P43246	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P42345	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P27348	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P10909	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:P02786	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O95373	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O95347	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O75694	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O60518	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1055771|uniprotkb:Q5T7X4|uniprotkb:Q7Z3V2|uniprotkb:Q96E78|ensembl:ENSP00000259569	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:rnbp6_human(display_long)|uniprotkb:RANBP6(gene name)|psi-mi:RANBP6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_036548.1|refseq:NP_001230131.1|refseq:NP_001230132.1|ensembl:ENSG00000137040(gene)|ensembl:ENST00000259569(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|mint:O60518	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:3yh3vq2Bj+aqE9zWUU9LET7en6g9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O43592	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O15397	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O14980	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:O00469	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:E1NZA1	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21258417	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:C9JGV6	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21262803|ensembl:ENSP00000404298	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:c9jgv6_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000099901(gene)|ensembl:ENST00000423859(transcript)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:qjeGKWvXwtiE7cqLu8wKiZ61Z8I9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:C9JA93	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21266432|ensembl:ENSP00000418091	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:c9ja93_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000121749(gene)|ensembl:ENST00000491063(transcript)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:KNZazmT2NQ9mGrix0v5orson30w9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:C9J470	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21258863|ensembl:ENSP00000405237	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:c9j470_human(display_long)|uniprotkb:NCAPH(gene name)|psi-mi:NCAPH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSG00000121152(gene)|ensembl:ENST00000435975(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|interpro:IPR022816	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:lQwu9inrN64YhVd4Bvtoc9WEAOw9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:B7ZM73	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21260321	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y275	uniprotkb:B2RWN5	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-21258368	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266480|imex:IM-26691-155	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	rigid:e2DLL9z3kuMPL4p/9z/5hIKsDKE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q969M3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2124787|uniprotkb:Q4VSN6|uniprotkb:Q53EX4|uniprotkb:Q8NHE5|uniprotkb:Q9H338|uniprotkb:Q9H3U4|uniprotkb:D3DQF5|ensembl:ENSP00000274496|ensembl:ENSP00000397704	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:yipf5_human(display_long)|uniprotkb:YIPF5(gene name)|psi-mi:YIPF5(display_short)|uniprotkb:FINGER5(gene name synonym)|uniprotkb:YIP1A(gene name synonym)|uniprotkb:YIP1 family member 5(gene name synonym)|uniprotkb:YPT-interacting protein 1 A(gene name synonym)|uniprotkb:Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 5(gene name synonym)|uniprotkb:PP12723(orf name)|uniprotkb:SB140(orf name)|uniprotkb:UNQ3123/PRO10275(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001020118.1|refseq:NP_110426.4|refseq:NP_001258661.1|ensembl:ENST00000274496(transcript)|ensembl:ENST00000448443(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070971"(endoplasmic reticulum exit site)|mint:Q969M3|ensembl:ENSG00000145817(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:tNd/CdASqK/08G9O9h3nivCTzKw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q13315	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|intact:EBI-28985245|ensembl:ENSP00000278616|ensembl:ENSP00000388058|ensembl:ENSP00000501606	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000042.3|refseq:XP_011541142.1|ensembl:ENSP00000501606|ensembl:ENSP00000278616|ensembl:ENSP00000388058|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|dip:DIP-182N|refseq:XP_016873278.1|refseq:XP_016873279.1|ensembl:ENSG00000149311(gene)|ensembl:ENST00000452508(transcript)|ensembl:ENST00000675843(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0003677"(DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007165"(signal transduction)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904354"(negative regulation of telomere capping)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR015519(Ataxia-Telangiectasia Mutated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR044107|ensembl:ENST00000278616(transcript)|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-6804757	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O43615	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-861737|uniprotkb:Q8N193|uniprotkb:A8K0R9|uniprotkb:D6W664|ensembl:ENSP00000270538	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tim44_human(display_long)|uniprotkb:TIMM44(gene name)|psi-mi:TIMM44(display_short)|uniprotkb:MIMT44(gene name synonym)|uniprotkb:TIM44(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006342.2|ensembl:ENSG00000104980(gene)|ensembl:ENST00000270538(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0051087"(chaperone binding)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR017303(Import inner membrane translocase, TIM44 subunit, mitochondria)|interpro:IPR032710|interpro:IPR039544|mint:O43615|rcsb pdb:2CW9|reactome:R-HSA-1268020	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Hwln5XuF3a9IMwVhP63Ud+LM5M09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O43264	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:A2RRP1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056993.2|dip:DIP-56726N|ensembl:ENSG00000151779(gene)|ensembl:ENST00000281513(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR029145|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9GZP9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92643	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WVC6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11319548|uniprotkb:Q9H5W1|uniprotkb:D3DX62|uniprotkb:D3DX60|uniprotkb:A8K3Z0|uniprotkb:Q9BR71|ensembl:ENSP00000308515|ensembl:ENSP00000341504|ensembl:ENSP00000413483|ensembl:ENSP00000467913|ensembl:ENSP00000478909|ensembl:ENSP00000498268	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dcakd_human(display_long)|uniprotkb:DCAKD(gene name)|psi-mi:DCAKD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_016880591.1|refseq:XP_016880592.1|refseq:XP_016880593.1|refseq:NP_001122103.1|refseq:NP_001275583.1|refseq:NP_001275584.1|refseq:NP_079095.3|refseq:XP_005257745.1|refseq:XP_011523564.1|refseq:NP_001308255.1|ensembl:ENST00000651974(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016020"(membrane)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|mint:Q8WVC6|ensembl:ENSG00000172992(gene)|ensembl:ENST00000310604(transcript)|ensembl:ENST00000342350(transcript)|ensembl:ENST00000452796(transcript)|ensembl:ENST00000588499(transcript)|ensembl:ENST00000614054(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:b6jKOSLEjdHLqm69BmVHjW8R5G49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8N3P4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-7261494|intact:MINT-1196904|uniprotkb:Q9BVP9|uniprotkb:Q63HP2|uniprotkb:C9JB61|uniprotkb:O94896|uniprotkb:Q9H9B0|uniprotkb:A8K8Q8|uniprotkb:B9EIQ1|ensembl:ENSP00000487164	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vps8_human(display_long)|uniprotkb:VPS8(gene name)|psi-mi:VPS8(display_short)|uniprotkb:KIAA0804(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001009921.1|refseq:NP_056118.2|refseq:XP_005247308.1|ensembl:ENST00000625842(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0015031"(protein transport)|go:"GO:0033263"(CORVET complex)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025941|interpro:IPR036322|ensembl:ENSG00000156931(gene)	-	-	comment:mint|comment:homomint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:bV6Coru+kAusoFb1qAV6Z5Na9849606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6PIW4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-8468390|uniprotkb:D3DVM6|intact:MINT-4940916|intact:MINT-4926768|uniprotkb:Q86V18|intact:MINT-4920988|uniprotkb:Q9H8P1|intact:MINT-4908266|intact:MINT-3069016|uniprotkb:Q9H917|uniprotkb:Q8ND59|ensembl:ENSP00000349356|ensembl:ENSP00000378924|ensembl:ENSP00000399997|ensembl:ENSP00000410811|ensembl:ENSP00000481751|ensembl:ENSP00000483126|ensembl:ENSP00000483543|ensembl:ENSP00000484551	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:figl1_human(display_long)|uniprotkb:FIGNL1(gene name)|psi-mi:FIGNL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001333487.1|refseq:NP_001333488.1|refseq:NP_001333489.1|refseq:NP_001333490.1|refseq:NP_001333491.1|refseq:NP_001333492.1|refseq:NP_001333493.1|refseq:NP_001333494.1|refseq:XP_011513772.1|refseq:NP_071399.2|refseq:NP_001036227.1|refseq:NP_001274421.1|refseq:NP_001274422.1|refseq:NP_001274423.1|refseq:NP_001274424.1|refseq:NP_001274425.1|refseq:XP_016867990.1|ensembl:ENSG00000132436(gene)|ensembl:ENST00000356889(transcript)|ensembl:ENST00000395556(transcript)|ensembl:ENST00000419119(transcript)|ensembl:ENST00000433017(transcript)|ensembl:ENST00000611938(transcript)|ensembl:ENST00000613602(transcript)|ensembl:ENST00000615084(transcript)|ensembl:ENST00000617389(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|mint:Q6PIW4|rcsb pdb:3D8B	-	-	comment:mint|comment:homomint|function:May regulate osteoblast proliferation and differentiation	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Up69HKKMMUtt3/8MYUxUCcW002c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:X5CMH5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262914|ensembl:ENSP00000393580|ensembl:ENSP00000406540|ensembl:ENSP00000416471	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:x5cmh5_human(display_long)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000223481(gene)|ensembl:ENSG00000225967(gene)|ensembl:ENSG00000232326(gene)|ensembl:ENST00000452371(transcript)|ensembl:ENST00000455842(transcript)|ensembl:ENST00000457634(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005524"(ATP binding)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0042287"(MHC protein binding)|go:"GO:0042825"(TAP complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|refseq:NP_000535.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:c5RxmRf2D24+XCfzlzKnDvh80fM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:U3KQ84	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262903|ensembl:ENSP00000475634	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:u3kq84_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000244038(gene)|ensembl:ENST00000464364(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:NGgqak8QRgCkgA8i0YquXgL3f909606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y679	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y5L0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y4R8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|ensembl:ENSP00000262319|uniprotkb:D3DU73	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000100726(gene)|ensembl:ENST00000262319(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|mint:Q9Y4R8|rcsb pdb:4PSI|refseq:NP_057195.2|refseq:XP_016879403.1|dip:DIP-40568N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y448	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-373334|uniprotkb:Q147U5|uniprotkb:Q32Q57|uniprotkb:Q5ISJ0|uniprotkb:Q6P2S5|uniprotkb:Q6PJM0|uniprotkb:Q86XB4|uniprotkb:B4DXA7|ensembl:ENSP00000249776|intact:EBI-2555320	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:skap_human(display_long)|uniprotkb:KNSTRN(gene name)|psi-mi:KNSTRN(display_short)|uniprotkb:C15orf23(gene name synonym)|uniprotkb:Kinetochore-localized astrin-binding protein(gene name synonym)|uniprotkb:Kinetochore-localized astrin/SPAG5-binding protein(gene name synonym)|uniprotkb:SKAP(gene name synonym)|uniprotkb:TRAF4-associated factor 1(gene name synonym)|uniprotkb:TRAF4AF1(gene name synonym)|uniprotkb:HSD11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001136233.1|refseq:NP_001136234.1|refseq:NP_150628.3|ensembl:ENSG00000128944(gene)|ensembl:ENST00000249776(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|dip:DIP-31247N|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016477"(cell migration)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072686"(mitotic spindle)|interpro:IPR033373	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:48DI5G7v8vAeEMOZpyhAOcmFhc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y3Z3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y3F4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y3E5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y3D8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2896123|ensembl:ENSP00000370201|ensembl:ENSP00000484679|uniprotkb:A8MSZ6|uniprotkb:Q5F2S9	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:kad6_human(display_long)|uniprotkb:AK6(gene name)|psi-mi:AK6(display_short)|uniprotkb:Adrenal gland protein AD-004(gene name synonym)|uniprotkb:CINAP(gene name synonym)|uniprotkb:Coilin-interacting nuclear ATPase protein(gene name synonym)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:AD-004(orf name)|uniprotkb:CGI-137(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000085231(gene)|ensembl:ENSG00000279247(gene)|ensembl:ENST00000380822(transcript)|ensembl:ENST00000612207(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|interpro:IPR020618|interpro:IPR027417|rcsb pdb:1RKB|rcsb pdb:3IIJ|rcsb pdb:3IIK|rcsb pdb:3IIL|rcsb pdb:3IIM|rcsb pdb:5JZV|go:"GO:0005524"(ATP binding)|reactome:R-HSA-499943|refseq:NP_001015891.1|refseq:NP_057367.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:95R1JCsp5rHT9UrpRMXhhxrrlr89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y3D0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y2V7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3866319|uniprotkb:Q86V49|uniprotkb:Q5T0U1|uniprotkb:Q9ULT5|uniprotkb:Q6AI19|ensembl:ENSP00000397441	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog6_human(display_long)|uniprotkb:COG6(gene name)|psi-mi:COG6(display_short)|uniprotkb:KIAA1134(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001138551.1|refseq:NP_065802.1|dip:DIP-48931N|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0070085"(glycosylation)|interpro:IPR010490(Conserved oligomeric complex COG6)|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|ensembl:ENSG00000133103(gene)|ensembl:ENST00000455146(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:1S6ym3UxcjqPpQ9WCWf3060I9jE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y277	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9Y241	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UPT5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|ensembl:ENSG00000182473(gene)|ensembl:ENST00000335146(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032584"(growth cone membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_001269242.1|dip:DIP-37604N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UPN7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UP83	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-389502|uniprotkb:A4D0R6|uniprotkb:A4D0R7|uniprotkb:Q6NUL5|uniprotkb:O14555|uniprotkb:O95008|ensembl:ENSP00000297135|ensembl:ENSP00000334703|ensembl:ENSP00000377228	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog5_human(display_long)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001154992.1|refseq:NP_006339.3|refseq:NP_859422.2|ensembl:ENSG00000164597(gene)|ensembl:ENST00000297135(transcript)|ensembl:ENST00000347053(transcript)|ensembl:ENST00000393603(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR019465|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Jytff1Ttr5vNSps1MeFz2ZoP1Kg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UN37	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UJZ1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UII2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UI26	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UI12	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UI10	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UHI6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UGP8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UFG5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-741214|intact:EBI-28979499|ensembl:ENSP00000397394|ensembl:ENSP00000466372|ensembl:ENSP00000467861|ensembl:ENSP00000468688|uniprotkb:Q8N9R7|uniprotkb:Q8WV94|uniprotkb:B3KQN6|intact:EBI-2561342	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cs025_human(display_long)|uniprotkb:C19orf25(gene name)|psi-mi:C19orf25(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_689695.2|ensembl:ENSG00000119559(gene)|ensembl:ENST00000436106(transcript)|ensembl:ENST00000585675(transcript)|ensembl:ENST00000586564(transcript)|ensembl:ENST00000592872(transcript)|interpro:IPR028227|ensembl:ENSP00000397394|ensembl:ENSP00000468688|ensembl:ENSP00000466372|ensembl:ENSP00000467861|refseq:XP_006722716.1|refseq:XP_005259563.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8x4kfH5+Et/gOjw93ulVXPlAync9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UBV2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9UBF2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9P2J5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79|uniprotkb:A7E266|ensembl:ENSP00000377954	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_064502.9|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:XP_011535958.1|ensembl:ENSG00000133706(gene)|ensembl:ENST00000394434(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0012505"(endomembrane system)|go:"GO:0016604"(nuclear body)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9P0L0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9P035	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9P032	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NZ01	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NYU2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NXW2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NXE4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-372102|uniprotkb:Q6FI76|uniprotkb:Q6P1P7|uniprotkb:Q6ZT43|uniprotkb:Q9H0M2|uniprotkb:Q9NW20|uniprotkb:Q9NWL2|uniprotkb:Q9P2C9|uniprotkb:B4DWK7|uniprotkb:E9PCE6|intact:EBI-1058838|ensembl:ENSP00000386531|uniprotkb:B4DRB8|uniprotkb:E7ESA2|uniprotkb:B4DM23|uniprotkb:B4DQ31|uniprotkb:B4E0L6|uniprotkb:B1PBA3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nsma3_human(display_long)|uniprotkb:SKNY(gene name synonym)|uniprotkb:SMPD4(gene name)|psi-mi:SMPD4(display_short)|uniprotkb:Neutral sphingomyelinase 3(gene name synonym)|uniprotkb:Neutral sphingomyelinase III(gene name synonym)|uniprotkb:KIAA1418(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001164554.1|refseq:NP_060221.2|refseq:XP_011509747.1|refseq:NP_060421.2|ensembl:ENSG00000136699(gene)|ensembl:ENST00000409031(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006685"(sphingomyelin catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050290"(sphingomyelin phosphodiesterase D activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR024129|reactome:R-HSA-1660662|refseq:XP_016859937.1|refseq:XP_016859938.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/OGzQcEQfrn7jgedtceXIuns7449606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NVI1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NV70	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NU22	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NTJ5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NTJ3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NSG2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11128910|uniprotkb:Q9NVJ0|uniprotkb:B3KU42|uniprotkb:Q9H8L5|uniprotkb:Q3KNQ1|uniprotkb:A6NFP1|ensembl:ENSP00000286031|ensembl:ENSP00000352276	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ca112_human(display_long)|uniprotkb:C1orf112(gene name)|psi-mi:C1orf112(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001306976.1|refseq:NP_001306977.1|refseq:NP_060656.2|refseq:XP_011508037.1|refseq:NP_001306979.1|refseq:NP_001306980.1|refseq:XP_016857213.1|refseq:XP_016857214.1|ensembl:ENSG00000000460(gene)|ensembl:ENST00000286031(transcript)|ensembl:ENST00000359326(transcript)|interpro:IPR027902	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Jy6nCLVYtB3BgdCuu0RLRfmAAVc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NRZ5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1754287|uniprotkb:Q5TEF0|uniprotkb:B4DSF9|ensembl:ENSP00000314036	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:plcd_human(display_long)|uniprotkb:AGPAT4(gene name)|psi-mi:AGPAT4(display_short)|uniprotkb:Lysophosphatidic acid acyltransferase delta(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 4(gene name synonym)|uniprotkb:UNQ499/PRO1016(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_064518.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|reactome:R-HSA-1483166|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENSG00000026652(gene)|ensembl:ENST00000320285(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:9yka/zqR6zJd1dH0SdvTDnFeXVU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NRG9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3912901|uniprotkb:Q9UG19|uniprotkb:Q9NWI6|uniprotkb:Q5JB47|ensembl:ENSP00000209873	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:aaas_human(display_long)|uniprotkb:AAAS(gene name)|psi-mi:AAAS(display_short)|uniprotkb:ADRACALA(gene name synonym)|uniprotkb:Adracalin(gene name synonym)|uniprotkb:GL003(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001166937.1|refseq:NP_056480.1|ensembl:ENSG00000094914(gene)|ensembl:ENST00000209873(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007612"(learning)|go:"GO:0009566"(fertilization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-8980692|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:fdOcZ59NldwaQJ6nusjn8GAhszo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NR50	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NP72	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9HAV4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9H9E3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-368382|uniprotkb:Q96D40|uniprotkb:Q9BRF0|uniprotkb:Q9BVZ2|uniprotkb:Q9H5Y4|uniprotkb:Q9Y3W3|uniprotkb:B4DMN8|uniprotkb:C9JS23	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog4_human(display_long)|uniprotkb:COG4(gene name)|psi-mi:COG4(display_short)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	mint:Q9H9E3|refseq:NP_001182068.1|refseq:NP_056201.2|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization)|interpro:IPR013167(COG4 transport)|rcsb pdb:3HR0|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|dip:DIP-32635N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Zphojrpw0bzNCK/pnMNps+K1y7U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9H845	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9H7F0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9H4A6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9H078	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9C0E8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1047206|ensembl:ENSP00000272748|uniprotkb:Q2M2V8|uniprotkb:Q2YD99|uniprotkb:Q658W8|uniprotkb:Q8N5V9|uniprotkb:Q96MS5|uniprotkb:B7ZLA8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:lnp_human(display_long)|uniprotkb:ER junction formation factor lunapark(gene name synonym)|uniprotkb:LNPK(gene name)|psi-mi:LNPK(display_short)|uniprotkb:KIAA1715(gene name synonym)|uniprotkb:LNP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000144320(gene)|ensembl:ENST00000272748(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|refseq:NP_085153.1|refseq:NP_001291937.1|refseq:NP_001291938.1|refseq:NP_001291940.1|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060173"(limb development)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR019273|interpro:IPR040115|refseq:XP_006712846.1|refseq:XP_016860544.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:7iBa9RbcYnDjAjIU4v0rez5Bhn49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9C0E2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BXW9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BVK6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BVC6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1057733|ensembl:ENSP00000227525|ensembl:ENSP00000443990	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_076997.1|ensembl:ENSG00000110108(gene)|ensembl:ENST00000227525(transcript)|ensembl:ENST00000536171(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BVA1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BTX1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BTV4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BSJ2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9BQ95	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q99873	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q99653	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q99623	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q99442	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-949221|ensembl:ENSP00000337688|ensembl:ENSP00000420331|uniprotkb:O00682|uniprotkb:O00729|intact:EBI-2689278|uniprotkb:D3DNQ0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sec62_human(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:TLOC1(gene name synonym)|uniprotkb:Translocation protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000008952(gene)|ensembl:ENST00000337002(transcript)|ensembl:ENST00000480708(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR004728(Translocation protein Sec62)|rcsb pdb:7BRT|refseq:NP_003253.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:u7na6TjTcixVS+ZK2ygkFA1QDKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96T76	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96SK2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10963859|ensembl:ENSP00000380747|uniprotkb:Q6PF00|uniprotkb:Q96SL6|uniprotkb:A4D1L1|uniprotkb:Q8NCH3|uniprotkb:Q49A50	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tm209_human(display_long)|uniprotkb:TMEM209(gene name)|psi-mi:TMEM209(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001288092.1|refseq:NP_116231.2|refseq:XP_005250712.1|refseq:XP_011514948.1|ensembl:ENSG00000146842(gene)|ensembl:ENST00000397622(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019176	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:LJ052UMkTP09EJVErI5qnsGxmJs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96S66	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96S52	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96R06	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96QK1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96KC8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96KA5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96K37	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-720094|uniprotkb:Q8NBQ2|uniprotkb:Q96JV7|ensembl:ENSP00000470652	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:s35e1_human(display_long)|uniprotkb:SLC35E1(gene name)|psi-mi:SLC35E1(display_short)|uniprotkb:PSEC0038(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_079157.3|ensembl:ENSG00000127526(gene)|ensembl:ENST00000595753(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004853(Protein of unknown function DUF250)|go:"GO:0015297"(antiporter activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:UelDuXaGT2mBsXghGzSX5aKisj89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96JJ7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96JB2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2807756|ensembl:ENSP00000258654|uniprotkb:Q5VT70|uniprotkb:B2RAW5|uniprotkb:Q9BZ92|uniprotkb:Q8IXX4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog3_human(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Vesicle-docking protein SEC34 homolog(gene name synonym)|uniprotkb:p94(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000136152(gene)|ensembl:ENST00000349995(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR007265(Sec34-like protein)|mint:Q96JB2|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_113619.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:P3sc7TLrhgqNPIh7VYpmsoIhSrE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96ER3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96DZ1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96D53	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96CP6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1384139|uniprotkb:A6NKY7|uniprotkb:Q8NC77|uniprotkb:Q9P1Z5|ensembl:ENSP00000441032	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:astra_human(display_long)|uniprotkb:GRAMD1A(gene name)|psi-mi:GRAMD1A(display_short)|uniprotkb:KIAA1533(gene name synonym)|uniprotkb:GRAM domain-containing protein 1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001306964.1|refseq:NP_001129671.1|refseq:NP_065946.2|refseq:NP_001306963.1|refseq:NP_001306965.1|ensembl:ENSG00000089351(gene)|ensembl:ENST00000317991(transcript)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|mint:Q96CP6	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:S7fzTVbf+LB0tpV7JvPZzpcs8709606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96CN4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96AQ6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96AG4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96A65	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q96A33	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q969Z0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-702328|uniprotkb:O14710|uniprotkb:Q53GI8|uniprotkb:Q8NDM4|uniprotkb:Q9BUC6|uniprotkb:Q9Y2F6|uniprotkb:A4D2L2|uniprotkb:A4D2L3|uniprotkb:D3DVL5|uniprotkb:D3DVL6|ensembl:ENSP00000258770|ensembl:ENSP00000420597	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:fakd4_human(display_long)|uniprotkb:Transforming growth factor beta regulator 4(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 2(gene name synonym)|uniprotkb:TBRG4(gene name)|psi-mi:TBRG4(display_short)|uniprotkb:CPR2(gene name synonym)|uniprotkb:FASTKD4(gene name synonym)|uniprotkb:KIAA0948(gene name synonym)|uniprotkb:Protein TBRG4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004740.2|refseq:NP_112162.1|refseq:NP_954573.1|ensembl:ENSG00000136270(gene)|ensembl:ENST00000258770(transcript)|ensembl:ENST00000494076(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090615"(mitochondrial mRNA processing)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q969Z0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2maj6VmOPUpSw5F+xJG2kfNKAc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q969N2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92990	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-726150|uniprotkb:Q9BVE8|uniprotkb:Q5VVC3|ensembl:ENSP00000359385	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:glmn_human(display_long)|uniprotkb:FAP68(gene name synonym)|uniprotkb:FKBP-associated protein(gene name synonym)|uniprotkb:FK506-binding protein-associated protein(gene name synonym)|uniprotkb:GLMN(gene name)|psi-mi:GLMN(display_short)|uniprotkb:FAP48(gene name synonym)|uniprotkb:VMGLOM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_444504.1|refseq:XP_011538848.1|refseq:NP_001306612.1|ensembl:ENSG00000174842(gene)|ensembl:ENST00000370360(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005171"(hepatocyte growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|interpro:IPR013877(Protein of unknown function DUF1760, fungi)|interpro:IPR019516|rcsb pdb:4F52|reactome:R-HSA-983168|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ZpLZbiPwlYDPX8C767kVrbKmEmo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92973	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92945	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92820	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3045534|ensembl:ENSP00000260118	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92621	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q92543	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-728232|ensembl:ENSP00000265909|uniprotkb:E9PKB9|uniprotkb:Q8IV55	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:snx19_human(display_long)|uniprotkb:SNX19(gene name)|psi-mi:SNX19(display_short)|uniprotkb:KIAA0254(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000120451(gene)|ensembl:ENST00000265909(transcript)|refseq:NP_055573.2|refseq:NP_001334847.1|refseq:NP_001334848.1|refseq:NP_001334849.1|refseq:NP_001334850.1|refseq:NP_001334851.1|refseq:NP_001334852.1|refseq:NP_001334853.1|refseq:NP_001334854.1|refseq:NP_001334855.1|refseq:NP_001334856.1|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0030073"(insulin secretion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1990502"(dense core granule maturation)|interpro:IPR001683(Phox-like)|interpro:IPR003114(PX-associated)|interpro:IPR013937(Sorting nexin, C-terminal)|interpro:IPR034908|interpro:IPR036871|interpro:IPR037909	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:K3NS39vRx+FYSZXGpylwf32l0ug9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WXD5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WWC4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WVX9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WVM8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WUY1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1170414|uniprotkb:Q8NBN2|uniprotkb:Q9NYI2|uniprotkb:B2RDN6|intact:EBI-2563242|ensembl:ENSP00000338607	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:them6_human(display_long)|uniprotkb:THEM6(gene name)|psi-mi:THEM6(display_short)|uniprotkb:C8orf55(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSCD75(gene name synonym)|uniprotkb:Thioesterase superfamily member 6(gene name synonym)|uniprotkb:PSEC0098(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_057731.1|ensembl:ENSG00000130193(gene)|ensembl:ENST00000336138(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR029069	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:VCZRUm2WiwLdWnKB8jTuOvLy+4A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8WUM0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8TEM1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8TCG1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8TC07	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8NI60	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8NEW0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1043569|uniprotkb:Q8TCH2|ensembl:ENSP00000350278|ensembl:ENSP00000359130|uniprotkb:B2R949|uniprotkb:D3DT61	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:znt7_human(display_long)|uniprotkb:SLC30A7(gene name)|psi-mi:SLC30A7(display_short)|uniprotkb:ZNT7(gene name synonym)|uniprotkb:ZNTL2(gene name synonym)|uniprotkb:Znt-like transporter 2(gene name synonym)|uniprotkb:Solute carrier family 30 member 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000162695(gene)|ensembl:ENST00000357650(transcript)|ensembl:ENST00000370112(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006829"(zinc ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|reactome:R-HSA-264876|reactome:R-HSA-435368|go:"GO:0032119"(sequestering of zinc ion)|refseq:NP_001138356.1|refseq:NP_598003.2|refseq:XP_016855889.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/okPwOjluCDoM8a5uHoixAyRc8E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8NCR1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-16812810	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q8ncr1_human(display_long)|uniprotkb:VPS53(gene name)|psi-mi:VPS53(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0000938"(GARP complex)|go:"GO:0005829"(cytosol)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR038260|interpro:IPR039766	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5KDhZp7Q00KieYEvTMEq6Qzlxsw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8NBU5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2511886|ensembl:ENSP00000339016|ensembl:ENSP00000339017|ensembl:ENSP00000489353|ensembl:ENSP00000489455|ensembl:ENSP00000506333|uniprotkb:Q6P4B9|uniprotkb:Q969Y3|uniprotkb:Q8WYR9|uniprotkb:Q8N3G1|uniprotkb:Q6DKG1|uniprotkb:D3DR26	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atad1_human(display_long)|uniprotkb:ATAD1(gene name)|psi-mi:ATAD1(display_short)|uniprotkb:Thorase(gene name synonym)|uniprotkb:FNP001(orf name)|uniprotkb:ATPase family AAA domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000138138(gene)|ensembl:ENSG00000283024(gene)|ensembl:ENST00000308448(transcript)|ensembl:ENST00000328142(transcript)|ensembl:ENST00000634773(transcript)|ensembl:ENST00000634970(transcript)|ensembl:ENST00000680024(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|reactome:R-HSA-9603798|refseq:NP_116199.2|refseq:NP_001308896.1|refseq:XP_005270309.1|refseq:XP_016872336.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:IGkIH4udjuFoshP9hMDDK0ARNOg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8N766	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8N5G2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8N3U4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sJ813DVkungq+1f1rgugDN2gsn09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8N1F7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:pkk5pooUC4yQShpqjiwNLddfy149606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8IXB1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q8IV08	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|ensembl:ENSP00000348901|ensembl:ENSP00000386293|ensembl:ENSP00000386938|ensembl:ENSP00000387022|ensembl:ENSP00000387050	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pld3_human(display_long)|uniprotkb:Choline phosphatase 3(gene name synonym)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D3(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001278240.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:NP_001026866.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|ensembl:ENSG00000105223(gene)|ensembl:ENST00000356508(transcript)|ensembl:ENST00000409281(transcript)|ensembl:ENST00000409419(transcript)|ensembl:ENST00000409587(transcript)|ensembl:ENST00000409735(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002376"(immune system process)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:XP_006723185.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q86Y56	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-719966|uniprotkb:Q69YL1|uniprotkb:Q96FI9|uniprotkb:Q9NX75|ensembl:ENSP00000297440	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:daaf5_human(display_long)|uniprotkb:DNAAF5(gene name)|psi-mi:DNAAF5(display_short)|uniprotkb:HEAT repeat-containing protein 2(gene name synonym)|uniprotkb:HEATR2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060272.3|ensembl:ENSG00000164818(gene)|ensembl:ENST00000297440(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0005737"(cytoplasm)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|mint:Q86Y56	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5AmIkT2NW1/GyC8udQmrI5hRAsU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q86VP6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q7Z4Q2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q7RTS9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2871106|uniprotkb:A8K5I8|uniprotkb:Q3ZTS8|uniprotkb:Q9NPU7|uniprotkb:Q6P2P5|uniprotkb:B4DKI7|uniprotkb:Q9BVE9|uniprotkb:B2RCF9|uniprotkb:Q8N2M0|ensembl:ENSP00000269445	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dym_human(display_long)|uniprotkb:DYM(gene name)|psi-mi:DYM(display_short)|uniprotkb:Dyggve-Melchior-Clausen syndrome protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060123.3|ensembl:ENSG00000141627(gene)|ensembl:ENST00000269445(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0060348"(bone development)|interpro:IPR019142	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4o4oPqyjY7dKe5VV26gDM6rXIFM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q7L1Q6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6YHU6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2824523|uniprotkb:Q3KR04|uniprotkb:Q53RC6|uniprotkb:Q6ZU38|uniprotkb:Q9H6W7|uniprotkb:Q6YHU2|uniprotkb:Q9C096|uniprotkb:Q96I88|uniprotkb:Q8TAU8|uniprotkb:Q9H6U0|uniprotkb:B7WNS6|uniprotkb:Q53TB2|uniprotkb:A8K1V8|intact:EBI-3213832|uniprotkb:Q9BZF7|ensembl:ENSP00000385995|ensembl:ENSP00000386088|uniprotkb:Q8IY32	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:thada_human(display_long)|uniprotkb:THADA(gene name)|psi-mi:THADA(display_short)|uniprotkb:GITA(gene name synonym)|uniprotkb:KIAA1767(gene name synonym)|uniprotkb:Gene inducing thyroid adenomas protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001332854.1|ensembl:ENSG00000115970(gene)|ensembl:ENST00000405006(transcript)|ensembl:ENST00000405975(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019442|rcsb pdb:5T6Y|reactome:R-HSA-6782315|refseq:XP_006712128.1|refseq:NP_001077422.1|refseq:NP_071348.3|refseq:NP_001258572.1|refseq:NP_001258573.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HLP/DNXyeZkkWzwOjvl/6A+U6eU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6UWP7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10254507|uniprotkb:Q8N1Q7|uniprotkb:A6H8Z7|ensembl:ENSP00000310551	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:lclt1_human(display_long)|uniprotkb:LCLAT1(gene name)|psi-mi:LCLAT1(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 8(gene name synonym)|uniprotkb:AGPAT8(gene name synonym)|uniprotkb:ALCAT1(gene name synonym)|uniprotkb:"Acyl-CoA:lysocardiolipin acyltransferase 1"(gene name synonym)|uniprotkb:LYCAT(gene name synonym)|uniprotkb:UNQ1849/PRO3579(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_016859235.1|refseq:NP_001002257.1|refseq:NP_872357.2|refseq:XP_005264301.1|refseq:XP_005264302.1|refseq:NP_001291374.1|refseq:XP_011531043.1|refseq:XP_011531044.1|refseq:XP_011531045.1|ensembl:ENSG00000172954(gene)|ensembl:ENST00000309052(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0036149"(phosphatidylinositol acyl-chain remodeling)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|mint:Q6UWP7|reactome:R-HSA-1482798|reactome:R-HSA-1483166	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:gZmAvDRqPstHwWE4V+Pt8aawdIc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6PML9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006336.3|ensembl:ENSG00000014824(gene)|ensembl:ENST00000264451(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|rcsb pdb:2ENK	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6P582	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2558548|uniprotkb:Q8WVB2|uniprotkb:Q3SWV8|ensembl:ENSP00000311500	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mzt2a_human(display_long)|uniprotkb:FAM128A(gene name synonym)|uniprotkb:MOZART2A(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A(gene name synonym)|uniprotkb:MZT2A(gene name)|psi-mi:MZT2A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001078834.1|ensembl:ENSG00000173272(gene)|ensembl:ENST00000309451(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|interpro:IPR024332|rcsb pdb:6X0V|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:dCqJOdxX0GGsuNM2rTxgktV4u9s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6P4Q7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11918149|ensembl:ENSP00000366275|uniprotkb:B7Z1U0|uniprotkb:C7SQM3|uniprotkb:C7SQM4|uniprotkb:C7SQM5|uniprotkb:Q53RE5|uniprotkb:Q9H9G3|uniprotkb:Q9HCI0|uniprotkb:Q9NRN1	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cnnm4_human(display_long)|uniprotkb:CNNM4(gene name)|psi-mi:CNNM4(display_short)|uniprotkb:ACDP4(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 4(gene name synonym)|uniprotkb:Cyclin-M4(gene name synonym)|uniprotkb:KIAA1592(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000158158(gene)|ensembl:ENST00000377075(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007601"(visual perception)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050896"(response to stimulus)|go:"GO:0055065"(metal ion homeostasis)|go:"GO:0070166"(enamel mineralization)|interpro:IPR000595(Cyclic nucleotide-binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030425"(dendrite)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR018490|interpro:IPR044751|rcsb pdb:6G52|rcsb pdb:6RS2|refseq:NP_064569.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sdYQzd8X3Gz9Okurljb9g+Homt89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6P3X3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1057046|uniprotkb:A6NKJ0|uniprotkb:Q96SS5|uniprotkb:Q9BVF1|uniprotkb:Q9NWR4|uniprotkb:Q9NXG4|ensembl:ENSP00000313953	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ttc27_human(display_long)|uniprotkb:TTC27(gene name)|psi-mi:TTC27(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001180438.1|refseq:NP_060205.3|ensembl:ENSG00000018699(gene)|ensembl:ENST00000317907(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR044244|mint:Q6P3X3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:LvE8UTgFaNjAZEkxCnmPTr/YP+Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6P1M0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6NXR4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-4566107|uniprotkb:D3DSV7|uniprotkb:Q96IM2|uniprotkb:Q9H5N4|ensembl:ENSP00000353971|ensembl:ENSP00000411169|ensembl:ENSP00000478396	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tti2_human(display_long)|uniprotkb:TTI2(gene name)|psi-mi:TTI2(display_short)|uniprotkb:C8orf41(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001095871.1|refseq:NP_079391.2|refseq:NP_001252510.1|ensembl:ENSG00000129696(gene)|ensembl:ENST00000360742(transcript)|ensembl:ENST00000431156(transcript)|ensembl:ENST00000613904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0070209"(ASTRA complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018870|go:"GO:0005813"(centrosome)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:CK+55nt5IJEfNNFXWqo9MPSA3bo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q6NUQ1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q68DH5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-20858131|ensembl:ENSP00000296603|uniprotkb:B3KRB6|uniprotkb:Q9NTC7	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:lmbd2_human(display_long)|uniprotkb:LMBRD2(gene name)|psi-mi:LMBRD2(display_short)|uniprotkb:LMBR1 domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000164187(gene)|ensembl:ENST00000296603(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071875"(adrenergic receptor signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|mint:Q68DH5|refseq:NP_001007528.1|refseq:XP_011512464.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:q2WB24Dd8SLHl38AcRDvDE/k8zs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q68D27	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21261767	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q68d27_human(display_long)|uniprotkb:DKFZp686B20267(gene name)|psi-mi:DKFZp686B20267(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|refseq:NP_001280202.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:THsbOklraRO84LO3t3QenHcGLRY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q63HN8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5VV42	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5TB53	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21260364|ensembl:ENSP00000401152	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q5tb53_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0016021"(integral component of membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensembl:ENSG00000077147(gene)|ensembl:ENST00000443638(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:T1DWVoePJSFkdgudFKdtzv/VaCg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5TAQ9	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5T4S7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8Iown8oj965YAir+95+3om5+1YM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5SZE2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262890|ensembl:ENSP00000394012	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q5sze2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000143418(gene)|ensembl:ENST00000457392(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ka5Rf62LvM6VKgqeYwzYWklPFHc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5JYR7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262879|ensembl:ENSP00000362735	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q5jyr7_human(display_long)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008814(Ribophorin II)|ensembl:ENSG00000118705(gene)|ensembl:ENST00000373632(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:XtgQttct6NCg4alvIHMvEzDw4Ak9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5JSD2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5HYI8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000144840(gene)|ensembl:ENST00000273375(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:1903059"(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|go:"GO:0050821"(protein stabilization)|refseq:NP_776186.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5H8A4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11724298|uniprotkb:B4DKC7|uniprotkb:Q2TAK5|uniprotkb:Q6UX31|uniprotkb:Q7L5Y4|uniprotkb:Q8N866|uniprotkb:Q8NCC9|uniprotkb:Q96SY9|uniprotkb:Q9BVT7|uniprotkb:Q9NXG5|ensembl:ENSP00000415203	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pigg_human(display_long)|uniprotkb:PIGG(gene name)|psi-mi:PIGG(display_short)|uniprotkb:GPI7(gene name synonym)|uniprotkb:GPI7 homolog(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class G protein(gene name synonym)|uniprotkb:UNQ1930/PRO4405(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_060203.3|refseq:NP_001120650.1|refseq:NP_001275980.1|refseq:NP_001275981.1|refseq:NP_001275984.1|refseq:NP_001275986.1|ensembl:ENST00000310340|ensembl:ENSP00000311750|ensembl:ENSP00000372494|ensembl:ENSP00000415203|ensembl:ENST00000503111|ensembl:ENSP00000426002|ensembl:ENST00000383028|ensembl:ENSG00000174227(gene)|ensembl:ENST00000453061(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0016780"(phosphotransferase activity, for other substituted phosphate groups)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0051267"(CP2 mannose-ethanolamine phosphotransferase activity)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR037674|interpro:IPR039527|mint:Q5H8A4|reactome:R-HSA-162710	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:pyq+Yfj4SCmVo17n62cZUT2YzJo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q5BJH7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q53GQ0	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q3ZCQ8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q32Q12	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11897132|ensembl:ENSP00000451932	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q32q12_human(display_long)|uniprotkb:NME1-NME2(gene name)|psi-mi:NME1-NME2(display_short)|uniprotkb:hCG_2001850(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000011052(gene)|ensembl:ENST00000555572(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:F9Z+VsBFIAci0CnyPOHlWo7SinY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q29RF7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q16637	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15758	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15645	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15629	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1788852|uniprotkb:B4E0K2|ensembl:ENSP00000262213	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tram1_human(display_long)|uniprotkb:TRAM1(gene name)|psi-mi:TRAM1(display_short)|uniprotkb:TRAM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055109.1|refseq:NP_001304733.1|refseq:NP_001304734.1|dip:DIP-45978N|ensembl:ENSG00000067167(gene)|ensembl:ENST00000262213(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016447(Translocation associated membrane protein)|mint:Q15629|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:MsD+t4fSxQllDp5wobRI5mAL5+49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15392	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-5457558|uniprotkb:B7Z817|ensembl:ENSP00000360316|ensembl:ENSP00000416585|uniprotkb:D3DQ51|uniprotkb:Q9HBA8|intact:EBI-10964490	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dhc24_human(display_long)|uniprotkb:DHCR24(gene name)|psi-mi:DHCR24(display_short)|uniprotkb:KIAA0018(gene name synonym)|uniprotkb:24-dehydrocholesterol reductase(gene name synonym)|uniprotkb:Diminuto/dwarf1 homolog(gene name synonym)|uniprotkb:Seladin-1(gene name synonym)|uniprotkb:3-beta-hydroxysterol Delta-24-reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000116133(gene)|ensembl:ENST00000371269(transcript)|ensembl:ENST00000436604(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0050614"(delta24-sterol reductase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061024"(membrane organization)|go:"GO:0071949"(FAD binding)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318|interpro:IPR040165|go:"GO:0005737"(cytoplasm)|mint:Q15392|reactome:R-HSA-6807047|reactome:R-HSA-6807062|refseq:NP_055577.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kg8bxZHxFFTUmvP9UQMeVFRNWQM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15386	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15155	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15043	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952|ensembl:ENSP00000370635	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011542780.1|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_016868783.1|refseq:XP_016868784.1|ensembl:ENSG00000104635(gene)|ensembl:ENST00000289952(transcript)|ensembl:ENST00000381237(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015296"("anion:cation symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033212"(iron import into cell)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055071"(manganese ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0098739"(import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|mint:Q15043|reactome:R-HSA-442380	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15021	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q15006	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14974	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14746	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-389449|uniprotkb:Q86U99|ensembl:ENSP00000355629	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog2_human(display_long)|uniprotkb:COG2(gene name)|psi-mi:COG2(display_short)|uniprotkb:LDLC(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:Low density lipoprotein receptor defect C-complementing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_031383.1|refseq:NP_001138508.1|ensembl:ENSG00000135775(gene)|ensembl:ENST00000366669(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR009316(COG complex component, COG2)|interpro:IPR024602|interpro:IPR024603|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:LikqIIuX72shymiuUF977aVlfpE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14571	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2831342|uniprotkb:O94773|ensembl:ENSP00000370744	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:itpr2_human(display_long)|uniprotkb:ITPR2(gene name)|psi-mi:ITPR2(display_short)|uniprotkb:IP3 receptor isoform 2(gene name synonym)|uniprotkb:Type 2 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000123104(gene)|ensembl:ENST00000381340(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_002214.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:godRDJb6vyJG454Heg9JZhLarLc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14435	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10697820|uniprotkb:Q7Z476|uniprotkb:Q53TG9|ensembl:ENSP00000376465	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:galt3_human(display_long)|uniprotkb:GALNT3(gene name)|psi-mi:GALNT3(display_short)|uniprotkb:Polypeptide GalNAc transferase 3(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 3(gene name synonym)|uniprotkb:"UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004473.2|refseq:XP_005246506.1|refseq:XP_011509231.1|ensembl:ENSG00000115339(gene)|ensembl:ENST00000392701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004653"(polypeptide N-acetylgalactosaminyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0018243"(protein O-linked glycosylation via threonine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|reactome:R-HSA-190372|reactome:R-HSA-5083625|reactome:R-HSA-913709|refseq:XP_016859259.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ctuWH3RUp0sYoXZl0G0gyZoQ8609606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14257	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14232	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|uniprotkb:B4DGX0|ensembl:ENSP00000416250	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ei2ba_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001405.1|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000111361(gene)|ensembl:ENST00000424014(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q14165	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1046466|ensembl:ENSP00000228506	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q13885	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	intact:EBI-20649665	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	-	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tuba3c_tuba3d_human(display_short)|psi-mi:EBI-20649665(display_long)|intact:TUBA3C/TUBA3D(author assigned name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	uniprotkb:P0DPH7(set member)|uniprotkb:P0DPH8(set member)|uniprotkb:Q13748(see-also)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q13576	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q13438	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q13144	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q12797	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q07065	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q00325	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P83436	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P78527	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P62318	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P62316	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P62314	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P62306	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P62304	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P61073	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P60604	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P58511	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1051936|ensembl:ENSP00000382231|ensembl:ENSP00000382234|ensembl:ENSP00000498771|ensembl:ENSP00000499160	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sim11_human(display_long)|uniprotkb:SMIM11(gene name)|psi-mi:SMIM11(display_short)|uniprotkb:C21orf51(gene name synonym)|uniprotkb:FAM165B(gene name synonym)|uniprotkb:SMIM11A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_478062.1|refseq:NP_001300621.1|ensembl:ENSG00000205670(gene)|ensembl:ENST00000399292(transcript)|ensembl:ENST00000399295(transcript)|ensembl:ENST00000474455(transcript)|ensembl:ENST00000652570(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028023|interpro:IPR042125|refseq:XP_016883692.1|refseq:XP_016883693.1|refseq:XP_016883694.1|refseq:XP_016883886.1|refseq:XP_016883887.1|refseq:XP_016883888.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ViyD+bLK427s3oVmSJU6qd+EChw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P57678	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P56385	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P56381	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3904845|uniprotkb:E1P5H6|uniprotkb:B2RDD0|uniprotkb:Q53XU6|ensembl:ENSP00000243997|ensembl:ENSP00000379019|ensembl:ENSP00000379023	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp5e_human(display_long)|uniprotkb:ATP5F1E(gene name)|psi-mi:ATP5F1E(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATP5E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_008817.1|ensembl:ENSG00000124172(gene)|ensembl:ENST00000243997(transcript)|ensembl:ENST00000395659(transcript)|ensembl:ENST00000395663(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:b8qOktspV0v7Gs9uQPpLHf6kLqI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P56192	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|uniprotkb:B3KVK7|ensembl:ENSP00000262027	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|reactome:R-HSA-379716|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|refseq:NP_004981.2|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000166986(gene)|ensembl:ENST00000262027(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|dip:DIP-38164N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P55072	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P55060	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P55040	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P54709	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P53621	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P53618	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P52701	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P52429	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P51648	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P51617	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P51571	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P51148	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P50402	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P48444	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P48047	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P46977	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P42704	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P42695	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P42345	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P40855	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P39880	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P38606	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P37268	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-714550|intact:EBI-1058542|uniprotkb:Q96GT0|ensembl:ENSP00000220584|ensembl:ENSP00000480828|ensembl:ENSP00000481481|uniprotkb:B3KQ95|uniprotkb:B4DJE5|uniprotkb:B4DT56|uniprotkb:B7Z1J3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:fdft_human(display_long)|uniprotkb:Farnesyl-diphosphate farnesyltransferase(gene name synonym)|uniprotkb:"FPP:FPP farnesyltransferase"(gene name synonym)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:Farnesyl-diphosphate farnesyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENST00000618539(transcript)|refseq:NP_004453.3|ensembl:ENSG00000079459(gene)|ensembl:ENST00000220584(transcript)|ensembl:ENST00000615631(transcript)|rcsb pdb:3LEE|rcsb pdb:3Q2Z|rcsb pdb:3Q30|rcsb pdb:3V66|rcsb pdb:3VJ8|rcsb pdb:3VJ9|rcsb pdb:3VJA|rcsb pdb:3VJB|rcsb pdb:3VJC|rcsb pdb:3WC9|rcsb pdb:3WCD|rcsb pdb:3WCF|rcsb pdb:3WCH|rcsb pdb:3WCI|rcsb pdb:3WCJ|rcsb pdb:3WCL|rcsb pdb:3WCM|rcsb pdb:3WEF|rcsb pdb:3WEG|rcsb pdb:3WEH|rcsb pdb:3WEI|rcsb pdb:3WEJ|rcsb pdb:3WEK|rcsb pdb:3WSA|rcsb pdb:6PYJ|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|rcsb pdb:3ASX|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051996"(squalene synthase activity)|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR019845|interpro:IPR033904|interpro:IPR044844|mint:P37268|rcsb pdb:1EZF|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_001274673.1|refseq:NP_001274674.1|refseq:NP_001274676.1|refseq:NP_001274677.1|refseq:NP_001274678.1|refseq:NP_001274679.1|refseq:NP_001274680.1|refseq:NP_001274685.1|refseq:XP_016868706.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P37198	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P36542	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P35998	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P35606	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P33527	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3911547|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4|ensembl:ENSP00000382342|ensembl:ENSP00000483316	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:"Leukotriene C(4) transporter"(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004987.2|ensembl:ENSG00000103222(gene)|ensembl:ENSG00000278183(gene)|ensembl:ENST00000399410(transcript)|ensembl:ENST00000621144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015420"(ABC-type vitamin B12 transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034040"(ATPase-coupled lipid transmembrane transporter activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0034775"(glutathione transmembrane transport)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0099039"(sphingolipid translocation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0140359"(ABC-type transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905039"(carboxylic acid transmembrane transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292("Multi drug resistance-associated protein (MRP)")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-196741|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-189483	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P30049	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P30048	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P28340	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P27824	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P26641	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P25705	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P24539	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P23258	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-302589|ensembl:ENSP00000251413|uniprotkb:Q9BW59|uniprotkb:Q53X79	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|interpro:IPR017975|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000131462(gene)|ensembl:ENST00000251413(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|go:"GO:0005814"(centriole)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|refseq:NP_001061.2|dip:DIP-29890N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P20674	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P20020	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P19367	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-713162|uniprotkb:Q5VTC3|uniprotkb:Q96HC8|uniprotkb:Q9NNZ4|uniprotkb:O43443|uniprotkb:O43444|uniprotkb:O75574|uniprotkb:Q9NNZ5|uniprotkb:E9PCK0|ensembl:ENSP00000352398	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:hxk1_human(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:HK1(gene name)|psi-mi:HK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000179.2|refseq:NP_277031.1|refseq:NP_277032.1|refseq:NP_277033.1|refseq:NP_277035.2|refseq:XP_011538034.1|refseq:NP_001309293.1|dip:DIP-56245N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P19367|rcsb pdb:1CZA|rcsb pdb:1DGK|rcsb pdb:1HKB|rcsb pdb:1HKC|rcsb pdb:1QHA|rcsb pdb:4FOE|rcsb pdb:4FOI|rcsb pdb:4FPA|rcsb pdb:4FPB|reactome:R-HSA-5619056|reactome:R-HSA-70171|rcsb pdb:4F9O|ensembl:ENSG00000156515(gene)|ensembl:ENST00000359426(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:cvNEGlnCikx3E17kNYTSI39EUfU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P18859	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P18031	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-968788|ensembl:ENSP00000360683|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000196396(gene)|ensembl:ENST00000371621(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097443"(sorting endosome)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1AAX|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2NT7|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2NTA|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2QBP|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2QBS|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2VEU|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2F6Z|rcsb pdb:2ZMM|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:6OMY|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:3EB1|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:7KEN|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MM1|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|rcsb pdb:6PFW|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QDV|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P17987	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P17980	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P16615	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P13073	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P12277	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P12004	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P07858	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P06576	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P05026	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P05023	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P04843	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P04350	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P04035	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P03928	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:YP_003024030.1|ensembl:ENSG00000228253(gene)|ensembl:ENST00000361851(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P02788	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:P02786	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95831	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95490	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|intact:EBI-28986872|ensembl:ENSP00000359752|ensembl:ENSP00000359763	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_036434.1|ensembl:ENST00000319517|ensembl:ENSP00000322270|ensembl:ENST00000359929|ensembl:ENSP00000353006|ensembl:ENST00000370713|ensembl:ENSP00000359748|ensembl:ENST00000370715|ensembl:ENSP00000359750|ensembl:ENSP00000359752|ensembl:ENST00000370723|ensembl:ENSP00000359758|ensembl:ENST00000370725|ensembl:ENSP00000359760|ensembl:ENSP00000359763|ensembl:ENST00000370730|ensembl:ENSP00000359765|ensembl:ENST00000674393|ensembl:ENSP00000501431|ensembl:ENST00000674419|ensembl:ENSP00000501462|refseq:XP_005270723.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114(gene)|ensembl:ENST00000370717(transcript)|ensembl:ENST00000370728(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0009617"(response to bacterium)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016524"(latrotoxin receptor activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031240|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95470	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95347	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95292	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O95202	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1052895|uniprotkb:Q9UF65|uniprotkb:B4DED2|ensembl:ENSP00000305653	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:letm1_human(display_long)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)|uniprotkb:LETM1(gene name)|psi-mi:LETM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_036450.1|ensembl:ENSG00000168924(gene)|ensembl:ENST00000302787(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042407"(cristae formation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|reactome:R-HSA-8949215|reactome:R-HSA-9013408	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mDxqXWqmgCjbaZLz4JqteqjDCik9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O94905	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O94874	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1048088|intact:EBI-2798769|uniprotkb:Q8N765|uniprotkb:Q9NTQ0|uniprotkb:A0PJ53|uniprotkb:B4DJ57|uniprotkb:C0H5X5|ensembl:ENSP00000358283	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ufl1_human(display_long)|uniprotkb:UFL1(gene name)|psi-mi:UFL1(display_short)|uniprotkb:E3 UFM1-protein transferase 1(gene name synonym)|uniprotkb:KIAA0776(gene name synonym)|uniprotkb:Novel LZAP-binding protein(gene name synonym)|uniprotkb:RCAD(gene name synonym)|uniprotkb:Regulator of C53/LZAP and DDRGK1(gene name synonym)|uniprotkb:NLBP(gene name synonym)|uniprotkb:MAXER(gene name synonym)|uniprotkb:Multiple alpha-helix protein located at ER(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056138.1|ensembl:ENSG00000014123(gene)|ensembl:ENST00000369278(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016570"(histone modification)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061666"(UFM1 ligase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR018611|mint:O94874|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wiJotyDNle7GoYzFkOif0TFNr2w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O94829	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O94822	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O76071	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75964	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75947	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75477	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75396	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75306	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75155	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O75027	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O60858	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-9867345|uniprotkb:B2RB49|uniprotkb:Q5UBW0|uniprotkb:Q5W0U8|uniprotkb:Q5W0U9|uniprotkb:Q9BQ47|uniprotkb:Q9C021|ensembl:ENSP00000367424|ensembl:ENSP00000399206|ensembl:ENSP00000412943	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tri13_human(display_long)|uniprotkb:TRIM13(gene name)|psi-mi:TRIM13(display_short)|uniprotkb:LEU5(gene name synonym)|uniprotkb:RFP2(gene name synonym)|uniprotkb:RNF77(gene name synonym)|uniprotkb:B-cell chronic lymphocytic leukemia tumor suppressor Leu5(gene name synonym)|uniprotkb:Leukemia-associated protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor RFP2(gene name synonym)|uniprotkb:RING finger protein 77(gene name synonym)|uniprotkb:Ret finger protein 2(gene name synonym)|uniprotkb:Tripartite motif-containing protein 13(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001007279.1|refseq:NP_005789.2|refseq:NP_434698.1|refseq:NP_998755.1|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1902187"|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|reactome:R-HSA-901032|ensembl:ENSG00000204977(gene)|ensembl:ENST00000378182(transcript)|ensembl:ENST00000420995(transcript)|ensembl:ENST00000457662(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045087"(innate immune response)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:slO+9iGYn8qnnL4SYq7hmpfZOy09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O60762	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O60613	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1052797|uniprotkb:Q4GZG7|uniprotkb:Q8WU00|uniprotkb:Q9BS64|uniprotkb:Q9GZW0|uniprotkb:Q9NR01|ensembl:ENSP00000328729|uniprotkb:A0A0B4J1S4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sep15_human(display_long)|uniprotkb:SELENOF(gene name)|psi-mi:SELENOF(display_short)|uniprotkb:15 kDa selenoprotein(gene name synonym)|uniprotkb:SEP15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004252.2|refseq:NP_976086.1|mint:O60613|interpro:IPR039992|ensembl:ENSG00000183291(gene)|ensembl:ENST00000331835(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR014912(Sep15/SelM redox)|interpro:IPR036249|interpro:IPR038219	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:O+C59EK6dpYLDbHWrJT10RtGus89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O60447	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-852291|uniprotkb:A6NKX8|uniprotkb:Q9H1Y9|uniprotkb:B9A6J0|intact:EBI-28983653|ensembl:ENSP00000359356	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:evi5_human(display_long)|uniprotkb:Neuroblastoma stage 4S gene protein(gene name synonym)|uniprotkb:EVI5(gene name)|psi-mi:EVI5(display_short)|uniprotkb:NB4S(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_005656.4|ensembl:ENSP00000359356|ensembl:ENST00000540033|ensembl:ENSP00000440826|refseq:NP_001295177.1|dip:DIP-38024N|ensembl:ENSG00000067208(gene)|ensembl:ENST00000370331(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:EyooNakM1gos/ADyryAHwuQPhZk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O43909	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1754679|uniprotkb:O00225|uniprotkb:Q53XT3|uniprotkb:D3DST8|ensembl:ENSP00000220562	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:extl3_human(display_long)|uniprotkb:EXTL3(gene name)|psi-mi:EXTL3(display_short)|uniprotkb:EXTL1L(gene name synonym)|uniprotkb:EXTR1(gene name synonym)|uniprotkb:KIAA0519(gene name synonym)|uniprotkb:Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:Putative tumor suppressor protein EXTL3(gene name synonym)|uniprotkb:Multiple exostosis-like protein 3(gene name synonym)|uniprotkb:Hereditary multiple exostoses gene isolog(gene name synonym)|uniprotkb:EXT-related protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011542742.1|refseq:NP_001431.1|ensembl:ENSG00000012232(gene)|ensembl:ENST00000220562(transcript)|go:"GO:0001888"(glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0046872"(metal ion binding)|interpro:IPR004263(Exostosin-like)|interpro:IPR015338(EXTL2, alpha-1,4-N-acetylhexosaminyltransferase)|interpro:IPR029044|interpro:IPR040911|reactome:R-HSA-381038	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:2G4jJX6fU7NM/2Q7itA3CTDW1gU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O43592	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15397	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15270	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15269	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15260	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15120	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3935937|uniprotkb:Q9BWR7|uniprotkb:O00516|uniprotkb:Q5VUD4|uniprotkb:Q9BSV7|uniprotkb:O15106|uniprotkb:Q5VUD3|intact:EBI-28988552|ensembl:ENSP00000360761|ensembl:ENSP00000438919	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:plcb_human(display_long)|uniprotkb:AGPAT2(gene name)|psi-mi:AGPAT2(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 2(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001012745.1|refseq:NP_006403.2|ensembl:ENST00000371694|ensembl:ENSP00000360759|ensembl:ENSP00000360761|ensembl:ENSP00000438919|ensembl:ENSG00000169692(gene)|ensembl:ENST00000371696(transcript)|ensembl:ENST00000538402(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-6798695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:quJFJpDvkJbjDx+PiTqRDpLfqzg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O15063	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-8796785|ensembl:ENSP00000299505|uniprotkb:Q2M3W4	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:grre1_human(display_long)|uniprotkb:GARRE1(gene name)|psi-mi:GARRE1(display_short)|uniprotkb:KIAA0355(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000166398(gene)|ensembl:ENST00000299505(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005829"(cytosol)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:1905762"(CCR4-NOT complex binding)|interpro:IPR031813|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|interpro:IPR043385|refseq:XP_005259501.1|refseq:NP_055501.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:I/Za29O3mRp12vCgPEFs6Xgjevo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14981	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1043840|uniprotkb:O43578|ensembl:ENSP00000265990|uniprotkb:B4E0W6	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:btaf1_human(display_long)|uniprotkb:BTAF1(gene name)|psi-mi:BTAF1(display_short)|uniprotkb:TAF172(gene name synonym)|uniprotkb:ATP-dependent helicase BTAF1(gene name synonym)|uniprotkb:TBP-associated factor 172(gene name synonym)|uniprotkb:"TAF(II)170"(gene name synonym)|uniprotkb:B-TFIID transcription factor-associated 170 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_003963.1|ensembl:ENSG00000095564(gene)|ensembl:ENST00000265990(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022707|interpro:IPR027417|interpro:IPR038718|interpro:IPR044078|mint:O14981	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:TUDUowqheA9/EO9RjuCwgwa6HY49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14980	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14975	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14967	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14787	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-431907|uniprotkb:O14655|intact:EBI-1053477|uniprotkb:Q6IN77|ensembl:ENSP00000407182|ensembl:ENSP00000468434	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:tnpo2_human(display_long)|uniprotkb:Karyopherin beta-2b(gene name synonym)|uniprotkb:TNPO2(gene name)|psi-mi:TNPO2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001129668.1|refseq:NP_001129667.1|refseq:NP_038461.2|ensembl:ENSG00000105576(gene)|ensembl:ENST00000425528(transcript)|ensembl:ENST00000592287(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:B+ZqD5TWiP/J6/ZwiM+39lO9E749606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14681	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-2339413|uniprotkb:Q9BUQ1|uniprotkb:A8K7D6|uniprotkb:B4DKL6|ensembl:ENSP00000278903|ensembl:ENSP00000484510	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ei24_human(display_long)|uniprotkb:EI24(gene name)|psi-mi:EI24(display_short)|uniprotkb:PIG8(gene name synonym)|uniprotkb:p53-induced gene 8 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011541371.1|refseq:NP_001277064.1|refseq:NP_004870.3|ensembl:ENSG00000149547(gene)|ensembl:ENST00000278903(transcript)|ensembl:ENST00000620753(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR009890(Etoposide-induced 2.4)|mint:O14681	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mb5BoJ3ithOKYe8mN+ZRB4UoltI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14654	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O14579	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00743	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00471	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00410	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00264	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00217	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:O00165	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:M0QZX5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21261668|ensembl:ENSP00000470834	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:m0qzx5_human(display_long)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000105135(gene)|ensembl:ENST00000598709(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR029035	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hXycrRCQFMdvAFb4dmK4T7Z6NM89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:K7EIH8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21259594|ensembl:ENSP00000464756	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:k7eih8_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000168259(gene)|ensembl:ENST00000590348(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/fSmMnrnj/XjslVdpKlrM2w3nqA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:I3L4P8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H6VRG2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258937	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h6vrg2_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:Keratin, type II cytoskeletal 1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005886"(plasma membrane)|go:"GO:0045095"(keratin filament)|interpro:IPR018039|interpro:IPR039008|interpro:IPR032449|interpro:IPR032444|interpro:IPR003054(Type II keratin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:PLuY4SY5eKZ1V/E2+/aEfMHIF9s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H3BV16	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21264870|ensembl:ENSP00000457908	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h3bv16_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000140990(gene)|ensembl:ENST00000570172(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0070469"(respirasome)|interpro:IPR019377|interpro:IPR039993	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/sfTdLokctzOx6u8xrN2rqwkslk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H3BQD2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21266761|ensembl:ENSP00000455720	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h3bqd2_human(display_long)|uniprotkb:METTL9(gene name)|psi-mi:METTL9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000197006(gene)|ensembl:ENST00000569290(transcript)|interpro:IPR007884(DREV methyltransferase)|interpro:IPR029063	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5VvfkxNPsqbyBY49mrCHQPP6ukA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H0YL12	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21259817|ensembl:ENSP00000453017	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h0yl12_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005759"(mitochondrial matrix)|ensembl:ENSG00000140374(gene)|ensembl:ENST00000560345(transcript)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR029035|interpro:IPR033947	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Cw4dRHI2p2B3Ge4EJBFj2UT9b2Q9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H0YIN8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262854|ensembl:ENSP00000449781	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h0yin8_human(display_long)|uniprotkb:ANKRD13A(gene name)|psi-mi:ANKRD13A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000076513(gene)|ensembl:ENST00000547639(transcript)|go:"GO:0016020"(membrane)|interpro:IPR021832	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4MpnX/lh3esDOFKvYs3ow3Rs/jc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:H0YEA7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21266750|ensembl:ENSP00000435349	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:h0yea7_human(display_long)|uniprotkb:GNPTG(gene name)|psi-mi:GNPTG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	interpro:IPR044865|ensembl:ENSG00000090581(gene)|ensembl:ENST00000529110(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR039792|interpro:IPR039794	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:e5EdB3efDF1r/6gCvsCrsFAehjg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:Q9NVI7-3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-25339540|ensembl:ENSP00000439290	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:q9nvi7-3(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000197785(gene)|ensembl:ENST00000536055(transcript)|intact:EBI-352007(isoform-parent)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:fJvDRPIoHc84N+Kxf2shkOo1qB09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:G5E9T8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21261813|ensembl:ENSP00000414956	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:g5e9t8_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym)|uniprotkb:Golgi SNAP receptor complex member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0016021"(integral component of membrane)|interpro:IPR023601|ensembl:ENSG00000108587(gene)|ensembl:ENST00000414833(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:QcuR4o3fGy+b967k1bDPqk5h5809606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:F8VUA7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:F5H018	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262838|ensembl:ENSP00000444042	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:f5h018_human(display_long)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000132341(gene)|ensembl:ENST00000535090(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0015031"(protein transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0005525"(GTP binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:RkI4tk8Aq2MGDfs4/HIiHgWcOPY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:E9PHT6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258434|ensembl:ENSP00000421433|ensembl:ENSP00000486414|uniprotkb:A0A0G2JR38	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:e9pht6_human(display_long)|uniprotkb:PANK4(gene name)|psi-mi:PANK4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000157881(gene)|ensembl:ENSG00000273494(gene)|ensembl:ENST00000435556(transcript)|ensembl:ENST00000630982(transcript)|go:"GO:0004594"(pantothenate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002791(Protein of unknown function DUF89)|interpro:IPR004567(Eukaryotic pantothenate kinase)|interpro:IPR015844(Pantothenate kinase, acetyl-CoA regulated, two-domain type)|interpro:IPR035073|interpro:IPR036075|interpro:IPR043129	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:+/kJ1VQEJL3GZ5vmhaEGIsV3cO49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:E9PF19	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10969956|ensembl:ENSP00000413979	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:e9pf19_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000106638(gene)|ensembl:ENST00000432538(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ojeQr2CRmM8DQKuwoj39v7u8bZY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:E9PBL8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-10979568|ensembl:ENSP00000400111	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:e9pbl8_human(display_long)|uniprotkb:COG1(gene name)|psi-mi:COG1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000166685(gene)|ensembl:ENST00000438720(transcript)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|interpro:IPR033370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:/5Fg3wpubnf7vEHOAY8IemiNnBE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:E7ETY7	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262824|ensembl:ENSP00000427466	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:e7ety7_human(display_long)|uniprotkb:GPX8(gene name)|psi-mi:GPX8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000164294(gene)|ensembl:ENST00000515370(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0006979"(response to oxidative stress)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013376(Glutathione peroxidase Gpx7, putative)|interpro:IPR029760|interpro:IPR036249|refseq:NP_001293126.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ZVretoM7bZZ1SgAiDo2zCtorQZc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:E1NZA1	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258417	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:e1nza1_human(display_long)|uniprotkb:PRIC295(gene name)|psi-mi:PRIC295(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|interpro:IPR021133|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR034085	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Mc7wIreKhA0ofKgOHfyNzhQWdf09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:D6RIU4	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21266740|ensembl:ENSP00000427377	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:d6riu4_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000169223(gene)|ensembl:ENST00000513877(transcript)|go:"GO:0016020"(membrane)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:ujH+pk/DX0l/Q0WbBMfD6c/kRJc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9JW96	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258889|ensembl:ENSP00000393320	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9jw96_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000167085(gene)|ensembl:ENST00000419140(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:m+QS9IeeD5UlWLw8/X1LBNGUqMQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9JU30	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262814|ensembl:ENSP00000419516	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9ju30_human(display_long)|uniprotkb:ST7(gene name)|psi-mi:ST7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENST00000490039(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007311(ST7)|ensembl:ENSG00000004866(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Rm7BdWrtmoIXb94+d4CFmnlv43w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9JU26	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9JI87	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258875|ensembl:ENSP00000390129	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9ji87_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000213585(gene)|ensembl:ENST00000425992(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:XQBT9gfVRbapMMX65dSqFGkk7p09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9J4M6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:C9J2P2	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21262793|ensembl:ENSP00000410643	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:c9j2p2_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000105993(gene)|ensembl:ENST00000441561(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:PI3kVGcOb+bwk/QBRF7sQDXJvow9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:B7ZM73	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21260321	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:b7zm73_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0015031"(protein transport)|refseq:NP_001265400.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR026829|interpro:IPR032817|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR032691	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:NYoNvpNyCINMj8xmq0R6P+Mf6AE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:B7ZAQ6	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-11288340|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:B4DLT3|uniprotkb:B4DXE7|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302|ensembl:ENSP00000319673	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:gphra_human(display_long)|uniprotkb:GPR89A(gene name)|psi-mi:GPR89A(display_short)|uniprotkb:GPHRA(gene name synonym)|uniprotkb:GPR89(gene name synonym)|uniprotkb:Protein GPR89A(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM01(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 90(gene name synonym)|uniprotkb:SH120(gene name synonym)|uniprotkb:CGI-13(orf name)|uniprotkb:UNQ192/PRO218(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:NP_001091081.1|refseq:NP_001091082.2|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_005277459.1|refseq:XP_005277461.1|refseq:XP_006711440.1|refseq:XP_006711441.1|refseq:XP_006711555.1|refseq:XP_006711556.1|refseq:XP_011507912.1|refseq:XP_011507914.1|refseq:XP_011508210.1|refseq:XP_011508211.1|refseq:XP_016856937.1|ensembl:ENSG00000117262(gene)|ensembl:ENST00000313835(transcript)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051452"(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:B2RWN5	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21258368	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:A0FGR8	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H1C4	uniprotkb:A0A087WXG3	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-21266724|ensembl:ENSP00000480998	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:a0a087wxg3_human(display_long)|uniprotkb:BHLHE23(gene name)|psi-mi:BHLHE23(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21266770|imex:IM-26691-119	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSG00000125533(gene)|ensembl:ENST00000612929(transcript)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046671"(negative regulation of retinal cell programmed cell death)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048050"(post-embryonic eye morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032662|interpro:IPR036638|refseq:NP_542173.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/12/01	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:TU2F5SgOvZ29xaFks/nTLzpZs8Y9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9UQ80	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q96DI7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-538492|uniprotkb:O75938|uniprotkb:O95320|uniprotkb:B4DQJ1|ensembl:ENSP00000263694	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snr40_human(display_long)|uniprotkb:Prp8-binding protein(gene name synonym)|uniprotkb:U5 snRNP-specific 40 kDa protein(gene name synonym)|uniprotkb:38 kDa-splicing factor(gene name synonym)|uniprotkb:SNRNP40(gene name)|psi-mi:SNRNP40(display_short)|uniprotkb:PRP8BP(gene name synonym)|uniprotkb:SFP38(gene name synonym)|uniprotkb:WDR57(gene name synonym)|uniprotkb:WD repeat-containing protein 57(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004805.2|ensembl:ENSG00000060688(gene)|ensembl:ENST00000263694(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q96DI7|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:AfLoHYSy0MlW+OqHyEULLcpwQhQ9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P35251	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P35250	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O43264	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:A2RRP1	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_056993.2|dip:DIP-56726N|ensembl:ENSG00000151779(gene)|ensembl:ENST00000281513(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR029145|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9UNK0	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9UEU0	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-723716|ensembl:ENSP00000450731|uniprotkb:O43547|uniprotkb:Q96J28	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:vti1b_human(display_long)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 1(gene name synonym)|uniprotkb:Vti1-rp1(gene name synonym)|uniprotkb:VTI1B(gene name)|psi-mi:VTI1B(display_short)|uniprotkb:VTI1(gene name synonym)|uniprotkb:VTI1L(gene name synonym)|uniprotkb:VTI1L1(gene name synonym)|uniprotkb:VTI2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_006361.1|ensembl:ENSG00000100568(gene)|ensembl:ENST00000554659(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR038407|rcsb pdb:2V8S|reactome:R-HSA-114608|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:jJgdeKpTRzoaVS5zj+cPGKj05OM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9P0L0	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9NZ43	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-742842|uniprotkb:Q8NCK1|uniprotkb:Q9BRT4|ensembl:ENSP00000263897	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:use1_human(display_long)|uniprotkb:USE1L(gene name synonym)|uniprotkb:USE1-like protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM26(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:USE1(gene name)|psi-mi:USE1(display_short)|uniprotkb:MDS032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_060937.1|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015031"(protein transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031201"(SNARE complex)|go:"GO:0032940"(secretion by cell)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR019150|reactome:R-HSA-6811434|ensembl:ENSG00000053501(gene)|ensembl:ENST00000263897(transcript)|go:"GO:0005484"(SNAP receptor activity)|refseq:XP_016882464.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:Q1yMpc/L7/G3M+SehF5ix99OkVM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9NYM9	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-3924542|uniprotkb:B3KMY0|ensembl:ENSP00000372210	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:bet1l_human(display_long)|uniprotkb:BET1L(gene name)|psi-mi:BET1L(display_short)|uniprotkb:GS15(gene name synonym)|uniprotkb:Golgi SNARE with a size of 15 kDa(gene name synonym)|uniprotkb:Vesicle transport protein GOS15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001092257.1|ensembl:ENSG00000177951(gene)|ensembl:ENST00000382762(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|reactome:R-HSA-6807878|reactome:R-HSA-6811438|go:"GO:0031201"(SNARE complex)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:y5Ckvg6zKZghOu2wYZAwjymtibw9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9NV31	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-747481|uniprotkb:Q53G10|uniprotkb:B3KQ67|ensembl:ENSP00000326981|ensembl:ENSP00000385217	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:imp3_human(display_long)|uniprotkb:BRMS2(gene name synonym)|uniprotkb:IMP3(gene name)|psi-mi:IMP3(display_short)|uniprotkb:C15orf12(gene name synonym)|uniprotkb:MRPS4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_060755.1|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR022801|interpro:IPR036986|mint:Q9NV31|rcsb pdb:2CQJ|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0030515"(snoRNA binding)|ensembl:ENSG00000177971(gene)|ensembl:ENST00000314852(transcript)|ensembl:ENST00000403490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:7tf5HEal59lCqBIvQaFLksqchAw9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9NRW7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1782543|uniprotkb:Q15715|uniprotkb:Q9Y4Z6|uniprotkb:Q5T4P6|uniprotkb:F5H8K1|uniprotkb:Q53FR8|uniprotkb:D3DUZ9|ensembl:ENSP00000495563	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:vps45_human(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:VPS45A(gene name synonym)|uniprotkb:VPS45B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	dip:DIP-46823N|refseq:NP_009190.2|refseq:NP_001266282.1|refseq:NP_001266283.1|ensembl:ENSG00000136631(gene)|ensembl:ENST00000644510(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-HSA-6811438|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:EO8eXkh8EW/0AN2p5OqHL4yvXV09606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9H4G4	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-8787509|uniprotkb:Q5VZR1|uniprotkb:Q8N2S6|uniprotkb:Q8WWC9|uniprotkb:Q8WX36|ensembl:ENSP00000367196	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:gapr1_human(display_long)|uniprotkb:GLIPR2(gene name)|psi-mi:GLIPR2(display_short)|uniprotkb:C9orf19(gene name synonym)|uniprotkb:GAPR1(gene name synonym)|uniprotkb:Glioma pathogenesis-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_071738.1|go:"GO:0005615"(extracellular space)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR034113|interpro:IPR035940|rcsb pdb:1SMB|rcsb pdb:4AIW|rcsb pdb:5VHG|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000122694(gene)|ensembl:ENST00000377960(transcript)|dip:DIP-60127N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:u0wwfyS3oPa1OMxmusk2FGtcnGk9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9H3R2	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1171289|uniprotkb:Q6UWD9|uniprotkb:Q9NXT5|ensembl:ENSP00000485028	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:muc13_human(display_long)|uniprotkb:Down-regulated in colon cancer 1(gene name synonym)|uniprotkb:MUC13(gene name)|psi-mi:MUC13(display_short)|uniprotkb:DRCC1(gene name synonym)|uniprotkb:RECC(gene name synonym)|uniprotkb:UNQ6194/PRO20221(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_149038.3|ensembl:ENSG00000173702(gene)|ensembl:ENST00000616727(transcript)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000082(SEA)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR009030(Growth factor, receptor)|reactome:R-HSA-5083625|reactome:R-HSA-5083632|reactome:R-HSA-5083636|reactome:R-HSA-5621480|reactome:R-HSA-913709|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-977068	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:RJv84vtCAoM6LGCMZ6rsxoqCeyI9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9GZT3	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q9C0F1	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q99747	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-3221833|uniprotkb:B4DFC9|ensembl:ENSP00000324628|uniprotkb:Q9BUV1	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snag_human(display_long)|uniprotkb:NAPG(gene name)|psi-mi:NAPG(display_short)|uniprotkb:SNAPG(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000134265(gene)|ensembl:ENST00000322897(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0045202"(synapse)|go:"GO:0050821"(protein stabilization)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q99747|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:XP_011524058.1|refseq:NP_003817.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:QbHDxqDWn6/UYiMIOMiKfx5eCFg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q96JJ7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q96II8	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q96AJ9	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-3923262|uniprotkb:B4E137|uniprotkb:A2A307|ensembl:ENSP00000376792|uniprotkb:Q5W0D7	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:vti1a_human(display_long)|uniprotkb:VTI1A(gene name)|psi-mi:VTI1A(display_short)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 2(gene name synonym)|uniprotkb:Vti1-rp2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_660207.2|ensembl:ENSG00000151532(gene)|ensembl:ENST00000393077(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|mint:Q96AJ9|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001305132.1|refseq:NP_001305134.1|refseq:XP_005269601.1|dip:DIP-44223N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:MZOfyoq6Oe9cFxPKa3ZxWTuPTrI9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q8WYH8	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:dwJLwzNcL9866noaSFznDKeulRU9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q8WVM8	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q8TEH3	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-8796791|intact:EBI-28967334|ensembl:ENSP00000362727|uniprotkb:Q05C88|uniprotkb:D3PFD3|uniprotkb:Q8IVD6|uniprotkb:Q9H796|uniprotkb:B1AM80|uniprotkb:Q6PJZ5|uniprotkb:Q5VWF0|uniprotkb:B7Z669|uniprotkb:A8MZA3|uniprotkb:B7Z3C8	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:den1a_human(display_long)|uniprotkb:Connecdenn 1(gene name synonym)|uniprotkb:FAM31A(gene name synonym)|uniprotkb:KIAA1608(gene name synonym)|uniprotkb:Protein FAM31A(gene name synonym)|uniprotkb:DENND1A(gene name)|psi-mi:DENND1A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENST00000373618|ensembl:ENSP00000362720|ensembl:ENST00000373620|ensembl:ENSP00000362722|ensembl:ENSP00000362727|go:"GO:0030425"(dendrite)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|go:"GO:0030136"(clathrin-coated vesicle)|interpro:IPR037516|interpro:IPR043153|rcsb pdb:6EKK|reactome:R-HSA-8876198|interpro:IPR040032|ensembl:ENSG00000119522(gene)|ensembl:ENST00000373624(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|refseq:NP_065997.1|refseq:NP_079096.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:FAi3e2/uMk7/cXHabR2lzbEINUo9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q8NC51	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q8N3V7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-352936|intact:EBI-28982054|ensembl:ENSP00000377789|ensembl:ENSP00000428378|uniprotkb:O15271|uniprotkb:Q9UPX1|uniprotkb:A5PKZ8|uniprotkb:D3DQG8	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:synpo_human(display_long)|uniprotkb:SYNPO(gene name)|psi-mi:SYNPO(display_short)|uniprotkb:KIAA1029(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000171992(gene)|ensembl:ENST00000394243(transcript)|ensembl:ENST00000522122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0097444"(spine apparatus)|go:"GO:1905355"(spine apparatus assembly)|interpro:IPR028753|mint:Q8N3V7|go:"GO:0098886"(modification of dendritic spine)|refseq:NP_001103444.1|refseq:NP_001159680.1|refseq:NP_001159681.1|refseq:NP_009217.3|ensembl:ENST00000307662|ensembl:ENSP00000302139|ensembl:ENSP00000377789|ensembl:ENST00000519664|ensembl:ENSP00000429268|ensembl:ENSP00000428378|refseq:XP_011535854.1|refseq:XP_005268427.1|refseq:XP_005268428.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:rCCRVthnF+JTqcwh9lD+GFoWIpo9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q86UP2	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q7Z478	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-719925|uniprotkb:O75549|uniprotkb:Q63HN0|uniprotkb:Q63HN3|uniprotkb:Q8IWW2|uniprotkb:Q8N3A1|uniprotkb:Q9UMH2|intact:EBI-28967230|ensembl:ENSP00000251636	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:dhx29_human(display_long)|uniprotkb:DEAH box protein 29(gene name synonym)|uniprotkb:Nucleic acid helicase DDXx(gene name synonym)|uniprotkb:DHX29(gene name)|psi-mi:DHX29(display_short)|uniprotkb:DDX29(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSP00000251636|refseq:NP_061903.2|ensembl:ENSG00000067248(gene)|ensembl:ENST00000251636(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR034730|refseq:NP_001332893.1|refseq:NP_001332894.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:T78lwkAmdyEefThCR1zDrVbTBYE9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q6NZI2	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2559016|uniprotkb:O00535|uniprotkb:Q96H74|uniprotkb:Q6GMY1|uniprotkb:B2RAW7|uniprotkb:Q9BT85|uniprotkb:Q9HAP4|ensembl:ENSP00000349541	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:cavn1_human(display_long)|uniprotkb:CAVIN1(gene name)|psi-mi:CAVIN1(display_short)|uniprotkb:Cavin-1(gene name synonym)|uniprotkb:PTRF(gene name synonym)|uniprotkb:Polymerase I and transcript release factor(gene name synonym)|uniprotkb:FKSG13(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_036364.2|ensembl:ENSG00000177469(gene)|ensembl:ENST00000357037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009306"(protein secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR026752|mint:Q6NZI2|reactome:R-HSA-73863|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|interpro:IPR033297|dip:DIP-48550N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:55dzpwSSfj8aEzmgHKYdrHfgYBg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q6NUQ1	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q5SQN1	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-10244848|uniprotkb:Q8TB31|uniprotkb:Q9BT10|uniprotkb:Q5TBZ3|uniprotkb:Q96FE1|uniprotkb:Q8N558|uniprotkb:Q8WV46|uniprotkb:Q96CQ3|uniprotkb:Q8TCW8|uniprotkb:Q96NU3|uniprotkb:Q5HYB5|uniprotkb:Q96I66|uniprotkb:Q9BVB2|uniprotkb:B6EDE0	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snp47_human(display_long)|uniprotkb:SNAP47(gene name)|psi-mi:SNAP47(display_short)|uniprotkb:C1orf142(gene name synonym)|uniprotkb:Epididymis luminal protein 170(gene name synonym)|uniprotkb:HEL170(gene name synonym)|uniprotkb:SVAP1(gene name synonym)|uniprotkb:Synaptosomal-associated 47 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000727(Target SNARE coiled-coil region)|refseq:NP_444280.2|refseq:NP_001310864.1|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098793"(presynapse)|refseq:XP_016855720.1|refseq:XP_016855721.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:hKGKMfU5GPf/qU+vuwByphqX3NA9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q5JWF2	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-4400880|uniprotkb:A2A2S3|uniprotkb:E1P5G3|uniprotkb:O75684|uniprotkb:O75685|uniprotkb:Q5JW67|uniprotkb:Q5JWF1|uniprotkb:Q9NY42|ensembl:ENSP00000360141	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:gnas1_human(display_long)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Extra large alphas protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001296812.1|refseq:NP_536350.2|refseq:XP_016883302.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371100(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0060348"(bone development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q5JWF2|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:UmsO2DSEM3LmGMPwxSdkmlrKMLc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q32Q12	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-11897132|ensembl:ENSP00000451932	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:q32q12_human(display_long)|uniprotkb:NME1-NME2(gene name)|psi-mi:NME1-NME2(display_short)|uniprotkb:hCG_2001850(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000011052(gene)|ensembl:ENST00000555572(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:F9Z+VsBFIAci0CnyPOHlWo7SinY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q15185	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|refseq:NP_006592.3|dip:DIP-279N|ensembl:ENSG00000110958(gene)|ensembl:ENST00000262033(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043588"(skin development)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q15185|rcsb pdb:1EJF|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|rcsb pdb:1LG0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q13277	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1394295|uniprotkb:O43750|uniprotkb:O43751|uniprotkb:Q15360|uniprotkb:B4DME0|ensembl:ENSP00000338562	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx3_human(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004168.1|refseq:NP_001171511.1|refseq:XP_005274252.1|refseq:XP_005274257.1|ensembl:ENSG00000166900(gene)|ensembl:ENST00000337979(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR031186|mint:Q13277|reactome:R-HSA-449836	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:M/ue1L+l8LnUJNpEWVZ/KWR5UjM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q13190	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q12846	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:Q08380	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P62888	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P60880	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17|ensembl:ENSP00000254976	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:NP_003072.2|refseq:NP_570824.1|ensembl:ENSG00000132639(gene)|ensembl:ENST00000254976(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:XP_016883511.1|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|dip:DIP-34554N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P56962	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2797775|uniprotkb:Q4VXC2|ensembl:ENSP00000259400|ensembl:ENSP00000433484|ensembl:ENSP00000435981	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx17_human(display_long)|uniprotkb:STX17(gene name)|psi-mi:STX17(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:XP_011517122.1|refseq:XP_011517123.1|dip:DIP-47297N|refseq:NP_060389.2|ensembl:ENSG00000136874(gene)|ensembl:ENST00000259400(transcript)|ensembl:ENST00000525640(transcript)|ensembl:ENST00000534052(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028676|mint:P56962|rcsb pdb:4WY4|rcsb pdb:7BV4|rcsb pdb:7BV6|reactome:R-HSA-204005	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:fakGqDYa9LwX59Q3+PRDIQy/OU49606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P55060	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P54920	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P53621	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P51570	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P49755	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P46459	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P42704	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P20290	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741(gene)|ensembl:ENST00000380591(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P09211	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:P02786	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O96019	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O95721	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-490676|ensembl:ENSP00000215730	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004773.1|ensembl:ENSG00000099940(gene)|ensembl:ENST00000215730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019905"(syntaxin binding)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061025"(membrane fusion)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|dip:DIP-56475N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O94905	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O75396	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O60499	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-11343362|uniprotkb:Q96AE8|uniprotkb:Q6IAP4|uniprotkb:A6NC41|ensembl:ENSP00000466298	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx10_human(display_long)|uniprotkb:STX10(gene name)|psi-mi:STX10(display_short)|uniprotkb:SYN10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001258540.1|refseq:NP_003756.1|ensembl:ENSG00000104915(gene)|ensembl:ENST00000587230(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|rcsb pdb:4DND|reactome:R-HSA-6811440|dip:DIP-60563N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:PV1m5+whDK+Af3FGLEts82P1EyM9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O43752	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2695795|uniprotkb:Q5VY08|uniprotkb:B2R652|uniprotkb:Q6FH83|intact:EBI-28977663|ensembl:ENSP00000258301|uniprotkb:B4DR17	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx6_human(display_long)|uniprotkb:STX6(gene name)|psi-mi:STX6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSP00000258301|ensembl:ENST00000542060|ensembl:ENSP00000440188|refseq:NP_005810.1|ensembl:ENSG00000135823(gene)|ensembl:ENST00000258301(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:O43752|rcsb pdb:2NPS|rcsb pdb:4J2C|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001273139.1|refseq:XP_016855496.1|dip:DIP-44224N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:g8/HcXvvEY2Pqv8NWy3V+T+jBTY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O15400	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O14980	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O14745	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O14662	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-2853548|uniprotkb:B7ZBN3|uniprotkb:O14663|uniprotkb:Q5W086|uniprotkb:A6NN69|uniprotkb:Q9H0Z0|uniprotkb:O60517|uniprotkb:Q9UIX5|uniprotkb:Q5W087|uniprotkb:Q5XKI6|uniprotkb:Q5W084|uniprotkb:B7ZBN1|uniprotkb:B7ZBN2|uniprotkb:O14661|uniprotkb:Q9H1T7|uniprotkb:Q9H1T8|uniprotkb:E1P607|uniprotkb:A6NK32|uniprotkb:A8MPP0|uniprotkb:Q6GMS8|uniprotkb:E1P5M0|ensembl:ENSP00000360183	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:stx16_human(display_long)|uniprotkb:STX16(gene name)|psi-mi:STX16(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001001433.1|refseq:NP_001128245.1|refseq:NP_001191797.1|refseq:NP_003754.2|refseq:NP_001128244.1|dip:DIP-57570N|ensembl:ENSG00000124222(gene)|ensembl:ENST00000371141(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:pJ1TuU8Jl4SqtRPMYNCV0ZO0pRY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O14653	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-4401517|uniprotkb:D3DXJ6|uniprotkb:D3DXJ5|uniprotkb:Q96DA5|uniprotkb:Q9BZZ4|uniprotkb:Q8N4B8|ensembl:ENSP00000492751	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:gosr2_human(display_long)|uniprotkb:GOSR2(gene name)|psi-mi:GOSR2(display_short)|uniprotkb:GS27(gene name synonym)|uniprotkb:27 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:Membrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_001012529.1|refseq:NP_004278.2|refseq:NP_473363.1|ensembl:ENSG00000108433(gene)|ensembl:ENST00000640051(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3EG9|reactome:R-HSA-204005|reactome:R-HSA-381038|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:RWoVhfrHKdtVMlLtb5NRU/R2wRY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:O00161	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:G5E9T8	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21261813|ensembl:ENSP00000414956	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:g5e9t8_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym)|uniprotkb:Golgi SNAP receptor complex member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	go:"GO:0016021"(integral component of membrane)|interpro:IPR023601|ensembl:ENSG00000108587(gene)|ensembl:ENST00000414833(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:QcuR4o3fGy+b967k1bDPqk5h5809606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:F8VUA7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:E7ETY7	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21262824|ensembl:ENSP00000427466	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:e7ety7_human(display_long)|uniprotkb:GPX8(gene name)|psi-mi:GPX8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000164294(gene)|ensembl:ENST00000515370(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0006979"(response to oxidative stress)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013376(Glutathione peroxidase Gpx7, putative)|interpro:IPR029760|interpro:IPR036249|refseq:NP_001293126.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:ZVretoM7bZZ1SgAiDo2zCtorQZc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:B1AJQ6	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21260301|ensembl:ENSP00000392577	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:b1ajq6_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000117758(gene)|ensembl:ENST00000440806(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:0zq5qvXzoqXybBzDo4meAom6Psc9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:B0QY01	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21260971|ensembl:ENSP00000393714	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:b0qy01_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000100284(gene)|ensembl:ENST00000456128(transcript)|go:"GO:0015031"(protein transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:jdtzmZffSWVRwOcqA9DBmfKdUHI9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:A8MXH2	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-21262770|ensembl:ENSP00000382523|ensembl:ENSP00000487901	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:a8mxh2_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000399614(transcript)|ensembl:ENST00000634217(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:oqZISVLJYMBgTjnNm0Lolfl6lOs9606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O95183	uniprotkb:A0FGR8	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267749|imex:IM-26691-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2021/11/30	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:meRIXCbLuz6zM1HOt5xlD2Bk2h8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q6ZU35	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-11319666|uniprotkb:Q9NTE2|uniprotkb:Q9ULK9|uniprotkb:Q9NTP8|ensembl:ENSP00000264229|ensembl:ENSP00000423366|ensembl:ENSP00000507165	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cracd_human(display_long)|uniprotkb:CRACD(gene name)|psi-mi:CRACD(display_short)|uniprotkb:CRAD(gene name synonym)|uniprotkb:Cancer-related regulator of actin dynamics(gene name synonym)|uniprotkb:KIAA1211(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_065773.1|refseq:XP_005265809.1|refseq:XP_011532699.1|ensembl:ENSG00000109265(gene)|ensembl:ENST00000264229(transcript)|ensembl:ENST00000504228(transcript)|ensembl:ENST00000682029(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR028030	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:L/12y6fRwlL887BYRkdEjhnDRFw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q6P4F7	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-7543265|ensembl:ENSP00000355090|ensembl:ENSP00000479117|uniprotkb:B4DZN9|uniprotkb:Q9Y3S6|uniprotkb:Q6PI96|intact:MINT-3974818	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:rhgba_human(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000275568(gene)|ensembl:ENSG00000198826(gene)|refseq:NP_001273408.1|refseq:NP_001273409.1|ensembl:ENST00000361627(transcript)|ensembl:ENST00000619401(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|mint:Q6P4F7|rcsb pdb:3EAP|reactome:R-HSA-8980692|refseq:NP_955389.1|refseq:NP_055598.1|ensembl:ENSP00000355090|ensembl:ENST00000543522|ensembl:ENSP00000440073|ensembl:ENST00000565905|ensembl:ENST00000567348|ensembl:ENSP00000454575|ensembl:ENST00000611363|ensembl:ENSP00000480085|ensembl:ENSP00000479117|ensembl:ENST00000622253|ensembl:ENSP00000481011|ensembl:ENSP00000455754	-	-	comment:mint	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O75431	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|ensembl:ENSP00000249442|uniprotkb:Q8IZ68	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_001006636.1|refseq:NP_006545.1|ensembl:ENSG00000128654(gene)|ensembl:ENST00000249442(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)	-	-	comment:mint|function:Involved in transport of proteins into the mitochondrion	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:V9HW25	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21267978	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:v9hw25_human(display_long)|uniprotkb:HEL-S-273(gene name)|psi-mi:HEL-S-273(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|refseq:NP_001288155.1|refseq:NP_001288156.1|refseq:NP_998839.1|interpro:IPR000533(Tropomyosin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:ILBvAOMaHmB2ouyvYsNz3u10ucY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9Y608	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9Y512	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-748409|uniprotkb:Q969Y9|uniprotkb:Q96I46|uniprotkb:Q9NW85|uniprotkb:Q9UQM9|ensembl:ENSP00000345445|uniprotkb:Q53HC4|uniprotkb:Q56VW7	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:sam50_human(display_long)|uniprotkb:SAMM50(gene name)|psi-mi:SAMM50(display_short)|uniprotkb:CGI-51(orf name)|uniprotkb:Transformation-related gene 3 protein(gene name synonym)|uniprotkb:TRG3(orf name)|uniprotkb:SAM50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000100347(gene)|refseq:NP_056195.3|ensembl:ENST00000350028(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q9Y512|rcsb pdb:6YOO|rcsb pdb:6YOP|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:wpqEL4ia/LUNdXSlQBRZxPfwCcY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9P0L0	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9NP72	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9H2D6	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-715619|uniprotkb:B1AHD4|uniprotkb:B1AHD7|uniprotkb:O94797|uniprotkb:Q2PZW8|uniprotkb:Q2Q3Z9|uniprotkb:Q2Q400|uniprotkb:Q5R3M6|uniprotkb:Q96DW1|uniprotkb:Q9BT77|uniprotkb:Q9BTL7|uniprotkb:Q9BY98|uniprotkb:Q9Y3L4|ensembl:ENSP00000496394|intact:EBI-2560917|uniprotkb:F2Z2W0|uniprotkb:F8W6V6	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:tara_human(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym)|uniprotkb:HRIHFB2122(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001034230.1|refseq:NP_008963.3|refseq:NP_619538.2|ensembl:ENSG00000100106(gene)|ensembl:ENST00000644935(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030047"(actin modification)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045159"(myosin II binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051301"(cell division)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q9H2D6|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:2evioSQxAnH1x5VPGsZyK+fJTY09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9BY89	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-8796741|intact:EBI-28980779|ensembl:ENSP00000351207|ensembl:ENSP00000385152|uniprotkb:B7ZW08|uniprotkb:Q5THZ5|uniprotkb:B0QYF2	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:k1671_human(display_long)|uniprotkb:KIAA1671(gene name)|psi-mi:KIAA1671(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000197077(gene)|ensembl:ENST00000358431(transcript)|ensembl:ENST00000406486(transcript)|interpro:IPR032764|interpro:IPR040006|ensembl:ENSP00000351207|ensembl:ENST00000401395|ensembl:ENSP00000385377|ensembl:ENSP00000385152|refseq:XP_005261850.1|refseq:XP_005261851.1|refseq:NP_001138678.1|refseq:XP_006724409.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:7mCSVXo/8Z2MUHqsxKKXrBvOe749606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9BV38	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q9BR76	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q92828	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2835660|uniprotkb:Q92829|uniprotkb:Q5TBR5|uniprotkb:Q9BWS5|ensembl:ENSP00000343746|ensembl:ENSP00000364218	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cor2a_human(display_long)|uniprotkb:CORO2A(gene name)|psi-mi:CORO2A(display_short)|uniprotkb:IR10(gene name synonym)|uniprotkb:WDR2(gene name synonym)|uniprotkb:WD repeat-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:XP_011517288.1|refseq:NP_003380.3|refseq:NP_438171.1|ensembl:ENSG00000106789(gene)|ensembl:ENST00000343933(transcript)|ensembl:ENST00000375077(transcript)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051015"(actin filament binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027335|interpro:IPR036322|mint:Q92828|dip:DIP-59202N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:SOiS8h0Kv33gF44syiD028dKduM9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q8WUM4	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q8N5W9	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-716108|ensembl:ENSP00000331915	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:rflb_human(display_long)|uniprotkb:RFLNB(gene name)|psi-mi:RFLNB(display_short)|uniprotkb:Regulator of filamin protein B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_874364.1|ensembl:ENSG00000183688(gene)|ensembl:ENST00000329099(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0005737"(cytoplasm)|go:"GO:0031005"(filamin binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0061182"(negative regulation of chondrocyte development)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:1900158"(negative regulation of bone mineralization involved in bone maturation)|interpro:IPR028215	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:DpCSj+OZdhckdJxOOi2ZuCn6E9Y9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q8N5K1	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1045797|uniprotkb:Q7Z3D5|ensembl:ENSP00000273986	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cisd2_human(display_long)|uniprotkb:CDGSH2(gene name synonym)|uniprotkb:ERIS(gene name synonym)|uniprotkb:ZCD2(gene name synonym)|uniprotkb:Endoplasmic reticulum intermembrane small protein(gene name synonym)|uniprotkb:MitoNEET-related 1 protein(gene name synonym)|uniprotkb:CISD2(gene name)|psi-mi:CISD2(display_short)|uniprotkb:Nutrient-deprivation autophagy factor-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001008389.1|ensembl:ENSG00000145354(gene)|ensembl:ENST00000273986(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR018967|interpro:IPR019610|interpro:IPR042216|rcsb pdb:3FNV|rcsb pdb:4OO7|rcsb pdb:4OOA|go:"GO:0005741"(mitochondrial outer membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:YxickLtFNLILnuUDAXl1QqFadD09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q8N556	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-3893163|uniprotkb:A8K442|uniprotkb:Q59EY5|uniprotkb:Q9HBY1|uniprotkb:B4DMU2|uniprotkb:E9PDT7|ensembl:ENSP00000351245|ensembl:ENSP00000353402	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:afap1_human(display_long)|uniprotkb:AFAP1(gene name)|psi-mi:AFAP1(display_short)|uniprotkb:AFAP(gene name synonym)|uniprotkb:110 kDa actin filament-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:XP_011511846.1|refseq:NP_001128119.1|refseq:NP_940997.1|ensembl:ENSG00000196526(gene)|ensembl:ENST00000358461(transcript)|ensembl:ENST00000360265(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029907|interpro:IPR030113	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:RhPsp6U+J4FoLPSuXCw0KChvMOg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q7RTP6	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2555582|uniprotkb:E9PEF0|uniprotkb:Q5U4P4|uniprotkb:Q6ICK4|uniprotkb:Q9P2I3|intact:EBI-2558651|uniprotkb:O94909|uniprotkb:Q96DF2|ensembl:ENSP00000416015|uniprotkb:B2RXJ5	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:mica3_human(display_long)|uniprotkb:KIAA0819(gene name synonym)|uniprotkb:KIAA1364(gene name synonym)|uniprotkb:MICAL3(gene name)|psi-mi:MICAL3(display_short)|uniprotkb:Molecule interacting with CasL protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001116203.1|refseq:NP_056056.2|go:"GO:0007049"(cell cycle)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042995"(cell projection)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071949"(FAD binding)|go:"GO:0090543"(Flemming body)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR029941|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2D88|rcsb pdb:5SZG|rcsb pdb:6ICI|go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000243156(gene)|ensembl:ENST00000441493(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|refseq:NP_001129476.1|refseq:XP_005261319.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:Ve1WEQHry/REv1IzmmnyGGYd5No9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q7L7V1	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2807297|uniprotkb:Q9NV74|uniprotkb:Q96NY1|uniprotkb:Q9NVJ7|uniprotkb:Q9NSL5|uniprotkb:Q9H769|uniprotkb:Q5T3L5|uniprotkb:Q9BUN0|uniprotkb:Q5T3L0|uniprotkb:A8MSV2|uniprotkb:Q49AG5|uniprotkb:D3DRF9|ensembl:ENSP00000284690	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:dhx32_human(display_long)|uniprotkb:DHX32(gene name)|psi-mi:DHX32(display_short)|uniprotkb:DDX32(gene name synonym)|uniprotkb:DEAD/H box 32(gene name synonym)|uniprotkb:DEAD/H helicase-like protein 1(gene name synonym)|uniprotkb:DEAH box protein 32(gene name synonym)|uniprotkb:HuDDX32(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_060650.2|refseq:XP_016871893.1|refseq:XP_016871894.1|ensembl:ENSG00000089876(gene)|ensembl:ENST00000284690(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:IQFcD75pd5R0uajIotdMRpGXVeI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q6ZN40	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21267966|ensembl:ENSP00000350667	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:q6zn40_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:hCG_33495(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000140416(gene)|ensembl:ENST00000357980(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:XP_005254694.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:6C9PBRGY/pVsd5UlzI9PgQsRezw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q6YHK3	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2907947|uniprotkb:A5YKK4|uniprotkb:B2R948|uniprotkb:B3KW25|uniprotkb:Q0P6K7|uniprotkb:Q5SYA8|uniprotkb:Q5XUM7|uniprotkb:Q5XUM9|uniprotkb:Q6MZI7|uniprotkb:Q8N3A7|uniprotkb:Q8N915|uniprotkb:Q8TDJ2|uniprotkb:Q8TDJ3|ensembl:ENSP00000287097	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cd109_human(display_long)|uniprotkb:CD109(gene name)|psi-mi:CD109(display_short)|uniprotkb:CPAMD7(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7(gene name synonym)|uniprotkb:150 kDa TGF-beta-1-binding protein(gene name synonym)|uniprotkb:Platelet-specific Gov antigen(gene name synonym)|uniprotkb:p180(gene name synonym)|uniprotkb:r150(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001153059.1|refseq:NP_001153060.1|refseq:NP_598000.2|refseq:XP_005248716.1|ensembl:ENSG00000156535(gene)|ensembl:ENST00000287097(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0072675"(osteoclast fusion)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR041555|interpro:IPR041813|reactome:R-HSA-114608|reactome:R-HSA-163125	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:hQo7zh7QCDnuvY9RzCHEymkmlZg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q69YQ0	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351113|uniprotkb:O15081|intact:EBI-10965349|uniprotkb:B7Z758|uniprotkb:F5H1H6|ensembl:ENSP00000325785|ensembl:ENSP00000393363|ensembl:ENSP00000439633	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cytsa_human(display_long)|uniprotkb:SPECC1L(gene name)|psi-mi:SPECC1L(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-22(gene name synonym)|uniprotkb:CYTSA(gene name synonym)|uniprotkb:KIAA0376(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_056145.4|refseq:NP_001241661.2|dip:DIP-33173N|ensembl:ENSG00000100014(gene)|ensembl:ENST00000314328(transcript)|ensembl:ENST00000437398(transcript)|ensembl:ENST00000541492(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005921"(gap junction)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0051301"(cell division)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR040166|mint:Q69YQ0	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:iYg2RCRo/dMtmwyppU7ywkhkolI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:A0A0S2Z4G4	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21355809	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:a0a0s2z4g4_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_705935.1|interpro:IPR000533(Tropomyosin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:sDhDSAFlCFXE1fc07o1x9lrsubo9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q5M775	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-350473|uniprotkb:Q5IBP1|uniprotkb:Q5IBP2|uniprotkb:Q5IBP3|uniprotkb:Q5IBP4|uniprotkb:Q5M772|uniprotkb:Q5M773|uniprotkb:Q5M774|uniprotkb:Q86XT8|uniprotkb:Q8N4U4|uniprotkb:Q8WU84|uniprotkb:Q9HCQ3|uniprotkb:B4DHH0|ensembl:ENSP00000261503|ensembl:ENSP00000378898|ensembl:ENSP00000502924|ensembl:ENSP00000503971|ensembl:ENSP00000504211|uniprotkb:B7WNS8|intact:EBI-2556892	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cytsb_human(display_long)|uniprotkb:Nuclear structure protein 5(gene name synonym)|uniprotkb:Sperm antigen HCMOGT-1(gene name synonym)|uniprotkb:SPECC1(gene name)|psi-mi:SPECC1(display_short)|uniprotkb:CYTSB(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1(gene name synonym)|uniprotkb:NSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001028725.1|refseq:NP_001028726.1|refseq:NP_001028727.1|refseq:NP_001230367.1|refseq:NP_001230368.1|refseq:NP_690868.3|ensembl:ENSG00000128487(gene)|ensembl:ENST00000261503(transcript)|ensembl:ENST00000395527(transcript)|ensembl:ENST00000677914(transcript)|ensembl:ENST00000679058(transcript)|ensembl:ENST00000679255(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR036872|mint:Q5M775|interpro:IPR001715(Calponin-like actin-binding)|refseq:XP_016880814.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:iF+19RpfJDyn5whTFnPmDxxECz09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q562R1	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q32MZ4	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1369100|uniprotkb:O75766|uniprotkb:O75799|uniprotkb:Q32MZ5|uniprotkb:Q53T49|uniprotkb:Q6PKG2|uniprotkb:E9PGZ2|uniprotkb:Q9Y607|intact:EBI-28987401|ensembl:ENSP00000375857	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:lrrf1_human(display_long)|uniprotkb:LRRFIP1(gene name)|psi-mi:LRRFIP1(display_short)|uniprotkb:GCF2(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:TAR RNA-interacting protein(gene name synonym)|uniprotkb:GC-binding factor 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001131024.1|refseq:NP_001131025.1|refseq:NP_004726.2|ensembl:ENST00000244815|ensembl:ENSP00000244815|ensembl:ENST00000289175|ensembl:ENSP00000289175|ensembl:ENST00000308482|ensembl:ENSP00000310109|ensembl:ENSP00000375857|refseq:NP_001131022.1|ensembl:ENSG00000124831(gene)|ensembl:ENST00000392000(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR019139|mint:Q32MZ4|rcsb pdb:4H22|reactome:R-HSA-1839117|reactome:R-HSA-3134973|reactome:R-HSA-5655302	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:GRBGUu5k+BNhFDb4Z2B2XkQ0mcQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q16527	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q14684	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q14643	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-465548|ensembl:ENSP00000497605|uniprotkb:Q14660|uniprotkb:Q99897|uniprotkb:E7EPX7|uniprotkb:E9PDE9	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:itpr1_human(display_long)|uniprotkb:ITPR1(gene name)|psi-mi:ITPR1(display_short)|uniprotkb:INSP3R1(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000150995(gene)|ensembl:ENST00000649015(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-418457|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001093422.2|refseq:NP_002213.5|refseq:XP_011531985.1|dip:DIP-29714N|refseq:NP_001161744.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:54BRt783vU5D9fCHNO5uFJy1N7I9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q14247	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q13492	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|intact:EBI-28967113|ensembl:ENSP00000377015|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENST00000356360|ensembl:ENSP00000348718|ensembl:ENSP00000377015|ensembl:ENST00000526033|ensembl:ENSP00000433846|ensembl:ENST00000528398|ensembl:ENSP00000434884|ensembl:ENST00000532317|ensembl:ENSP00000436958|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030412|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0032050"(clathrin heavy chain binding)|ensembl:ENSG00000073921(gene)|ensembl:ENST00000393346(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097753"(membrane bending)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902959"(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:0055072"(iron ion homeostasis)|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q10589	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:vunnCOscGahFdaeN03pDo/8xW7I9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q05682	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q03001	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q02241	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q01082	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P80723	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P67936	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P62891	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P62736	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P62136	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P61421	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P61158	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P59998	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P54289	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-9690154|uniprotkb:Q17R45|uniprotkb:Q9UD80|uniprotkb:Q9UD81|uniprotkb:Q9UD82|ensembl:ENSP00000348589	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:ca2d1_human(display_long)|uniprotkb:CACNA2D1(gene name)|psi-mi:CACNA2D1(display_short)|uniprotkb:CACNL2A(gene name synonym)|uniprotkb:CCHL2A(gene name synonym)|uniprotkb:MHS3(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha-2/delta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_000713.2|refseq:XP_005250627.1|refseq:XP_005250629.1|refseq:XP_005250630.1|refseq:XP_005250631.1|ensembl:ENSG00000153956(gene)|ensembl:ENST00000356253(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0046872"(metal ion binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013608(VWA N-terminal)|interpro:IPR013680(Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region)|interpro:IPR036465	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:+IdPU9/mRR3gZjLuAHH7gXtgRlw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P52907	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P49458	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P47756	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P47755	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P46940	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P36873	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P35610	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-6621955|ensembl:ENSP00000356591|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:"Acyl-coenzyme A:cholesterol acyltransferase 1"(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0010878"(cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0034736"(cholesterol O-acyltransferase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|ensembl:ENSG00000057252(gene)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|ensembl:ENST00000367619(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004772"(sterol O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010742"(macrophage derived foam cell differentiation)|refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P31040	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P28290	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-722905|uniprotkb:Q8N7H2|uniprotkb:Q7Z7L2|uniprotkb:Q8N1L3|uniprotkb:Q8N263|uniprotkb:Q8NEN5|uniprotkb:Q96E36|uniprotkb:Q68DA6|uniprotkb:Q96PW1|uniprotkb:A8K6T0|intact:EBI-28986959|ensembl:ENSP00000388731	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:itpi2_human(display_long)|uniprotkb:ITPRID2(gene name)|psi-mi:ITPRID2(display_short)|uniprotkb:CS1(gene name synonym)|uniprotkb:Cleavage signal-1 protein(gene name synonym)|uniprotkb:ITPR-interacting domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1927(gene name synonym)|uniprotkb:KRAP(gene name synonym)|uniprotkb:Ki-ras-induced actin-interacting protein(gene name synonym)|uniprotkb:SSFA2(gene name synonym)|uniprotkb:Sperm-specific antigen 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001123917.1|refseq:NP_006742.2|refseq:NP_001274432.1|refseq:NP_001274433.1|ensembl:ENST00000320370|ensembl:ENSP00000314669|ensembl:ENSP00000388731|dip:DIP-47271N|ensembl:ENSG00000138434(gene)|ensembl:ENST00000431877(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR026648|interpro:IPR029325|interpro:IPR029326|interpro:IPR043444	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:oLYBDg++fr2C4VnIkkP5xhll5dw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P28289	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P21333	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P11172	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-723452|uniprotkb:O00758|uniprotkb:O00759|uniprotkb:O00760|uniprotkb:Q16862|uniprotkb:Q9H3Q2|uniprotkb:Q9UG49|ensembl:ENSP00000232607|uniprotkb:B5LY68|uniprotkb:B5LY72	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:umps_human(display_long)|uniprotkb:UMPS(gene name)|psi-mi:UMPS(display_short)|uniprotkb:OK/SW-cl.21(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_000364.1|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR018089|interpro:IPR023031|interpro:IPR029057|mint:P11172|rcsb pdb:2EAW|rcsb pdb:2JGY|rcsb pdb:2P1F|rcsb pdb:2QCC|rcsb pdb:2QCD|rcsb pdb:2QCE|rcsb pdb:2QCF|rcsb pdb:2QCG|rcsb pdb:2QCH|rcsb pdb:2QCL|go:"GO:0006222"(UMP biosynthetic process)|rcsb pdb:2QCM|rcsb pdb:2QCN|rcsb pdb:2V30|rcsb pdb:2WNS|rcsb pdb:3BGG|rcsb pdb:3BGJ|rcsb pdb:3BK0|go:"GO:0007565"(female pregnancy)|rcsb pdb:3BVJ|rcsb pdb:3DBP|go:"GO:0007595"(lactation)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|rcsb pdb:3EWU|rcsb pdb:3EWW|rcsb pdb:3EWY|rcsb pdb:3EWZ|rcsb pdb:3EX1|rcsb pdb:3EWX|rcsb pdb:3EX2|rcsb pdb:3EX3|rcsb pdb:3EX4|rcsb pdb:3EX6|rcsb pdb:3G3D|rcsb pdb:3G3M|rcsb pdb:3L0K|rcsb pdb:3L0N|rcsb pdb:3MI2|rcsb pdb:3MO7|rcsb pdb:3MW7|rcsb pdb:4HIB|rcsb pdb:4HKP|reactome:R-HSA-500753|ensembl:ENSG00000114491(gene)|ensembl:ENST00000232607(transcript)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|dip:DIP-29595N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:8HKx6eTv3pMPMJQzUhhFjyGXGZI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P09923	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P06396	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P05187	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1211484|uniprotkb:P05188|uniprotkb:P06861|uniprotkb:Q53S78|uniprotkb:Q96DB7|ensembl:ENSP00000375881	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:ppb1_human(display_long)|uniprotkb:ALPP(gene name)|psi-mi:ALPP(display_short)|uniprotkb:PLAP(gene name synonym)|uniprotkb:Placental alkaline phosphatase 1(gene name synonym)|uniprotkb:Alkaline phosphatase Regan isozyme(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001623.3|ensembl:ENSG00000163283(gene)|ensembl:ENST00000392027(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|mint:P05187|rcsb pdb:1EW2|rcsb pdb:1ZEB|rcsb pdb:1ZED|rcsb pdb:1ZEF|rcsb pdb:2GLQ|rcsb pdb:3MK0|rcsb pdb:3MK1|rcsb pdb:3MK2|reactome:R-HSA-6811438	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:JtfGSKMzJL3vP08X7lDS117PYbY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:P05186	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1054354|uniprotkb:A1A4E7|uniprotkb:O75090|uniprotkb:Q2TAI7|uniprotkb:Q59EJ7|uniprotkb:Q5BKZ5|uniprotkb:Q5VTG5|uniprotkb:Q6NZI8|uniprotkb:Q8WU32|uniprotkb:Q9UBK0|uniprotkb:B7Z387|uniprotkb:B2RMP8|uniprotkb:B7Z4Y6|ensembl:ENSP00000363965|ensembl:ENSP00000363973	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:ppbt_human(display_long)|uniprotkb:Alkaline phosphatase liver/bone/kidney isozyme(gene name synonym)|uniprotkb:ALPL(gene name)|psi-mi:ALPL(display_short)|uniprotkb:Phosphoamidase(gene name synonym)|uniprotkb:Phosphocreatine phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_000469.3|refseq:NP_001120973.2|refseq:NP_001170991.1|refseq:XP_005245875.1|refseq:XP_006710609.1|ensembl:ENSG00000162551(gene)|ensembl:ENST00000374832(transcript)|ensembl:ENST00000374840(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016462"(pyrophosphatase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033280"(response to vitamin D)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071529"(cementum mineralization)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-163125	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:iO0/TZ5yjqLOEZWp673XGt02mnI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O75369	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O75128	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-3446582|uniprotkb:A4D257|uniprotkb:B7ZLW9|uniprotkb:B9EGF8|uniprotkb:Q8TCM1|uniprotkb:Q8N304|uniprotkb:A7E2B0|uniprotkb:Q86XA7|uniprotkb:Q504Y4|uniprotkb:Q2T9J3|intact:EBI-28974386|ensembl:ENSP00000265136	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:cobl_human(display_long)|uniprotkb:COBL(gene name)|psi-mi:COBL(display_short)|uniprotkb:KIAA0633(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSP00000265136|ensembl:ENST00000395540|ensembl:ENSP00000378910|ensembl:ENST00000395542|ensembl:ENSP00000378912|ensembl:ENST00000441453|ensembl:ENSP00000399500|refseq:XP_011513537.1|refseq:NP_056013.2|refseq:NP_001274365.1|refseq:NP_001274367.1|refseq:NP_001333370.1|refseq:NP_001333371.1|refseq:NP_001333372.1|refseq:NP_001333373.1|ensembl:ENSG00000106078(gene)|ensembl:ENST00000265136(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001726"(ruffle)|go:"GO:0001757"(somite specification)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016020"(membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030903"(notochord development)|go:"GO:0033504"(floor plate development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048565"(digestive tract development)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0051639"(actin filament network formation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990357"(terminal web)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|mint:O75128|rcsb pdb:4PL8	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:mkEX2B5sVoK8CD6RWVVCp912otg9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O75083	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O60427	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1055473|uniprotkb:B2RAI0|uniprotkb:Q53GM5|uniprotkb:Q8N3A6|uniprotkb:Q8NCC7|uniprotkb:Q8NCG0|uniprotkb:Q96I39|uniprotkb:Q96SV3|uniprotkb:Q96T10|uniprotkb:Q9NRP8|uniprotkb:Q9NYX1|uniprotkb:A8K0I7	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:fads1_human(display_long)|uniprotkb:"Delta(5) fatty acid desaturase"(gene name synonym)|uniprotkb:FADS1(gene name)|psi-mi:FADS1(display_short)|uniprotkb:FADSD5(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_037534.3|interpro:IPR001199(Cytochrome b5)|interpro:IPR012171(Fatty acid/sphingolipid desaturase)|interpro:IPR005804(Fatty acid desaturase, type 1)|reactome:R-HSA-2046106|reactome:R-HSA-1989781|reactome:R-HSA-2046105|go:"GO:0000248"(C-5 sterol desaturase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016213"(linoleoyl-CoA desaturase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045485"(omega-6 fatty acid desaturase activity)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046456"(icosanoid biosynthetic process)|go:"GO:0062076"(acyl-CoA delta5-desaturase activity)|interpro:IPR036400	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:QbDub2xthvy52AHQlav+slJkEVM9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O43166	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-310678|uniprotkb:O95321|uniprotkb:Q9UDU4|uniprotkb:Q9UNU4|intact:EBI-11025469|intact:EBI-28973250|uniprotkb:J3KP19|ensembl:ENSP00000450832	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:si1l1_human(display_long)|uniprotkb:SIPA1L1(gene name)|psi-mi:SIPA1L1(display_short)|uniprotkb:E6TP1(gene name synonym)|uniprotkb:KIAA0440(gene name synonym)|uniprotkb:High-risk human papilloma viruses E6 oncoproteins targeted protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENST00000358550|ensembl:ENSP00000351352|ensembl:ENST00000381232|ensembl:ENSP00000370630|ensembl:ENSP00000450832|refseq:NP_001271174.1|refseq:NP_001271175.1|refseq:NP_056371.1|refseq:XP_005267573.1|refseq:XP_011534932.1|refseq:XP_011534933.1|refseq:XP_011534934.1|refseq:XP_011534937.1|refseq:XP_016876648.1|refseq:XP_016876649.1|refseq:XP_016876650.1|refseq:XP_016876651.1|refseq:XP_016876652.1|refseq:XP_016876653.1|refseq:XP_016876654.1|refseq:XP_016876655.1|refseq:XP_016876656.1|refseq:XP_016876657.1|refseq:XP_016876658.1|refseq:XP_016876659.1|refseq:XP_016876660.1|refseq:XP_016876661.1|refseq:XP_016876662.1|refseq:XP_016876663.1|refseq:XP_016876664.1|refseq:XP_016876665.1|refseq:XP_016876666.1|refseq:XP_016876667.1|refseq:XP_016876668.1|refseq:XP_016876669.1|refseq:XP_016876675.1|refseq:XP_016876676.1|refseq:XP_016876677.1|refseq:XP_016876678.1|refseq:XP_016876679.1|refseq:XP_016876680.1|refseq:XP_016876681.1|refseq:XP_016876682.1|ensembl:ENSG00000197555(gene)|ensembl:ENST00000555818(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR030770|interpro:IPR035974|interpro:IPR036034|mint:O43166|reactome:R-HSA-6794361	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:whpEjAhxfeYqeZ1IbjNl6romgXk9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15511	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15355	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15269	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15173	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15145	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-351829|uniprotkb:O00554|ensembl:ENSP00000228825	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arpc3_human(display_long)|uniprotkb:ARPC3(gene name)|psi-mi:ARPC3(display_short)|uniprotkb:ARC21(gene name synonym)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000111229(gene)|ensembl:ENST00000228825(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0061850"(growth cone leading edge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|mint:O15145|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001274151.1|refseq:NP_001265485.1|dip:DIP-33187N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:u4h1270mPo3E3GBrEurYtpUYTQM9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15144	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O15143	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:O00264	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:K7ENT6	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21257974|ensembl:ENSP00000467087	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:k7ent6_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000167460(gene)|ensembl:ENST00000586833(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:XP_011526533.1|refseq:XP_016882678.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:jIv0VHn6SEMHjGl4RfAAdcgdIN89606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:K7ELP0	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21264381|ensembl:ENSP00000466158	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:k7elp0_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000167460(gene)|ensembl:ENST00000589897(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:nf+uf96mgXvNBcYTa7wOUzPznr09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:I3L192	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21264369|ensembl:ENSP00000458665	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:i3l192_human(display_long)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000172270(gene)|ensembl:ENST00000573216(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:s2h7cByi0kSTLQepPGxFhBMisl09606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:F8VRD2	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21261005|ensembl:ENSP00000448697	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:f8vrd2_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000161800(gene)|ensembl:ENST00000552310(transcript)|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:+TaqRZpsPlIIziSlAIvmPtmyqCY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:F5H7S3	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21257963|ensembl:ENSP00000322577	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:f5h7s3_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000140416(gene)|ensembl:ENST00000317516(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR000533(Tropomyosin)|refseq:NP_001317280.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:Xck0zh7JpqM6KjZcOaUvFulRo4U9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:F5H6T1	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21264355|ensembl:ENSP00000437383	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:f5h6t1_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:hCG_21224(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENST00000542850(transcript)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|ensembl:ENSG00000138071(gene)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:uXvYJxPxUJei6wa98fJ5pGPYy/U9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:E7EUA0	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21260998|ensembl:ENSP00000411902	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:e7eua0_human(display_long)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000162614(gene)|ensembl:ENST00000440324(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|interpro:IPR043204	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:SlTPTP3OarDZU+8vTbyeo9nHhLU9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:C9JVY5	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21264337|ensembl:ENSP00000419268	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:c9jvy5_human(display_long)|uniprotkb:PALM2AKAP2(gene name)|psi-mi:PALM2AKAP2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000157654(gene)|ensembl:ENST00000480388(transcript)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:2feZz9Fntb5b9eMJVOgYVshLcFY9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:B7Z6G4	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21262067	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:b7z6g4_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0017022"(myosin binding)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:dCvW0uwS4D8+zjT93un5NOx5HTQ9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:B4E106	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21260312	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:b4e106_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR030757|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:uuGPwK8ZAO210iuWpBp+TK7fKNo9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:A8K3Y5	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-21264330	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:a8k3y5_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR039999|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR041010	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:sOsf6bNg+ln+0tCDWvRys6RZ0/w9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:Q15154	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96GC9	uniprotkb:A1L390	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	intact:EBI-4401429|ensembl:ENSP00000247226|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21267986|imex:IM-26691-133	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	ensembl:ENSG00000126822(gene)|ensembl:ENST00000247226(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|ensembl:ENSP00000247226|ensembl:ENST00000394691|ensembl:ENSP00000378183|refseq:XP_016876646.1|refseq:NP_001295076.1	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/11/15	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rogid:+obep09w4klmkB8i13aA5FQW2609606	rigid:h16X6QGtVxcT3TVDCFo9ag+i8Fk	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H171	uniprotkb:Q8NDX6	intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1	intact:EBI-2602428|uniprotkb:A8K9M9|ensembl:ENSP00000409463	psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym)	psi-mi:zn740_human(display_long)|uniprotkb:ZNF740(gene name)|psi-mi:ZNF740(display_short)|uniprotkb:TB7(gene name synonym)|uniprotkb:OriLyt TD-element-binding protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268261|imex:IM-26691-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N	refseq:NP_001004304.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000139651(gene)|ensembl:ENST00000416904(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606	rogid:2i7f+rUftAUiFntFARDjwFBLfrs9606	rigid:G+zkHFnQJmFsfk9WuFU3dai/RqM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H171	uniprotkb:P40926	intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1	intact:EBI-721232|uniprotkb:O43682|uniprotkb:B4DE44|uniprotkb:E9PDB2|uniprotkb:A8K414|uniprotkb:B2RE78|ensembl:ENSP00000327070	psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym)	psi-mi:mdhm_human(display_long)|uniprotkb:MDH2(gene name)|psi-mi:MDH2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268261|imex:IM-26691-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N	refseq:NP_005909.2|refseq:NP_001269332.1|refseq:NP_001269333.1|ensembl:ENSG00000146701(gene)|ensembl:ENST00000315758(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40926|rcsb pdb:2DFD|rcsb pdb:4WLE|rcsb pdb:4WLF|rcsb pdb:4WLN|rcsb pdb:4WLO|rcsb pdb:4WLU|rcsb pdb:4WLV|reactome:R-HSA-70263|reactome:R-HSA-71403	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606	rogid:Ur2aO+2M7e/ftD8RlhPMHBc8/JU9606	rigid:G+zkHFnQJmFsfk9WuFU3dai/RqM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H171	uniprotkb:P12694	intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1	intact:EBI-1029053|uniprotkb:Q16034|uniprotkb:Q16472|uniprotkb:B4DP47|uniprotkb:E7EW46|ensembl:ENSP00000269980	psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym)	psi-mi:odba_human(display_long)|uniprotkb:BCKDHA(gene name)|psi-mi:BCKDHA(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268261|imex:IM-26691-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N	refseq:NP_000700.1|ensembl:ENSG00000248098(gene)|ensembl:ENST00000269980(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR034616|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|refseq:NP_001158255.1|dip:DIP-6146N	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606	rogid:dfjLnS4YI8gwCQljkXL3W24I/DY9606	rigid:G+zkHFnQJmFsfk9WuFU3dai/RqM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H171	uniprotkb:O95478	intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1	intact:EBI-2852366|ensembl:ENSP00000483484	psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym)	psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268261|imex:IM-26691-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N	refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606	rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606	rigid:G+zkHFnQJmFsfk9WuFU3dai/RqM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H171	uniprotkb:H3BTL2	intact:EBI-6264672|ensembl:ENSP00000360215|uniprotkb:A2A2F7|uniprotkb:B3KVA1|uniprotkb:Q5JY39|uniprotkb:Q9BYW4|uniprotkb:F5GYT1	intact:EBI-21268250|ensembl:ENSP00000457226	psi-mi:zbp1_human(display_long)|uniprotkb:ZBP1(gene name)|psi-mi:ZBP1(display_short)|uniprotkb:C20orf183(gene name synonym)|uniprotkb:DLM1(gene name synonym)|uniprotkb:Tumor stroma and activated macrophage protein DLM-1(gene name synonym)|uniprotkb:DNA-dependent activator of IFN-regulatory factors(gene name synonym)	psi-mi:h3btl2_human(display_long)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268261|imex:IM-26691-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000124256(gene)|ensembl:ENST00000371173(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003692"(left-handed Z-DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:2000659"(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042361|interpro:IPR042371|mint:Q9H171|rcsb pdb:2L4M|rcsb pdb:2LNB|rcsb pdb:3EYI|rcsb pdb:4KA4|reactome:R-HSA-1606322|reactome:R-HSA-1606341|reactome:R-HSA-1810476|reactome:R-HSA-3134975|reactome:R-HSA-9679191|go:"GO:0050727"(regulation of inflammatory response)|refseq:NP_001310895.1|refseq:NP_001153889.1|refseq:NP_001153890.1|refseq:NP_110403.2|refseq:NP_001153891.1|dip:DIP-44121N	ensembl:ENSG00000103507(gene)|ensembl:ENST00000484226(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR018955|interpro:IPR036784|interpro:IPR039028	-	-	-	figure legend:Figures 1a and 5, Suppl. Table 2, Suppl. Figures 2e, 2f and 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/18	rogid:Tu0wt0TeuDYF8q++Zl97sy6weZQ9606	rogid:Z2/gFdzz3pEtf4TRYnxxfyrRZ7k9606	rigid:G+zkHFnQJmFsfk9WuFU3dai/RqM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q7Z6Z7	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P15659	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-8431752|intact:MINT-8081657	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:pa_i33a0(display_long)|uniprotkb:PA(gene name)|psi-mi:PA(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|mint:P15659|interpro:IPR038372|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:4IUJ|rcsb pdb:5IEQ|rcsb pdb:5IF2|rcsb pdb:5IF5|rcsb pdb:5IF7|rcsb pdb:5IF8|rcsb pdb:5IFB|rcsb pdb:5IFC|rcsb pdb:5IFD|rcsb pdb:5V0U|rcsb pdb:6CFP	-	comment:mint	comment:mint	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:Ql7usL6x8LoOsNX1cAXxXi5yWoE381518	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P03430	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-8434155|intact:MINT-8081772	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rdrp_i33a0(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)	-	comment:mint	comment:mint	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:+yiKMmFFKMH4T76KuEhjUa4RT9E381518	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:V9GY61	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268413|ensembl:ENSP00000476427	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:v9gy61_human(display_long)|uniprotkb:RAB34(gene name)|psi-mi:RAB34(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000109113(gene)|ensembl:ENST00000582934(transcript)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:Z7Ml3zdIKrjKTRZ2e6BYat8fDzQ9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9Y4B6	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9UNK9	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-12579907|ensembl:ENSP00000251089|uniprotkb:B4DWL7|uniprotkb:O94859|uniprotkb:Q8NCS9	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ange1_human(display_long)|uniprotkb:ANGEL1(gene name)|psi-mi:ANGEL1(display_short)|uniprotkb:KIAA0759(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000013523(gene)|ensembl:ENST00000251089(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|mint:Q9UNK9|refseq:NP_056120.2	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:5WcU0CTNKN6ZYR5zg4oa1LuuAlE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9ULX6	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9ULD2	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-2818124|uniprotkb:A8K135|uniprotkb:Q9H7T2|uniprotkb:Q6PK49|uniprotkb:Q659F4|uniprotkb:B3KWJ9|uniprotkb:B9EGA1|uniprotkb:Q63HJ6|uniprotkb:Q8WTT9|uniprotkb:Q8N4M6|uniprotkb:Q6URW7|uniprotkb:B2RBJ6|uniprotkb:D3DSP8|uniprotkb:B4DH03|ensembl:ENSP00000262102	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:mtus1_human(display_long)|uniprotkb:MTUS1(gene name)|psi-mi:MTUS1(display_short)|uniprotkb:ATBP(gene name synonym)|uniprotkb:ATIP(gene name synonym)|uniprotkb:GK1(gene name synonym)|uniprotkb:KIAA1288(gene name synonym)|uniprotkb:MTSG1(gene name synonym)|uniprotkb:AT2 receptor-binding protein(gene name synonym)|uniprotkb:Angiotensin-II type 2 receptor-interacting protein(gene name synonym)|uniprotkb:Mitochondrial tumor suppressor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001001924.1|refseq:NP_001001925.1|refseq:NP_001001931.1|refseq:NP_001159865.1|refseq:NP_065800.1|refseq:NP_001317399.1|refseq:XP_016869189.1|refseq:XP_016869190.1|refseq:XP_016869191.1|ensembl:ENSG00000129422(gene)|ensembl:ENST00000262102(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR029786|refseq:XP_005273636.1|refseq:XP_005273639.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:48081802hEyRtGe+P2jOMZG0QWs9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9UL15	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9H078	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9BW61	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-2510241|ensembl:ENSP00000352928|ensembl:ENSP00000472171|ensembl:ENSP00000473086	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:dda1_human(display_long)|uniprotkb:DDA1(gene name)|psi-mi:DDA1(display_short)|uniprotkb:C19orf58(gene name synonym)|uniprotkb:PCIA1(gene name synonym)|uniprotkb:Placenta cross-immune reaction antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000130311(gene)|ensembl:ENST00000359866(transcript)|ensembl:ENST00000593466(transcript)|ensembl:ENST00000596582(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR018276|interpro:IPR033575|mint:Q9BW61|rcsb pdb:6DSZ|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|reactome:R-HSA-8951664|refseq:NP_076955.1|dip:DIP-53527N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:yD3tRVKVhirdHUj58DCTphW7ZYs9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9BUL8	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q9BUF5	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q96K17	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-6137496|uniprotkb:D3DQ32|uniprotkb:B3KNJ1|uniprotkb:G3V1C6|ensembl:ENSP00000360664	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:bt3l4_human(display_long)|uniprotkb:BTF3L4(gene name)|psi-mi:BTF3L4(display_short)|uniprotkb:Basic transcription factor 3-like 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_689478.1|refseq:NP_001230696.1|refseq:NP_001129969.1|ensembl:ENSG00000134717(gene)|ensembl:ENST00000313334(transcript)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:UL7VE0uKz9mYvpFq8E2FLKrBmOA9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q96EY1	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q96D53	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q92688	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q92598	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q82506	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-6149498	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ns1_i33a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	dip:DIP-60861N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:MUZC+RgMkeOaNXYbbKi2RfXyVsw381518	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q6PI48	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-3917045|ensembl:ENSP00000497569	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:sydm_human(display_long)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:DARS2(gene name)|psi-mi:DARS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_060592.2|ensembl:ENSG00000117593(gene)|ensembl:ENST00000649689(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043039"(tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|go:"GO:0070145"(mitochondrial asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029351|rcsb pdb:4AH6|reactome:R-HSA-379726|go:"GO:0005759"(mitochondrial matrix)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:6tNhPqrlJ5dCXoDIgUjcUB/gA7s9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q68D27	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21261767	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:q68d27_human(display_long)|uniprotkb:DKFZp686B20267(gene name)|psi-mi:DKFZp686B20267(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|refseq:NP_001280202.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:THsbOklraRO84LO3t3QenHcGLRY9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q5H9R7	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q16531	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q14257	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q13347	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:fogC6nSNmIynV2ziHZboT9laA3M9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q13263	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:Q01105	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P82930	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P82650	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P54652	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P39687	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P34932	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P31689	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P27105	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-1211440|uniprotkb:Q14087|uniprotkb:Q15609|uniprotkb:Q5VX96|uniprotkb:Q96FK4|uniprotkb:B1AM77|ensembl:ENSP00000286713	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:stom_human(display_long)|uniprotkb:STOM(gene name)|psi-mi:STOM(display_short)|uniprotkb:BND7(gene name synonym)|uniprotkb:EPB72(gene name synonym)|uniprotkb:Protein 7.2b(gene name synonym)|uniprotkb:Erythrocyte band 7 integral membrane protein(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 7.2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_004090.4|refseq:NP_937837.1|ensembl:ENSG00000148175(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|ensembl:ENST00000286713(transcript)|go:"GO:0016020"(membrane)|go:"GO:0031982"(vesicle)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901585"(regulation of acid-sensing ion channel activity)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR018080|interpro:IPR028515|interpro:IPR036013|interpro:IPR043202|mint:P27105|reactome:R-HSA-2672351|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:vN/5Kc8T+vO90Hk4N3RHD/u0pWc9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P25398	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P19388	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P17066	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P15682	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268362	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ncap_i33a0(display_long)|uniprotkb:NP(gene name)|psi-mi:NP(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6J1U|rcsb pdb:3ZDP|rcsb pdb:4BBL|rcsb pdb:4IRY|rcsb pdb:5B7B|interpro:IPR002141("Influenza virus nucleoprotein (NP)")|rcsb pdb:6I7B|rcsb pdb:6I85	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:YwnvNB9Y/OH7YhHh/6xj6QhLvBk381518	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P11279	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	intact:EBI-11820565	intact:EBI-8430745|intact:MINT-8081619	-	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	-	-	comment:mint	comment:P0DMV8,P0DMV9	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	-	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P06730	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:P05455	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O95816	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O75718	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-2515576|ensembl:ENSP00000323696|uniprotkb:B2RBL6	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:crtap_human(display_long)|uniprotkb:CRTAP(gene name)|psi-mi:CRTAP(display_short)|uniprotkb:CASP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000170275(gene)|ensembl:ENST00000320954(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007283"(spermatogenesis)|go:"GO:0018400"(peptidyl-proline hydroxylation to 3-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033212|mint:O75718|reactome:R-HSA-1650814|refseq:NP_006362.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:7rtGL+UxGVyDTmnJagIzXaUziIw9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O75494	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O75340	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O60884	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O15355	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O00629	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:/cng/xZ42E2juzHNOpuQTP+amx89606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O00505	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O00267	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:8VodOhZyrmNy3xxDTTsB8KugN849606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:O00165	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:I3L318	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268354|ensembl:ENSP00000460101	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:i3l318_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000132361(gene)|ensembl:ENST00000576885(transcript)|interpro:IPR028275	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:LPzF3dTL8N7vwGkJP/1X7eNF5Jw9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:H3BS86	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21259582|ensembl:ENSP00000456591	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:h3bs86_human(display_long)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000103266(gene)|ensembl:ENST00000567173(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041312	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:kIb5YkvjJXhsREYdDvtNbuGPOdE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:H0YBB4	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268347|ensembl:ENSP00000429127	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:h0ybb4_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000104517(gene)|ensembl:ENST00000520898(transcript)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:KU1yA+zbr2ppw7I6OErSJLGMke09606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:F5H7A5	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268337|ensembl:ENSP00000442651	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:f5h7a5_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	interpro:IPR036770|interpro:IPR020683|ensembl:ENSG00000162129(gene)|ensembl:ENST00000544683(transcript)|interpro:IPR002110(Ankyrin)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:8OQrltj5cOhzvFBpR1vC4xTEcBA9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:F5H0Y3	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268329|ensembl:ENSP00000439789	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:f5h0y3_human(display_long)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000089693(gene)|ensembl:ENST00000537126(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR019376	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:m+St2tMZ7Ts/3cPvXZXg5XlmNgw9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:E9PMD8	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268316|ensembl:ENSP00000431144	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:e9pmd8_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000165916(gene)|ensembl:ENST00000530651(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0036402"(proteasome-activating activity)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:UT+8pOgFPtNVGLPH5L/m2tsWtBE9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:E9PK54	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21268306|ensembl:ENSP00000431641	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:e9pk54_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000109971(gene)|ensembl:ENST00000534567(transcript)|go:"GO:0005524"(ATP binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR043129	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:ztz+vk0yw09IH9nSz1A5YOiUCSg9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	intact:EBI-21268291	intact:EBI-8430745|intact:MINT-8081619	-	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:e7erx5_human(display_short)|psi-mi:EBI-21268291(display_long)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	uniprotkb:E7ERX5(uniprot-removed-ac)	-	comment:mint	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:AVBXotPLnXlgE3Fuwc/Y+YRg0ks9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:C9JLU1	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-11076042|ensembl:ENSP00000409065	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:c9jlu1_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000163882(gene)|ensembl:ENST00000455712(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:cWioC0bRrUHFlH3rBu2AwgRiKiY9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:C9J4M6	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21258392|ensembl:ENSP00000391096	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:c9j4m6_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|ensembl:ENSG00000047315(gene)|ensembl:ENST00000431623(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:GIELKPj0qAtHnKdsXXwUpvPryVs9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P03427	uniprotkb:C9J2P2	intact:EBI-8430745|intact:MINT-8081619	intact:EBI-21262793|ensembl:ENSP00000410643	psi-mi:pb2_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)	psi-mi:c9j2p2_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268420|imex:IM-26691-135	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)	ensembl:ENSG00000105993(gene)|ensembl:ENST00000441561(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869	-	comment:mint	-	figure legend:Figure 3a, Suppl. Figure 3f, Suppl. Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2019/01/08	2020/10/15	rogid:8pmp1vzps0rWGGF/TVeDB8MOlrQ381518	rogid:PI3kVGcOb+bwk/QBRF7sQDXJvow9606	-	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O15111	uniprotkb:Q99558	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21268621|imex:IM-26691-173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	-	-	-	figure legend:Suppl. Figure 6g, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rigid:3Dy0tdp7ZJfhIP/jYvzN7PrcDeo	false	-	tandem tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q969M3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2124787|uniprotkb:Q4VSN6|uniprotkb:Q53EX4|uniprotkb:Q8NHE5|uniprotkb:Q9H338|uniprotkb:Q9H3U4|uniprotkb:D3DQF5|ensembl:ENSP00000274496|ensembl:ENSP00000397704	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:yipf5_human(display_long)|uniprotkb:YIPF5(gene name)|psi-mi:YIPF5(display_short)|uniprotkb:FINGER5(gene name synonym)|uniprotkb:YIP1A(gene name synonym)|uniprotkb:YIP1 family member 5(gene name synonym)|uniprotkb:YPT-interacting protein 1 A(gene name synonym)|uniprotkb:Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 5(gene name synonym)|uniprotkb:PP12723(orf name)|uniprotkb:SB140(orf name)|uniprotkb:UNQ3123/PRO10275(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001020118.1|refseq:NP_110426.4|refseq:NP_001258661.1|ensembl:ENST00000274496(transcript)|ensembl:ENST00000448443(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070971"(endoplasmic reticulum exit site)|mint:Q969M3|ensembl:ENSG00000145817(gene)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:tNd/CdASqK/08G9O9h3nivCTzKw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IXI1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BXS4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-7054441|ensembl:ENSP00000234831|uniprotkb:Q4VBP9|uniprotkb:O75393|intact:MINT-8201752|uniprotkb:Q96KX7|uniprotkb:Q5T705|uniprotkb:B3KQL7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmm59_human(display_long)|uniprotkb:TMEM59(gene name)|psi-mi:TMEM59(display_short)|uniprotkb:C1orf8(gene name synonym)|uniprotkb:Liver membrane-bound protein(gene name synonym)|uniprotkb:HSPC001(orf name)|uniprotkb:UNQ169/PRO195(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001291972.1|refseq:NP_001291978.1|refseq:NP_001291979.1|refseq:NP_001291980.1|refseq:NP_001291981.1|refseq:NP_001291995.1|ensembl:ENSG00000116209(gene)|ensembl:ENST00000234831(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090285"(negative regulation of protein glycosylation in Golgi)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR022065|mint:Q9BXS4|reactome:R-HSA-9013407|reactome:R-HSA-9696273|refseq:NP_004863.2	-	-	comment:mint	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yA2dq3FVXnxw9Peh6f3UBqGzFpM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5L0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5J9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3E5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y266	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UPN7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UI26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UBV2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYU2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYP7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11037623|uniprotkb:Q5TGH5|uniprotkb:F6SH78|uniprotkb:B4DZJ2|uniprotkb:Q59EL3|uniprotkb:Q8NCG4|uniprotkb:Q7L2S5|uniprotkb:Q9UI22|uniprotkb:Q6NXE7|ensembl:ENSP00000306640	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:elov5_human(display_long)|uniprotkb:Very long chain 3-ketoacyl-CoA synthase 5(gene name synonym)|uniprotkb:Very long chain 3-oxoacyl-CoA synthase 5(gene name synonym)|uniprotkb:PRO0530(orf name)|uniprotkb:ELOVL5(gene name)|psi-mi:ELOVL5(display_short)|uniprotkb:3-keto acyl-CoA synthase ELOVL5(gene name synonym)|uniprotkb:ELOVL fatty acid elongase 5(gene name synonym)|uniprotkb:ELOVL2(gene name synonym)|uniprotkb:Fatty acid elongase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001229757.1|refseq:NP_001229759.1|refseq:NP_001229760.1|refseq:NP_001288785.1|refseq:NP_068586.1|ensembl:ENSG00000012660(gene)|ensembl:ENST00000304434(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0016020"(membrane)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0097447"(dendritic tree)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR033677|reactome:R-HSA-2046105|reactome:R-HSA-2046106|reactome:R-HSA-75876	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7kQZS7mYa5eCSOslo4+z9nwtxxk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NXW2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NVI1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H7F0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H4A6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071413.1|ensembl:ENSG00000113384(gene)|ensembl:ENST00000265070(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0009306"(protein secretion)|go:"GO:0010467"(gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9C0E2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BXW9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BTV4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BSJ8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99623	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99442	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-949221|ensembl:ENSP00000337688|ensembl:ENSP00000420331|uniprotkb:O00682|uniprotkb:O00729|intact:EBI-2689278|uniprotkb:D3DNQ0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sec62_human(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:TLOC1(gene name synonym)|uniprotkb:Translocation protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000008952(gene)|ensembl:ENST00000337002(transcript)|ensembl:ENST00000480708(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR004728(Translocation protein Sec62)|rcsb pdb:7BRT|refseq:NP_003253.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:u7na6TjTcixVS+ZK2ygkFA1QDKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96JJ7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96ER3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96DZ1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q92973	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WXD5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WWC4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEX9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TCJ2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8NBX0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8N766	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IXB1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q7L1Q6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6PML9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006336.3|ensembl:ENSG00000014824(gene)|ensembl:ENST00000264451(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|rcsb pdb:2ENK	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P4Q7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11918149|ensembl:ENSP00000366275|uniprotkb:B7Z1U0|uniprotkb:C7SQM3|uniprotkb:C7SQM4|uniprotkb:C7SQM5|uniprotkb:Q53RE5|uniprotkb:Q9H9G3|uniprotkb:Q9HCI0|uniprotkb:Q9NRN1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cnnm4_human(display_long)|uniprotkb:CNNM4(gene name)|psi-mi:CNNM4(display_short)|uniprotkb:ACDP4(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 4(gene name synonym)|uniprotkb:Cyclin-M4(gene name synonym)|uniprotkb:KIAA1592(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000158158(gene)|ensembl:ENST00000377075(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007601"(visual perception)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050896"(response to stimulus)|go:"GO:0055065"(metal ion homeostasis)|go:"GO:0070166"(enamel mineralization)|interpro:IPR000595(Cyclic nucleotide-binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030425"(dendrite)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR018490|interpro:IPR044751|rcsb pdb:6G52|rcsb pdb:6RS2|refseq:NP_064569.3	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sdYQzd8X3Gz9Okurljb9g+Homt89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6NUQ1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5VV42	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5SZE2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262890|ensembl:ENSP00000394012	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5sze2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143418(gene)|ensembl:ENST00000457392(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ka5Rf62LvM6VKgqeYwzYWklPFHc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5JSD2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262088|ensembl:ENSP00000344876	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:q5jsd2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Voltage-dependent anion-selective channel protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000165637(gene)|ensembl:ENST00000344036(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:bVIkbn+i5h7q/vU39RXSmu2/J6A9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5BJH7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q3MHD2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15293	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15006	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14974	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14573	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13438	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q07065	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q00765	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P63167	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62333	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62306	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	intact:EBI-16882364	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	-	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calm1_calm2_calm3_human(display_short)|psi-mi:EBI-16882364(display_long)|intact:CALM(author assigned name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	uniprotkb:P62158(see-also)|uniprotkb:P0DP25(set member)|uniprotkb:P0DP23(set member)|uniprotkb:P0DP24(set member)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	-	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P56381	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3904845|uniprotkb:E1P5H6|uniprotkb:B2RDD0|uniprotkb:Q53XU6|ensembl:ENSP00000243997|ensembl:ENSP00000379019|ensembl:ENSP00000379023	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5e_human(display_long)|uniprotkb:ATP5F1E(gene name)|psi-mi:ATP5F1E(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATP5E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_008817.1|ensembl:ENSG00000124172(gene)|ensembl:ENST00000243997(transcript)|ensembl:ENST00000395659(transcript)|ensembl:ENST00000395663(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:b8qOktspV0v7Gs9uQPpLHf6kLqI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55084	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55072	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P54709	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P52429	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P50402	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P48047	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P43490	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P42695	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40939	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40855	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P36542	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P30154	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P28072	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P27824	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P27797	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P24539	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P20020	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P19388	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P18859	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17931	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17302	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05556	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05026	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P03928	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:YP_003024030.1|ensembl:ENSG00000228253(gene)|ensembl:ENST00000361851(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P02786	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95373	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94905	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94822	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75964	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75947	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75694	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004289.1|refseq:NP_705618.1|ensembl:ENSP00000231498|ensembl:ENST00000381843|ensembl:ENSP00000371265|ensembl:ENSG00000113569(gene)|ensembl:ENST00000231498(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60884	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60613	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1052797|uniprotkb:Q4GZG7|uniprotkb:Q8WU00|uniprotkb:Q9BS64|uniprotkb:Q9GZW0|uniprotkb:Q9NR01|ensembl:ENSP00000328729|uniprotkb:A0A0B4J1S4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sep15_human(display_long)|uniprotkb:SELENOF(gene name)|psi-mi:SELENOF(display_short)|uniprotkb:15 kDa selenoprotein(gene name synonym)|uniprotkb:SEP15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_004252.2|refseq:NP_976086.1|mint:O60613|interpro:IPR039992|ensembl:ENSG00000183291(gene)|ensembl:ENST00000331835(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR014912(Sep15/SelM redox)|interpro:IPR036249|interpro:IPR038219	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:O+C59EK6dpYLDbHWrJT10RtGus89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43819	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43592	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43169	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15397	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15355	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15260	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15173	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14975	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14967	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00487	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00443	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-641094|ensembl:ENSP00000265970|uniprotkb:Q14CQ9|uniprotkb:B4E2G4|uniprotkb:B0LPH2	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:p3c2a_human(display_long)|uniprotkb:Phosphoinositide 3-kinase-C2-alpha(gene name synonym)|uniprotkb:PIK3C2A(gene name)|psi-mi:PIK3C2A(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000011405(gene)|ensembl:ENST00000265970(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0006887"(exocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:NP_001308307.1|refseq:XP_016873413.1|refseq:NP_002636.2|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR001683(Phox-like)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|interpro:IPR037705|interpro:IPR042133|interpro:IPR042236|rcsb pdb:2AR5|rcsb pdb:2IWL|rcsb pdb:2REA|rcsb pdb:2RED|rcsb pdb:6BTY|rcsb pdb:6BTZ|rcsb pdb:6BU0|rcsb pdb:6BUB|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-432722|reactome:R-HSA-8856828|dip:DIP-33727N|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:etm4OwWiGBZtmarHi94o8yW9js89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00410	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00264	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00165	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I3L4P8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I1SRC5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262862	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i1src5_human(display_long)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016740"(transferase activity)|refseq:NP_203524.1|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:JDcLdwWWYYINEC9w5ixJ13LVCHs9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:F8VUA7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JU26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JLW8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JI87	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258875|ensembl:ENSP00000390129	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ji87_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000213585(gene)|ensembl:ENST00000425992(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XQBT9gfVRbapMMX65dSqFGkk7p09606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JGV6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262803|ensembl:ENSP00000404298	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9jgv6_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000099901(gene)|ensembl:ENST00000423859(transcript)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:qjeGKWvXwtiE7cqLu8wKiZ61Z8I9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J2P2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21262793|ensembl:ENSP00000410643	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j2p2_human(display_long)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000105993(gene)|ensembl:ENST00000441561(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PI3kVGcOb+bwk/QBRF7sQDXJvow9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B7ZAQ6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11288340|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:B4DLT3|uniprotkb:B4DXE7|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302|ensembl:ENSP00000319673	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:gphra_human(display_long)|uniprotkb:GPR89A(gene name)|psi-mi:GPR89A(display_short)|uniprotkb:GPHRA(gene name synonym)|uniprotkb:GPR89(gene name synonym)|uniprotkb:Protein GPR89A(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM01(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 90(gene name synonym)|uniprotkb:SH120(gene name synonym)|uniprotkb:CGI-13(orf name)|uniprotkb:UNQ192/PRO218(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001091081.1|refseq:NP_001091082.2|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_005277459.1|refseq:XP_005277461.1|refseq:XP_006711440.1|refseq:XP_006711441.1|refseq:XP_006711555.1|refseq:XP_006711556.1|refseq:XP_011507912.1|refseq:XP_011507914.1|refseq:XP_011508210.1|refseq:XP_011508211.1|refseq:XP_016856937.1|ensembl:ENSG00000117262(gene)|ensembl:ENST00000313835(transcript)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051452"(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B2RWN5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258368	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:A0FGR8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21271805|imex:IM-26691-157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/05/28	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	-	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q9UPN7	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272157|imex:IM-26691-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Suppl. Figure 6g, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:Lg4HDRF5OJYdZCX0OIu5ztIELkY	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q96EY7	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272157|imex:IM-26691-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD	-	-	-	figure legend:Suppl. Figure 6g, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606	rigid:Lg4HDRF5OJYdZCX0OIu5ztIELkY	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q99558	uniprotkb:Q13277	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-1394295|uniprotkb:O43750|uniprotkb:O43751|uniprotkb:Q15360|uniprotkb:B4DME0|ensembl:ENSP00000338562	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:stx3_human(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272157|imex:IM-26691-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	refseq:NP_004168.1|refseq:NP_001171511.1|refseq:XP_005274252.1|refseq:XP_005274257.1|ensembl:ENSG00000166900(gene)|ensembl:ENST00000337979(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR031186|mint:Q13277|reactome:R-HSA-449836	-	-	-	figure legend:Suppl. Figure 6g, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:M/ue1L+l8LnUJNpEWVZ/KWR5UjM9606	rigid:Lg4HDRF5OJYdZCX0OIu5ztIELkY	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P50748	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1001245|uniprotkb:B3KSG2|uniprotkb:A7E2C4|ensembl:ENSP00000328236	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:kntc1_human(display_long)|uniprotkb:Rough deal homolog(gene name synonym)|uniprotkb:KNTC1(gene name)|psi-mi:KNTC1(display_short)|uniprotkb:KIAA0166(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055523.1|ensembl:ENSG00000184445(gene)|ensembl:ENST00000333479(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990423"(RZZ complex)|interpro:IPR019527|interpro:IPR036322|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_006719769.1|dip:DIP-36479N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Fzk1xgK9pVFUAlEHLG3L35X0scU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60566	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1001438|uniprotkb:B2R6U0|uniprotkb:B4DL09|uniprotkb:B4DLG3|uniprotkb:Q59HH6|uniprotkb:Q8WV50|intact:EBI-2551047|uniprotkb:O60501|uniprotkb:O60627|uniprotkb:O60758|uniprotkb:O75389|uniprotkb:Q96KM4|ensembl:ENSP00000287598	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:bub1b_human(display_long)|uniprotkb:MAD3/BUB1-related protein kinase(gene name synonym)|uniprotkb:Mitotic checkpoint kinase MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:Protein SSK1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001202.4|dip:DIP-24203N|ensembl:ENSG00000156970(gene)|ensembl:ENST00000287598(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|mint:O60566|rcsb pdb:2WVI|rcsb pdb:3SI5|rcsb pdb:4GGD|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:5SWF|rcsb pdb:6TLJ|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14545	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1396921|uniprotkb:B4DI89|uniprotkb:A8K5L6|intact:EBI-28969419|ensembl:ENSP00000257604|ensembl:ENSP00000396526	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000257604|ensembl:ENSP00000396526|ensembl:ENST00000552890|ensembl:ENSP00000447340|refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148(gene)|ensembl:ENST00000257604(transcript)|ensembl:ENST00000412615(transcript)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2D9K	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:A2RRP1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056993.2|dip:DIP-56726N|ensembl:ENSG00000151779(gene)|ensembl:ENST00000281513(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR029145|reactome:R-HSA-6811434	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y6G9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2556107|uniprotkb:A2RRG7|uniprotkb:Q53HK7|uniprotkb:Q53HC8|ensembl:ENSP00000273130	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dc1l1_human(display_long)|uniprotkb:DNCLI1(gene name synonym)|uniprotkb:Dynein light intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dynein light chain A(gene name synonym)|uniprotkb:DYNC1LI1(gene name)|psi-mi:DYNC1LI1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057225.2|ensembl:ENSG00000144635(gene)|ensembl:ENST00000273130(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0051301"(cell division)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:Q9Y6G9|rcsb pdb:6B9H|rcsb pdb:6PSD|rcsb pdb:6PSE|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0007018"(microtubule-based movement)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LxQSfBpzuf6Acus2jBy0s53FdhU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y5L0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3T9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y3C1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y2V7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3866319|uniprotkb:Q86V49|uniprotkb:Q5T0U1|uniprotkb:Q9ULT5|uniprotkb:Q6AI19|ensembl:ENSP00000397441	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cog6_human(display_long)|uniprotkb:COG6(gene name)|psi-mi:COG6(display_short)|uniprotkb:KIAA1134(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001138551.1|refseq:NP_065802.1|dip:DIP-48931N|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0070085"(glycosylation)|interpro:IPR010490(Conserved oligomeric complex COG6)|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|ensembl:ENSG00000133103(gene)|ensembl:ENST00000455146(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1S6ym3UxcjqPpQ9WCWf3060I9jE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y277	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9Y241	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UPN7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UP83	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-389502|uniprotkb:A4D0R6|uniprotkb:A4D0R7|uniprotkb:Q6NUL5|uniprotkb:O14555|uniprotkb:O95008|ensembl:ENSP00000297135|ensembl:ENSP00000334703|ensembl:ENSP00000377228	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cog5_human(display_long)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001154992.1|refseq:NP_006339.3|refseq:NP_859422.2|ensembl:ENSG00000164597(gene)|ensembl:ENST00000297135(transcript)|ensembl:ENST00000347053(transcript)|ensembl:ENST00000393603(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR019465|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Jytff1Ttr5vNSps1MeFz2ZoP1Kg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9ULE6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3957166|ensembl:ENSP00000263563|uniprotkb:B2RMS1|uniprotkb:B9EGC6|uniprotkb:Q5JTK7|uniprotkb:Q5JTK8|ensembl:ENST00000263563	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pald_human(display_long)|uniprotkb:PALD1(gene name)|psi-mi:PALD1(display_short)|uniprotkb:KIAA1274(gene name synonym)|uniprotkb:PALD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|ensembl:ENSG00000107719(gene)|ensembl:ENST00000263563(transcript)|refseq:XP_011537939.1|refseq:XP_011537940.1|refseq:NP_055246.2|refseq:XP_016871561.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Qn2qNHC/kC0rsLk68yNNZUrFmc49606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UI26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UGP8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UDR5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1237169|uniprotkb:O95462|ensembl:ENSP00000377040|ensembl:ENSP00000403768|ensembl:ENSP00000505381|ensembl:ENSP00000505958	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:aass_human(display_long)|uniprotkb:AASS(gene name)|psi-mi:AASS(display_short)|uniprotkb:LKR/SDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005754.2|ensembl:ENSG00000008311(gene)|ensembl:ENST00000393376(transcript)|ensembl:ENST00000417368(transcript)|ensembl:ENST00000679511(transcript)|ensembl:ENST00000679864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004753"(saccharopine dehydrogenase activity)|go:"GO:0004754"("saccharopine dehydrogenase (NAD+, L-lysine-forming) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006554"(lysine catabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047130"("saccharopine dehydrogenase (NADP+, L-lysine-forming) activity")|go:"GO:0047131"("saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity")|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR032095|interpro:IPR036291|rcsb pdb:5L76|rcsb pdb:5L78|rcsb pdb:5O1N|rcsb pdb:5O1O|rcsb pdb:5O1P|reactome:R-HSA-71064	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:UKSIs4pNgKcCqgLa0h1pDf1znnQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9UBV2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9P032	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYU2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NYP7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11037623|uniprotkb:Q5TGH5|uniprotkb:F6SH78|uniprotkb:B4DZJ2|uniprotkb:Q59EL3|uniprotkb:Q8NCG4|uniprotkb:Q7L2S5|uniprotkb:Q9UI22|uniprotkb:Q6NXE7|ensembl:ENSP00000306640	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:elov5_human(display_long)|uniprotkb:Very long chain 3-ketoacyl-CoA synthase 5(gene name synonym)|uniprotkb:Very long chain 3-oxoacyl-CoA synthase 5(gene name synonym)|uniprotkb:PRO0530(orf name)|uniprotkb:ELOVL5(gene name)|psi-mi:ELOVL5(display_short)|uniprotkb:3-keto acyl-CoA synthase ELOVL5(gene name synonym)|uniprotkb:ELOVL fatty acid elongase 5(gene name synonym)|uniprotkb:ELOVL2(gene name synonym)|uniprotkb:Fatty acid elongase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001229757.1|refseq:NP_001229759.1|refseq:NP_001229760.1|refseq:NP_001288785.1|refseq:NP_068586.1|ensembl:ENSG00000012660(gene)|ensembl:ENST00000304434(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0016020"(membrane)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0097447"(dendritic tree)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR033677|reactome:R-HSA-2046105|reactome:R-HSA-2046106|reactome:R-HSA-75876	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:7kQZS7mYa5eCSOslo4+z9nwtxxk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NXW2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NVI1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NUQ9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1055930|uniprotkb:Q96AZ5|uniprotkb:Q9NZE7|uniprotkb:Q9NW21|ensembl:ENSP00000384880|ensembl:ENSP00000428117|ensembl:ENSP00000429078|ensembl:ENSP00000429150|ensembl:ENSP00000429499|ensembl:ENSP00000429802|ensembl:ENSP00000430674	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cyrib_human(display_long)|uniprotkb:CYRIB(gene name)|psi-mi:CYRIB(display_short)|uniprotkb:CYRI(gene name synonym)|uniprotkb:FAM49B(gene name synonym)|uniprotkb:L1(gene name synonym)|uniprotkb:BM-009(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011515410.1|refseq:XP_011515411.1|refseq:XP_011515412.1|refseq:XP_011515413.1|refseq:XP_011515415.1|refseq:XP_011515414.1|refseq:NP_001243692.1|refseq:XP_011515416.1|refseq:XP_011515417.1|refseq:XP_011515423.1|refseq:XP_011515424.1|refseq:XP_011515425.1|refseq:XP_011515426.1|refseq:XP_011515427.1|refseq:NP_057707.3|ensembl:ENSG00000153310(gene)|ensembl:ENST00000401979(transcript)|ensembl:ENST00000517654(transcript)|ensembl:ENST00000519110(transcript)|ensembl:ENST00000519540(transcript)|ensembl:ENST00000519824(transcript)|ensembl:ENST00000522746(transcript)|ensembl:ENST00000523509(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0023030"(MHC class Ib protein binding, via antigen binding groove)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000568"(positive regulation of memory T cell activation)|interpro:IPR009828(Protein of unknown function DUF1394)|interpro:IPR039789|rcsb pdb:7AJK|reactome:R-HSA-114608|refseq:NP_001317541.1|refseq:XP_016869028.1|refseq:XP_016869029.1|refseq:XP_016869030.1|refseq:XP_016869031.1|refseq:XP_016869032.1|refseq:XP_016869033.1|refseq:XP_016869034.1|refseq:XP_016869035.1|refseq:XP_016869036.1|refseq:XP_016869037.1|refseq:XP_016869038.1|refseq:XP_016869039.1|refseq:XP_016869040.1|refseq:XP_016869047.1|refseq:XP_016869048.1|refseq:XP_016869049.1|refseq:XP_016869050.1|refseq:XP_016869051.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:x123Rh78yRGOGEgYIBIm/a+45ss9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NRZ9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1056215|uniprotkb:Q3LID1|uniprotkb:Q6I7N7|uniprotkb:Q76H76|uniprotkb:Q76H77|uniprotkb:Q76H78|uniprotkb:Q76H79|uniprotkb:Q76H80|uniprotkb:Q76H81|uniprotkb:Q7Z397|uniprotkb:Q7Z5X2|uniprotkb:Q8N6P4|uniprotkb:Q9H4P5|uniprotkb:B2RB41|ensembl:ENSP00000239027	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hells_human(display_long)|uniprotkb:HELLS(gene name)|psi-mi:HELLS(display_short)|uniprotkb:SMARCA6(gene name synonym)|uniprotkb:PASG(gene name synonym)|uniprotkb:Nbla10143(orf name)|uniprotkb:SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6(gene name synonym)|uniprotkb:Proliferation-associated SNF2-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060533.2|refseq:NP_001275996.1|refseq:NP_001275997.1|refseq:NP_001275998.1|refseq:NP_001275999.1|refseq:NP_001276000.1|refseq:NP_001276001.1|refseq:NP_001276002.1|refseq:NP_001276003.1|refseq:NP_001276004.1|ensembl:ENSG00000119969(gene)|ensembl:ENST00000348459(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001655"(urogenital system development)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044753|mint:Q9NRZ9	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QhCAini69BkBNF7TwsA0pflATBk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9NP97	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-372128|uniprotkb:Q5TC72|uniprotkb:Q96IV3|uniprotkb:Q9NQM2|uniprotkb:B1AKR5|ensembl:ENSP00000349679	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dlrb1_human(display_long)|uniprotkb:DYNLRB1(gene name)|psi-mi:DYNLRB1(display_short)|uniprotkb:BITH(gene name synonym)|uniprotkb:DNLC2A(gene name synonym)|uniprotkb:HSPC162(orf name)|uniprotkb:Dynein light chain 2A, cytoplasmic(gene name synonym)|uniprotkb:Dynein-associated protein Km23(gene name synonym)|uniprotkb:Bithoraxoid-like protein(gene name synonym)|uniprotkb:DNCL2A(gene name synonym)|uniprotkb:ROBLD1(gene name synonym)|uniprotkb:Roadblock domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_054902.1|refseq:NP_001268656.1|refseq:NP_001268657.1|refseq:NP_001268658.1|refseq:NP_808852.1|rcsb pdb:2HZ5|rcsb pdb:6F1T|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6RLB|rcsb pdb:6SC2|reactome:R-HSA-5620924|rcsb pdb:2E8J|ensembl:ENSG00000125971(gene)|ensembl:ENST00000357156(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0097542"(ciliary tip)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|rcsb pdb:1Z09|rcsb pdb:2B95	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:jUoW69LtAjTLlqS8J8KH7nImOSQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H974	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1221028|uniprotkb:Q6IA59|uniprotkb:A6NGE9|uniprotkb:B7Z472|uniprotkb:B7Z5R2|uniprotkb:J3KR78|ensembl:ENSP00000281273	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:qtrt2_human(display_long)|uniprotkb:Queuine tRNA-ribosyltransferase domain-containing protein 1(gene name synonym)|uniprotkb:QTRT2(gene name)|psi-mi:QTRT2(display_short)|uniprotkb:QTRTD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078914.1|refseq:NP_001243764.1|refseq:NP_001243765.1|refseq:NP_001243766.1|refseq:XP_005247827.1|refseq:XP_016862671.1|refseq:XP_016862672.1|ensembl:ENSG00000151576(gene)|ensembl:ENST00000281273(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008479"(queuine tRNA-ribosyltransferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0101030"(tRNA-guanine transglycosylation)|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|interpro:IPR028592|interpro:IPR036511|reactome:R-HSA-6782315	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8OQIoDPH8P/UdGe3VQO9/4KdpFs9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H845	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H446	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-748952|uniprotkb:Q9Y313|uniprotkb:Q9Y6B3|uniprotkb:A8K3W2|uniprotkb:A8MT24|ensembl:ENSP00000420357	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rwdd1_human(display_long)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:RWDD1(gene name)|psi-mi:RWDD1(display_short)|uniprotkb:CGI-24(orf name)|uniprotkb:PTD013(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057036.2|refseq:NP_001007465.1|refseq:NP_057188.2|ensembl:ENST00000466444(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005844"(polysome)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|ensembl:ENSG00000111832(gene)|interpro:IPR040213|rcsb pdb:2EBM|interpro:IPR032378|dip:DIP-34520N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OvfJFwoLwchgGBS56iOdvVs0TDg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9H078	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9C0E2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BXW9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BVI4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395927|uniprotkb:Q8N2S5|uniprotkb:Q96I14|ensembl:ENSP00000328854|ensembl:ENSP00000500901	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:noc4l_human(display_long)|uniprotkb:NOC4-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 4-like protein(gene name synonym)|uniprotkb:NOC4L(gene name)|psi-mi:NOC4L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_076983.1|ensembl:ENSG00000184967(gene)|ensembl:ENSG00000288146(gene)|ensembl:ENST00000330579(transcript)|ensembl:ENST00000672504(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027193|mint:Q9BVI4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-32938N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PczuDyeVf4oAGktQfOSfHWmrCwA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BTX1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q9BTT0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401(gene)|ensembl:ENST00000583931(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99832	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99523	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057058|uniprotkb:Q8IZ49|uniprotkb:C0JYZ0|uniprotkb:B4DWI3|ensembl:ENSP00000256637	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sort_human(display_long)|uniprotkb:SORT1(gene name)|psi-mi:SORT1(display_short)|uniprotkb:Neurotensin receptor 3(gene name synonym)|uniprotkb:Glycoprotein 95(gene name synonym)|uniprotkb:100 kDa NT receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001192157.1|refseq:NP_002950.3|ensembl:ENSG00000134243(gene)|ensembl:ENST00000256637(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010465"(nerve growth factor receptor activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030379"(neurotensin receptor activity, non-G protein-coupled)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046323"(glucose import)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1905394"(retromer complex binding)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|mint:Q99523|rcsb pdb:3F6K|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:4MSL|rcsb pdb:4N7E|rcsb pdb:4PO7|rcsb pdb:5MRH|rcsb pdb:5MRI|rcsb pdb:6EHO|rcsb pdb:6X3L|rcsb pdb:6X48|rcsb pdb:6X4H|reactome:R-HSA-432722|go:"GO:0032868"(response to insulin)|dip:DIP-41798N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:h/+2jen/dw+5leVis906F7iBs/A9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q99442	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-949221|ensembl:ENSP00000337688|ensembl:ENSP00000420331|uniprotkb:O00682|uniprotkb:O00729|intact:EBI-2689278|uniprotkb:D3DNQ0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:sec62_human(display_long)|uniprotkb:SEC62(gene name)|psi-mi:SEC62(display_short)|uniprotkb:TLOC1(gene name synonym)|uniprotkb:Translocation protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000008952(gene)|ensembl:ENST00000337002(transcript)|ensembl:ENST00000480708(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR004728(Translocation protein Sec62)|rcsb pdb:7BRT|refseq:NP_003253.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:u7na6TjTcixVS+ZK2ygkFA1QDKY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96SK2	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-10963859|ensembl:ENSP00000380747|uniprotkb:Q6PF00|uniprotkb:Q96SL6|uniprotkb:A4D1L1|uniprotkb:Q8NCH3|uniprotkb:Q49A50	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tm209_human(display_long)|uniprotkb:TMEM209(gene name)|psi-mi:TMEM209(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001288092.1|refseq:NP_116231.2|refseq:XP_005250712.1|refseq:XP_011514948.1|ensembl:ENSG00000146842(gene)|ensembl:ENST00000397622(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019176	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LJ052UMkTP09EJVErI5qnsGxmJs9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96KC8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96KA5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96JJ7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96EK5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-744150|uniprotkb:A8K5M8|uniprotkb:Q9BR89|uniprotkb:Q9ULE1|uniprotkb:Q9Y428|ensembl:ENSP00000354848	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:kbp_human(display_long)|uniprotkb:KIF1-binding protein(gene name synonym)|uniprotkb:Kinesin family binding protein(gene name synonym)|uniprotkb:KBP(gene name synonym)|uniprotkb:KIAA1279(gene name synonym)|uniprotkb:KIFBP(gene name)|psi-mi:KIFBP(display_short)|uniprotkb:KIF1BP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056449.1|ensembl:ENSG00000198954(gene)|ensembl:ENST00000361983(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007399"(nervous system development)|go:"GO:0019894"(kinesin binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR022083|mint:Q96EK5|rcsb pdb:6ZPG|rcsb pdb:6ZPH	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:wiRR4tDx91/cAUb2ANX42T+vhyI9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96CN4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q96AQ6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q969S3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2687480|ensembl:ENSP00000310042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_219482.1|ensembl:ENSG00000173545(gene)|ensembl:ENST00000308683(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q92572	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4289921|uniprotkb:Q6ICQ2|uniprotkb:O00676|uniprotkb:O00727|uniprotkb:Q53XL4|uniprotkb:O00647|uniprotkb:O00721|ensembl:ENSP00000325369	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ap3s1_human(display_long)|uniprotkb:AP3S1(gene name)|psi-mi:AP3S1(display_short)|uniprotkb:Sigma-3A-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3a(gene name synonym)|uniprotkb:CLAPS3(gene name synonym)|uniprotkb:AP-3 complex subunit sigma-3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit sigma-1(gene name synonym)|uniprotkb:Clathrin-associated/assembly/adaptor protein, small 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000177879(gene)|ensembl:ENST00000316788(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027155|reactome:R-HSA-432722|refseq:NP_001275.1|refseq:NP_001002924.2|refseq:NP_001305019.1|refseq:NP_001305020.1|refseq:NP_001305022.1|refseq:NP_001305023.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:fRNNY4ETqt4Qv6CTQqFxeIk8Syc9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q92504	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1051105|uniprotkb:Q5STP8|uniprotkb:Q9UIQ0|uniprotkb:B0UXF6|ensembl:ENSP00000363807|ensembl:ENSP00000363809|ensembl:ENSP00000372700|ensembl:ENSP00000372701|ensembl:ENSP00000389623|ensembl:ENSP00000391735|ensembl:ENSP00000403583|ensembl:ENSP00000407093|ensembl:ENSP00000410656|ensembl:ENSP00000413027|ensembl:ENSP00000414145|ensembl:ENSP00000416439	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s39a7_human(display_long)|uniprotkb:Solute carrier family 39 member 7(gene name synonym)|uniprotkb:Histidine-rich membrane protein Ke4(gene name synonym)|uniprotkb:SLC39A7(gene name)|psi-mi:SLC39A7(display_short)|uniprotkb:HKE4(gene name synonym)|uniprotkb:RING5(gene name synonym)|uniprotkb:Zrt-, Irt-like protein 7(gene name synonym)|uniprotkb:Really interesting new gene 5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001070984.1|refseq:NP_008910.2|refseq:NP_001275706.1|ensembl:ENSG00000112473(gene)|ensembl:ENSG00000206288(gene)|ensembl:ENSG00000224399(gene)|ensembl:ENSG00000226614(gene)|ensembl:ENSG00000227402(gene)|ensembl:ENSG00000229802(gene)|ensembl:ENST00000374675(transcript)|ensembl:ENST00000374677(transcript)|ensembl:ENST00000383213(transcript)|ensembl:ENST00000383214(transcript)|ensembl:ENST00000416369(transcript)|ensembl:ENST00000418477(transcript)|ensembl:ENST00000423043(transcript)|ensembl:ENST00000441854(transcript)|ensembl:ENST00000441953(transcript)|ensembl:ENST00000443773(transcript)|ensembl:ENST00000456261(transcript)|ensembl:ENST00000431735(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR003689(Zinc/iron permease)|mint:Q92504|reactome:R-HSA-442380	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:br+gKDgDx3uyEg/kbJ6JCqJaTXA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8WUY1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1170414|uniprotkb:Q8NBN2|uniprotkb:Q9NYI2|uniprotkb:B2RDN6|intact:EBI-2563242|ensembl:ENSP00000338607	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:them6_human(display_long)|uniprotkb:THEM6(gene name)|psi-mi:THEM6(display_short)|uniprotkb:C8orf55(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSCD75(gene name synonym)|uniprotkb:Thioesterase superfamily member 6(gene name synonym)|uniprotkb:PSEC0098(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_057731.1|ensembl:ENSG00000130193(gene)|ensembl:ENST00000336138(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR029069	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VCZRUm2WiwLdWnKB8jTuOvLy+4A9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEX9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TEM1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TCG1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8TAT6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1994109|uniprotkb:Q8N3J1|uniprotkb:Q9H8V2|uniprotkb:Q9H964|uniprotkb:Q9NWR5|uniprotkb:Q9P229|ensembl:ENSP00000331487	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:npl4_human(display_long)|uniprotkb:NPLOC4(gene name)|psi-mi:NPLOC4(display_short)|uniprotkb:KIAA1499(gene name synonym)|uniprotkb:NPL4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011523281.1|refseq:NP_060391.2|dip:DIP-44059N|ensembl:ENSG00000182446(gene)|ensembl:ENST00000331134(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036501"(UFD1-NPL4 complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR007716(NPL4, zinc-binding putative)|interpro:IPR007717(NPL4)|interpro:IPR016563(Polyubiquitin-tagged protein recognition complex, Npl4 component)|interpro:IPR024682|interpro:IPR029071|interpro:IPR036443|interpro:IPR037518|mint:Q8TAT6|reactome:R-HSA-110320	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:GXRNmG7yqEf5aFMo7yPDih93yfk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8N766	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q8IUR0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3246160|ensembl:ENSP00000316990|ensembl:ENSP00000399025|ensembl:ENSP00000470262|uniprotkb:A8K7I6	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tppc5_human(display_long)|uniprotkb:TRAPPC5(gene name)|psi-mi:TRAPPC5(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000181029(gene)|ensembl:ENST00000317378(transcript)|ensembl:ENST00000596148(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016696(TRAPP I complex, Trs31)|interpro:IPR024096|reactome:R-HSA-204005|reactome:R-HSA-8876198|ensembl:ENST00000426877(transcript)|refseq:NP_001035926.1|refseq:NP_001035927.1|refseq:NP_777554.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:mojNHWAAx2Vj20UWUjm0UJsHxnQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q86U38	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5456022|uniprotkb:Q8IVF0|uniprotkb:Q8TBS6|intact:EBI-8293740|intact:MINT-8407174|uniprotkb:A8MY76|ensembl:ENSP00000267425|ensembl:ENSP00000495668	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nop9_human(display_long)|uniprotkb:NOP9(gene name)|psi-mi:NOP9(display_short)|uniprotkb:C14orf21(gene name synonym)|uniprotkb:KIAA2021(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001273296.1|refseq:NP_777573.1|ensembl:ENSG00000196943(gene)|ensembl:ENSG00000285326(gene)|ensembl:ENST00000267425(transcript)|ensembl:ENST00000644840(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040000|mint:Q86U38	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:dJjEtwyK4x6qVx2dW0MzS7tqDYI9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q7RTS9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2871106|uniprotkb:A8K5I8|uniprotkb:Q3ZTS8|uniprotkb:Q9NPU7|uniprotkb:Q6P2P5|uniprotkb:B4DKI7|uniprotkb:Q9BVE9|uniprotkb:B2RCF9|uniprotkb:Q8N2M0|ensembl:ENSP00000269445	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dym_human(display_long)|uniprotkb:DYM(gene name)|psi-mi:DYM(display_short)|uniprotkb:Dyggve-Melchior-Clausen syndrome protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_060123.3|ensembl:ENSG00000141627(gene)|ensembl:ENST00000269445(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0060348"(bone development)|interpro:IPR019142	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4o4oPqyjY7dKe5VV26gDM6rXIFM9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q7L1Q6	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6PML9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006336.3|ensembl:ENSG00000014824(gene)|ensembl:ENST00000264451(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|rcsb pdb:2ENK	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P3X3	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057046|uniprotkb:A6NKJ0|uniprotkb:Q96SS5|uniprotkb:Q9BVF1|uniprotkb:Q9NWR4|uniprotkb:Q9NXG4|ensembl:ENSP00000313953	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ttc27_human(display_long)|uniprotkb:TTC27(gene name)|psi-mi:TTC27(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001180438.1|refseq:NP_060205.3|ensembl:ENSG00000018699(gene)|ensembl:ENST00000317907(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR044244|mint:Q6P3X3	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LvE8UTgFaNjAZEkxCnmPTr/YP+Q9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q6P1M0	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q66K14	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2688824|uniprotkb:O75163|uniprotkb:D3DWQ6|uniprotkb:Q96H49|uniprotkb:Q6MZI2|uniprotkb:Q53EY0|uniprotkb:D3DWQ5|ensembl:ENSP00000349291|ensembl:ENSP00000491373|ensembl:ENSP00000491970	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tbc9b_human(display_long)|uniprotkb:KIAA0676(gene name synonym)|uniprotkb:TBC1D9B(gene name)|psi-mi:TBC1D9B(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055858.2|refseq:NP_942568.2|ensembl:ENSG00000197226(gene)|ensembl:ENSG00000284400(gene)|ensembl:ENST00000356834(transcript)|ensembl:ENST00000639361(transcript)|ensembl:ENST00000639711(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR004182(GRAM)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035969|interpro:IPR036014|interpro:IPR036017|mint:Q66K14	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DdCLCQa69pLYH6eIKdazflUwAKY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q5BJH7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q16822	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780|ensembl:ENSP00000494919|uniprotkb:B4DW73	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_001018083.2|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0042594"(response to starvation)|go:"GO:0046327"(glycerol biosynthetic process from pyruvate)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|go:"GO:0030145"(manganese ion binding)|ensembl:ENSG00000100889(gene)|ensembl:ENSG00000285241(gene)|ensembl:ENST00000216780(transcript)|ensembl:ENST00000645217(transcript)|go:"GO:0004611"(phosphoenolpyruvate carboxykinase activity)|go:"GO:0004613"("phosphoenolpyruvate carboxykinase (GTP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019543"(propionate catabolic process)|refseq:NP_004554.3	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15386	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15366	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15293	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q15155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14974	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q14139	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1048119|uniprotkb:Q2M1H0|uniprotkb:Q6P5T4|uniprotkb:Q7Z639|uniprotkb:B0YJB6|ensembl:ENSP00000252108	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ube4a_human(display_long)|uniprotkb:UBE4A(gene name)|psi-mi:UBE4A(display_short)|uniprotkb:KIAA0126(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4 A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001191006.1|refseq:NP_004779.2|ensembl:ENSG00000110344(gene)|ensembl:ENST00000252108(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019474|rcsb pdb:1WGM|reactome:R-HSA-983168	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:nk+uYWQ8ytS/qOjUkCDf9dAymPU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13451	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-306914|ensembl:ENSP00000349811|ensembl:ENSP00000441205|ensembl:ENSP00000444810|uniprotkb:Q5TGM6|uniprotkb:F5H7R1|uniprotkb:Q59EB8	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:fkbp5_human(display_long)|uniprotkb:FKBP5(gene name)|psi-mi:FKBP5(display_short)|uniprotkb:AIG6(gene name synonym)|uniprotkb:FKBP51(gene name synonym)|uniprotkb:FK506-binding protein 5(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:54 kDa progesterone receptor-associated immunophilin(gene name synonym)|uniprotkb:FKBP54(gene name synonym)|uniprotkb:FF1 antigen(gene name synonym)|uniprotkb:HSP90-binding immunophilin(gene name synonym)|uniprotkb:Androgen-regulated protein 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000096060(gene)|ensembl:ENST00000357266(transcript)|ensembl:ENST00000536438(transcript)|ensembl:ENST00000539068(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|refseq:NP_001139247.1|refseq:NP_001139248.1|refseq:NP_004108.1|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031210|mint:Q13451|rcsb pdb:1KT0|rcsb pdb:3O5D|rcsb pdb:3O5E|rcsb pdb:3O5F|rcsb pdb:3O5G|rcsb pdb:3O5I|rcsb pdb:3O5J|rcsb pdb:3O5K|rcsb pdb:3O5L|rcsb pdb:3O5M|rcsb pdb:3O5O|rcsb pdb:3O5P|rcsb pdb:3O5Q|rcsb pdb:3O5R|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRK|rcsb pdb:4DRM|rcsb pdb:4DRN|rcsb pdb:4DRO|rcsb pdb:4DRP|rcsb pdb:4DRQ|rcsb pdb:4JFI|rcsb pdb:4JFJ|rcsb pdb:4JFK|rcsb pdb:4JFL|rcsb pdb:4JFM|rcsb pdb:4R0X|rcsb pdb:4TW6|rcsb pdb:4TW7|rcsb pdb:4TX0|rcsb pdb:4W9O|rcsb pdb:4W9P|rcsb pdb:4W9Q|rcsb pdb:5BXJ|rcsb pdb:5DIT|rcsb pdb:5DIU|rcsb pdb:5DIV|rcsb pdb:5NJX|rcsb pdb:5OBK|rcsb pdb:5OMP|rcsb pdb:6SAF|rcsb pdb:6TX4|rcsb pdb:6TX5|rcsb pdb:6TX6|rcsb pdb:6TX7|rcsb pdb:6TX8|rcsb pdb:6TX9|rcsb pdb:6TXX|rcsb pdb:7A6W|rcsb pdb:7A6X|rcsb pdb:7AOT|rcsb pdb:7AOU|rcsb pdb:7AWF|rcsb pdb:7AWX|rcsb pdb:7B9Y|rcsb pdb:7B9Z|rcsb pdb:7BA0|reactome:R-HSA-3371497|reactome:R-HSA-8939211|reactome:R-HSA-9022699|refseq:NP_001139249.1|dip:DIP-27597N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:m2Bnn01E13sovh3BwG71Pgqjdx89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13438	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q13015	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-6269719|ensembl:ENSP00000357917	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q08380	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q04917	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:Q01105	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P83436	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-389534|uniprotkb:Q6UWU7|ensembl:ENSP00000305442	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cog7_human(display_long)|uniprotkb:UNQ3082/PRO10013(orf name)|uniprotkb:COG7(gene name)|psi-mi:COG7(display_short)|uniprotkb:Component of oligomeric Golgi complex 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_705831.1|ensembl:ENSG00000168434(gene)|ensembl:ENST00000307149(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050821"(protein stabilization)|interpro:IPR019335|mint:P83436|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:H0hZTc8M4oCkuEUCOMEMJ122BeY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P82914	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P78527	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P62333	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P60510	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P56381	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3904845|uniprotkb:E1P5H6|uniprotkb:B2RDD0|uniprotkb:Q53XU6|ensembl:ENSP00000243997|ensembl:ENSP00000379019|ensembl:ENSP00000379023	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5e_human(display_long)|uniprotkb:ATP5F1E(gene name)|psi-mi:ATP5F1E(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATP5E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_008817.1|ensembl:ENSG00000124172(gene)|ensembl:ENST00000243997(transcript)|ensembl:ENST00000395659(transcript)|ensembl:ENST00000395663(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:b8qOktspV0v7Gs9uQPpLHf6kLqI9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55084	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P55072	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P54709	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P52429	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1057499|uniprotkb:Q9UKQ3|uniprotkb:Q8TBM4|ensembl:ENSP00000284061	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dgke_human(display_long)|uniprotkb:DGKE(gene name)|psi-mi:DGKE(display_short)|uniprotkb:DAGK5(gene name synonym)|uniprotkb:Diglyceride kinase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003638.1|ensembl:ENSG00000153933(gene)|ensembl:ENST00000284061(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0030168"(platelet activation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|reactome:R-HSA-114508	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Fh3ky/ncwvXmjfiyJTdn5HTLRk89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P51812	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1046616|ensembl:ENSP00000368884|uniprotkb:Q4VAP3|uniprotkb:Q59H26|uniprotkb:Q5JPK8|uniprotkb:Q7Z3Z7|uniprotkb:B2R9V4	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ks6a3_human(display_long)|uniprotkb:Insulin-stimulated protein kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1b(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 3(gene name synonym)|uniprotkb:MAPKAPK1B(gene name synonym)|uniprotkb:Ribosomal S6 kinase 2(gene name synonym)|uniprotkb:pp90RSK2(gene name synonym)|uniprotkb:RPS6KA3(gene name)|psi-mi:RPS6KA3(display_short)|uniprotkb:ISPK1(gene name synonym)|uniprotkb:RSK2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043555"(regulation of translation in response to stress)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045202"(synapse)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|ensembl:ENSG00000177189(gene)|ensembl:ENST00000379565(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_004577.1|interpro:IPR041905|interpro:IPR041906|mint:P51812|rcsb pdb:4D9T|rcsb pdb:4D9U|rcsb pdb:4JG6|rcsb pdb:4JG7|rcsb pdb:4JG8|rcsb pdb:4NUS|rcsb pdb:4NW5|rcsb pdb:4NW6|rcsb pdb:5D9K|rcsb pdb:5D9L|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|dip:DIP-38247N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:zkX8NPvSEjVEap7TxboH2SKy9zg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P48047	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P46977	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P43490	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P40939	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P36873	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P36542	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P31946	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P31689	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P27824	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P24539	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P20020	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P19388	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P18859	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P17302	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P16401	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5327611|uniprotkb:Q14529|uniprotkb:Q3MJ42|ensembl:ENSP00000330074	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:h15_human(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1F5(gene name synonym)|uniprotkb:HIST1H1B(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005313.1|ensembl:ENSG00000184357(gene)|ensembl:ENST00000331442(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0050821"(protein stabilization)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2FE2|rcsb pdb:2RHI|reactome:R-HSA-140342|reactome:R-HSA-2559584|go:"GO:0000792"(heterochromatin)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:b81Z7VA09Na0XXDfR0HtaZmq1g89606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:P05026	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O95373	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94829	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O94822	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O75155	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60884	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O60447	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-852291|uniprotkb:A6NKX8|uniprotkb:Q9H1Y9|uniprotkb:B9A6J0|intact:EBI-28983653|ensembl:ENSP00000359356	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:evi5_human(display_long)|uniprotkb:Neuroblastoma stage 4S gene protein(gene name synonym)|uniprotkb:EVI5(gene name)|psi-mi:EVI5(display_short)|uniprotkb:NB4S(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_005656.4|ensembl:ENSP00000359356|ensembl:ENST00000540033|ensembl:ENSP00000440826|refseq:NP_001295177.1|dip:DIP-38024N|ensembl:ENSG00000067208(gene)|ensembl:ENST00000370331(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:EyooNakM1gos/ADyryAHwuQPhZk9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O43592	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15397	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15355	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O15120	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-3935937|uniprotkb:Q9BWR7|uniprotkb:O00516|uniprotkb:Q5VUD4|uniprotkb:Q9BSV7|uniprotkb:O15106|uniprotkb:Q5VUD3|intact:EBI-28988552|ensembl:ENSP00000360761|ensembl:ENSP00000438919	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:plcb_human(display_long)|uniprotkb:AGPAT2(gene name)|psi-mi:AGPAT2(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 2(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001012745.1|refseq:NP_006403.2|ensembl:ENST00000371694|ensembl:ENSP00000360759|ensembl:ENSP00000360761|ensembl:ENSP00000438919|ensembl:ENSG00000169692(gene)|ensembl:ENST00000371696(transcript)|ensembl:ENST00000538402(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-HSA-1483166|reactome:R-HSA-6798695	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:quJFJpDvkJbjDx+PiTqRDpLfqzg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14828	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O14579	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:O00165	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:J3KTC1	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21272186|ensembl:ENSP00000462914	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:j3ktc1_human(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000153944(gene)|ensembl:ENST00000579590(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034130|interpro:IPR035979	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:+hXuQvt+2872afMykHRCsA7eUAg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I3L4P8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258949|ensembl:ENSP00000461428|ensembl:ENSP00000487635|uniprotkb:A0A0A6YYS0|uniprotkb:A0A0K0K1G7|uniprotkb:I3L1G7	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i3l4p8_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000574466(transcript)|ensembl:ENST00000633088(transcript)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0006788"(heme oxidation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:0+JIee31O8Qsqy8G4wRPm7YQeuQ9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:I3L192	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21264369|ensembl:ENSP00000458665	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:i3l192_human(display_long)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000172270(gene)|ensembl:ENST00000573216(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:s2h7cByi0kSTLQepPGxFhBMisl09606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:F8VUA7	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258914|ensembl:ENSP00000447893	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:f8vua7_human(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000091039(gene)|ensembl:ENST00000546946(transcript)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:FpjhGNnuGyWYlRyfPBAo9Z6JAyw9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:E9PBL8	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-10979568|ensembl:ENSP00000400111	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:e9pbl8_human(display_long)|uniprotkb:COG1(gene name)|psi-mi:COG1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000166685(gene)|ensembl:ENST00000438720(transcript)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017119"(Golgi transport complex)|interpro:IPR033370	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:/5Fg3wpubnf7vEHOAY8IemiNnBE9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:D6RIU4	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21266740|ensembl:ENSP00000427377	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:d6riu4_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000169223(gene)|ensembl:ENST00000513877(transcript)|go:"GO:0016020"(membrane)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:ujH+pk/DX0l/Q0WbBMfD6c/kRJc9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9JU26	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260354|ensembl:ENSP00000407540	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9ju26_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase subunit f, mitochondrial(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000241468(gene)|ensembl:ENST00000449683(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR019344	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:hTGlvq8vafbNgObo1xHtT8e+bGY9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:C9J6N9	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21260344|ensembl:ENSP00000418390	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:c9j6n9_human(display_long)|uniprotkb:UFD1(gene name)|psi-mi:UFD1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000070010(gene)|ensembl:ENST00000494054(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:YU/1QUJAWyW8kHeChAhsIDH0U609606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:B2RWN5	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21258368	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:b2rwn5_human(display_long)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|refseq:NP_060542.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR022125|interpro:IPR040191	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:Az5IY7d03OnoFLLV6nhzdsnreJg9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15077	uniprotkb:A0A087WZ13	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-21272173|ensembl:ENSP00000482277	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:a0a087wz13_human(display_long)|uniprotkb:RAVER1(gene name)|psi-mi:RAVER1(display_short)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21272198|imex:IM-26691-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSG00000161847(gene)|ensembl:ENST00000617231(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979	-	-	-	figure legend:Figure 6d, Figure 6e, Suppl. Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2019/01/08	2019/03/18	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:z9bfFoZ7eLFzEY4FgDr4HtkmUNU9606	rigid:Yxi8GWeTqr6AZINQJzxGvjkDVOQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15646	uniprotkb:Q4G0J3	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|uniprotkb:B2RAZ2|uniprotkb:I1YDD2|ensembl:ENSP00000257570	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273459|imex:IM-26691-175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003724.1|refseq:NP_001248754.1|refseq:NP_937856.1|ensembl:ENSG00000135114(gene)|ensembl:ENST00000257570(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:XP_016875630.1	refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12	-	-	-	figure legend:Suppl. fig. 2d.i|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/15	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	rigid:bIZud6xLFyodOUsrG/SMtVV3vv8	false	tandem tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96C10	uniprotkb:Q16666	intact:EBI-744193|uniprotkb:Q9HAM6|ensembl:ENSP00000251642	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809	psi-mi:dhx58_human(display_long)|uniprotkb:Probable ATP-dependent helicase LGP2(gene name synonym)|uniprotkb:Protein D11Lgp2 homolog(gene name synonym)|uniprotkb:DHX58(gene name)|psi-mi:DHX58(display_short)|uniprotkb:D11LGP2E(gene name synonym)|uniprotkb:LGP2(gene name synonym)|uniprotkb:RIG-I-like receptor LGP2(gene name synonym)|uniprotkb:RIG-I-like receptor 3(gene name synonym)	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273721|imex:IM-26691-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077024.2|ensembl:ENSG00000108771(gene)|ensembl:ENST00000251642(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQA|rcsb pdb:2W4R|rcsb pdb:3EQT|reactome:R-HSA-168928|go:"GO:0045824"(negative regulation of innate immune response)|refseq:XP_016880548.1|refseq:XP_016880549.1|dip:DIP-60792N	refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENST00000295809(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042149"(cellular response to glucose starvation)|ensembl:ENSG00000163565(gene)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|reactome:R-HSA-1834941|reactome:R-HSA-3270619	-	-	-	figure legend:Suppl. fig. 2d.ii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:CSy2ThXaTTCmqGNqf8LrJvUXIBA9606	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	rigid:MZtN6iPDM3/la/prIWgS8b/hFNM	false	tandem tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y3I0	uniprotkb:Q9Y224	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	intact:EBI-1104547|ensembl:ENSP00000261700	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273731|imex:IM-26691-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531	-	-	-	figure legend:Suppl. fig. 2d.iii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	rigid:3iBPZ4oxbiCfBv7f1kOoER232kE	false	tandem tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IY21	uniprotkb:P60228	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273741|imex:IM-26691-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060101.3|ensembl:ENSG00000137628(gene)|ensembl:ENST00000393743(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Suppl. fig. 2d.iv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	rigid:bgd48UtUCsYZXiYAzpedUxyOXOA	false	tandem tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P04233	uniprotkb:P60228	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273751|imex:IM-26691-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Suppl. fig. 2d.v|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	rigid:thfINVnIhpBgHlYQlBHUBkYdIpc	false	tandem tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96JQ5	uniprotkb:P55060	intact:EBI-12820341|ensembl:ENSP00000338648|uniprotkb:Q8TEZ6|uniprotkb:Q96PG7|uniprotkb:Q9BY18|uniprotkb:Q9H3V3|uniprotkb:Q9P1S3	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:m4a4a_human(display_long)|uniprotkb:MS4A4A(gene name)|psi-mi:MS4A4A(display_short)|uniprotkb:4SPAN1(gene name synonym)|uniprotkb:CD20 antigen-like 1(gene name synonym)|uniprotkb:CD20L1(gene name synonym)|uniprotkb:Four-span transmembrane protein 1(gene name synonym)|uniprotkb:MS4A4(gene name synonym)|uniprotkb:HDCME31P(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273774|imex:IM-26691-189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110079(gene)|ensembl:ENST00000337908(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|interpro:IPR030425|refseq:NP_001230195.1|refseq:NP_076926.2|refseq:NP_683876.1|refseq:XP_016873398.1	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Suppl. fig. 3d.i|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:23jb2TxG9ldbR354eZD52FliblI9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:+HfLvmqJ0ro88Y/+YU8wvaaane0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15077	uniprotkb:P55060	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273784|imex:IM-26691-177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Suppl. fig. 3d.ii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:Pn4m+HhG+kZ8zY881D4e2hdg8jo	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y275	uniprotkb:P55060	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273792|imex:IM-26691-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Suppl. fig. 3d.iii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:qg3V+TeNOK40+92UaFRmSTIrRVE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H1C4	uniprotkb:P55060	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273800|imex:IM-26691-179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Suppl. fig. 3d.iv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:xMscEMDBof1ew4NATBHa0wyU2Og	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95183	uniprotkb:P55060	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273808|imex:IM-26691-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Suppl. fig. 3d.v|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:2OsuKM1Wr7cOygQbwH4+aUUGi8g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H1C4	uniprotkb:Q14974	intact:EBI-4401271|uniprotkb:O95764|uniprotkb:Q569H6|uniprotkb:Q710D4|ensembl:ENSP00000227471	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:un93b_human(display_long)|uniprotkb:UNC93B1(gene name)|psi-mi:UNC93B1(display_short)|uniprotkb:UNC93(gene name synonym)|uniprotkb:UNC93B(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273816|imex:IM-26691-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112192.2|ensembl:ENSG00000110057(gene)|ensembl:ENST00000227471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0034138"(toll-like receptor 3 signaling pathway)|go:"GO:0034154"(toll-like receptor 7 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR010291(Protein of unknown function DUF895, eukaryotic)|interpro:IPR043268|rcsb pdb:7C76|rcsb pdb:7CYN|reactome:R-HSA-1679131|reactome:R-HSA-5602415	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.vi|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:KG5h76GZKYHGsRSa+VoDFhbJkOc9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:NFzESk/uNr1Q4KDM5N5edHXptNA	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04233	uniprotkb:Q14974	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273824|imex:IM-26691-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.i|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:ubmtM0iw3jYrSCMLVdm9vonPgBU	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99558	uniprotkb:Q14974	intact:EBI-358011|uniprotkb:Q8IYN1|uniprotkb:A8K2D8|uniprotkb:D3DX67|ensembl:ENSP00000478552|ensembl:ENSP00000480974|ensembl:ENSP00000482657	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:m3k14_human(display_long)|uniprotkb:MAP3K14(gene name)|psi-mi:MAP3K14(display_short)|uniprotkb:NIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NIK(gene name synonym)|uniprotkb:NF-kappa-beta-inducing kinase(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273832|imex:IM-26691-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003945.2|refseq:XP_011523743.1|dip:DIP-27522N|ensembl:ENSG00000006062(gene)|ensembl:ENST00000344686(transcript)|ensembl:ENST00000376926(transcript)|ensembl:ENST00000617331(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051607"(defense response to virus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017425(Mitogen-activated protein kinase kinase kinase 14)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042787|mint:Q99558|rcsb pdb:4DN5|rcsb pdb:4G3D|rcsb pdb:4IDT|rcsb pdb:4IDV|rcsb pdb:6WPP|rcsb pdb:6Z1Q|rcsb pdb:6Z1T|reactome:R-HSA-389357|reactome:R-HSA-5607761|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5676594	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.ii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:GBmoUEm+pGubNnnauGgKgMyeiqA9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:6C7um1hkr95qWGhVOysKkvDOj4w	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15077	uniprotkb:Q14974	intact:EBI-10235794|uniprotkb:Q15754|ensembl:ENSP00000309771|ensembl:ENSP00000377215|ensembl:ENSP00000377216|ensembl:ENSP00000377217|ensembl:ENSP00000440770|ensembl:ENSP00000441079|ensembl:ENSP00000442551|ensembl:ENSP00000442990|ensembl:ENSP00000443427|ensembl:ENSP00000445652|ensembl:ENSP00000480966|ensembl:ENSP00000504879|ensembl:ENSP00000505646	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:p2ry6_human(display_long)|uniprotkb:P2RY6(gene name)|psi-mi:P2RY6(display_short)|uniprotkb:PP2891(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273840|imex:IM-26691-191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264133.1|refseq:NP_001264134.1|refseq:NP_001264135.1|refseq:NP_001264136.1|refseq:NP_001264137.1|refseq:NP_789766.1|refseq:NP_789767.1|refseq:NP_789768.1|refseq:XP_005274079.1|refseq:XP_006718634.1|refseq:XP_011543379.1|refseq:XP_011543381.1|ensembl:ENSG00000171631(gene)|ensembl:ENST00000349767(transcript)|ensembl:ENST00000393590(transcript)|ensembl:ENST00000393591(transcript)|ensembl:ENST00000393592(transcript)|ensembl:ENST00000535931(transcript)|ensembl:ENST00000538328(transcript)|ensembl:ENST00000540124(transcript)|ensembl:ENST00000540342(transcript)|ensembl:ENST00000542092(transcript)|ensembl:ENST00000544437(transcript)|ensembl:ENST00000618468(transcript)|ensembl:ENST00000679753(transcript)|ensembl:ENST00000680955(transcript)|go:"GO:0001621"(G protein-coupled ADP receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0045029"(G protein-coupled UDP receptor activity)|go:"GO:0045030"(G protein-coupled UTP receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001973(P2Y6 purinoceptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2B6R|reactome:R-HSA-416476|reactome:R-HSA-417957	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.iii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:epQoq9A5Ftfga4rAPkIj6Fxor289606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:k0ItFim856lCeS6jR8BXB8XHgKw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F5H1C8	uniprotkb:Q14974	intact:EBI-21259559|ensembl:ENSP00000445773	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:f5h1c8_human(display_long)|uniprotkb:SLC15A3(gene name)|psi-mi:SLC15A3(display_short)|uniprotkb:hCG_40399(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273848|imex:IM-26691-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110446(gene)|ensembl:ENST00000541505(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR036259	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.iv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:c7OFrnUepAK9VlRAcyO6oek6Bj49606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:wYfyJIj9FCwx2C2uEor1z+zaK0Q	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y275	uniprotkb:Q14974	intact:EBI-519169|ensembl:ENSP00000365048|uniprotkb:Q6FHD6|uniprotkb:Q7Z5J2|uniprotkb:E0ADT7	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:tn13b_human(display_long)|uniprotkb:TNF- and APOL-related leukocyte expressed ligand 1(gene name synonym)|uniprotkb:B lymphocyte stimulator(gene name synonym)|uniprotkb:B-cell-activating factor(gene name synonym)|uniprotkb:Dendritic cell-derived TNF-like molecule(gene name synonym)|uniprotkb:UNQ401/PRO738(orf name)|uniprotkb:TNFSF13B(gene name)|psi-mi:TNFSF13B(display_short)|uniprotkb:BAFF(gene name synonym)|uniprotkb:BLYS(gene name synonym)|uniprotkb:TALL1(gene name synonym)|uniprotkb:ZTNF4(gene name synonym)|uniprotkb:TNFSF20(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273856|imex:IM-26691-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102524(gene)|ensembl:ENST00000375887(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031296"(B cell costimulation)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1JH5|rcsb pdb:1KD7|rcsb pdb:1KXG|rcsb pdb:1OQD|rcsb pdb:1OQE|rcsb pdb:1OSG|rcsb pdb:3V56|rcsb pdb:4V46|rcsb pdb:4ZCH|rcsb pdb:5Y9J|rcsb pdb:6FXN|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-5676594|refseq:NP_001139117.1|refseq:NP_006564.1|dip:DIP-6225N	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Suppl. fig. 3e.v|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:T5yhbOL+R0RPM+Q6idolaFLqnpo9606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:ZghN8gQ5WgCrVljLKX2lvid+R2c	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3ZCQ2	uniprotkb:A5YKK6	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273864|imex:IM-26691-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Suppl. fig. 5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/17	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rigid:3szbOlgLPWoGfViaUovwKCzAH0c	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3ZCQ2	uniprotkb:A5YKK6	intact:EBI-21258284|ensembl:ENSP00000315915|ensembl:ENSP00000479862|uniprotkb:Q8NHX5	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	psi-mi:ax2r_human(display_long)|uniprotkb:ANXA2R(gene name)|psi-mi:ANXA2R(display_short)|uniprotkb:AX2R(gene name synonym)|uniprotkb:C5orf39(gene name synonym)|uniprotkb:Annexin II receptor(gene name synonym)	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21273885|imex:IM-26691-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177721(gene)|ensembl:ENST00000314890(transcript)|ensembl:ENST00000616064(transcript)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR031449|refseq:NP_001014301.1	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Suppl. fig. 5g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/01/08	2019/03/17	rogid:pfUab2lJXI481ANtjumrppW+H0I9606	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rigid:3szbOlgLPWoGfViaUovwKCzAH0c	false	tandem tag:n-n	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q9BZR8	uniprotkb:Q08380	intact:EBI-1385773|uniprotkb:Q96QR5|uniprotkb:Q9BZR7|uniprotkb:A8KAD0|ensembl:ENSP00000309132|ensembl:ENSP00000379653|ensembl:ENSP00000467086|ensembl:ENSP00000486050|ensembl:ENSP00000486796|ensembl:ENSP00000487330	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:b2l14_human(display_long)|uniprotkb:Apoptosis regulator Bcl-G(gene name synonym)|uniprotkb:BCL2L14(gene name)|psi-mi:BCL2L14(display_short)|uniprotkb:BCLG(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279435|imex:IM-26691-192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719214.1|refseq:XP_011519150.1|refseq:XP_011519151.1|refseq:NP_110393.1|refseq:NP_620048.1|refseq:NP_620049.1|refseq:XP_016875452.1|ensembl:ENSG00000121380(gene)|ensembl:ENSG00000281449(gene)|ensembl:ENST00000308721(transcript)|ensembl:ENST00000396367(transcript)|ensembl:ENST00000589718(transcript)|ensembl:ENST00000627413(transcript)|ensembl:ENST00000628783(transcript)|ensembl:ENST00000631317(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR033229|interpro:IPR036834|reactome:R-HSA-6803205	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.i|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:Fiejp4wLlCQA5hfsvLPFcnb1Xa89606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:yoD2Wp8fG0p85EN/cOyKXaG6erg	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q9NRD1	uniprotkb:Q08380	intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279445|imex:IM-26691-194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.ii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:6Zr8imjlnspLdxRal4OFODEbG3g	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:P20591	uniprotkb:Q08380	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279455|imex:IM-26691-196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.iii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:OaPuiO2khWDAY74nP/0nOGcLj3M	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q9Y3Z3	uniprotkb:Q08380	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279465|imex:IM-26691-198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.iv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:+nURNNr+tO/0sjgKxWiqCVRYDbk	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:O00220	uniprotkb:Q08380	intact:EBI-518861|uniprotkb:Q96E62|ensembl:ENSP00000221132|uniprotkb:A8K5I4|uniprotkb:Q53Y72	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:tr10a_human(display_long)|uniprotkb:Death receptor 4(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 1(gene name synonym)|uniprotkb:TNFRSF10A(gene name)|psi-mi:TNFRSF10A(display_short)|uniprotkb:APO2(gene name synonym)|uniprotkb:DR4(gene name synonym)|uniprotkb:TRAILR1(gene name synonym)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279475|imex:IM-26691-200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|mint:O00220|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENSG00000104689(gene)|ensembl:ENST00000221132(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005035"(death receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045569"(TRAIL binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|refseq:NP_003835.3	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.v|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:utFDDi1uRCNlMUCt29SYzzar6Sc9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:4F4TJGiAfWX9XGhjjWt/gS5eers	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:O95183	uniprotkb:Q08380	intact:EBI-10191195|uniprotkb:Q9P0T2|ensembl:ENSP00000305647	intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0	psi-mi:vamp5_human(display_long)|uniprotkb:VAMP5(gene name)|psi-mi:VAMP5(display_short)|uniprotkb:Myobrevin(gene name synonym)|uniprotkb:HSPC191(orf name)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hubel et al. (2019)	pubmed:30833792|imex:IM-26691	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21279485|imex:IM-26691-202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006625.1|ensembl:ENSG00000168899(gene)|ensembl:ENST00000306384(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855	ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1	-	-	-	figure legend:Supplementary figure 4a.vi|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/01/08	2019/03/20	rogid:HXiqZNJ6Ylqwe3N/JpvgvXBU0Sg9606	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	rigid:fooDq0tcLvwjq8sTgK+6624N0go	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)